| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | membrane-spanning 4-domains, subfamily A, member 2|The allergic response involves the binding of allergen to receptor-bound IgE followed by cell activation and the release of mediators responsible for the manifestations of allergy. The IgE-receptor, a tetramer composed of an alpha, beta, and 2 disulfide-linked gamma chains, is found on the surface of mast cells and basophils. This gene encodes the beta subunit of the high affinity IgE receptor which is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This family member is localized to 11q12, among a cluster of membrane-spanning 4A gene family members. Alternative splicing results in multiple transcript variants encoding distinct proteins. Additional transcript variants have been described but require experimental validation. [provided by RefSeq, Mar 2012] (NCBI Entrez Gene Database, 2206) |
| External Link | https://ncbi.nlm.nih.gov/gene/2206 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the MS4A2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HBB | hemoglobin, beta | 0.0177204 |
| MAP7 | microtubule-associated protein 7 | 0.017486 |
| LCN2 | lipocalin 2 | 0.0166443 |
| C3ORF14 | chromosome 3 open reading frame 14 | 0.0132656 |
| SPON1 | spondin 1, extracellular matrix protein | 0.0125869 |
| GCA | grancalcin, EF-hand calcium binding protein | 0.0120966 |
| HTRA1 | HtrA serine peptidase 1 | 0.0119921 |
| TXNDC9 | thioredoxin domain containing 9 | 0.0117056 |
| SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 | 0.0116765 |
| EVI2A | ecotropic viral integration site 2A | 0.0115239 |
| ARG1 | arginase 1 | 0.0113881 |
| RGS10 | regulator of G-protein signaling 10 | 0.0111692 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.0111277 |
| AOC1 | amine oxidase, copper containing 1 | 0.0110624 |
| DEFB1 | defensin, beta 1 | 0.0109741 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | 0.010917 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | 0.0108379 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 0.0107331 |
| GSTO1 | glutathione S-transferase omega 1 | 0.0105576 |
| SLC44A4 | solute carrier family 44, member 4 | 0.010553 |
| RPA3 | replication protein A3, 14kDa | 0.0105099 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.0105056 |
| CYBA | cytochrome b-245, alpha polypeptide | 0.0104993 |
| FGFR3 | fibroblast growth factor receptor 3 | 0.0103741 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | 0.0103183 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 0.010313 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 0.0103096 |
| ASRGL1 | asparaginase like 1 | 0.010286 |
| EMX2 | empty spiracles homeobox 2 | 0.0101831 |
| GUCY1B3 | guanylate cyclase 1, soluble, beta 3 | 0.0101049 |
| TSPAN1 | tetraspanin 1 | 0.00999355 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.00992073 |
| FAM171A1 | family with sequence similarity 171, member A1 | 0.00979348 |
| C6ORF48 | chromosome 6 open reading frame 48 | 0.0096743 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.00953908 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.00944809 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | 0.009378 |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) | 0.00934104 |
| CRYL1 | crystallin, lambda 1 | 0.00925506 |
| ARL3 | ADP-ribosylation factor-like 3 | 0.00921281 |
| KLK6 | kallikrein-related peptidase 6 | 0.00917836 |
| DCK | deoxycytidine kinase | 0.00914787 |
| RNASE6 | ribonuclease, RNase A family, k6 | 0.00913368 |
| CETN2 | centrin, EF-hand protein, 2 | 0.00913031 |
| C12ORF29 | chromosome 12 open reading frame 29 | 0.00910821 |
| CLDN10 | claudin 10 | 0.00898191 |
| WDR61 | WD repeat domain 61 | 0.00891259 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.00889891 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | 0.0088978 |
| FXYD2 | FXYD domain containing ion transport regulator 2 | 0.00889352 |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | 0.00878046 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | 0.00870456 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.00870291 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.00868718 |
| CSTA | cystatin A (stefin A) | 0.00864714 |
| LSM2 | LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.0086372 |
| MLF1 | myeloid leukemia factor 1 | 0.00860358 |
| EAF2 | ELL associated factor 2 | 0.0085917 |
| GRAMD1C | GRAM domain containing 1C | 0.00856957 |
| TCEAL1 | transcription elongation factor A (SII)-like 1 | 0.00855044 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | 0.00847437 |
| NME4 | NME/NM23 nucleoside diphosphate kinase 4 | 0.00837782 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | 0.00837428 |
| ECI2 | enoyl-CoA delta isomerase 2 | 0.00836786 |
| WFDC2 | WAP four-disulfide core domain 2 | 0.00836296 |
| ADIRF | adipogenesis regulatory factor | 0.00826376 |
| NME5 | NME/NM23 family member 5 | 0.00826175 |
| LXN | latexin | 0.00822316 |
| ICA1 | islet cell autoantigen 1, 69kDa | 0.00821821 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | 0.00819113 |
| SIRT5 | sirtuin 5 | 0.00818688 |
| TFF1 | trefoil factor 1 | 0.00816736 |
| SRGN | serglycin | 0.00816459 |
| SELL | selectin L | 0.00815488 |
| GJB1 | gap junction protein, beta 1, 32kDa | 0.00808358 |
| QPCT | glutaminyl-peptide cyclotransferase | 0.00803271 |
| ZFAND1 | zinc finger, AN1-type domain 1 | 0.00803183 |
| TXN | thioredoxin | 0.00802901 |
| CD200 | CD200 molecule | 0.00801894 |
| PLGRKT | plasminogen receptor, C-terminal lysine transmembrane protein | 0.00797685 |
| CLDN3 | claudin 3 | 0.00791736 |
| LPAR1 | lysophosphatidic acid receptor 1 | 0.00784492 |
| CMC2 | C-x(9)-C motif containing 2 | 0.00782462 |
| DDX11 | DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 | 0.00781691 |
| ABHD10 | abhydrolase domain containing 10 | 0.00780622 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | 0.00778774 |
| AMACR | alpha-methylacyl-CoA racemase | 0.00777071 |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 | 0.00776033 |
| RPL26L1 | ribosomal protein L26-like 1 | 0.00775366 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.00773089 |
| PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H | 0.00771547 |
| CRYM | crystallin, mu | 0.00769558 |
| ENPP4 | ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) | 0.00766642 |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor | 0.00766017 |
| CDK1 | cyclin-dependent kinase 1 | 0.0075856 |
| TRAPPC2L | trafficking protein particle complex 2-like | 0.00757653 |
| SH3YL1 | SH3 and SYLF domain containing 1 | 0.00756477 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 | 0.00753657 |
| PIR | pirin (iron-binding nuclear protein) | 0.00750458 |
| SHTN1 | shootin 1 | 0.00749609 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0074908 |
| COX7A2L | cytochrome c oxidase subunit VIIa polypeptide 2 like | 0.00749072 |
| SNRPG | small nuclear ribonucleoprotein polypeptide G | 0.00748768 |
| TNNT1 | troponin T type 1 (skeletal, slow) | 0.00746293 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | 0.00745589 |
| CPA3 | carboxypeptidase A3 (mast cell) | 0.00743735 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.00743382 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | 0.00742822 |
| RDH11 | retinol dehydrogenase 11 (all-trans/9-cis/11-cis) | 0.00742306 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 0.00741963 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | 0.00741648 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | 0.00739711 |
| GLUD1 | glutamate dehydrogenase 1 | 0.00737372 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | 0.00736803 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 | 0.00735755 |
| LACTB2 | lactamase, beta 2 | 0.00734952 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.00734347 |
| FAR2 | fatty acyl CoA reductase 2 | 0.00733174 |
| HIST3H2A | histone cluster 3, H2a | 0.00732521 |
| BTK | Bruton agammaglobulinemia tyrosine kinase | 0.00729189 |
| CEL | carboxyl ester lipase | 0.00728041 |
| AMD1 | adenosylmethionine decarboxylase 1 | 0.00727666 |
| ESR1 | estrogen receptor 1 | 0.00727491 |
| SLC17A3 | solute carrier family 17 (organic anion transporter), member 3 | 0.00723101 |
| TMEM38B | transmembrane protein 38B | 0.00720459 |
| ACSM3 | acyl-CoA synthetase medium-chain family member 3 | 0.00711768 |
| CD69 | CD69 molecule | 0.00710402 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.00709641 |
| PSME1 | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | 0.00707343 |
| S100A9 | S100 calcium binding protein A9 | 0.00706036 |
| IFITM2 | interferon induced transmembrane protein 2 | 0.00705833 |
| ELOVL6 | ELOVL fatty acid elongase 6 | 0.00705405 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.00704274 |
| ACP5 | acid phosphatase 5, tartrate resistant | 0.00699332 |
| VCAM1 | vascular cell adhesion molecule 1 | 0.00698597 |
| NIT2 | nitrilase family, member 2 | 0.0069803 |
| IRX5 | iroquois homeobox 5 | 0.00697821 |
| MAL | mal, T-cell differentiation protein | 0.00697566 |
| THAP10 | THAP domain containing 10 | 0.00697444 |
| EEF1E1 | eukaryotic translation elongation factor 1 epsilon 1 | 0.00696115 |
| RWDD1 | RWD domain containing 1 | 0.00693595 |
| RIDA | reactive intermediate imine deaminase A homolog | 0.00692239 |
| OCRL | oculocerebrorenal syndrome of Lowe | 0.0069181 |
| PFDN5 | prefoldin subunit 5 | 0.00691147 |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) | 0.00688477 |
| PRPF4 | pre-mRNA processing factor 4 | 0.00688347 |
| NDUFB1 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa | 0.00687538 |
| MMP8 | matrix metallopeptidase 8 | 0.00686846 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.00685438 |
| SLCO4C1 | solute carrier organic anion transporter family, member 4C1 | 0.00685207 |
| EAPP | E2F-associated phosphoprotein | 0.00684905 |
| PPA2 | pyrophosphatase (inorganic) 2 | 0.00684092 |
| CCNB1IP1 | cyclin B1 interacting protein 1, E3 ubiquitin protein ligase | 0.00683452 |
| HOXC6 | homeobox C6 | 0.00683047 |
| GBA3 | glucosidase, beta, acid 3 (gene/pseudogene) | 0.00683013 |
| OGDHL | oxoglutarate dehydrogenase-like | 0.00678713 |
| ARPC3 | actin related protein 2/3 complex, subunit 3, 21kDa | 0.0067865 |
| NSL1 | NSL1, MIS12 kinetochore complex component | 0.0067849 |
| RPL36 | ribosomal protein L36 | 0.00677305 |
| SKP1 | S-phase kinase-associated protein 1 | 0.00673589 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.00673125 |
| IFT27 | intraflagellar transport 27 | 0.00673055 |
| YPEL5 | yippee-like 5 (Drosophila) | 0.0067292 |
| CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 | 0.00672593 |
| HSD17B8 | hydroxysteroid (17-beta) dehydrogenase 8 | 0.00672557 |
| TNFSF13B | tumor necrosis factor (ligand) superfamily, member 13b | 0.00671515 |
| ZCCHC10 | zinc finger, CCHC domain containing 10 | 0.00671478 |
| HSBP1 | heat shock factor binding protein 1 | 0.00668654 |
| CENPU | centromere protein U | 0.00668022 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | 0.0066705 |
| OLFM1 | olfactomedin 1 | 0.00666466 |
| CYP4F3 | cytochrome P450, family 4, subfamily F, polypeptide 3 | 0.00665648 |
| MAP2K6 | mitogen-activated protein kinase kinase 6 | 0.0066406 |
| LSM6 | LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00663548 |
| CAMLG | calcium modulating ligand | 0.00662335 |
| ADD3 | adducin 3 (gamma) | 0.00659659 |
| ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide | 0.0065945 |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 | 0.00659346 |
| RELN | reelin | 0.00658301 |
| EPCAM | epithelial cell adhesion molecule | 0.00657784 |
| MSMO1 | methylsterol monooxygenase 1 | 0.00656869 |
| WASHC3 | WASH complex subunit 3 | 0.00656215 |
| CGRRF1 | cell growth regulator with ring finger domain 1 | 0.00656124 |
| MUC16 | mucin 16, cell surface associated | 0.00654877 |
| THBS1 | thrombospondin 1 | 0.00653017 |
| AKAP7 | A kinase (PRKA) anchor protein 7 | 0.00652905 |
| NEBL | nebulette | 0.00652323 |
| COMMD8 | COMM domain containing 8 | 0.00651 |
| CALML3 | calmodulin-like 3 | 0.00650465 |
| HSDL2 | hydroxysteroid dehydrogenase like 2 | 0.0065022 |
| COX7B | cytochrome c oxidase subunit VIIb | 0.00648426 |
| ATP5G2 | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) | 0.00648425 |
| S100A14 | S100 calcium binding protein A14 | 0.00647434 |
| DNASE1L3 | deoxyribonuclease I-like 3 | 0.00647012 |
| COG7 | component of oligomeric golgi complex 7 | 0.00646689 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.00646557 |
| CA12 | carbonic anhydrase XII | 0.00644147 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 | 0.00643949 |
| DACH1 | dachshund family transcription factor 1 | 0.00643769 |
| GTF2H5 | general transcription factor IIH, polypeptide 5 | 0.00643236 |
| LAGE3 | L antigen family, member 3 | 0.0064178 |
| BCL2A1 | BCL2-related protein A1 | 0.00641304 |
| CD48 | CD48 molecule | 0.0064065 |
| ZNHIT3 | zinc finger, HIT-type containing 3 | 0.00639254 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.00639167 |
| ADRA2A | adrenoceptor alpha 2A | 0.00639122 |
| MFAP3L | microfibrillar-associated protein 3-like | 0.00637429 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | 0.00635554 |
| CLC | Charcot-Leyden crystal galectin | 0.00634998 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 | 0.00633833 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | 0.00631324 |
| SORD | sorbitol dehydrogenase | 0.00630062 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | 0.00628764 |
| NPY | neuropeptide Y | 0.00628544 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.00624831 |
| KLK7 | kallikrein-related peptidase 7 | 0.00624628 |
| COPS4 | COP9 signalosome subunit 4 | 0.00622823 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00622694 |
| APOBEC3G | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G | 0.00620909 |
| RMI1 | RecQ mediated genome instability 1 | 0.00619461 |
| HBD | hemoglobin, delta | 0.00619391 |
| CCNG1 | cyclin G1 | 0.00616203 |
| GPR137B | G protein-coupled receptor 137B | 0.00615153 |
| MCUR1 | mitochondrial calcium uniporter regulator 1 | 0.00615031 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.00614968 |
| UPB1 | ureidopropionase, beta | 0.00614867 |
| CDC42 | cell division cycle 42 | 0.00614715 |
| KCNE4 | potassium channel, voltage gated subfamily E regulatory beta subunit 4 | 0.00614502 |
| LRP2 | low density lipoprotein receptor-related protein 2 | 0.00611477 |
| GRM3 | glutamate receptor, metabotropic 3 | 0.00610102 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | 0.0060914 |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | 0.00608317 |
| NFU1 | NFU1 iron-sulfur cluster scaffold | 0.00608237 |
| PAIP2B | poly(A) binding protein interacting protein 2B | 0.00604977 |
| HIGD1A | HIG1 hypoxia inducible domain family, member 1A | 0.00604383 |
| CYP4A11 | cytochrome P450, family 4, subfamily A, polypeptide 11 | 0.00603392 |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 | 0.00602937 |
| SDC1 | syndecan 1 | 0.00602073 |
| SMS | spermine synthase | 0.00601514 |
| PAH | phenylalanine hydroxylase | 0.006006 |
| GLO1 | glyoxalase I | 0.00600299 |
| FKBP3 | FK506 binding protein 3, 25kDa | 0.00599454 |
| PRIM1 | primase, DNA, polypeptide 1 (49kDa) | 0.0059945 |
| UROS | uroporphyrinogen III synthase | 0.00599029 |
| CPVL | carboxypeptidase, vitellogenic-like | 0.00598206 |
| METTL9 | methyltransferase like 9 | 0.00597728 |
| C1ORF54 | chromosome 1 open reading frame 54 | 0.00597274 |
| RPS25 | ribosomal protein S25 | 0.0059727 |
| PBLD | phenazine biosynthesis-like protein domain containing | 0.00597166 |
| RNF144A | ring finger protein 144A | 0.00596969 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MAGEA3 | melanoma antigen family A3 | -0.0212711 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.0171657 |
| MAGEA12 | melanoma antigen family A12 | -0.0140327 |
| CDC20 | cell division cycle 20 | -0.0136583 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | -0.0135735 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.0130872 |
| XIC | X chromosome inactivation center | -0.0127934 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0125579 |
| PMP22 | peripheral myelin protein 22 | -0.0118128 |
| TNS3 | tensin 3 | -0.0117175 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0115007 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | -0.0110986 |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta | -0.0107178 |
| MGP | matrix Gla protein | -0.0105476 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | -0.0105463 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.0105221 |
| FADS3 | fatty acid desaturase 3 | -0.0104935 |
| JMJD6 | jumonji domain containing 6 | -0.0104807 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0104213 |
| TNNC1 | troponin C type 1 (slow) | -0.0104025 |
| SYNM | synemin, intermediate filament protein | -0.0102449 |
| C3 | complement component 3 | -0.0102361 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0100169 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | -0.00989483 |
| BTG2 | BTG family, member 2 | -0.00984179 |
| MAGEA4 | melanoma antigen family A4 | -0.00978061 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.00977331 |
| POU2AF1 | POU class 2 associating factor 1 | -0.00975818 |
| FN1 | fibronectin 1 | -0.00959904 |
| LAMB3 | laminin, beta 3 | -0.00959761 |
| POSTN | periostin, osteoblast specific factor | -0.0095394 |
| BMP2 | bone morphogenetic protein 2 | -0.00953546 |
| HIST1H2BK | histone cluster 1, H2bk | -0.00951778 |
| CD163 | CD163 molecule | -0.00950867 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.00942051 |
| RFTN1 | raftlin, lipid raft linker 1 | -0.00939337 |
| IRS2 | insulin receptor substrate 2 | -0.0093866 |
| SLC38A1 | solute carrier family 38, member 1 | -0.00923689 |
| TAGLN | transgelin | -0.00920741 |
| HMOX1 | heme oxygenase 1 | -0.00919112 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | -0.00918215 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.0090786 |
| STIP1 | stress-induced phosphoprotein 1 | -0.00901337 |
| ZBTB35 | zinc finger and BTB domain containing 35 | -0.00893864 |
| AP3D1 | adaptor-related protein complex 3, delta 1 subunit | -0.00893816 |
| BMP4 | bone morphogenetic protein 4 | -0.00891663 |
| DUSP5 | dual specificity phosphatase 5 | -0.00872626 |
| PEG10 | paternally expressed 10 | -0.00872445 |
| TPM2 | tropomyosin 2 (beta) | -0.00870013 |
| CCDC86 | coiled-coil domain containing 86 | -0.00865665 |
| RBPMS | RNA binding protein with multiple splicing | -0.00864497 |
| C1S | complement component 1, s subcomponent | -0.00857523 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.00854895 |
| CFD | complement factor D (adipsin) | -0.00848609 |
| KRT7 | keratin 7, type II | -0.00844711 |
| TENT4A | terminal nucleotidyltransferase 4A | -0.0084246 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | -0.008311 |
| SDC4 | syndecan 4 | -0.00828261 |
| CTSA | cathepsin A | -0.00816429 |
| FOXO1 | forkhead box O1 | -0.00814919 |
| HSPA1A | heat shock 70kDa protein 1A | -0.00813647 |
| ENTPD4 | ectonucleoside triphosphate diphosphohydrolase 4 | -0.00808971 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | -0.00805798 |
| ITGA6 | integrin, alpha 6 | -0.0080536 |
| PKD1P1 | polycystic kidney disease 1 (autosomal dominant) pseudogene 1 | -0.00798559 |
| NPIPA1 | nuclear pore complex interacting protein family, member A1 | -0.00797741 |
| EMP1 | epithelial membrane protein 1 | -0.00795605 |
| MVP | major vault protein | -0.00794275 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.00789854 |
| CDK5RAP3 | CDK5 regulatory subunit associated protein 3 | -0.00788267 |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) | -0.00784414 |
| HACD1 | 3-hydroxyacyl-CoA dehydratase 1 | -0.00780976 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.00779312 |
| GBP2 | guanylate binding protein 2, interferon-inducible | -0.00776971 |
| IGF2R | insulin-like growth factor 2 receptor | -0.00769668 |
| HGS | hepatocyte growth factor-regulated tyrosine kinase substrate | -0.00767646 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric | -0.0076605 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.00764752 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.00763778 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.00763006 |
| FHL2 | four and a half LIM domains 2 | -0.00762748 |
| MAGEA1 | melanoma antigen family A1 | -0.00760241 |
| CTSE | cathepsin E | -0.00759409 |
| NXF1 | nuclear RNA export factor 1 | -0.00751517 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | -0.0075022 |
| SNX7 | sorting nexin 7 | -0.00748849 |
| IL32 | interleukin 32 | -0.0074865 |
| APOB | apolipoprotein B | -0.00745206 |
| PNN | pinin, desmosome associated protein | -0.0074307 |
| EXOC7 | exocyst complex component 7 | -0.00736151 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.00734003 |
| KRT17 | keratin 17, type I | -0.00732642 |
| ZNF91 | zinc finger protein 91 | -0.00731553 |
| CKM | creatine kinase, muscle | -0.0073085 |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 | -0.00730328 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 | -0.00729718 |
| PLXND1 | plexin D1 | -0.00729625 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.00726017 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | -0.00724779 |
| ACTN4 | actinin, alpha 4 | -0.00724668 |
| GRK5 | G protein-coupled receptor kinase 5 | -0.00719708 |
| RGS13 | regulator of G-protein signaling 13 | -0.00719675 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.00717831 |
| CCNL2 | cyclin L2 | -0.0071495 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.00714106 |
| MYH11 | myosin, heavy chain 11, smooth muscle | -0.00713667 |
| KCTD5 | potassium channel tetramerization domain containing 5 | -0.00712746 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -0.00710996 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.00710219 |
| C10ORF10 | chromosome 10 open reading frame 10 | -0.0070922 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.00707026 |
| RGS16 | regulator of G-protein signaling 16 | -0.00705932 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.00704871 |
| SFTPB | surfactant protein B | -0.00704369 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | -0.00704165 |
| BCHE | butyrylcholinesterase | -0.00702189 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | -0.00701015 |
| AKAP1 | A kinase (PRKA) anchor protein 1 | -0.00700887 |
| BCL6 | B-cell CLL/lymphoma 6 | -0.00700874 |
| RRAGA | Ras-related GTP binding A | -0.00700513 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.00700196 |
| NID1 | nidogen 1 | -0.006975 |
| CDIPT | CDP-diacylglycerol--inositol 3-phosphatidyltransferase | -0.00693062 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.00692756 |
| KRT18 | keratin 18, type I | -0.00692089 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.00690453 |
| ZBTB16 | zinc finger and BTB domain containing 16 | -0.00689844 |
| SNRNP70 | small nuclear ribonucleoprotein 70kDa (U1) | -0.00687751 |
| CUL1 | cullin 1 | -0.00685001 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | -0.00679702 |
| SSX1 | synovial sarcoma, X breakpoint 1 | -0.00679396 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | -0.00676289 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.00672569 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | -0.0066766 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | -0.00667327 |
| CCNA2 | cyclin A2 | -0.00666645 |
| MIR22HG | MIR22 host gene | -0.00665974 |
| SULT1A1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 | -0.00665368 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | -0.0066222 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -0.00661312 |
| COL15A1 | collagen, type XV, alpha 1 | -0.00660475 |
| AIM2 | absent in melanoma 2 | -0.00660139 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.00659747 |
| ARL14 | ADP-ribosylation factor-like 14 | -0.00658386 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.00656956 |
| NRCAM | neuronal cell adhesion molecule | -0.00656642 |
| CD70 | CD70 molecule | -0.00655614 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.00651753 |
| MSX1 | msh homeobox 1 | -0.00651706 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.00649044 |
| PLXNB2 | plexin B2 | -0.00648781 |
| LHFP | lipoma HMGIC fusion partner | -0.00646721 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.00644828 |
| WASHC5 | WASH complex subunit 5 | -0.00643679 |
| MLXIP | MLX interacting protein | -0.00643624 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0064342 |
| EGR1 | early growth response 1 | -0.00642482 |
| AHCYL1 | adenosylhomocysteinase-like 1 | -0.00642439 |
| RIN2 | Ras and Rab interactor 2 | -0.00640879 |
| PLOD3 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 | -0.00639329 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | -0.00636103 |
| MSL1 | male-specific lethal 1 homolog (Drosophila) | -0.00636091 |
| FRY | furry homolog (Drosophila) | -0.00635274 |
| MYL2 | myosin, light chain 2, regulatory, cardiac, slow | -0.00635035 |
| ACTA1 | actin, alpha 1, skeletal muscle | -0.00633708 |
| PMM2 | phosphomannomutase 2 | -0.00633654 |
| SEPTIN9 | septin 9 | -0.00632745 |
| LRP12 | low density lipoprotein receptor-related protein 12 | -0.00630334 |
| IRAK1 | interleukin-1 receptor-associated kinase 1 | -0.00628722 |
| NPC1 | Niemann-Pick disease, type C1 | -0.00628397 |
| TTN | titin | -0.00627914 |
| RRAD | Ras-related associated with diabetes | -0.00625816 |
| PILRB | paired immunoglobin-like type 2 receptor beta | -0.00625129 |
| SUSD6 | sushi domain containing 6 | -0.00623761 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.0062363 |
| NKTR | natural killer cell triggering receptor | -0.00623236 |
| ASPH | aspartate beta-hydroxylase | -0.00619378 |
| POLR3E | polymerase (RNA) III (DNA directed) polypeptide E (80kD) | -0.00618759 |
| UBE2I | ubiquitin-conjugating enzyme E2I | -0.00618297 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -0.00618007 |
| SLC35D1 | solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 | -0.00617617 |
| HELZ | helicase with zinc finger | -0.00617528 |
| BRD4 | bromodomain containing 4 | -0.00617371 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0061712 |
| PDE8B | phosphodiesterase 8B | -0.00616269 |
| FNBP4 | formin binding protein 4 | -0.00616216 |
| AMDHD2 | amidohydrolase domain containing 2 | -0.00615247 |
| OLFML2A | olfactomedin-like 2A | -0.00615108 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | -0.00614978 |
| PAM | peptidylglycine alpha-amidating monooxygenase | -0.00614777 |
| YBX3 | Y box binding protein 3 | -0.00613941 |
| WDR7 | WD repeat domain 7 | -0.00613247 |
| MAGEA11 | melanoma antigen family A11 | -0.00612915 |
| MAP3K7CL | MAP3K7 C-terminal like | -0.00612469 |
| ZNF512B | zinc finger protein 512B | -0.00610424 |
| CLU | clusterin | -0.00610233 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.00610114 |
| JAG1 | jagged 1 | -0.00608615 |
| TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 | -0.00607866 |
| ZBTB17 | zinc finger and BTB domain containing 17 | -0.00607257 |
| GABRE | gamma-aminobutyric acid (GABA) A receptor, epsilon | -0.00606078 |
| BCAP31 | B-cell receptor-associated protein 31 | -0.00605121 |
| EPHA2 | EPH receptor A2 | -0.00605109 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.00604826 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | -0.00604718 |
| TPTE | transmembrane phosphatase with tensin homology | -0.00604563 |
| A2M | alpha-2-macroglobulin | -0.00603985 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | -0.00603894 |
| RND3 | Rho family GTPase 3 | -0.00602699 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.00602648 |
| BSG | basigin (Ok blood group) | -0.00602628 |
| STC2 | stanniocalcin 2 | -0.00602222 |
| UXT | ubiquitously-expressed, prefoldin-like chaperone | -0.0060097 |
| CTSB | cathepsin B | -0.00600052 |
| MFAP5 | microfibrillar associated protein 5 | -0.00597981 |
| WDR1 | WD repeat domain 1 | -0.00597878 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.00597876 |
| FILIP1L | filamin A interacting protein 1-like | -0.00595791 |
| CAV2 | caveolin 2 | -0.00594849 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 | -0.00593232 |
| KANK2 | KN motif and ankyrin repeat domains 2 | -0.00593022 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | -0.00592794 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0059219 |
| KLHL41 | kelch-like family member 41 | -0.00591817 |
| ARHGEF18 | Rho/Rac guanine nucleotide exchange factor (GEF) 18 | -0.00591083 |
| STK25 | serine/threonine kinase 25 | -0.00590682 |
| UCKL1 | uridine-cytidine kinase 1-like 1 | -0.00589958 |
| GEM | GTP binding protein overexpressed in skeletal muscle | -0.00589114 |
| TNIP2 | TNFAIP3 interacting protein 2 | -0.00588636 |
| STX16 | syntaxin 16 | -0.00587157 |
| PPP2CB | protein phosphatase 2, catalytic subunit, beta isozyme | -0.00586113 |
| LPIN1 | lipin 1 | -0.00584948 |
| LYST | lysosomal trafficking regulator | -0.00584758 |
| DROSHA | drosha, ribonuclease type III | -0.00583582 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) | -0.00583338 |
| PIGG | phosphatidylinositol glycan anchor biosynthesis, class G | -0.00582559 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.00581209 |
| IGHMBP2 | immunoglobulin mu binding protein 2 | -0.00581127 |
| PI4KA | phosphatidylinositol 4-kinase, catalytic, alpha | -0.0058079 |
| MAN2C1 | mannosidase, alpha, class 2C, member 1 | -0.00580574 |
| ZNF395 | zinc finger protein 395 | -0.0057956 |
| ADIPOQ | adiponectin, C1Q and collagen domain containing | -0.00579221 |
| SEC14L1 | SEC14-like 1 (S. cerevisiae) | -0.00579201 |
| SIRT7 | sirtuin 7 | -0.005788 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | -0.00578077 |
| LRPAP1 | low density lipoprotein receptor-related protein associated protein 1 | -0.00576762 |
| SETD5 | SET domain containing 5 | -0.00576635 |
| MBD2 | methyl-CpG binding domain protein 2 | -0.0057524 |
| S100A2 | S100 calcium binding protein A2 | -0.00575143 |
