MRPL39 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description mitochondrial ribosomal protein L39|Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Two transcript variants encoding distinct isoforms have been described. A pseudogene corresponding to this gene is found on chromosome 5q. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 54148)
External Link http://www.ncbi.nlm.nih.gov/gene/54148
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Genes

265 interacting proteins for MRPL39 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
AARS2 alanyl-tRNA synthetase 2, mitochondrial
AASS aminoadipate-semialdehyde synthase
ABCB7 ATP-binding cassette, sub-family B (MDR/TAP), member 7
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3
ACAD9 acyl-CoA dehydrogenase family, member 9
ACADVL acyl-CoA dehydrogenase, very long chain
ACOT9 acyl-CoA thioesterase 9
ADCK3 aarF domain containing kinase 3
AFG3L2 AFG3-like AAA ATPase 2
AGK acylglycerol kinase
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1
ALDH18A1 aldehyde dehydrogenase 18 family, member A1
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ALDH1L2 aldehyde dehydrogenase 1 family, member L2
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
AP2M1 adaptor-related protein complex 2, mu 1 subunit
ARCN1 archain 1
ATAD3A ATPase family, AAA domain containing 3A
ATAD3B ATPase family, AAA domain containing 3B
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1
ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1
ATP5H ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d
ATP5L ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G
C10ORF2 chromosome 10 open reading frame 2
C1QBP complement component 1, q subcomponent binding protein
C6ORF203 chromosome 6 open reading frame 203
CAND1 cullin-associated and neddylation-dissociated 1
CBWD2 COBW domain containing 2
CCT7 chaperonin containing TCP1, subunit 7 (eta)
CDK1 cyclin-dependent kinase 1
CECR5 cat eye syndrome chromosome region, candidate 5
CHCHD1 coiled-coil-helix-coiled-coil-helix domain containing 1
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
COX4I1 cytochrome c oxidase subunit IV isoform 1
CPT2 carnitine palmitoyltransferase 2
CUL3 cullin 3
DAP3 death associated protein 3
DBT dihydrolipoamide branched chain transacylase E2
DDX28 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
DHX30 DEAH (Asp-Glu-Ala-His) box helicase 30
DLD dihydrolipoamide dehydrogenase
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
ECH1 enoyl CoA hydratase 1, peroxisomal
ECI1 enoyl-CoA delta isomerase 1
ERAL1 Era-like 12S mitochondrial rRNA chaperone 1
ERLIN2 ER lipid raft associated 2
ERP44 endoplasmic reticulum protein 44
ETFA electron-transfer-flavoprotein, alpha polypeptide
FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial
FARSA phenylalanyl-tRNA synthetase, alpha subunit
FASTKD1 FAST kinase domains 1
FASTKD2 FAST kinase domains 2
FLAD1 flavin adenine dinucleotide synthetase 1
GADD45GIP1 growth arrest and DNA-damage-inducible, gamma interacting protein 1
GLDC glycine dehydrogenase (decarboxylating)
GLUD1 glutamate dehydrogenase 1
GRPEL1 GrpE-like 1, mitochondrial (E. coli)
GRSF1 G-rich RNA sequence binding factor 1
GTPBP10 GTP-binding protein 10 (putative)
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
HARS2 histidyl-tRNA synthetase 2, mitochondrial
HIGD1A HIG1 hypoxia inducible domain family, member 1A
HK1 hexokinase 1
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10
HSPA1B heat shock 70kDa protein 1B
HSPA9 heat shock 70kDa protein 9 (mortalin)
HSPD1 heat shock 60kDa protein 1 (chaperonin)
ICT1 immature colon carcinoma transcript 1
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
ILF3 interleukin enhancer binding factor 3, 90kDa
IMMT inner membrane protein, mitochondrial
ISCA1 iron-sulfur cluster assembly 1
KARS lysyl-tRNA synthetase
KIAA0391 KIAA0391
KRT18 keratin 18, type I
KRT19 keratin 19, type I
KRT8 keratin 8, type II
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
LETM1 leucine zipper-EF-hand containing transmembrane protein 1
LONP1 lon peptidase 1, mitochondrial
LRPPRC leucine-rich pentatricopeptide repeat containing
LRRC47 leucine rich repeat containing 47
MALSU1 mitochondrial assembly of ribosomal large subunit 1
MARC1 mitochondrial amidoxime reducing component 1
MCAT malonyl CoA:ACP acyltransferase (mitochondrial)
MCCC2 methylcrotonoyl-CoA carboxylase 2 (beta)
MCU mitochondrial calcium uniporter
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial
METTL17 methyltransferase like 17
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type
MOV10 Mov10 RISC complex RNA helicase
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MRPL1 mitochondrial ribosomal protein L1
MRPL10 mitochondrial ribosomal protein L10
MRPL11 mitochondrial ribosomal protein L11
MRPL12 mitochondrial ribosomal protein L12
MRPL13 mitochondrial ribosomal protein L13
MRPL14 mitochondrial ribosomal protein L14
MRPL15 mitochondrial ribosomal protein L15
MRPL16 mitochondrial ribosomal protein L16
MRPL17 mitochondrial ribosomal protein L17
MRPL18 mitochondrial ribosomal protein L18
MRPL19 mitochondrial ribosomal protein L19
MRPL2 mitochondrial ribosomal protein L2
MRPL20 mitochondrial ribosomal protein L20
MRPL21 mitochondrial ribosomal protein L21
MRPL22 mitochondrial ribosomal protein L22
MRPL24 mitochondrial ribosomal protein L24
MRPL27 mitochondrial ribosomal protein L27
MRPL28 mitochondrial ribosomal protein L28
MRPL3 mitochondrial ribosomal protein L3
MRPL32 mitochondrial ribosomal protein L32
MRPL37 mitochondrial ribosomal protein L37
MRPL38 mitochondrial ribosomal protein L38
MRPL4 mitochondrial ribosomal protein L4
MRPL40 mitochondrial ribosomal protein L40
MRPL41 mitochondrial ribosomal protein L41
MRPL43 mitochondrial ribosomal protein L43
MRPL44 mitochondrial ribosomal protein L44
MRPL46 mitochondrial ribosomal protein L46
MRPL47 mitochondrial ribosomal protein L47
MRPL48 mitochondrial ribosomal protein L48
MRPL49 mitochondrial ribosomal protein L49
MRPL50 mitochondrial ribosomal protein L50
MRPL51 mitochondrial ribosomal protein L51
MRPL52 mitochondrial ribosomal protein L52
MRPL54 mitochondrial ribosomal protein L54
MRPL55 mitochondrial ribosomal protein L55
MRPL9 mitochondrial ribosomal protein L9
MRPS10 mitochondrial ribosomal protein S10
MRPS11 mitochondrial ribosomal protein S11
MRPS14 mitochondrial ribosomal protein S14
MRPS15 mitochondrial ribosomal protein S15
MRPS16 mitochondrial ribosomal protein S16
MRPS17 mitochondrial ribosomal protein S17
MRPS18A mitochondrial ribosomal protein S18A
MRPS18B mitochondrial ribosomal protein S18B
MRPS2 mitochondrial ribosomal protein S2
MRPS21 mitochondrial ribosomal protein S21
MRPS22 mitochondrial ribosomal protein S22
MRPS23 mitochondrial ribosomal protein S23
MRPS24 mitochondrial ribosomal protein S24
MRPS25 mitochondrial ribosomal protein S25
MRPS26 mitochondrial ribosomal protein S26
MRPS27 mitochondrial ribosomal protein S27
MRPS28 mitochondrial ribosomal protein S28
MRPS30 mitochondrial ribosomal protein S30
MRPS31 mitochondrial ribosomal protein S31
MRPS34 mitochondrial ribosomal protein S34
MRPS35 mitochondrial ribosomal protein S35
MRPS5 mitochondrial ribosomal protein S5
MRPS6 mitochondrial ribosomal protein S6
MRPS7 mitochondrial ribosomal protein S7
MRPS9 mitochondrial ribosomal protein S9
MRRF mitochondrial ribosome recycling factor
MTG1 mitochondrial ribosome-associated GTPase 1
MTIF2 mitochondrial translational initiation factor 2
MTPAP mitochondrial poly(A) polymerase
MUT methylmalonyl CoA mutase
NDUFA13 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
NDUFA9 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa
NDUFAF3 NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)
NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
NGRN neugrin, neurite outgrowth associated
NIPSNAP1 nipsnap homolog 1 (C. elegans)
NME4 NME/NM23 nucleoside diphosphate kinase 4
NOA1 nitric oxide associated 1
NONO non-POU domain containing, octamer-binding
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NSUN4 NOP2/Sun domain family, member 4
NUP93 nucleoporin 93kDa
OAT ornithine aminotransferase
OXA1L oxidase (cytochrome c) assembly 1-like
PAN2 PAN2 poly(A) specific ribonuclease subunit
PAN3 PAN3 poly(A) specific ribonuclease subunit
PARS2 prolyl-tRNA synthetase 2, mitochondrial (putative)
PCCB propionyl CoA carboxylase, beta polypeptide
PDK3 pyruvate dehydrogenase kinase, isozyme 3
PFDN2 prefoldin subunit 2
PGAM5 phosphoglycerate mutase family member 5
PHB prohibitin
PHB2 prohibitin 2
PLEC plectin
PMPCA peptidase (mitochondrial processing) alpha
PMPCB peptidase (mitochondrial processing) beta
PNPT1 polyribonucleotide nucleotidyltransferase 1
POLDIP2 polymerase (DNA-directed), delta interacting protein 2
POLRMT polymerase (RNA) mitochondrial (DNA directed)
PRDX4 peroxiredoxin 4
PRDX5 peroxiredoxin 5
PTCD1 pentatricopeptide repeat domain 1
PTCD3 pentatricopeptide repeat domain 3
PUS1 pseudouridylate synthase 1
PUSL1 pseudouridylate synthase-like 1
PYCR2 pyrroline-5-carboxylate reductase family, member 2
RARS2 arginyl-tRNA synthetase 2, mitochondrial
RBFA ribosome binding factor A (putative)
RNMTL1 RNA methyltransferase like 1
RPUSD3 RNA pseudouridylate synthase domain containing 3
RPUSD4 RNA pseudouridylate synthase domain containing 4
SARS2 seryl-tRNA synthetase 2, mitochondrial
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
SFXN1 sideroflexin 1
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial)
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13
SLC25A18 solute carrier family 25 (glutamate carrier), member 18
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
SLIRP SRA stem-loop interacting RNA binding protein
SMC1A structural maintenance of chromosomes 1A
SOX2 SRY (sex determining region Y)-box 2
SSBP1 single-stranded DNA binding protein 1, mitochondrial
STOML2 stomatin (EPB72)-like 2
SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit
SUCLG1 succinate-CoA ligase, alpha subunit
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae)
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative)
TCEB1 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
TCEB2 transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)
TCF3 transcription factor 3
TEFM transcription elongation factor, mitochondrial
TFAM transcription factor A, mitochondrial
TFB1M transcription factor B1, mitochondrial
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TIMM21 translocase of inner mitochondrial membrane 21 homolog (yeast)
TMLHE trimethyllysine hydroxylase, epsilon
TOP1 topoisomerase (DNA) I
TP53 tumor protein p53
TRIP13 thyroid hormone receptor interactor 13
TRMT10C tRNA methyltransferase 10 homolog C (S. cerevisiae)
TRUB2 TruB pseudouridine (psi) synthase family member 2
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae)
TUBA1A tubulin, alpha 1a
TUFM Tu translation elongation factor, mitochondrial
UBC ubiquitin C
UBXN1 UBX domain protein 1
UQCRC1 ubiquinol-cytochrome c reductase core protein I
UQCRC2 ubiquinol-cytochrome c reductase core protein II
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
USP32 ubiquitin specific peptidase 32
USP6 ubiquitin specific peptidase 6
VARS2 valyl-tRNA synthetase 2, mitochondrial
VBP1 von Hippel-Lindau binding protein 1
VDAC1 voltage-dependent anion channel 1
VDAC3 voltage-dependent anion channel 3
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae)
WBSCR16 Williams-Beuren syndrome chromosome region 16
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial
YME1L1 YME1-like 1 ATPase
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta