MTF-1 Gene Set

Dataset MotifMap Predicted Transcription Factor Targets
Category genomics
Type transcription factor
Description metal-regulatory transcription factor 1|This gene encodes a transcription factor that induces expression of metallothioneins and other genes involved in metal homeostasis in response to heavy metals such as cadmium, zinc, copper, and silver. The protein is a nucleocytoplasmic shuttling protein that accumulates in the nucleus upon heavy metal exposure and binds to promoters containing a metal-responsive element (MRE). [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 4520)
Similar Terms
Downloads & Tools

Genes

3 target genes of the MTF-1 transcription factor predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.

Symbol Name
HMGA1 high mobility group AT-hook 1
MT4 metallothionein 4
PDE4A phosphodiesterase 4A, cAMP-specific