MSX1 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description msh homeobox 1|This gene encodes a member of the muscle segment homeobox gene family. The encoded protein functions as a transcriptional repressor during embryogenesis through interactions with components of the core transcription complex and other homeoproteins. It may also have roles in limb-pattern formation, craniofacial development, particularly odontogenesis, and tumor growth inhibition. Mutations in this gene, which was once known as homeobox 7, have been associated with nonsyndromic cleft lip with or without cleft palate 5, Witkop syndrome, Wolf-Hirschom syndrome, and autosomoal dominant hypodontia. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 4487)
External Link http://www.ncbi.nlm.nih.gov/gene/4487
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194 interacting proteins for MSX1 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACTR1A ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)
AES amino-terminal enhancer of split
ALYREF Aly/REF export factor
ANAPC10 anaphase promoting complex subunit 10
ANXA2 annexin A2
AP3B1 adaptor-related protein complex 3, beta 1 subunit
ARCN1 archain 1
ARL1 ADP-ribosylation factor-like 1
ARL8B ADP-ribosylation factor-like 8B
ASF1A anti-silencing function 1A histone chaperone
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila)
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1
BCAS2 breast carcinoma amplified sequence 2
BCL7C B-cell CLL/lymphoma 7C
BET1 Bet1 golgi vesicular membrane trafficking protein
C11ORF73 chromosome 11 open reading frame 73
C1ORF35 chromosome 1 open reading frame 35
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CAMSAP3 calmodulin regulated spectrin-associated protein family, member 3
CCDC59 coiled-coil domain containing 59
CDC23 cell division cycle 23
CDC42 cell division cycle 42
CDK2 cyclin-dependent kinase 2
CELF2 CUGBP, Elav-like family member 2
CEP55 centrosomal protein 55kDa
CFL1 cofilin 1 (non-muscle)
CHAF1A chromatin assembly factor 1, subunit A (p150)
CLASP1 cytoplasmic linker associated protein 1
CNOT12 CCR4-NOT transcription complex subunit 12
COA5 cytochrome c oxidase assembly factor 5
COL1A1 collagen, type I, alpha 1
COX5B cytochrome c oxidase subunit Vb
CPSF6 cleavage and polyadenylation specific factor 6, 68kDa
CREBBP CREB binding protein
CSE1L CSE1 chromosome segregation 1-like (yeast)
CTPS1 CTP synthase 1
CUL2 cullin 2
DAZAP1 DAZ associated protein 1
DES desmin
DGCR14 DiGeorge syndrome critical region gene 14
DLX2 distal-less homeobox 2
DLX5 distal-less homeobox 5
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9
DYNLL2 dynein, light chain, LC8-type 2
FIP1L1 factor interacting with PAPOLA and CPSF1
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
FLYWCH1 FLYWCH-type zinc finger 1
GATAD2A GATA zinc finger domain containing 2A
GCN1L1 GCN1 general control of amino-acid synthesis 1-like 1 (yeast)
GFAP glial fibrillary acidic protein
GIPC1 GIPC PDZ domain containing family, member 1
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GSTP1 glutathione S-transferase pi 1
GTSE1 G-2 and S-phase expressed 1
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HIST1H1D histone cluster 1, H1d
HMGB1 high mobility group box 1
HMMR hyaluronan-mediated motility receptor (RHAMM)
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HOXA9 homeobox A9
HOXB9 homeobox B9
HOXC8 homeobox C8
HOXC9 homeobox C9
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
IER3IP1 immediate early response 3 interacting protein 1
ING4 inhibitor of growth family, member 4
IPO5 importin 5
KLF16 Kruppel-like factor 16
LDHB lactate dehydrogenase B
LENG1 leukocyte receptor cluster (LRC) member 1
LHX2 LIM homeobox 2
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae)
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MAP7D2 MAP7 domain containing 2
MARCKS myristoylated alanine-rich protein kinase C substrate
MARK2 MAP/microtubule affinity-regulating kinase 2
MAZ MYC-associated zinc finger protein (purine-binding transcription factor)
MED19 mediator complex subunit 19
MED30 mediator complex subunit 30
MED8 mediator complex subunit 8
MKI67 marker of proliferation Ki-67
MSANTD4 Myb/SANT-like DNA-binding domain containing 4 with coiled-coils
MSX2 msh homeobox 2
MYH10 myosin, heavy chain 10, non-muscle
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle
MZT2B mitotic spindle organizing protein 2B
NACA nascent polypeptide-associated complex alpha subunit
NCOR1 nuclear receptor corepressor 1
NEFM neurofilament, medium polypeptide
NMNAT1 nicotinamide nucleotide adenylyltransferase 1
NUP155 nucleoporin 155kDa
NUP50 nucleoporin 50kDa
PAX3 paired box 3
PAX9 paired box 9
PDCD6 programmed cell death 6
PDCD7 programmed cell death 7
PIAS1 protein inhibitor of activated STAT, 1
PLS3 plastin 3
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
POU2F1 POU class 2 homeobox 1
PPIL1 peptidylprolyl isomerase (cyclophilin)-like 1
PRC1 protein regulator of cytokinesis 1
PRMT1 protein arginine methyltransferase 1
PRPF19 pre-mRNA processing factor 19
PRPF31 pre-mRNA processing factor 31
PTBP3 polypyrimidine tract binding protein 3
RAB10 RAB10, member RAS oncogene family
RAB1A RAB1A, member RAS oncogene family
RAB23 RAB23, member RAS oncogene family
RAB8B RAB8B, member RAS oncogene family
RABAC1 Rab acceptor 1 (prenylated)
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RAE1 ribonucleic acid export 1
RAN RAN, member RAS oncogene family
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
RBM39 RNA binding motif protein 39
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
RER1 retention in endoplasmic reticulum sorting receptor 1
RGS7 regulator of G-protein signaling 7
RNPC3 RNA-binding region (RNP1, RRM) containing 3
RPL11 ribosomal protein L11
RPL30 ribosomal protein L30
RPL35A ribosomal protein L35a
RPL38 ribosomal protein L38
RPRD1A regulation of nuclear pre-mRNA domain containing 1A
RPS10 ribosomal protein S10
RPS11 ribosomal protein S11
RPS14 ribosomal protein S14
RPS19BP1 ribosomal protein S19 binding protein 1
RPS27 ribosomal protein S27
RPS28 ribosomal protein S28
RPS4X ribosomal protein S4, X-linked
RPS7 ribosomal protein S7
SACK1D scaffolding CK1 anchoring protein D
SEC16A SEC16 homolog A (S. cerevisiae)
SEC24B SEC24 family member B
SEPT9 septin 9
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SF3B5 splicing factor 3b, subunit 5, 10kDa
SKA3 spindle and kinetochore associated complex subunit 3
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SNAP29 synaptosomal-associated protein, 29kDa
SNRNP35 small nuclear ribonucleoprotein 35kDa (U11/U12)
SNRPA small nuclear ribonucleoprotein polypeptide A
SNRPE small nuclear ribonucleoprotein polypeptide E
SNX3 sorting nexin 3
SP1 Sp1 transcription factor
SRI sorcin
SRP19 signal recognition particle 19kDa
SSBP1 single-stranded DNA binding protein 1, mitochondrial
SSRP1 structure specific recognition protein 1
SUMO1 small ubiquitin-like modifier 1
SUMO2 small ubiquitin-like modifier 2
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TARDBP TAR DNA binding protein
TBP TATA box binding protein
TERF2 telomeric repeat binding factor 2
TF transferrin
TFCP2 transcription factor CP2
THOC2 THO complex 2
TIA1 TIA1 cytotoxic granule-associated RNA binding protein
TIMM44 translocase of inner mitochondrial membrane 44 homolog (yeast)
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TLE2 transducin-like enhancer of split 2
TMED10 transmembrane emp24-like trafficking protein 10 (yeast)
TMPO thymopoietin
TNPO1 transportin 1
TNPO2 transportin 2
TNRC6C trinucleotide repeat containing 6C
TOPBP1 topoisomerase (DNA) II binding protein 1
TP53 tumor protein p53
TRIM33 tripartite motif containing 33
TRIP11 thyroid hormone receptor interactor 11
TUBA1A tubulin, alpha 1a
TUBA1C tubulin, alpha 1c
TUBB tubulin, beta class I
TXN thioredoxin
UBC ubiquitin C
UPF1 UPF1 regulator of nonsense transcripts homolog (yeast)
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast)
VAT1 vesicle amine transport 1
WDR41 WD repeat domain 41
WDR48 WD repeat domain 48
XPO1 exportin 1
XPO5 exportin 5
YIPF1 Yip1 domain family, member 1
YKT6 YKT6 v-SNARE homolog (S. cerevisiae)
ZMAT5 zinc finger, matrin-type 5
ZNF768 zinc finger protein 768