MSK2 Gene Set

Dataset Kinase Library Serine Threonine Kinome Atlas
Category proteomics
Type kinase
Description ribosomal protein S6 kinase, 90kDa, polypeptide 4|This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including CREB1 and c-fos. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 8986)
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100 substrates of the kinase MSK2 from the Kinase Library Serine Threonine Kinome Atlas dataset.

Symbol Name Standardized Value
EHBP1L1 EH domain binding protein 1-like 1
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
NCOR1 nuclear receptor corepressor 1
LMO7 LIM domain 7
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
IER2 immediate early response 2
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
MIIP migration and invasion inhibitory protein
CD163L1 CD163 molecule-like 1
PLIN5 perilipin 5
SIK2 salt-inducible kinase 2
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1
MED14 mediator complex subunit 14
ORAI1 ORAI calcium release-activated calcium modulator 1
RPL34 ribosomal protein L34
ATF7 activating transcription factor 7
TRA2A transformer 2 alpha homolog (Drosophila)
IRS1 insulin receptor substrate 1
PDE3B phosphodiesterase 3B, cGMP-inhibited
RET ret proto-oncogene
SCAF1 SR-related CTD-associated factor 1
PLXNB1 plexin B1
ARHGAP11A Rho GTPase activating protein 11A
WNK1 WNK lysine deficient protein kinase 1
CTR9 CTR9, Paf1/RNA polymerase II complex component
AKAP12 A kinase (PRKA) anchor protein 12
ALKBH5 AlkB family member 5, RNA demethylase
RECQL4 RecQ protein-like 4
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
ZNF687 zinc finger protein 687
LTF lactotransferrin
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
RASD2 RASD family, member 2
ZNF609 zinc finger protein 609
TBC1D30 TBC1 domain family, member 30
CWC22 CWC22 spliceosome-associated protein
SASH1 SAM and SH3 domain containing 1
CCDC120 coiled-coil domain containing 120
PPAPDC3 phosphatidic acid phosphatase type 2 domain containing 3
MVD mevalonate (diphospho) decarboxylase
SOX9 SRY (sex determining region Y)-box 9
GOLGA3 golgin A3
LURAP1 leucine rich adaptor protein 1
SRSF2 serine/arginine-rich splicing factor 2
PCLO piccolo presynaptic cytomatrix protein
NEO1 neogenin 1
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
DEPDC5 DEP domain containing 5
PLEKHA5 pleckstrin homology domain containing, family A member 5
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SBSPON somatomedin B and thrombospondin, type 1 domain containing
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
LIMCH1 LIM and calponin homology domains 1
ANKRD33B ankyrin repeat domain 33B
ELMSAN1 ELM2 and Myb/SANT-like domain containing 1
POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD)
DVL2 dishevelled segment polarity protein 2
SALL3 spalt-like transcription factor 3
AQP2 aquaporin 2 (collecting duct)
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
DSP desmoplakin
FBXO41 F-box protein 41
INF2 inverted formin, FH2 and WH2 domain containing
GPATCH2 G patch domain containing 2
FKBP15 FK506 binding protein 15, 133kDa
GAS2L1 growth arrest-specific 2 like 1
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
CEP128 centrosomal protein 128kDa
KIAA0195 KIAA0195
USP6NL USP6 N-terminal like
PLCL1 phospholipase C-like 1
CDCA2 cell division cycle associated 2
ZNF337 zinc finger protein 337
RARG retinoic acid receptor, gamma
VANGL1 VANGL planar cell polarity protein 1
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2
ZFC3H1 zinc finger, C3H1-type containing
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
SETD2 SET domain containing 2
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
BEGAIN brain-enriched guanylate kinase-associated
MYO1F myosin IF
MYO1E myosin IE
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
UBE2O ubiquitin-conjugating enzyme E2O
KIF1C kinesin family member 1C
BRAF B-Raf proto-oncogene, serine/threonine kinase
PPP1R12C protein phosphatase 1, regulatory subunit 12C
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
FAM214B family with sequence similarity 214, member B
RSBN1 round spermatid basic protein 1
ARHGAP21 Rho GTPase activating protein 21
PKD2 polycystic kidney disease 2 (autosomal dominant)
MEPCE methylphosphate capping enzyme
CLK3 CDC-like kinase 3
USP34 ubiquitin specific peptidase 34
PYGB phosphorylase, glycogen; brain
PPP1R12A protein phosphatase 1, regulatory subunit 12A
TUSC2 tumor suppressor candidate 2