MTA1 Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description metastasis associated 1|This gene encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. Expression of this gene has been correlated with the metastatic potential of at least two types of carcinomas although it is also expressed in many normal tissues. The role it plays in metastasis is unclear. It was initially thought to be the 70kD component of a nucleosome remodeling deacetylase complex, NuRD, but it is more likely that this component is a different but very similar protein. These two proteins are so closely related, though, that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. The profile and activity of this gene product suggest that it is involved in regulating transcription and that this may be accomplished by chromatin remodeling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011] (NCBI Entrez Gene Database, 9112)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/MORF_MTA1
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Genes

102 co-expressed genes for MTA1 from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
ACTL6A actin-like 6A
AFG3L2 AFG3-like AAA ATPase 2
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
AP3S1 adaptor-related protein complex 3, sigma 1 subunit
ARF3 ADP-ribosylation factor 3
ARFGAP2 ADP-ribosylation factor GTPase activating protein 2
ATG12 autophagy related 12
BANF1 barrier to autointegration factor 1
BCAP31 B-cell receptor-associated protein 31
CANX calnexin
CENPB centromere protein B, 80kDa
CFDP1 craniofacial development protein 1
CNOT3 CCR4-NOT transcription complex, subunit 3
COIL coilin
COPS5 COP9 signalosome subunit 5
COX5A cytochrome c oxidase subunit Va
CS citrate synthase
CTDNEP1 CTD nuclear envelope phosphatase 1
CYC1 cytochrome c-1
DCTN2 dynactin 2 (p50)
DOCK3 dedicator of cytokinesis 3
DRG1 developmentally regulated GTP binding protein 1
ENSA endosulfine alpha
F8A1 coagulation factor VIII-associated 1
FAM120A family with sequence similarity 120A
FBXW11 F-box and WD repeat domain containing 11
FIBP fibroblast growth factor (acidic) intracellular binding protein
GGCT gamma-glutamylcyclotransferase
GPAA1 glycosylphosphatidylinositol anchor attachment 1
HDAC2 histone deacetylase 2
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B
ILF2 interleukin enhancer binding factor 2
ILVBL ilvB (bacterial acetolactate synthase)-like
KARS lysyl-tRNA synthetase
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
LYPLA1 lysophospholipase I
MAML1 mastermind-like 1 (Drosophila)
MAP2K2 mitogen-activated protein kinase kinase 2
METAP1 methionyl aminopeptidase 1
MRPL28 mitochondrial ribosomal protein L28
MRPL9 mitochondrial ribosomal protein L9
MRPS18B mitochondrial ribosomal protein S18B
MTA1 metastasis associated 1
MTCP1 mature T-cell proliferation 1
MTDH metadherin
NCBP2 nuclear cap binding protein subunit 2, 20kDa
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
NONO non-POU domain containing, octamer-binding
NSDHL NAD(P) dependent steroid dehydrogenase-like
NUP188 nucleoporin 188kDa
NUP62 nucleoporin 62kDa
PABPN1 poly(A) binding protein, nuclear 1
PDAP1 PDGFA associated protein 1
PHF3 PHD finger protein 3
PIGC phosphatidylinositol glycan anchor biosynthesis, class C
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G
PPP1R7 protein phosphatase 1, regulatory subunit 7
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
PUF60 poly-U binding splicing factor 60KDa
PWP1 PWP1 homolog (S. cerevisiae)
RAB6A RAB6A, member RAS oncogene family
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAD21 RAD21 homolog (S. pombe)
RAD23B RAD23 homolog B (S. cerevisiae)
RPA1 replication protein A1, 70kDa
SARS seryl-tRNA synthetase
SART3 squamous cell carcinoma antigen recognized by T cells 3
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
SERP1 stress-associated endoplasmic reticulum protein 1
SET SET nuclear proto-oncogene
SHFM1 split hand/foot malformation (ectrodactyly) type 1
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
SMG7 SMG7 nonsense mediated mRNA decay factor
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5)
SNRPA small nuclear ribonucleoprotein polypeptide A
SOD1 superoxide dismutase 1, soluble
SPCS2 signal peptidase complex subunit 2 homolog (S. cerevisiae)
SRP9 signal recognition particle 9kDa
SUMO1 small ubiquitin-like modifier 1
TCEA1 transcription elongation factor A (SII), 1
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1
TMBIM6 transmembrane BAX inhibitor motif containing 6
TMEM106C transmembrane protein 106C
TUFM Tu translation elongation factor, mitochondrial
TUG1 taurine up-regulated 1 (non-protein coding)
UBAP2L ubiquitin associated protein 2-like
XPO6 exportin 6
XPO7 exportin 7
XPOT exportin, tRNA
ZZZ3 zinc finger, ZZ-type containing 3