MTAP Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description methylthioadenosine phosphorylase|This gene encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage of both adenine and methionine. The encoded enzyme is deficient in many cancers because this gene and the tumor suppressor p16 gene are co-deleted. Multiple alternatively spliced transcript variants have been described for this gene, but their full-length natures remain unknown. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 4507)
External Link https://ncbi.nlm.nih.gov/gene/4507
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Genes

499 genes differentially expressed following the MTAP gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
CHP1 calcineurin-like EF-hand protein 1 0.0160985
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.0103454
HLA-DRA major histocompatibility complex, class II, DR alpha 0.00956308
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 0.00947927
C8ORF4 chromosome 8 open reading frame 4 0.00945057
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) 0.00928061
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) 0.00908075
PCNA proliferating cell nuclear antigen 0.00884049
HOXB2 homeobox B2 0.00875272
ACOT9 acyl-CoA thioesterase 9 0.00859354
PTP4A1 protein tyrosine phosphatase type IVA, member 1 0.00844252
TNC tenascin C 0.00841188
IRS2 insulin receptor substrate 2 0.00822582
CYTL1 cytokine-like 1 0.00819841
FZD6 frizzled class receptor 6 0.00808989
MTUS1 microtubule associated tumor suppressor 1 0.00800109
SLC26A2 solute carrier family 26 (anion exchanger), member 2 0.00794994
ZMYM2 zinc finger, MYM-type 2 0.00790225
CHPT1 choline phosphotransferase 1 0.00772668
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.00771376
CXCL13 chemokine (C-X-C motif) ligand 13 0.00757178
HSPA2 heat shock 70kDa protein 2 0.0075627
MCOLN1 mucolipin 1 0.00746355
GPER1 G protein-coupled estrogen receptor 1 0.00743931
JUP junction plakoglobin 0.00739788
SCD5 stearoyl-CoA desaturase 5 0.0073115
COL9A3 collagen, type IX, alpha 3 0.0072992
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 0.00729721
COL2A1 collagen, type II, alpha 1 0.00729311
AKAP12 A kinase (PRKA) anchor protein 12 0.00724007
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.00723336
GARS1 glycyl-tRNA synthetase 1 0.0072219
SFRP1 secreted frizzled-related protein 1 0.00722027
DLX2 distal-less homeobox 2 0.00721544
ZEB1 zinc finger E-box binding homeobox 1 0.00719499
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.00706329
GSN gelsolin 0.00693247
GULP1 GULP, engulfment adaptor PTB domain containing 1 0.00688468
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.00685949
TSPAN8 tetraspanin 8 0.00680807
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 0.00675093
MIA melanoma inhibitory activity 0.00672092
JAM3 junctional adhesion molecule 3 0.0066824
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 0.00663067
DCHS1 dachsous cadherin-related 1 0.00662977
MPP1 membrane protein, palmitoylated 1, 55kDa 0.00660721
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 0.00658644
NCOA4 nuclear receptor coactivator 4 0.00650167
GSTA4 glutathione S-transferase alpha 4 0.00648838
LAMA4 laminin, alpha 4 0.00647329
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 0.00647142
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 0.00643748
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.00640706
MAGEA10 melanoma antigen family A10 0.00638611
ACAA2 acetyl-CoA acyltransferase 2 0.00637178
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.00633752
HIST3H2A histone cluster 3, H2a 0.00632183
NMD3 NMD3 ribosome export adaptor 0.006312
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 0.00629325
EPHA3 EPH receptor A3 0.0062393
CRLF1 cytokine receptor-like factor 1 0.00622627
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2 0.00622022
ETHE1 ethylmalonic encephalopathy 1 0.00620301
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 0.00619475
MICU2 mitochondrial calcium uptake 2 0.00614992
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) 0.0061451
SATB2 SATB homeobox 2 0.00613758
MAGEA1 melanoma antigen family A1 0.00612147
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.00612084
TMX4 thioredoxin-related transmembrane protein 4 0.00610866
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 0.00604888
TACC2 transforming, acidic coiled-coil containing protein 2 0.00604621
PRAME preferentially expressed antigen in melanoma 0.00602956
SCRG1 stimulator of chondrogenesis 1 0.00601106
ATP9A ATPase, class II, type 9A 0.00601004
NME4 NME/NM23 nucleoside diphosphate kinase 4 0.00598855
RGS1 regulator of G-protein signaling 1 0.00598094
MAOB monoamine oxidase B 0.00596754
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 0.00593861
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 0.00591455
HBEGF heparin-binding EGF-like growth factor 0.00586478
CHGB chromogranin B 0.00585659
WWTR1 WW domain containing transcription regulator 1 0.00585593
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A 0.00583426
HPGDS hematopoietic prostaglandin D synthase 0.00583209
MAGEA4 melanoma antigen family A4 0.00582829
SHROOM2 shroom family member 2 0.00582589
ANPEP alanyl (membrane) aminopeptidase 0.00581225
ASS1 argininosuccinate synthase 1 0.00578884
POLR1D polymerase (RNA) I polypeptide D, 16kDa 0.00575213
VAMP8 vesicle-associated membrane protein 8 0.00574805
TMEM135 transmembrane protein 135 0.00573713
BMP2 bone morphogenetic protein 2 0.00573158
MGP matrix Gla protein 0.00572479
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 0.0057132
ACACA acetyl-CoA carboxylase alpha 0.00569031
COPS2 COP9 signalosome subunit 2 0.00568447
C1QA complement component 1, q subcomponent, A chain 0.00567653
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 0.00566855
S100B S100 calcium binding protein B 0.00566281
CRYL1 crystallin, lambda 1 0.0056174
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 0.00559575
CD177 CD177 molecule 0.00559449
AVPI1 arginine vasopressin-induced 1 0.00558372
CD14 CD14 molecule 0.00556886
SOBP sine oculis binding protein homolog (Drosophila) 0.00556277
LOC730101 uncharacterized LOC730101 0.00553536
ITGA6 integrin, alpha 6 0.00553001
SDC3 syndecan 3 0.00551735
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3 0.00551041
CD19 CD19 molecule 0.00550523
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A 0.00550177
NUPR1 nuclear protein, transcriptional regulator, 1 0.00548926
MAB21L2 mab-21-like 2 (C. elegans) 0.00548846
SCARB2 scavenger receptor class B, member 2 0.00547808
EGR3 early growth response 3 0.00545638
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 0.005456
SDC2 syndecan 2 0.00544848
SASH3 SAM and SH3 domain containing 3 0.00543102
EGR1 early growth response 1 0.00542473
DYNLL1 dynein, light chain, LC8-type 1 0.00542368
UBL3 ubiquitin-like 3 0.0054216
NBEA neurobeachin 0.00541683
BTK Bruton agammaglobulinemia tyrosine kinase 0.00540974
VSIG4 V-set and immunoglobulin domain containing 4 0.00539127
ANKRD10 ankyrin repeat domain 10 0.0053868
FBN2 fibrillin 2 0.00538087
VWA8 von Willebrand factor A domain containing 8 0.00537185
IL17RB interleukin 17 receptor B 0.00533515
FLRT3 fibronectin leucine rich transmembrane protein 3 0.0053254
HIST1H2BH histone cluster 1, H2bh 0.00530114
PLK1 polo-like kinase 1 0.00530032
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1) 0.0052997
GTF3C3 general transcription factor IIIC, polypeptide 3, 102kDa 0.00529786
RPS5 ribosomal protein S5 0.00529674
HOXB7 homeobox B7 0.00526006
ESD esterase D 0.00525366
ZMAT3 zinc finger, matrin-type 3 0.00524833
TCTN2 tectonic family member 2 0.00523514
SIGLEC15 sialic acid binding Ig-like lectin 15 0.00522262
IQCK IQ motif containing K 0.00521557
BIRC3 baculoviral IAP repeat containing 3 0.00521345
FURIN furin (paired basic amino acid cleaving enzyme) 0.00521003
KRT16 keratin 16, type I 0.00519582
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 0.00518526
CCNG2 cyclin G2 0.00518249
HBD hemoglobin, delta 0.00518029
CD79B CD79b molecule, immunoglobulin-associated beta 0.00517719
APOO apolipoprotein O 0.00516763
FGFR1 fibroblast growth factor receptor 1 0.00516096
RHBDF1 rhomboid 5 homolog 1 (Drosophila) 0.00515815
C14ORF132 chromosome 14 open reading frame 132 0.00515435
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) 0.00514397
RBBP7 retinoblastoma binding protein 7 0.00513276
SYNM synemin, intermediate filament protein 0.00512511
CD1A CD1a molecule 0.00512365
CRYAB crystallin, alpha B 0.00508852
PCLAF PCNA clamp associated factor 0.00508784
EPS8 epidermal growth factor receptor pathway substrate 8 0.00508635
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 0.00508304
FABP5 fatty acid binding protein 5 (psoriasis-associated) 0.00507109
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa 0.00507022
EGR2 early growth response 2 0.00506257
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) 0.00505687
PRDX4 peroxiredoxin 4 0.00505043
TSPAN1 tetraspanin 1 0.00504882
GYPC glycophorin C (Gerbich blood group) 0.00504435
POU2AF1 POU class 2 associating factor 1 0.00504366
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 0.00504035
TMEM176B transmembrane protein 176B 0.0050391
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 0.00502635
SMS spermine synthase 0.00502503
DLK1 delta-like 1 homolog (Drosophila) 0.00502159
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 0.00501815
CLEC2B C-type lectin domain family 2, member B 0.0050176
SMTN smoothelin 0.00501606
GDF15 growth differentiation factor 15 0.0049929
FADS3 fatty acid desaturase 3 0.00498633
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) 0.00497294
BAALC brain and acute leukemia, cytoplasmic 0.004972
BAG1 BCL2-associated athanogene 0.00496184
GLRX glutaredoxin (thioltransferase) 0.00496056
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 0.00495647
RRAS related RAS viral (r-ras) oncogene homolog 0.00495571
HIST1H2BK histone cluster 1, H2bk 0.00495394
WEE1 WEE1 G2 checkpoint kinase 0.00493918
CSTB cystatin B (stefin B) 0.00493748
SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12 0.0049372
EPB41L3 erythrocyte membrane protein band 4.1-like 3 0.00492729
CBS cystathionine-beta-synthase 0.00491604
LPAR6 lysophosphatidic acid receptor 6 0.00490958
SPRR2B small proline-rich protein 2B 0.00490724
MATN2 matrilin 2 0.00490566
STAB1 stabilin 1 0.00489608
SH3TC1 SH3 domain and tetratricopeptide repeats 1 0.00488641
MUC4 mucin 4, cell surface associated 0.00488616
DLEU1 deleted in lymphocytic leukemia 1 (non-protein coding) 0.00487468
SAP18 Sin3A-associated protein, 18kDa 0.00487068
PHB prohibitin 0.00486924
SOX10 SRY (sex determining region Y)-box 10 0.00485932
WDR61 WD repeat domain 61 0.00484385
TFRC transferrin receptor 0.00479138
CD164 CD164 molecule, sialomucin 0.00478801
TPD52L1 tumor protein D52-like 1 0.00478749
CD58 CD58 molecule 0.00478133
GPI glucose-6-phosphate isomerase 0.00475527
LPXN leupaxin 0.00475213
FOXD1 forkhead box D1 0.0047497
MOXD1 monooxygenase, DBH-like 1 0.00474705
TOM1L1 target of myb1 (chicken)-like 1 0.00473914
ZNF552 zinc finger protein 552 0.00473881
MEF2A myocyte enhancer factor 2A 0.00472666
ASNS asparagine synthetase (glutamine-hydrolyzing) 0.00472226
DUSP2 dual specificity phosphatase 2 0.00472067
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.00471245
GPATCH8 G patch domain containing 8 0.00471139
MT1G metallothionein 1G 0.00471122
FASTKD1 FAST kinase domains 1 0.00470857
OLA1 Obg-like ATPase 1 0.00469944
TOB1 transducer of ERBB2, 1 0.00469383
SELENOT selenoprotein T 0.00467813
FAM198B family with sequence similarity 198, member B 0.00467178
FRMD4B FERM domain containing 4B 0.00467045
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 0.00466425
AXIN1 axin 1 0.00465034
TRAF4 TNF receptor-associated factor 4 0.0046474
MPHOSPH8 M-phase phosphoprotein 8 0.0046474
NFE2L1 nuclear factor, erythroid 2-like 1 0.00464396
EMP1 epithelial membrane protein 1 0.00464268
CCDC28A coiled-coil domain containing 28A 0.00463917
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 0.00463633
COLEC12 collectin sub-family member 12 0.00462811
HLA-DMA major histocompatibility complex, class II, DM alpha 0.00462526
RANBP9 RAN binding protein 9 0.00462316
SLC44A4 solute carrier family 44, member 4 0.00461387
PROM1 prominin 1 0.00461141
SLC46A3 solute carrier family 46, member 3 0.00461054
KAZN kazrin, periplakin interacting protein 0.00460858
STK32B serine/threonine kinase 32B 0.00459453
ZNHIT1 zinc finger, HIT-type containing 1 0.0045874
TSC22D1 TSC22 domain family, member 1 0.00457971
PHOX2B paired-like homeobox 2b 0.00456497
RFK riboflavin kinase 0.00454743
HACD3 3-hydroxyacyl-CoA dehydratase 3 0.00454556
MARCHF5 membrane associated ring-CH-type finger 5 0.00453773
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2) 0.00453003
PLP1 proteolipid protein 1 0.00452992
FXYD2 FXYD domain containing ion transport regulator 2 0.00452475
CAVIN3 caveolae associated protein 3 0.00452056

decreased expression

Symbol Name Standardized Value
ALCAM activated leukocyte cell adhesion molecule -0.0160102
IKZF1 IKAROS family zinc finger 1 (Ikaros) -0.0148225
SCGB2A2 secretoglobin, family 2A, member 2 -0.0131188
EREG epiregulin -0.0118212
CASP2 caspase 2, apoptosis-related cysteine peptidase -0.0115647
KRT19 keratin 19, type I -0.0115503
CX3CR1 chemokine (C-X3-C motif) receptor 1 -0.0110288
SNAP25 synaptosomal-associated protein, 25kDa -0.0109752
PRR7 proline rich 7 (synaptic) -0.010825
EIF5A eukaryotic translation initiation factor 5A -0.0107169
THY1 Thy-1 cell surface antigen -0.0101832
SNAI2 snail family zinc finger 2 -0.00994782
GNG11 guanine nucleotide binding protein (G protein), gamma 11 -0.00979942
S100A8 S100 calcium binding protein A8 -0.00976151
PIP prolactin-induced protein -0.00955932
SLC39A8 solute carrier family 39 (zinc transporter), member 8 -0.00945107
CCNB1 cyclin B1 -0.00930459
IL7R interleukin 7 receptor -0.00922905
SCGB1D2 secretoglobin, family 1D, member 2 -0.00903078
DACH1 dachshund family transcription factor 1 -0.00895756
AREG amphiregulin -0.00887057
SLCO3A1 solute carrier organic anion transporter family, member 3A1 -0.0088013
NRGN neurogranin (protein kinase C substrate, RC3) -0.00868303
SRC SRC proto-oncogene, non-receptor tyrosine kinase -0.00856069
SDC1 syndecan 1 -0.0085498
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) -0.00850157
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 -0.00843873
KYNU kynureninase -0.00837028
ADI1 acireductone dioxygenase 1 -0.00833453
PLXNC1 plexin C1 -0.00831549
KRT7 keratin 7, type II -0.00824296
MEF2C myocyte enhancer factor 2C -0.00823557
CFD complement factor D (adipsin) -0.00816564
BEX1 brain expressed, X-linked 1 -0.00812042
NELL2 NEL-like 2 (chicken) -0.00801525
TACSTD2 tumor-associated calcium signal transducer 2 -0.0080051
DHCR24 24-dehydrocholesterol reductase -0.00794549
DGKZ diacylglycerol kinase, zeta -0.00792067
IL6R interleukin 6 receptor -0.00790296
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -0.00787653
OLFM1 olfactomedin 1 -0.00786798
G0S2 G0/G1 switch 2 -0.00765374
CXADR coxsackie virus and adenovirus receptor -0.00762494
ZBTB38 zinc finger and BTB domain containing 38 -0.00761297
LOXL1 lysyl oxidase-like 1 -0.00760059
SELL selectin L -0.00757484
VCL vinculin -0.00756205
PODXL podocalyxin-like -0.00738965
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 -0.00738861
MARCKS myristoylated alanine-rich protein kinase C substrate -0.00735676
TOMM34 translocase of outer mitochondrial membrane 34 -0.0073493
TPBG trophoblast glycoprotein -0.00732899
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 -0.00731449
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha -0.00722674
IRS1 insulin receptor substrate 1 -0.00718216
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 -0.0071713
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 -0.00712009
DHRS2 dehydrogenase/reductase (SDR family) member 2 -0.00711045
PF4 platelet factor 4 -0.00709687
MBL2 mannose-binding lectin (protein C) 2, soluble -0.00708968
OLFM4 olfactomedin 4 -0.00706499
STK10 serine/threonine kinase 10 -0.00703603
CES1 carboxylesterase 1 -0.00702601
ADAT1 adenosine deaminase, tRNA-specific 1 -0.00700376
HCRT hypocretin (orexin) neuropeptide precursor -0.00675026
TSPYL5 TSPY-like 5 -0.00666398
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 -0.00665519
TFF1 trefoil factor 1 -0.00651462
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) -0.00650898
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.00646644
CCDC85B coiled-coil domain containing 85B -0.00642227
HIP1 huntingtin interacting protein 1 -0.00637081
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -0.00636526
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 -0.00633711
NKG7 natural killer cell granule protein 7 -0.0063363
MAN2A1 mannosidase, alpha, class 2A, member 1 -0.00633465
FGFR3 fibroblast growth factor receptor 3 -0.00631327
MAP3K5 mitogen-activated protein kinase kinase kinase 5 -0.00630063
GNLY granulysin -0.00626919
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 -0.00626847
HNRNPL heterogeneous nuclear ribonucleoprotein L -0.00626167
PSRC1 proline/serine-rich coiled-coil 1 -0.00625135
GCA grancalcin, EF-hand calcium binding protein -0.00619861
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans) -0.00613187
TRIM44 tripartite motif containing 44 -0.0061198
VWF von Willebrand factor -0.00610462
PCP4 Purkinje cell protein 4 -0.00604076
SOX17 SRY (sex determining region Y)-box 17 -0.00603775
SH3YL1 SH3 and SYLF domain containing 1 -0.00603503
ITM2A integral membrane protein 2A -0.00601858
TYROBP TYRO protein tyrosine kinase binding protein -0.00598744
CD36 CD36 molecule (thrombospondin receptor) -0.0059766
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase -0.00597072
SLCO1B3 solute carrier organic anion transporter family, member 1B3 -0.0059658
HSPA1A heat shock 70kDa protein 1A -0.00593512
UBE2G2 ubiquitin-conjugating enzyme E2G 2 -0.00592638
ARHGAP32 Rho GTPase activating protein 32 -0.00590351
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha -0.00586893
DIAPH2 diaphanous-related formin 2 -0.0058486
SPARCL1 SPARC-like 1 (hevin) -0.00584538
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) -0.00584215
PCSK5 proprotein convertase subtilisin/kexin type 5 -0.00582472
NR2F1 nuclear receptor subfamily 2, group F, member 1 -0.00580966
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 -0.00580851
STEAP1 six transmembrane epithelial antigen of the prostate 1 -0.00580428
IFI16 interferon, gamma-inducible protein 16 -0.00580189
GBP1 guanylate binding protein 1, interferon-inducible -0.00580168
TACC1 transforming, acidic coiled-coil containing protein 1 -0.00579583
LGALS1 lectin, galactoside-binding, soluble, 1 -0.00579405
TPM4 tropomyosin 4 -0.00578283
BRD2 bromodomain containing 2 -0.00576754
CRYBG1 crystallin beta-gamma domain containing 1 -0.00575709
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1 -0.00573147
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -0.00572944
DDAH1 dimethylarginine dimethylaminohydrolase 1 -0.00570811
AZGP1 alpha-2-glycoprotein 1, zinc-binding -0.0057005
CYBB cytochrome b-245, beta polypeptide -0.00569218
PARP8 poly (ADP-ribose) polymerase family, member 8 -0.00569116
MFAP3L microfibrillar-associated protein 3-like -0.00568633
CD300A CD300a molecule -0.00567004
COQ8A coenzyme Q8A -0.00566831
TMBIM6 transmembrane BAX inhibitor motif containing 6 -0.00566641
GLIPR1 GLI pathogenesis-related 1 -0.00564191
KCTD12 potassium channel tetramerization domain containing 12 -0.00563504
LPCAT1 lysophosphatidylcholine acyltransferase 1 -0.0056334
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 -0.00563298
SPINK1 serine peptidase inhibitor, Kazal type 1 -0.00563273
TARP TCR gamma alternate reading frame protein -0.00562656
FABP4 fatty acid binding protein 4, adipocyte -0.00560304
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 -0.00557202
SEPTIN4 septin 4 -0.00554676
ACSM3 acyl-CoA synthetase medium-chain family member 3 -0.00550519
DPY19L1 dpy-19-like 1 (C. elegans) -0.00548885
CRISP3 cysteine-rich secretory protein 3 -0.00547022
SAMHD1 SAM domain and HD domain 1 -0.00546711
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 -0.00545705
SPARC secreted protein, acidic, cysteine-rich (osteonectin) -0.00544485
ITGA8 integrin, alpha 8 -0.00543758
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -0.00542811
LIMCH1 LIM and calponin homology domains 1 -0.00540641
MNDA myeloid cell nuclear differentiation antigen -0.00539803
THBS2 thrombospondin 2 -0.00539214
KDSR 3-ketodihydrosphingosine reductase -0.00538656
NDNF neuron-derived neurotrophic factor -0.0053805
S100A7 S100 calcium binding protein A7 -0.00534976
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 -0.0053486
ACTN1 actinin, alpha 1 -0.00532191
GLG1 golgi glycoprotein 1 -0.00529466
NIBAN1 niban apoptosis regulator 1 -0.00527494
PEA15 phosphoprotein enriched in astrocytes 15 -0.00526915
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 -0.0052638
SHCBP1 SHC SH2-domain binding protein 1 -0.00524635
COL10A1 collagen, type X, alpha 1 -0.00524223
LYZ lysozyme -0.00521459
PPIF peptidylprolyl isomerase F -0.00521254
USP22 ubiquitin specific peptidase 22 -0.00517612
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2 -0.00517313
SORL1 sortilin-related receptor, L(DLR class) A repeats containing -0.00516474
TAGLN transgelin -0.00515678
SELPLG selectin P ligand -0.00515275
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 -0.0051457
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein -0.0051409
GAS1 growth arrest-specific 1 -0.0051349
PLPP2 phospholipid phosphatase 2 -0.00513296
PRKACB protein kinase, cAMP-dependent, catalytic, beta -0.00512545
WT1 Wilms tumor 1 -0.00511496
GOLGA8H golgin A8 family, member H -0.00511087
PPP2R2B protein phosphatase 2, regulatory subunit B, beta -0.00510643
TFPI2 tissue factor pathway inhibitor 2 -0.0050989
AK4 adenylate kinase 4 -0.00508178
RNF167 ring finger protein 167 -0.00507856
TMEM45A transmembrane protein 45A -0.00506977
ABHD6 abhydrolase domain containing 6 -0.0050669
FYB1 FYN binding protein 1 -0.00505481
ZFPM2 zinc finger protein, FOG family member 2 -0.00504656
RDH14 retinol dehydrogenase 14 (all-trans/9-cis/11-cis) -0.00503117
WWC1 WW and C2 domain containing 1 -0.00502563
PPID peptidylprolyl isomerase D -0.00502055
BHLHE41 basic helix-loop-helix family, member e41 -0.00501415
C6ORF62 chromosome 6 open reading frame 62 -0.00501072
SCG5 secretogranin V -0.00499444
PRR5L proline rich 5 like -0.00498469
AP1M2 adaptor-related protein complex 1, mu 2 subunit -0.00495446
DIPK1A divergent protein kinase domain 1A -0.00494777
GATA6 GATA binding protein 6 -0.00494607
ESR1 estrogen receptor 1 -0.00494449
GFAP glial fibrillary acidic protein -0.00494435
PDGFRL platelet-derived growth factor receptor-like -0.00494047
KRT23 keratin 23, type I -0.00493854
HEG1 heart development protein with EGF-like domains 1 -0.00492799
FBXL5 F-box and leucine-rich repeat protein 5 -0.00491578
KLF2 Kruppel-like factor 2 -0.00489489
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha -0.00489203
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide -0.00488418
APOLD1 apolipoprotein L domain containing 1 -0.00487454
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 -0.00486412
FABP7 fatty acid binding protein 7, brain -0.00485395
KRT13 keratin 13, type I -0.00485166
TGFBI transforming growth factor, beta-induced, 68kDa -0.00484915
IL18 interleukin 18 -0.00483527
CUX2 cut-like homeobox 2 -0.00483395
ENAH enabled homolog (Drosophila) -0.00483233
NKX2-2 NK2 homeobox 2 -0.00483184
GMPR guanosine monophosphate reductase -0.00482443
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) -0.00480558
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX) -0.00479799
CCR2 chemokine (C-C motif) receptor 2 -0.00478295
IFI27 interferon, alpha-inducible protein 27 -0.00477711
GGCT gamma-glutamylcyclotransferase -0.00477643
F2R coagulation factor II (thrombin) receptor -0.00474439
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -0.00473909
SV2C synaptic vesicle glycoprotein 2C -0.00473812
GPSM2 G-protein signaling modulator 2 -0.00472953
MDM4 MDM4, p53 regulator -0.00472859
CTBP1 C-terminal binding protein 1 -0.00472797
TUBA4A tubulin, alpha 4a -0.00472547
LOC105375355 uroplakin-3b -0.00472367
PTGER4 prostaglandin E receptor 4 (subtype EP4) -0.00472104
KLRF1 killer cell lectin-like receptor subfamily F, member 1 -0.0047083
CLEC2D C-type lectin domain family 2, member D -0.00470001
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 -0.00469507
SLAMF7 SLAM family member 7 -0.00467938
UBA6 ubiquitin-like modifier activating enzyme 6 -0.00466649
LRRC15 leucine rich repeat containing 15 -0.00466338
COL6A2 collagen, type VI, alpha 2 -0.00465618
GPX2 glutathione peroxidase 2 -0.00465341
LY75 lymphocyte antigen 75 -0.00465214
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) -0.00464559
PADI2 peptidyl arginine deiminase, type II -0.00464467
SEPTIN7 septin 7 -0.00463244
RPA3 replication protein A3, 14kDa -0.00462963
KRT20 keratin 20, type I -0.00462804
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) -0.00460628
TTC19 tetratricopeptide repeat domain 19 -0.00460559
RAB25 RAB25, member RAS oncogene family -0.00459649
CYCS cytochrome c, somatic -0.00459369
FCN1 ficolin (collagen/fibrinogen domain containing) 1 -0.00458969
PFN1 profilin 1 -0.00458508
SRPX sushi-repeat containing protein, X-linked -0.00457967
PTGDR prostaglandin D2 receptor (DP) -0.004577
CAV1 caveolin 1, caveolae protein, 22kDa -0.00457053
MGAM maltase-glucoamylase -0.00455501
CCNA1 cyclin A1 -0.00454734
UBE3B ubiquitin protein ligase E3B -0.00454649
RBBP5 retinoblastoma binding protein 5 -0.0045462
CDH3 cadherin 3, type 1, P-cadherin (placental) -0.00454208
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 -0.00453945
PBX1 pre-B-cell leukemia homeobox 1 -0.00452744
COL6A3 collagen, type VI, alpha 3 -0.00452681
PDLIM3 PDZ and LIM domain 3 -0.00452099