MSH2 Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description mutS homolog 2|This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012] (NCBI Entrez Gene Database, 4436)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/MORF_MSH2
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Genes

82 co-expressed genes for MSH2 from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
ACTL6A actin-like 6A
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
ALG8 ALG8, alpha-1,3-glucosyltransferase
ATP5J ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BUB3 BUB3 mitotic checkpoint protein
CCT5 chaperonin containing TCP1, subunit 5 (epsilon)
CHAF1A chromatin assembly factor 1, subunit A (p150)
CLNS1A chloride channel, nucleotide-sensitive, 1A
COPS5 COP9 signalosome subunit 5
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
DEK DEK proto-oncogene
DKC1 dyskeratosis congenita 1, dyskerin
EIF2B4 eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa
FANCI Fanconi anemia, complementation group I
FEN1 flap structure-specific endonuclease 1
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GINS1 GINS complex subunit 1 (Psf1 homolog)
GPN1 GPN-loop GTPase 1
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa
HAT1 histone acetyltransferase 1
HDAC2 histone deacetylase 2
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
IARS isoleucyl-tRNA synthetase
ICE1 interactor of little elongation complex ELL subunit 1
ILF2 interleukin enhancer binding factor 2
ITGB3BP integrin beta 3 binding protein (beta3-endonexin)
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KIAA0101 KIAA0101
LIG1 ligase I, DNA, ATP-dependent
LRPPRC leucine-rich pentatricopeptide repeat containing
MCM2 minichromosome maintenance complex component 2
MCM3 minichromosome maintenance complex component 3
MCM6 minichromosome maintenance complex component 6
MCM7 minichromosome maintenance complex component 7
METAP1 methionyl aminopeptidase 1
MLH1 mutL homolog 1
MRPS18B mitochondrial ribosomal protein S18B
MSH2 mutS homolog 2
MSH6 mutS homolog 6
NAE1 NEDD8 activating enzyme E1 subunit 1
NASP nuclear autoantigenic sperm protein (histone-binding)
NDC80 NDC80 kinetochore complex component
NUDC nudC nuclear distribution protein
NUP188 nucleoporin 188kDa
PARG poly (ADP-ribose) glycohydrolase
PCNA proliferating cell nuclear antigen
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae)
PRPSAP1 phosphoribosyl pyrophosphate synthetase-associated protein 1
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
RAD21 RAD21 homolog (S. pombe)
RAD51AP1 RAD51 associated protein 1
RANBP1 RAN binding protein 1
RFC4 replication factor C (activator 1) 4, 37kDa
RPA1 replication protein A1, 70kDa
RRM1 ribonucleotide reductase M1
RUVBL2 RuvB-like AAA ATPase 2
SART3 squamous cell carcinoma antigen recognized by T cells 3
SERBP1 SERPINE1 mRNA binding protein 1
SET SET nuclear proto-oncogene
SMC1A structural maintenance of chromosomes 1A
SMC4 structural maintenance of chromosomes 4
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5)
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa
SOD1 superoxide dismutase 1, soluble
SPCS2 signal peptidase complex subunit 2 homolog (S. cerevisiae)
SRSF1 serine/arginine-rich splicing factor 1
SSBP1 single-stranded DNA binding protein 1, mitochondrial
SSRP1 structure specific recognition protein 1
SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae)
TCERG1 transcription elongation regulator 1
TOP2A topoisomerase (DNA) II alpha 170kDa
TRRAP transformation/transcription domain-associated protein
U2SURP U2 snRNP-associated SURP domain containing
UNG uracil-DNA glycosylase
USP1 ubiquitin specific peptidase 1
XPO1 exportin 1
ZZZ3 zinc finger, ZZ-type containing 3