MRM2 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
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Genes

343 genes differentially expressed following the MRM2 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
MAGEB3 melanoma antigen family B3 2.29177
SCN2B sodium channel, voltage gated, type II beta subunit 2.29177
PCDHB1 protocadherin beta 1 2.29177
HES3 hes family bHLH transcription factor 3 2.29177
SOX18 SRY (sex determining region Y)-box 18 2.29177
PNMA5 paraneoplastic Ma antigen family member 5 2.29177
OR10A2 olfactory receptor, family 10, subfamily A, member 2 2.29177
GJB3 gap junction protein, beta 3, 31kDa 2.29177
FFAR4 free fatty acid receptor 4 2.29177
OR2J3 olfactory receptor, family 2, subfamily J, member 3 2.29177
ARHGAP30 Rho GTPase activating protein 30 2.29177
IZUMO3 IZUMO family member 3 2.29177
CHRNG cholinergic receptor, nicotinic, gamma (muscle) 2.29177
CAPN14 calpain 14 2.29177
IZUMO4 IZUMO family member 4 2.29177
HHEX hematopoietically expressed homeobox 2.29177
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 2.29177
RAET1E retinoic acid early transcript 1E 2.29177
GPR4 G protein-coupled receptor 4 2.29177
HLF hepatic leukemia factor 2.29177
LURAP1L leucine rich adaptor protein 1-like 2.29177
ALB albumin 2.29177
PKDCC protein kinase domain containing, cytoplasmic 2.29177
CEP295NL CEP295 N-terminal like 2.29177
NFAM1 NFAT activating protein with ITAM motif 1 2.29177
RSPO3 R-spondin 3 2.29177
TTLL2 tubulin tyrosine ligase-like family member 2 2.29177
ACVRL1 activin A receptor type II-like 1 2.29177
C16ORF86 chromosome 16 open reading frame 86 2.29177
PCGF6 polycomb group ring finger 6 2.29177
CCDC38 coiled-coil domain containing 38 2.29177
YY2 YY2 transcription factor 2.29177
OR5V1 olfactory receptor, family 5, subfamily V, member 1 2.29177
HYDIN HYDIN, axonemal central pair apparatus protein 2.29177
MISP mitotic spindle positioning 2.29177
TRPC5OS TRPC5 opposite strand 2.29177
TTLL8 tubulin tyrosine ligase-like family member 8 2.29177
CD69 CD69 molecule 2.29177
SLC30A2 solute carrier family 30 (zinc transporter), member 2 2.29177
SNX3 sorting nexin 3 2.29177
RPE65 retinal pigment epithelium-specific protein 65kDa 2.29177
SSTR3 somatostatin receptor 3 2.29177
TAS2R1 taste receptor, type 2, member 1 2.29177
PLXNB1 plexin B1 2.29177
TRPV5 transient receptor potential cation channel, subfamily V, member 5 2.29177
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa 2.29177
MS4A15 membrane-spanning 4-domains, subfamily A, member 15 2.29177
OR2AJ1 olfactory receptor, family 2, subfamily AJ, member 1 2.29177
RSPH1 radial spoke head 1 homolog (Chlamydomonas) 2.29177
SPMIP9 sperm microtubule inner protein 9 2.29177
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 2.29177
TYROBP TYRO protein tyrosine kinase binding protein 2.29177
UBE4B ubiquitination factor E4B 2.29177
DUSP9 dual specificity phosphatase 9 2.29177
DNAAF1 dynein, axonemal, assembly factor 1 2.29177
STX18 syntaxin 18 2.29177
SLC2A7 solute carrier family 2 (facilitated glucose transporter), member 7 2.29177
MUSTN1 musculoskeletal, embryonic nuclear protein 1 2.29177
APOBEC3H apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H 2.29177
ANO3 anoctamin 3 2.29177
YIPF7 Yip1 domain family, member 7 2.29177
NECTIN1 nectin cell adhesion molecule 1 2.29177
INSYN1 inhibitory synaptic factor 1 2.29177
H3C13 H3 clustered histone 13 2.29177
SERTM2 serine rich and transmembrane domain containing 2 2.29177
SEPTIN12 septin 12 2.29177
GARIN1A golgi associated RAB2 interactor 1A 2.29177
DUSP29 dual specificity phosphatase 29 2.29177
CFAP157 cilia and flagella associated protein 157 2.29177
G6PC1 glucose-6-phosphatase catalytic subunit 1 2.29177
LORICRIN loricrin cornified envelope precursor protein 2.29177
SMIM36 small integral membrane protein 36 2.29177
PROX2 prospero homeobox 2 2.29177
WDR64 WD repeat domain 64 2.29177
ASB5 ankyrin repeat and SOCS box containing 5 2.29177
MYOG myogenin (myogenic factor 4) 2.29177
MYH15 myosin, heavy chain 15 2.29177
IL6 interleukin 6 2.29177
ZIC1 Zic family member 1 2.29177
NPIPB9 nuclear pore complex interacting protein family, member B9 2.29177
LIX1 Lix1 homolog (chicken) 2.29177
SPMAP1 sperm microtubule associated protein 1 2.29177
OR8D4 olfactory receptor, family 8, subfamily D, member 4 2.29177
NXPE2 neurexophilin and PC-esterase domain family, member 2 2.29177
CRLF2 cytokine receptor-like factor 2 2.29177
GJD2 gap junction protein, delta 2, 36kDa 2.29177
CDKN2A cyclin-dependent kinase inhibitor 2A 2.29177
GCSAM germinal center-associated, signaling and motility 2.29177
MAGIX MAGI family member, X-linked 2.29177
MROH5 maestro heat-like repeat family member 5 2.29177
DLK1 delta-like 1 homolog (Drosophila) 2.29177
OR2D3 olfactory receptor, family 2, subfamily D, member 3 2.29177
OR2D2 olfactory receptor, family 2, subfamily D, member 2 2.29177
OOSP1 oocyte secreted protein 1, pseudogene 2.29177
C7ORF57 chromosome 7 open reading frame 57 2.29177
SASH3 SAM and SH3 domain containing 3 2.29177
SBSN suprabasin 2.29177
TRIT1 tRNA isopentenyltransferase 1 2.29177
SHOX short stature homeobox 2.29177
MRPL42 mitochondrial ribosomal protein L42 2.29177
APOH apolipoprotein H (beta-2-glycoprotein I) 2.29177
FOXP2 forkhead box P2 2.29177
AMN amnion associated transmembrane protein 2.29177
FNDC8 fibronectin type III domain containing 8 2.29177
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 2.29177
OR56A3 olfactory receptor, family 56, subfamily A, member 3 2.29177
FGR FGR proto-oncogene, Src family tyrosine kinase 2.29177
NGB neuroglobin 2.29177
BMX BMX non-receptor tyrosine kinase 2.29177
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) 2.29177
DAW1 dynein assembly factor with WDR repeat domains 1 2.29177
ADGRD1 adhesion G protein-coupled receptor D1 2.29177
BOLL boule-like RNA-binding protein 2.29177
ZMYND10 zinc finger, MYND-type containing 10 2.29177
VAV1 vav 1 guanine nucleotide exchange factor 2.29177
ZNF514 zinc finger protein 514 2.29177
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled 2.29177
VSTM1 V-set and transmembrane domain containing 1 2.29177
EDN1 endothelin 1 2.29177
CSTA cystatin A (stefin A) 2.29177
IL1A interleukin 1, alpha 2.29177
GOLGA6B golgin A6 family, member B 2.29177
CCL19 chemokine (C-C motif) ligand 19 2.29177
DRD5 dopamine receptor D5 2.29177
PSKH2 protein serine kinase H2 2.29177
TDRD15 tudor domain containing 15 2.29177
CD52 CD52 molecule 2.29177
TMED6 transmembrane emp24 protein transport domain containing 6 2.29177
WFDC6 WAP four-disulfide core domain 6 2.29177
SLC22A24 solute carrier family 22, member 24 2.29177
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal) 2.29177
EFCAB9 EF-hand calcium binding domain 9 2.29177
ZNF596 zinc finger protein 596 2.29177
GRK7 G protein-coupled receptor kinase 7 2.29177
SCFD2 sec1 family domain containing 2 2.29177
P2RX6 purinergic receptor P2X, ligand gated ion channel, 6 2.29177
TAS2R50 taste receptor, type 2, member 50 2.29177
C2ORF66 chromosome 2 open reading frame 66 2.29177
OSM oncostatin M 2.29177
REM1 RAS (RAD and GEM)-like GTP-binding 1 2.29177
GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble) 2.29177
DMRTB1 DMRT-like family B with proline-rich C-terminal, 1 2.29177
ZNF396 zinc finger protein 396 2.29177
GOLGA8K golgin A8 family, member K 2.29177
OR14A2 olfactory receptor, family 14, subfamily A, member 2 2.29177
TRMT10A tRNA methyltransferase 10 homolog A (S. cerevisiae) 2.29177
MMP13 matrix metallopeptidase 13 2.29177
VMO1 vitelline membrane outer layer 1 homolog (chicken) 2.29177
NPC1L1 NPC1-like 1 2.29177
AMPD1 adenosine monophosphate deaminase 1 2.29177
PHOX2A paired-like homeobox 2a 2.29177
NDUFB9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa 2.29177
FGF4 fibroblast growth factor 4 2.29177
FGF5 fibroblast growth factor 5 2.29177
CFP complement factor properdin 2.29177
FAM161B family with sequence similarity 161, member B 2.29177
MEIG1 meiosis/spermiogenesis associated 1 2.29177
AMIGO3 adhesion molecule with Ig-like domain 3 2.29177
BTG1 B-cell translocation gene 1, anti-proliferative 2.29177
ADAM20 ADAM metallopeptidase domain 20 2.29177
C10ORF105 chromosome 10 open reading frame 105 2.29177
CD27 CD27 molecule 2.29177
BIN2 bridging integrator 2 2.29177
LAMP5 lysosomal-associated membrane protein family, member 5 2.29177
FGF16 fibroblast growth factor 16 2.29177
RNF222 ring finger protein 222 2.29177
PXT1 peroxisomal, testis specific 1 2.29177
CARNS1 carnosine synthase 1 2.29177
SLC7A4 solute carrier family 7, member 4 2.29177
TMPRSS12 transmembrane (C-terminal) protease, serine 12 2.29177
TMPRSS15 transmembrane protease, serine 15 2.29177
MGP matrix Gla protein 2.29177
FTL ferritin, light polypeptide 2.29177
PHYH phytanoyl-CoA 2-hydroxylase 2.29177
FLRT3 fibronectin leucine rich transmembrane protein 3 2.29177
TGM4 transglutaminase 4 2.29177
FRMPD1 FERM and PDZ domain containing 1 2.29177
ST18 suppression of tumorigenicity 18, zinc finger 2.29177
LYZL4 lysozyme-like 4 2.29177
NOBOX NOBOX oogenesis homeobox 2.29177
IFRD2 interferon-related developmental regulator 2 2.2877
ZSCAN2 zinc finger and SCAN domain containing 2 2.27648
GRIK2 glutamate receptor, ionotropic, kainate 2 2.27648
RALGAPA2 Ral GTPase activating protein, alpha subunit 2 (catalytic) 2.27495
DOC2B double C2-like domains, beta 2.19868
C4ORF51 chromosome 4 open reading frame 51 2.19868
DSCAML1 Down syndrome cell adhesion molecule like 1 2.19868
MBD5 methyl-CpG binding domain protein 5 2.19868
FIGNL1 fidgetin-like 1 2.1707
KLHL8 kelch-like family member 8 2.15404
TAFA5 TAFA chemokine like family member 5 2.14409
ZNF185 zinc finger protein 185 (LIM domain) 2.14409
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 2.14409
BCKDK branched chain ketoacid dehydrogenase kinase 2.14409
LPP LIM domain containing preferred translocation partner in lipoma 2.14409
PRR7 proline rich 7 (synaptic) 2.14409
DSP desmoplakin 2.14409
RPL5 ribosomal protein L5 2.14409
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) 2.14409
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6 2.14302
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3 2.13531
CTSB cathepsin B 2.12224
NCR1 natural cytotoxicity triggering receptor 1 2.11918
NAGS N-acetylglutamate synthase 2.11918
CA3 carbonic anhydrase III 2.11008
STX3 syntaxin 3 2.09843
RERE arginine-glutamic acid dipeptide (RE) repeats 2.09843
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 2.09843
PABIR2 PABIR family member 2 2.09843
PRDM2 PR domain containing 2, with ZNF domain 2.0878
RORA RAR-related orphan receptor A 2.0878
IGDCC4 immunoglobulin superfamily, DCC subclass, member 4 2.0878
INKA2 inka box actin regulator 2 2.08284
SH3PXD2B SH3 and PX domains 2B 2.04342
TMEM91 transmembrane protein 91 2.04194
BPNT2 3'(2'), 5'-bisphosphate nucleotidase 2 2.02685
CENPA centromere protein A 2.01414
ENO4 enolase family member 4 2.01414
DHDDS dehydrodolichyl diphosphate synthase 2.00311

decreased expression

Symbol Name Standardized Value
NUP93 nucleoporin 93kDa -2.29177
ZBTB44 zinc finger and BTB domain containing 44 -2.29177
TCF24 transcription factor 24 -2.29177
ULK4 unc-51 like kinase 4 -2.29177
ZHX1 zinc fingers and homeoboxes 1 -2.29177
TIMM21 translocase of inner mitochondrial membrane 21 homolog (yeast) -2.29177
NRG2 neuregulin 2 -2.29177
SPINT4 serine peptidase inhibitor, Kunitz type 4 -2.29177
TRIOBP TRIO and F-actin binding protein -2.29177
BMI1 BMI1 proto-oncogene, polycomb ring finger -2.29177
POM121C POM121 transmembrane nucleoporin C -2.29177
SYNJ1 synaptojanin 1 -2.29177
MSH2 mutS homolog 2 -2.29177
AKAP5 A kinase (PRKA) anchor protein 5 -2.29177
PRNP prion protein -2.29177
LAD1 ladinin 1 -2.29177
WIPI2 WD repeat domain, phosphoinositide interacting 2 -2.29177
PTPRN protein tyrosine phosphatase, receptor type, N -2.29177
TXNIP thioredoxin interacting protein -2.29177
DNAJB11 DnaJ (Hsp40) homolog, subfamily B, member 11 -2.29177
SLU7 SLU7 splicing factor homolog (S. cerevisiae) -2.29177
GLIS1 GLIS family zinc finger 1 -2.29177
MAP1S microtubule-associated protein 1S -2.29177
TRNP1 TMF1-regulated nuclear protein 1 -2.29177
SYCE3 synaptonemal complex central element protein 3 -2.29177
TGFB3 transforming growth factor, beta 3 -2.29177
HMBS hydroxymethylbilane synthase -2.29177
CASTOR1 cytosolic arginine sensor for mTORC1 subunit 1 -2.29177
AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 -2.29177
TEDC1 tubulin epsilon and delta complex 1 -2.29177
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2 -2.29177
NUP210L nucleoporin 210kDa-like -2.29177
MIF4GD MIF4G domain containing -2.29177
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 -2.29177
FKBPL FK506 binding protein like -2.29177
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome -2.29177
IL3RA interleukin 3 receptor, alpha (low affinity) -2.29177
TRAK1 trafficking protein, kinesin binding 1 -2.29177
SULT1C4 sulfotransferase family, cytosolic, 1C, member 4 -2.29177
ZNF875 zinc finger protein 875 -2.27495
EYS eyes shut homolog (Drosophila) -2.26828
IRGQ immunity-related GTPase family, Q -2.23848
KLHL2 kelch-like family member 2 -2.23663
PCSK9 proprotein convertase subtilisin/kexin type 9 -2.19868
RAB37 RAB37, member RAS oncogene family -2.1707
IPO5 importin 5 -2.1707
CIART circadian associated repressor of transcription -2.1707
RNF138 ring finger protein 138, E3 ubiquitin protein ligase -2.16799
TMEM63C transmembrane protein 63C -2.14409
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) -2.14409
HAS1 hyaluronan synthase 1 -2.14409
DUSP13B dual specificity phosphatase 13B -2.14409
BNC1 basonuclin 1 -2.14409
C9ORF43 chromosome 9 open reading frame 43 -2.14409
PNMA8C PNMA family member 8C -2.14409
REPS2 RALBP1 associated Eps domain containing 2 -2.14409
SPESP1 sperm equatorial segment protein 1 -2.14409
ACTL8 actin-like 8 -2.14409
PTPRQ protein tyrosine phosphatase, receptor type, Q -2.14409
CCDC13 coiled-coil domain containing 13 -2.14409
CD19 CD19 molecule -2.14409
C1QL3 complement component 1, q subcomponent-like 3 -2.14409
GLIPR1L1 GLI pathogenesis-related 1 like 1 -2.14409
PCDHA1 protocadherin alpha 1 -2.14409
ZNF267 zinc finger protein 267 -2.14409
DPEP1 dipeptidase 1 (renal) -2.14409
FOXD1 forkhead box D1 -2.14409
MRAP melanocortin 2 receptor accessory protein -2.14409
CFAP47 cilia and flagella associated protein 47 -2.14409
AGBL4 ATP/GTP binding protein-like 4 -2.14409
TTBK1 tau tubulin kinase 1 -2.14409
TMEM86B transmembrane protein 86B -2.14409
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) -2.14409
CARD9 caspase recruitment domain family, member 9 -2.14409
TULP2 tubby like protein 2 -2.14409
CANX calnexin -2.14409
CRHR1 corticotropin releasing hormone receptor 1 -2.14409
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type -2.14409
NLRC3 NLR family, CARD domain containing 3 -2.14409
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein -2.14409
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae) -2.14409
TBXA2R thromboxane A2 receptor -2.14409
BCL2L1 BCL2-like 1 -2.14409
TRIM54 tripartite motif containing 54 -2.14409
A1CF APOBEC1 complementation factor -2.14409
CISH cytokine inducible SH2-containing protein -2.14409
LGALS9 lectin, galactoside-binding, soluble, 9 -2.14409
CPLX1 complexin 1 -2.14409
IL17D interleukin 17D -2.14409
LY6G6D lymphocyte antigen 6 complex, locus G6D -2.14409
PCDHGA12 protocadherin gamma subfamily A, 12 -2.14409
ERVV-2 endogenous retrovirus group V, member 2 -2.14409
CYSRT1 cysteine-rich tail protein 1 -2.14409
DLX4 distal-less homeobox 4 -2.14409
DCTN2 dynactin 2 (p50) -2.14409
MEIOB meiosis specific with OB domains -2.14409
IRX1 iroquois homeobox 1 -2.14409
PLCB2 phospholipase C, beta 2 -2.14302
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5 -2.14045
PPP1R35 protein phosphatase 1, regulatory subunit 35 -2.13531
CDK18 cyclin-dependent kinase 18 -2.12224
PHKA2 phosphorylase kinase, alpha 2 (liver) -2.1131
LTBP1 latent transforming growth factor beta binding protein 1 -2.09843
XPC xeroderma pigmentosum, complementation group C -2.09294
CENPV centromere protein V -2.09294
RHEB Ras homolog enriched in brain -2.08968
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 -2.08741
ZNF146 zinc finger protein 146 -2.06012
NCLN nicalin -2.05507
DCDC2C doublecortin domain containing 2C -2.05507
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8 -2.05313
GK glycerol kinase -2.05313
SAC3D1 SAC3 domain containing 1 -2.05168
GTSF1 gametocyte specific factor 1 -2.05092
SLCO1B1 solute carrier organic anion transporter family, member 1B1 -2.05092
ECEL1 endothelin converting enzyme-like 1 -2.05092
LIF leukemia inhibitory factor -2.05092
BEST1 bestrophin 1 -2.05092
CADM3 cell adhesion molecule 3 -2.04779
NUDT17 nudix (nucleoside diphosphate linked moiety X)-type motif 17 -2.03904
OVOL1 ovo-like zinc finger 1 -2.03904
MMP28 matrix metallopeptidase 28 -2.01937
GPR18 G protein-coupled receptor 18 -2.01897
PCOLCE2 procollagen C-endopeptidase enhancer 2 -2.01414