MSH3 Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description mutS homolog 3|The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer. This gene contains a polymorphic 9 bp tandem repeat sequence in the first exon. The repeat is present 6 times in the reference genome sequence and 3-7 repeats have been reported. Defects in this gene are a cause of susceptibility to endometrial cancer. [provided by RefSeq, Mar 2011] (NCBI Entrez Gene Database, 4437)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/MORF_MSH3
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Genes

245 co-expressed genes for MSH3 from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
ABCB10 ATP-binding cassette, sub-family B (MDR/TAP), member 10
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ADCY3 adenylate cyclase 3
AFF2 AF4/FMR2 family, member 2
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
AMOT angiomotin
AOC4P amine oxidase, copper containing 4, pseudogene
AQP5 aquaporin 5
AQP7 aquaporin 7
ARHGAP12 Rho GTPase activating protein 12
ARL3 ADP-ribosylation factor-like 3
ATF2 activating transcription factor 2
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
ATRX alpha thalassemia/mental retardation syndrome X-linked
ATXN3 ataxin 3
BARX2 BARX homeobox 2
BMP10 bone morphogenetic protein 10
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1
BPHL biphenyl hydrolase-like (serine hydrolase)
BRCA1 breast cancer 1, early onset
BRWD1 bromodomain and WD repeat domain containing 1
C1ORF216 chromosome 1 open reading frame 216
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CAMK4 calcium/calmodulin-dependent protein kinase IV
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCNF cyclin F
CDC73 cell division cycle 73
CDYL chromodomain protein, Y-like
CELA2B chymotrypsin-like elastase family, member 2B
CEP162 centrosomal protein 162kDa
CFH complement factor H
CHD9 chromodomain helicase DNA binding protein 9
CLOCK clock circadian regulator
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
CNKSR1 connector enhancer of kinase suppressor of Ras 1
COL19A1 collagen, type XIX, alpha 1
COLGALT2 collagen beta(1-O)galactosyltransferase 2
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
COQ7 coenzyme Q7 homolog, ubiquinone (yeast)
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CPB2 carboxypeptidase B2 (plasma)
CPEB3 cytoplasmic polyadenylation element binding protein 3
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa
CPZ carboxypeptidase Z
CRHR1 corticotropin releasing hormone receptor 1
CTRL chymotrypsin-like
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DGCR9 DiGeorge syndrome critical region gene 9 (non-protein coding)
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
DKK4 dickkopf WNT signaling pathway inhibitor 4
DMPK dystrophia myotonica-protein kinase
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16
DOCK1 dedicator of cytokinesis 1
DPT dermatopontin
ELAVL2 ELAV like neuron-specific RNA binding protein 2
EP400 E1A binding protein p400
EPHB2 EPH receptor B2
ERC1 ELKS/RAB6-interacting/CAST family member 1
ERCC4 excision repair cross-complementation group 4
ESR1 estrogen receptor 1
EXTL3 exostosin-like glycosyltransferase 3
FAM153B family with sequence similarity 153, member B
FGF18 fibroblast growth factor 18
FIG4 FIG4 phosphoinositide 5-phosphatase
FNTB farnesyltransferase, CAAX box, beta
FOSL1 FOS-like antigen 1
FOXD1 forkhead box D1
FPR2 formyl peptide receptor 2
FRY furry homolog (Drosophila)
FRYL FRY-like
FSHR follicle stimulating hormone receptor
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GJB5 gap junction protein, beta 5, 31.1kDa
GLE1 GLE1 RNA export mediator
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GNPAT glyceronephosphate O-acyltransferase
GPATCH8 G patch domain containing 8
GPR15 G protein-coupled receptor 15
GPR18 G protein-coupled receptor 18
GPR19 G protein-coupled receptor 19
GRIK5 glutamate receptor, ionotropic, kainate 5
GRIP2 glutamate receptor interacting protein 2
GTSE1 G-2 and S-phase expressed 1
HABP4 hyaluronan binding protein 4
HCRT hypocretin (orexin) neuropeptide precursor
HIC2 hypermethylated in cancer 2
HNF1A HNF1 homeobox A
HOXA11 homeobox A11
HOXD4 homeobox D4
HSPA13 heat shock protein 70kDa family, member 13
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
IFT27 intraflagellar transport 27
IGKV7-3 immunoglobulin kappa variable 7-3 (pseudogene)
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IL13 interleukin 13
IL16 interleukin 16
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
IQCK IQ motif containing K
IRF2 interferon regulatory factor 2
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3
JADE3 jade family PHD finger 3
JRK Jrk homolog (mouse)
KAZN kazrin, periplakin interacting protein
KHK ketohexokinase (fructokinase)
KIAA0586 KIAA0586
KLHDC10 kelch domain containing 10
KLHL18 kelch-like family member 18
KLRC4 killer cell lectin-like receptor subfamily C, member 4
KRR1 KRR1, small subunit (SSU) processome component, homolog (yeast)
KRT2 keratin 2, type II
KRT33A keratin 33A, type I
KRT86 keratin 86, type II
LEPROTL1 leptin receptor overlapping transcript-like 1
LPGAT1 lysophosphatidylglycerol acyltransferase 1
LRRC48 leucine rich repeat containing 48
LTBP4 latent transforming growth factor beta binding protein 4
LY9 lymphocyte antigen 9
MAGEA9 melanoma antigen family A9
MC5R melanocortin 5 receptor
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MFN1 mitofusin 1
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MON2 MON2 homolog (S. cerevisiae)
MSH3 mutS homolog 3
MSL3 male-specific lethal 3 homolog (Drosophila)
MUC8 mucin 8
NF1 neurofibromin 1
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NFX1 nuclear transcription factor, X-box binding 1
NFYB nuclear transcription factor Y, beta
NKRF NFKB repressing factor
NMT1 N-myristoyltransferase 1
NOS2 nitric oxide synthase 2, inducible
NPFF neuropeptide FF-amide peptide precursor
NR1I2 nuclear receptor subfamily 1, group I, member 2
NR2C1 nuclear receptor subfamily 2, group C, member 1
NRP2 neuropilin 2
NRTN neurturin
NTNG2 netrin G2
NXPE3 neurexophilin and PC-esterase domain family, member 3
OPLAH 5-oxoprolinase (ATP-hydrolysing)
OR2B6 olfactory receptor, family 2, subfamily B, member 6
P2RY10 purinergic receptor P2Y, G-protein coupled, 10
PAX7 paired box 7
PAX9 paired box 9
PAXIP1 PAX interacting (with transcription-activation domain) protein 1
PCF11 PCF11 cleavage and polyadenylation factor subunit
PDE6A phosphodiesterase 6A, cGMP-specific, rod, alpha
PGM3 phosphoglucomutase 3
PHF10 PHD finger protein 10
PHLDB1 pleckstrin homology-like domain, family B, member 1
PIAS2 protein inhibitor of activated STAT, 2
PIGF phosphatidylinositol glycan anchor biosynthesis, class F
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PITPNA phosphatidylinositol transfer protein, alpha
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
POFUT2 protein O-fucosyltransferase 2
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
POP4 processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae)
POU6F1 POU class 6 homeobox 1
POU6F2 POU class 6 homeobox 2
PPP1R12B protein phosphatase 1, regulatory subunit 12B
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A
PPP1R3D protein phosphatase 1, regulatory subunit 3D
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PPP5C protein phosphatase 5, catalytic subunit
PRIM2 primase, DNA, polypeptide 2 (58kDa)
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PSG1 pregnancy specific beta-1-glycoprotein 1
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
PTEN phosphatase and tensin homolog
PVR poliovirus receptor
RAD51D RAD51 paralog D
RAP1A RAP1A, member of RAS oncogene family
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit
RNF14 ring finger protein 14
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RREB1 ras responsive element binding protein 1
RUNX1 runt-related transcription factor 1
RUNX2 runt-related transcription factor 2
RXRG retinoid X receptor, gamma
SCAMP1 secretory carrier membrane protein 1
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
SIM2 single-minded family bHLH transcription factor 2
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC17A3 solute carrier family 17 (organic anion transporter), member 3
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1
SLC22A6 solute carrier family 22 (organic anion transporter), member 6
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1
SLC4A3 solute carrier family 4 (anion exchanger), member 3
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SMYD5 SMYD family member 5
SPA17 sperm autoantigenic protein 17
SPAG11B sperm associated antigen 11B
SPAST spastin
SPRED2 sprouty-related, EVH1 domain containing 2
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SULT4A1 sulfotransferase family 4A, member 1
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
SURF2 surfeit 2
SYNJ2 synaptojanin 2
SYT5 synaptotagmin V
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TBC1D22A TBC1 domain family, member 22A
TBX19 T-box 19
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2)
TMEM11 transmembrane protein 11
TMEM184B transmembrane protein 184B
TNIK TRAF2 and NCK interacting kinase
TRIM24 tripartite motif containing 24
TSSK2 testis-specific serine kinase 2
TTI1 TELO2 interacting protein 1
TTLL5 tubulin tyrosine ligase-like family member 5
UBE4B ubiquitination factor E4B
USP20 ubiquitin specific peptidase 20
USP46 ubiquitin specific peptidase 46
WBP4 WW domain binding protein 4
WIPF2 WAS/WASL interacting protein family, member 2
YAF2 YY1 associated factor 2
ZBTB14 zinc finger and BTB domain containing 14
ZBTB22 zinc finger and BTB domain containing 22
ZBTB40 zinc finger and BTB domain containing 40
ZNF133 zinc finger protein 133
ZNF134 zinc finger protein 134
ZNF157 zinc finger protein 157
ZNF266 zinc finger protein 266
ZNF33B zinc finger protein 33B
ZNF500 zinc finger protein 500
ZNF592 zinc finger protein 592
ZSCAN26 zinc finger and SCAN domain containing 26