MRM3 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description mitochondrial rRNA methyltransferase 3 (NCBI Entrez Gene Database, 55178)
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Genes

362 genes differentially expressed following the MRM3 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
OR9H1 olfactory receptor family 9 subfamily H member 1 pseudogene (gene/pseudogene) 3.68575
GLRA3 glycine receptor, alpha 3 3.68575
MBOAT4 membrane bound O-acyltransferase domain containing 4 3.68575
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8 3.68575
MLANA melan-A 3.68575
PAX5 paired box 5 3.68575
TCERG1L transcription elongation regulator 1-like 3.68575
ASB15 ankyrin repeat and SOCS box containing 15 3.68575
SLC16A11 solute carrier family 16, member 11 3.68575
CA1 carbonic anhydrase I 3.68575
ANKS4B ankyrin repeat and sterile alpha motif domain containing 4B 3.68575
KCNT1 potassium channel, sodium activated subfamily T, member 1 3.68575
CD1D CD1d molecule 3.68575
SPATA22 spermatogenesis associated 22 3.68575
TTLL2 tubulin tyrosine ligase-like family member 2 3.68575
SIX6 SIX homeobox 6 3.68575
KLHL35 kelch-like family member 35 3.68575
PTCRA pre T-cell antigen receptor alpha 3.68575
ERAS ES cell expressed Ras 3.68575
TMEM238L transmembrane protein 238 like 3.68575
VIT vitrin 3.68575
CFAP107 cilia and flagella associated protein 107 3.68575
MEIS1 Meis homeobox 1 3.68575
CD5 CD5 molecule 3.68575
KLHDC1 kelch domain containing 1 3.68575
UGT2B4 UDP glucuronosyltransferase 2 family, polypeptide B4 3.68575
CX3CL1 chemokine (C-X3-C motif) ligand 1 3.67887
PDIA2 protein disulfide isomerase family A, member 2 3.67887
TM4SF1 transmembrane 4 L six family member 1 3.67887
HES3 hes family bHLH transcription factor 3 3.67887
ZNF492 zinc finger protein 492 3.67887
TMPRSS11D transmembrane protease, serine 11D 3.67887
RNF17 ring finger protein 17 3.67887
SLC6A19 solute carrier family 6 (neutral amino acid transporter), member 19 3.67887
GNG13 guanine nucleotide binding protein (G protein), gamma 13 3.67887
LY86 lymphocyte antigen 86 3.67887
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites 3.67887
MYBPHL myosin binding protein H-like 3.67887
LAX1 lymphocyte transmembrane adaptor 1 3.67887
HYAL4 hyaluronoglucosaminidase 4 3.67887
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 3.67887
AZGP1 alpha-2-glycoprotein 1, zinc-binding 3.67887
F7 coagulation factor VII (serum prothrombin conversion accelerator) 3.67887
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 3.67887
TMEM71 transmembrane protein 71 3.67887
OCSTAMP osteoclast stimulatory transmembrane protein 3.67887
LRRC69 leucine rich repeat containing 69 3.67887
VSX1 visual system homeobox 1 3.67887
TAS2R13 taste receptor, type 2, member 13 3.67887
AVP arginine vasopressin 3.67887
MYO1A myosin IA 3.67887
POSTN periostin, osteoblast specific factor 3.67887
SPRR1B small proline-rich protein 1B 3.67887
DEFB106B defensin, beta 106B 3.67887
NRAP nebulin-related anchoring protein 3.67887
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11 3.67887
EPB42 erythrocyte membrane protein band 4.2 3.67887
WT1 Wilms tumor 1 3.67887
PAX7 paired box 7 3.67887
FAM90A1 family with sequence similarity 90, member A1 3.67887
FOLR3 folate receptor 3 (gamma) 3.67887
SSTR3 somatostatin receptor 3 3.67887
GFI1 growth factor independent 1 transcription repressor 3.67887
OR4D9 olfactory receptor, family 4, subfamily D, member 9 3.67887
TPBGL trophoblast glycoprotein-like 3.67887
SPMAP1 sperm microtubule associated protein 1 3.67887
GBP3 guanylate binding protein 3 3.67887
LTB4R2 leukotriene B4 receptor 2 3.67887
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 3.67887
ABCC12 ATP-binding cassette, sub-family C (CFTR/MRP), member 12 3.67887
PROX2 prospero homeobox 2 3.67887
GC group-specific component (vitamin D binding protein) 3.67887
DOK7 docking protein 7 3.67887
TCIM transcriptional and immune response regulator 3.67887
HTR3C 5-hydroxytryptamine (serotonin) receptor 3C, ionotropic 3.67887
ARL14EPL ADP-ribosylation factor-like 14 effector protein-like 3.67887
OTOF otoferlin 3.67887
PLG plasminogen 3.67887
ELFN2 extracellular leucine-rich repeat and fibronectin type III domain containing 2 3.67887
CSNK2A2IP casein kinase 2 subunit alpha' interacting protein 3.67887
SPATA31H1 SPATA31 subfamily H member 1 3.67887
FAM240A family with sequence similarity 240 member A 3.67887
IRF2-DT IRF2 divergent transcript 3.67887
H3-7 H3.7 histone (putative) 3.67887
LHFPL7 LHFPL tetraspan subfamily member 7 3.67887
DEFB131B defensin beta 131B 3.67887
DIPK2B divergent protein kinase domain 2B 3.67887
GGTA1 glycoprotein alpha-galactosyltransferase 1 (inactive) 3.67887
PHF24 PHD finger protein 24 3.67887
GATA6 GATA binding protein 6 3.67887
C4ORF50 chromosome 4 open reading frame 50 3.67887
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 3.67887
NHLRC4 NHL repeat containing 4 3.67887
OR1C1 olfactory receptor, family 1, subfamily C, member 1 3.67887
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 3.67887
TEX101 testis expressed 101 3.67887
DMP1 dentin matrix acidic phosphoprotein 1 3.67887
DNMT3L DNA (cytosine-5-)-methyltransferase 3-like 3.67887
CYP26C1 cytochrome P450, family 26, subfamily C, polypeptide 1 3.67887
RAET1E retinoic acid early transcript 1E 3.67887
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6 3.67887
C1QL2 complement component 1, q subcomponent-like 2 3.67887
CREB3L3 cAMP responsive element binding protein 3-like 3 3.67887
PRR18 proline rich 18 3.67887
SYT15 synaptotagmin XV 3.67887
ACE2 angiotensin I converting enzyme 2 3.67887
ZNF683 zinc finger protein 683 3.67887
NPIPB8 nuclear pore complex interacting protein family, member B8 3.67887
GPR85 G protein-coupled receptor 85 3.67887
LRRC72 leucine rich repeat containing 72 3.67887
FGFBP2 fibroblast growth factor binding protein 2 3.67887
ABHD15 abhydrolase domain containing 15 3.67887
GJD2 gap junction protein, delta 2, 36kDa 3.67887
GJD4 gap junction protein, delta 4, 40.1kDa 3.67887
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 3.67887
NT5C1B 5'-nucleotidase, cytosolic IB 3.67887
KRT3 keratin 3, type II 3.67887
NACA2 nascent polypeptide-associated complex alpha subunit 2 3.67887
FNDC9 fibronectin type III domain containing 9 3.67887
KCNK4 potassium channel, two pore domain subfamily K, member 4 3.67887
SPEF1 sperm flagellar 1 3.67887
MRGPRE MAS-related GPR, member E 3.67887
ZNF703 zinc finger protein 703 3.67887
OR56A3 olfactory receptor, family 56, subfamily A, member 3 3.67887
VAX2 ventral anterior homeobox 2 3.67887
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled 3.67887
PHOSPHO1 phosphatase, orphan 1 3.67887
POTEJ POTE ankyrin domain family, member J 3.67887
DAND5 DAN domain family member 5, BMP antagonist 3.67887
CARNS1 carnosine synthase 1 3.67887
FAM25G family with sequence similarity 25, member G 3.67887
DLX5 distal-less homeobox 5 3.67887
CALML5 calmodulin-like 5 3.67887
FCRL6 Fc receptor-like 6 3.67887
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion 3.67887
SPATA9 spermatogenesis associated 9 3.67887
ZBP1 Z-DNA binding protein 1 3.67887
HAVCR1 hepatitis A virus cellular receptor 1 3.67887
TPSB2 tryptase beta 2 (gene/pseudogene) 3.67887
FAM177B family with sequence similarity 177, member B 3.67887
LMOD3 leiomodin 3 (fetal) 3.67887
WNT7B wingless-type MMTV integration site family, member 7B 3.67887
C16ORF78 chromosome 16 open reading frame 78 3.67887
PAGE4 P antigen family, member 4 (prostate associated) 3.67887
IL36R interleukin 36 receptor 3.67887
CCDC179 coiled-coil domain containing 179 3.67887
ISL2 ISL LIM homeobox 2 3.67887
SCML4 sex comb on midleg-like 4 (Drosophila) 3.67887
NUPR1 nuclear protein, transcriptional regulator, 1 3.67887
ZNF541 zinc finger protein 541 3.67887
TNR tenascin R 3.67887
DQX1 DEAQ box RNA-dependent ATPase 1 3.67887
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D 3.67887
DHH desert hedgehog 3.67887
ANKRD63 ankyrin repeat domain 63 3.67887
TEX19 testis expressed 19 3.67887
CGB2 chorionic gonadotropin, beta polypeptide 2 3.67887
VPREB3 pre-B lymphocyte 3 3.67887
DDI1 DNA-damage inducible 1 homolog 1 (S. cerevisiae) 3.67887
SDSL serine dehydratase-like 3.67887
ETV3L ets variant 3-like 3.67887
MNX1 motor neuron and pancreas homeobox 1 3.67887
FKBP1C FK506 binding protein 1C 3.67887
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 3.67887
GALNTL5 polypeptide N-acetylgalactosaminyltransferase-like 5 3.67887
TRAF3IP3 TRAF3 interacting protein 3 3.67887
LANCL3 LanC lantibiotic synthetase component C-like 3 (bacterial) 3.67887
OR14A2 olfactory receptor, family 14, subfamily A, member 2 3.67887
PDK4 pyruvate dehydrogenase kinase, isozyme 4 3.67887
CACNG3 calcium channel, voltage-dependent, gamma subunit 3 3.67887
ANXA2R annexin A2 receptor 3.67887
FXYD2 FXYD domain containing ion transport regulator 2 3.67887
BTG4 B-cell translocation gene 4 3.67887
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 3.67887
FGF6 fibroblast growth factor 6 3.67887
INSM1 insulinoma-associated 1 3.67887
WFDC10A WAP four-disulfide core domain 10A 3.67887
IDI2 isopentenyl-diphosphate delta isomerase 2 3.67887
SULT1C3 sulfotransferase family, cytosolic, 1C, member 3 3.67887
LGALS12 lectin, galactoside-binding, soluble, 12 3.67887
GALNT5 polypeptide N-acetylgalactosaminyltransferase 5 3.67887
HMX1 H6 family homeobox 1 3.67887
TMEM132C transmembrane protein 132C 3.67887
SLX1A SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae) 3.67887
CIB3 calcium and integrin binding family member 3 3.67887
MYADML2 myeloid-associated differentiation marker-like 2 3.67887
CFB complement factor B 3.67887
BPIFC BPI fold containing family C 3.67887
SPHK1 sphingosine kinase 1 3.59738
SOX21 SRY (sex determining region Y)-box 21 3.59738
PDE4D phosphodiesterase 4D, cAMP-specific 3.53391
SMAD3 SMAD family member 3 3.25069
MAN2A2 mannosidase, alpha, class 2A, member 2 3.16642
RPL11 ribosomal protein L11 3.11998
ATF7 activating transcription factor 7 3.09531
B4GALT3 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3 2.97872
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 2.91431
ZNF84 zinc finger protein 84 2.71549
SHISA6 shisa family member 6 2.63928
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 2.62481
FKBP15 FK506 binding protein 15, 133kDa 2.56749
CLHC1 clathrin heavy chain linker domain containing 1 2.56749
FNDC7 fibronectin type III domain containing 7 2.53437
KANK4 KN motif and ankyrin repeat domains 4 2.53437
AKR1D1 aldo-keto reductase family 1, member D1 2.53437
ZFP92 ZFP92 zinc finger protein 2.53437
SYNGR2 synaptogyrin 2 2.48592
SRPRA SRP receptor subunit alpha 2.46409
IRX3 iroquois homeobox 3 2.46409
FAM161A family with sequence similarity 161, member A 2.46409
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 2.38308
TSPAN17 tetraspanin 17 2.3733
YJU2 YJU2 splicing factor homolog 2.36015
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A 2.3437
KCNJ10 potassium channel, inwardly rectifying subfamily J, member 10 2.33923
MBD6 methyl-CpG binding domain protein 6 2.33923
PTH2 parathyroid hormone 2 2.33923
CD300A CD300a molecule 2.33923
CYP2C18 cytochrome P450, family 2, subfamily C, polypeptide 18 2.31979
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 2.31979
COG4 component of oligomeric golgi complex 4 2.31383
GPM6A glycoprotein M6A 2.30117
SAP130 Sin3A-associated protein, 130kDa 2.28715
USP2 ubiquitin specific peptidase 2 2.26443
RNF103 ring finger protein 103 2.26396
LAS1L LAS1-like (S. cerevisiae) 2.25071
MRPS18B mitochondrial ribosomal protein S18B 2.24789
DMTF1 cyclin D binding myb-like transcription factor 1 2.24453
DNAJC27 DnaJ (Hsp40) homolog, subfamily C, member 27 2.24453
CCT4 chaperonin containing TCP1, subunit 4 (delta) 2.24453
ACSF3 acyl-CoA synthetase family member 3 2.23894
ZNF76 zinc finger protein 76 2.23514
DCAKD dephospho-CoA kinase domain containing 2.22396
RPL36 ribosomal protein L36 2.20967
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2 2.17693
EPN2 epsin 2 2.17199
ACTN2 actinin, alpha 2 2.14747
RAB3C RAB3C, member RAS oncogene family 2.14352
PLAC9 placenta-specific 9 2.14085
DTX4 deltex 4, E3 ubiquitin ligase 2.14085
TBXAS1 thromboxane A synthase 1 (platelet) 2.13084
ERV3-1-ZNF117 ERV3-1-ZNF117 readthrough 2.12326
CNTNAP3B contactin associated protein-like 3B 2.11943
PTPRQ protein tyrosine phosphatase, receptor type, Q 2.11288
RPL29 ribosomal protein L29 2.11288
FPGS folylpolyglutamate synthase 2.09505
MKKS McKusick-Kaufman syndrome 2.06976
DNAJC19 DnaJ (Hsp40) homolog, subfamily C, member 19 2.06976
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta 2.06519
NOL11 nucleolar protein 11 2.05759
ZNF19 zinc finger protein 19 2.05518
MDH1 malate dehydrogenase 1, NAD (soluble) 2.0478
SLA2 Src-like-adaptor 2 2.04155
TSC22D1 TSC22 domain family, member 1 2.03675
LRRTM2 leucine rich repeat transmembrane neuronal 2 2.03587
NUDCD1 NudC domain containing 1 2.03587
SSH3 slingshot protein phosphatase 3 2.02669
DYNLT2 dynein light chain Tctex-type 2 2.02263
OLFM1 olfactomedin 1 2.00927

decreased expression

Symbol Name Standardized Value
EFCAB8 EF-hand calcium binding domain 8 -3.68575
RHOV ras homolog family member V -3.68575
PCDHB4 protocadherin beta 4 -3.68575
EBNA1BP2 EBNA1 binding protein 2 -3.67887
WNT16 wingless-type MMTV integration site family, member 16 -3.67887
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 -3.67887
CHAD chondroadherin -3.67887
TGM4 transglutaminase 4 -3.67887
CLEC19A C-type lectin domain family 19, member A -3.67887
NME8 NME/NM23 family member 8 -3.67887
SLC22A9 solute carrier family 22 (organic anion transporter), member 9 -3.67887
CPLX4 complexin 4 -3.67887
HBA1 hemoglobin, alpha 1 -3.67887
PRSS36 protease, serine, 36 -3.67887
CIITA class II, major histocompatibility complex, transactivator -3.67887
ASPA aspartoacylase -3.67887
C9ORF152 chromosome 9 open reading frame 152 -3.67887
CAPN9 calpain 9 -3.67887
CRTAC1 cartilage acidic protein 1 -3.67887
AICDA activation-induced cytidine deaminase -3.67887
PCDHGA9 protocadherin gamma subfamily A, 9 -3.67887
FNDC1 fibronectin type III domain containing 1 -3.67887
DUSP29 dual specificity phosphatase 29 -3.67887
ISL1 ISL LIM homeobox 1 -3.67887
CNR2 cannabinoid receptor 2 (macrophage) -3.67887
DRC1 dynein regulatory complex subunit 1 -3.67887
PRM1 protamine 1 -3.67887
ZNF831 zinc finger protein 831 -3.67887
CCDC177 coiled-coil domain containing 177 -3.67887
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) -3.59738
EIF3A eukaryotic translation initiation factor 3, subunit A -3.23678
LHCGR luteinizing hormone/choriogonadotropin receptor -3.16642
SLC47A2 solute carrier family 47 (multidrug and toxin extrusion), member 2 -3.10705
ACER3 alkaline ceramidase 3 -3.04959
SNX21 sorting nexin family member 21 -2.99976
GPRC5B G protein-coupled receptor, class C, group 5, member B -2.97079
BRPF3 bromodomain and PHD finger containing, 3 -2.91552
TAOK3 TAO kinase 3 -2.91393
STYK1 serine/threonine/tyrosine kinase 1 -2.90558
BLTP3B bridge-like lipid transfer protein family member 3B -2.90267
PMPCB peptidase (mitochondrial processing) beta -2.85961
SELENOK selenoprotein K -2.85857
BBOF1 basal body orientation factor 1 -2.78946
MYO6 myosin VI -2.7739
BRWD3 bromodomain and WD repeat domain containing 3 -2.62265
TBCE tubulin folding cofactor E -2.61639
CNOT11 CCR4-NOT transcription complex, subunit 11 -2.58963
SYT12 synaptotagmin XII -2.52376
CARD11 caspase recruitment domain family, member 11 -2.50221
SLCO1A2 solute carrier organic anion transporter family, member 1A2 -2.49088
FAS Fas cell surface death receptor -2.46409
PTGER3 prostaglandin E receptor 3 (subtype EP3) -2.46409
ADPRH ADP-ribosylarginine hydrolase -2.42828
HMBOX1 homeobox containing 1 -2.41775
FAM209B family with sequence similarity 209, member B -2.41516
KCTD15 potassium channel tetramerization domain containing 15 -2.40092
KIAA1586 KIAA1586 -2.38753
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase -2.34484
CFAP95 cilia and flagella associated protein 95 -2.33923
ANAPC15 anaphase promoting complex subunit 15 -2.33923
GATAD2A GATA zinc finger domain containing 2A -2.33923
TRIM16 tripartite motif containing 16 -2.33748
LINS1 lines homolog 1 -2.32464
OSBPL10 oxysterol binding protein-like 10 -2.31979
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 -2.31979
ZNF724 zinc finger protein 724 -2.31279
PRLR prolactin receptor -2.29902
ATG16L2 autophagy related 16-like 2 (S. cerevisiae) -2.27255
FAM161B family with sequence similarity 161, member B -2.26913
H4C13 H4 clustered histone 13 -2.26396
FHL2 four and a half LIM domains 2 -2.26257
CC2D2A coiled-coil and C2 domain containing 2A -2.24453
SYNPO2L synaptopodin 2-like -2.24453
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 -2.24453
OR2AG2 olfactory receptor, family 2, subfamily AG, member 2 -2.24453
CENPH centromere protein H -2.24453
DKK2 dickkopf WNT signaling pathway inhibitor 2 -2.24453
CEP89 centrosomal protein 89kDa -2.24383
CSTPP1 centriolar satellite-associated tubulin polyglutamylase complex regulator 1 -2.22625
PRSS3 protease, serine, 3 -2.22396
TICRR TOPBP1-interacting checkpoint and replication regulator -2.22318
PLIN3 perilipin 3 -2.19202
CCDC88A coiled-coil domain containing 88A -2.18657
PDE1A phosphodiesterase 1A, calmodulin-dependent -2.18273
ANO6 anoctamin 6 -2.17216
CAPS2 calcyphosine 2 -2.1649
DBNL drebrin-like -2.15977
HAS3 hyaluronan synthase 3 -2.13581
EXOSC8 exosome component 8 -2.13084
MFSD6 major facilitator superfamily domain containing 6 -2.12326
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial) -2.11501
MRPL54 mitochondrial ribosomal protein L54 -2.10168
ZNF547 zinc finger protein 547 -2.09882
FAM50B family with sequence similarity 50, member B -2.08486
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha -2.07678
SYNJ2 synaptojanin 2 -2.05907
CHN1 chimerin 1 -2.05759
KCNIP4 Kv channel interacting protein 4 -2.0478
BTN2A2 butyrophilin, subfamily 2, member A2 -2.02993
C1QL1 complement component 1, q subcomponent-like 1 -2.02696
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase -2.00927
ZNF557 zinc finger protein 557 -2.00927
PCSK5 proprotein convertase subtilisin/kexin type 5 -2.00767