| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | methylenetetrahydrofolate reductase (NAD(P)H)|The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.[provided by RefSeq, Oct 2009] (NCBI Entrez Gene Database, 4524) |
| External Link | https://ncbi.nlm.nih.gov/gene/4524 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the MTHFR gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PCNA | proliferating cell nuclear antigen | 0.0215562 |
| TXNDC9 | thioredoxin domain containing 9 | 0.0180899 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0114152 |
| KRT7 | keratin 7, type II | 0.011051 |
| LTF | lactotransferrin | 0.0103305 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | 0.0101189 |
| LYZ | lysozyme | 0.0100183 |
| PDGFC | platelet derived growth factor C | 0.00998759 |
| MPO | myeloperoxidase | 0.00969349 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | 0.00965342 |
| PCLAF | PCNA clamp associated factor | 0.0091083 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.0090005 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | 0.00893631 |
| ELANE | elastase, neutrophil expressed | 0.00850704 |
| SMYD2 | SET and MYND domain containing 2 | 0.0083307 |
| TMEM14B | transmembrane protein 14B | 0.00832854 |
| S100A8 | S100 calcium binding protein A8 | 0.00832217 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.00827288 |
| TPD52L1 | tumor protein D52-like 1 | 0.00826492 |
| DACH1 | dachshund family transcription factor 1 | 0.0082213 |
| EMX2 | empty spiracles homeobox 2 | 0.00820038 |
| S100A9 | S100 calcium binding protein A9 | 0.00816863 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.00813582 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | 0.00808254 |
| ACAA1 | acetyl-CoA acyltransferase 1 | 0.00804206 |
| APMAP | adipocyte plasma membrane associated protein | 0.00795703 |
| CPA3 | carboxypeptidase A3 (mast cell) | 0.00795627 |
| SNRPG | small nuclear ribonucleoprotein polypeptide G | 0.00788069 |
| LBH | limb bud and heart development | 0.00783365 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | 0.0077692 |
| C3ORF14 | chromosome 3 open reading frame 14 | 0.00771487 |
| TOB1 | transducer of ERBB2, 1 | 0.00768094 |
| PFDN4 | prefoldin subunit 4 | 0.00762956 |
| KRT19 | keratin 19, type I | 0.00757015 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.00756924 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | 0.00754566 |
| NDNF | neuron-derived neurotrophic factor | 0.00751017 |
| EPHA4 | EPH receptor A4 | 0.00748644 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.00741003 |
| CST7 | cystatin F (leukocystatin) | 0.00740121 |
| MSMB | microseminoprotein, beta- | 0.00733668 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | 0.00728897 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 0.00727177 |
| CENPU | centromere protein U | 0.00711533 |
| PENK | proenkephalin | 0.0070381 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 0.00701014 |
| ORC4 | origin recognition complex, subunit 4 | 0.00697536 |
| NTS | neurotensin | 0.00687167 |
| SRGN | serglycin | 0.00686762 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 | 0.00685336 |
| PIP | prolactin-induced protein | 0.00685068 |
| HSPB11 | heat shock protein family B (small), member 11 | 0.00684109 |
| PKP4 | plakophilin 4 | 0.0068217 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.00679042 |
| HIST1H2BD | histone cluster 1, H2bd | 0.00675203 |
| TYMS | thymidylate synthetase | 0.00671303 |
| CRYM | crystallin, mu | 0.00662965 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.00659406 |
| MLF1 | myeloid leukemia factor 1 | 0.00657039 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.00655197 |
| DDRGK1 | DDRGK domain containing 1 | 0.00654828 |
| ITGA4 | integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) | 0.00653726 |
| UPK1B | uroplakin 1B | 0.00652965 |
| TIMM8B | translocase of inner mitochondrial membrane 8 homolog B (yeast) | 0.00652593 |
| DEFA4 | defensin, alpha 4, corticostatin | 0.00652529 |
| SFTPD | surfactant protein D | 0.0065151 |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) | 0.00647793 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | 0.00647345 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | 0.00642186 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | 0.00638954 |
| EEF1E1 | eukaryotic translation elongation factor 1 epsilon 1 | 0.00633742 |
| KRT23 | keratin 23, type I | 0.00632959 |
| REV1 | REV1, polymerase (DNA directed) | 0.00629011 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | 0.0062875 |
| IDH3B | isocitrate dehydrogenase 3 (NAD+) beta | 0.00627601 |
| HIST1H2AE | histone cluster 1, H2ae | 0.00626193 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.00622868 |
| NME4 | NME/NM23 nucleoside diphosphate kinase 4 | 0.00621212 |
| SNRPB2 | small nuclear ribonucleoprotein polypeptide B | 0.00619433 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | 0.00618338 |
| PANK2 | pantothenate kinase 2 | 0.00617251 |
| KYAT3 | kynurenine aminotransferase 3 | 0.00616404 |
| ERGIC3 | ERGIC and golgi 3 | 0.00615263 |
| RAB32 | RAB32, member RAS oncogene family | 0.00614633 |
| CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 | 0.00614171 |
| RPS27L | ribosomal protein S27-like | 0.00613144 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | 0.00610385 |
| NIBAN1 | niban apoptosis regulator 1 | 0.00609584 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.00609106 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.00604138 |
| GPNMB | glycoprotein (transmembrane) nmb | 0.00603326 |
| SH3YL1 | SH3 and SYLF domain containing 1 | 0.00602334 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 0.00601533 |
| PTS | 6-pyruvoyltetrahydropterin synthase | 0.00601104 |
| CDS2 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 | 0.00597632 |
| MLPH | melanophilin | 0.00596235 |
| ITPA | inosine triphosphatase (nucleoside triphosphate pyrophosphatase) | 0.00594709 |
| NNMT | nicotinamide N-methyltransferase | 0.00593701 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | 0.00590708 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.00590059 |
| MCUR1 | mitochondrial calcium uniporter regulator 1 | 0.00587851 |
| MGAM | maltase-glucoamylase | 0.00585686 |
| TSPOAP1 | TSPO associated protein 1 | 0.00581831 |
| ZWINT | ZW10 interacting kinetochore protein | 0.00573547 |
| DEPTOR | DEP domain containing MTOR-interacting protein | 0.00570986 |
| ZNF443 | zinc finger protein 443 | 0.00570964 |
| TMEM50B | transmembrane protein 50B | 0.00569336 |
| TASP1 | taspase, threonine aspartase, 1 | 0.00568292 |
| PAGE4 | P antigen family, member 4 (prostate associated) | 0.00568169 |
| SFTPA2 | surfactant protein A2 | 0.00567161 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | 0.0056484 |
| TMEM131 | transmembrane protein 131 | 0.00562731 |
| TGM2 | transglutaminase 2 | 0.00561988 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | 0.00561345 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.00557134 |
| CAMP | cathelicidin antimicrobial peptide | 0.00557059 |
| PFDN5 | prefoldin subunit 5 | 0.00555522 |
| MRPL40 | mitochondrial ribosomal protein L40 | 0.00555299 |
| NSFL1C | NSFL1 (p97) cofactor (p47) | 0.00551091 |
| HCRT | hypocretin (orexin) neuropeptide precursor | 0.00550534 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.0055 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.00548441 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | 0.00548396 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | 0.00547095 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.00545006 |
| BDH2 | 3-hydroxybutyrate dehydrogenase, type 2 | 0.00544769 |
| TPRKB | TP53RK binding protein | 0.00542353 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.00541874 |
| SPRY2 | sprouty homolog 2 (Drosophila) | 0.00541098 |
| CD63 | CD63 molecule | 0.00541043 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | 0.00538223 |
| GSS | glutathione synthetase | 0.00538164 |
| ATIC | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase | 0.00537019 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.00536843 |
| UNC50 | unc-50 homolog (C. elegans) | 0.0053663 |
| COMT | catechol-O-methyltransferase | 0.00536322 |
| NDUFB2 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa | 0.00535814 |
| BCHE | butyrylcholinesterase | 0.0053554 |
| EPCAM | epithelial cell adhesion molecule | 0.00535365 |
| MCM6 | minichromosome maintenance complex component 6 | 0.00535284 |
| MELK | maternal embryonic leucine zipper kinase | 0.00534827 |
| UFD1 | ubiquitin recognition factor in ER associated degradation 1 | 0.00531255 |
| TRAPPC4 | trafficking protein particle complex 4 | 0.00531127 |
| HP | haptoglobin | 0.00529572 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.00529104 |
| CLU | clusterin | 0.00528062 |
| RAB29 | RAB29, member RAS oncogene family | 0.00527164 |
| COLGALT2 | collagen beta(1-O)galactosyltransferase 2 | 0.00527108 |
| THYN1 | thymocyte nuclear protein 1 | 0.00526284 |
| SEC61G | Sec61 gamma subunit | 0.00526279 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.00526125 |
| MCUB | mitochondrial calcium uniporter dominant negative subunit beta | 0.00525524 |
| MNDA | myeloid cell nuclear differentiation antigen | 0.00524705 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 0.00524205 |
| DHCR24 | 24-dehydrocholesterol reductase | 0.00521794 |
| LY6G6D | lymphocyte antigen 6 complex, locus G6D | 0.00520741 |
| YME1L1 | YME1-like 1 ATPase | 0.00517779 |
| ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide | 0.00516845 |
| PSMA6 | proteasome (prosome, macropain) subunit, alpha type, 6 | 0.00515527 |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) | 0.0051501 |
| SFTPC | surfactant protein C | 0.00514728 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.00512764 |
| PXDC1 | PX domain containing 1 | 0.00512664 |
| TPSAB1 | tryptase alpha/beta 1 | 0.00509037 |
| TSPAN13 | tetraspanin 13 | 0.00507715 |
| MT1M | metallothionein 1M | 0.00506555 |
| UTP14A | UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) | 0.00506075 |
| KIAA0100 | KIAA0100 | 0.00505576 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.00505336 |
| GPM6A | glycoprotein M6A | 0.00503026 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | 0.00502751 |
| CYB5A | cytochrome b5 type A (microsomal) | 0.00502626 |
| GALNT11 | polypeptide N-acetylgalactosaminyltransferase 11 | 0.00502306 |
| HOMER2 | homer scaffolding protein 2 | 0.0050138 |
| TGIF1 | TGFB-induced factor homeobox 1 | 0.00501222 |
| RRM2 | ribonucleotide reductase M2 | 0.00501139 |
| WWOX | WW domain containing oxidoreductase | 0.00500101 |
| H2AX | H2A.X variant histone | 0.00499941 |
| PAX5 | paired box 5 | 0.00499917 |
| GREM1 | gremlin 1, DAN family BMP antagonist | 0.00499248 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | 0.00498634 |
| PRTN3 | proteinase 3 | 0.00498589 |
| TSPAN4 | tetraspanin 4 | 0.0049828 |
| CHMP4A | charged multivesicular body protein 4A | 0.00498155 |
| PON2 | paraoxonase 2 | 0.00496593 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | 0.00495892 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | 0.00493347 |
| SLC38A2 | solute carrier family 38, member 2 | 0.00492581 |
| TESC | tescalcin | 0.0049236 |
| PREPL | prolyl endopeptidase-like | 0.00491229 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 0.00490979 |
| TMEM87A | transmembrane protein 87A | 0.00490817 |
| FAHD2A | fumarylacetoacetate hydrolase domain containing 2A | 0.00488868 |
| SOCS2 | suppressor of cytokine signaling 2 | 0.00488571 |
| NOP56 | NOP56 ribonucleoprotein | 0.00488507 |
| EPHA3 | EPH receptor A3 | 0.00488245 |
| HGF | hepatocyte growth factor (hepapoietin A; scatter factor) | 0.00488209 |
| SNX3 | sorting nexin 3 | 0.00487831 |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 | 0.00487209 |
| FOLR1 | folate receptor 1 (adult) | 0.00486044 |
| NPRL2 | nitrogen permease regulator-like 2 (S. cerevisiae) | 0.00485964 |
| CPB1 | carboxypeptidase B1 (tissue) | 0.00485303 |
| BUD31 | BUD31 homolog (S. cerevisiae) | 0.00483698 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.00483355 |
| S100P | S100 calcium binding protein P | 0.0048288 |
| ABCA3 | ATP-binding cassette, sub-family A (ABC1), member 3 | 0.00481046 |
| CHI3L2 | chitinase 3-like 2 | 0.00480893 |
| ZNHIT3 | zinc finger, HIT-type containing 3 | 0.00480403 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.00479938 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) | 0.004793 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.00479258 |
| SOSTDC1 | sclerostin domain containing 1 | 0.00479009 |
| RNASE3 | ribonuclease, RNase A family, 3 | 0.00478261 |
| BPI | bactericidal/permeability-increasing protein | 0.00477833 |
| ATP6V0E2 | ATPase, H+ transporting V0 subunit e2 | 0.00477287 |
| CNPY3 | canopy FGF signaling regulator 3 | 0.00476188 |
| WT1 | Wilms tumor 1 | 0.00475141 |
| HBD | hemoglobin, delta | 0.00473408 |
| SESN1 | sestrin 1 | 0.00473015 |
| VPS16 | vacuolar protein sorting 16 homolog (S. cerevisiae) | 0.00472479 |
| TCEAL1 | transcription elongation factor A (SII)-like 1 | 0.00472029 |
| MOB4 | MOB family member 4, phocein | 0.00471718 |
| ZNF239 | zinc finger protein 239 | 0.00470372 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | 0.00470287 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | 0.00467861 |
| CSF3R | colony stimulating factor 3 receptor (granulocyte) | 0.00467711 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.00467151 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | 0.00467106 |
| DARS1 | aspartyl-tRNA synthetase 1 | 0.00466912 |
| EMID1 | EMI domain containing 1 | 0.00466257 |
| INHBA | inhibin, beta A | 0.0046622 |
| PARP2 | poly (ADP-ribose) polymerase 2 | 0.00465585 |
| XCL1 | chemokine (C motif) ligand 1 | 0.00465567 |
| S100A12 | S100 calcium binding protein A12 | 0.00465525 |
| FGF2 | fibroblast growth factor 2 (basic) | 0.00465423 |
| KRTAP1-1 | keratin associated protein 1-1 | 0.0046439 |
| MAGEA3 | melanoma antigen family A3 | 0.0046336 |
| LAMTOR3 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 | 0.0046304 |
| SATB2 | SATB homeobox 2 | 0.00462175 |
| ESR1 | estrogen receptor 1 | 0.00460077 |
| OLFML3 | olfactomedin-like 3 | 0.00459908 |
| FAM107A | family with sequence similarity 107, member A | 0.00458949 |
| OVGP1 | oviductal glycoprotein 1, 120kDa | 0.00458571 |
| FBXO21 | F-box protein 21 | 0.00457814 |
| MCM5 | minichromosome maintenance complex component 5 | 0.0045777 |
| HDC | histidine decarboxylase | 0.00457572 |
| NUP58 | nucleoporin 58 | 0.00457016 |
| FBN2 | fibrillin 2 | 0.00456444 |
| MMP8 | matrix metallopeptidase 8 | 0.00455794 |
| SULF1 | sulfatase 1 | 0.00455664 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | -0.0137517 |
| RTN2 | reticulon 2 | -0.013271 |
| KRT14 | keratin 14, type I | -0.0123609 |
| NID1 | nidogen 1 | -0.0119964 |
| CD93 | CD93 molecule | -0.011456 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.0109292 |
| ITGA6 | integrin, alpha 6 | -0.0108538 |
| XPO7 | exportin 7 | -0.0107451 |
| OLFML2A | olfactomedin-like 2A | -0.0104975 |
| MAL | mal, T-cell differentiation protein | -0.0104926 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | -0.0103053 |
| SIRT3 | sirtuin 3 | -0.0102289 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.00994637 |
| KLK10 | kallikrein-related peptidase 10 | -0.00994108 |
| JCHAIN | joining chain of multimeric IgA and IgM | -0.00993568 |
| PDGFD | platelet derived growth factor D | -0.00988392 |
| TPD52 | tumor protein D52 | -0.00975701 |
| PEG10 | paternally expressed 10 | -0.00961641 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | -0.00954644 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.00942929 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | -0.0094264 |
| PI3 | peptidase inhibitor 3, skin-derived | -0.00940502 |
| TNNT1 | troponin T type 1 (skeletal, slow) | -0.00929085 |
| H1-10 | H1.10 linker histone | -0.00926171 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | -0.0092268 |
| LAMB1 | laminin, beta 1 | -0.00886947 |
| FGFBP1 | fibroblast growth factor binding protein 1 | -0.0088193 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 | -0.00869296 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.00861013 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | -0.00837286 |
| RGS5 | regulator of G-protein signaling 5 | -0.00837211 |
| GAL | galanin/GMAP prepropeptide | -0.00833704 |
| H1-0 | H1.0 linker histone | -0.00832519 |
| C10ORF10 | chromosome 10 open reading frame 10 | -0.00829737 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | -0.00828721 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -0.00824749 |
| KLK11 | kallikrein-related peptidase 11 | -0.00822492 |
| NID2 | nidogen 2 (osteonidogen) | -0.00820202 |
| CDA | cytidine deaminase | -0.0081817 |
| KLHL41 | kelch-like family member 41 | -0.00816338 |
| TMEM255A | transmembrane protein 255A | -0.00804149 |
| CPE | carboxypeptidase E | -0.00789103 |
| VWF | von Willebrand factor | -0.00787393 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.00780023 |
| ACTA1 | actin, alpha 1, skeletal muscle | -0.00774899 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | -0.00774285 |
| PPL | periplakin | -0.00772708 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | -0.0076955 |
| SPRR1B | small proline-rich protein 1B | -0.00765843 |
| ACTB | actin, beta | -0.00751457 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.00742614 |
| ADM | adrenomedullin | -0.00739506 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | -0.00735942 |
| KLK13 | kallikrein-related peptidase 13 | -0.00734197 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.00729634 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.00714434 |
| RHCG | Rh family, C glycoprotein | -0.00703596 |
| EMP1 | epithelial membrane protein 1 | -0.00702291 |
| COL4A2 | collagen, type IV, alpha 2 | -0.00698414 |
| CRCT1 | cysteine-rich C-terminal 1 | -0.00698174 |
| DUOX2 | dual oxidase 2 | -0.00698033 |
| ANGPT2 | angiopoietin 2 | -0.00697769 |
| F12 | coagulation factor XII (Hageman factor) | -0.00696371 |
| TUBB2B | tubulin, beta 2B class IIb | -0.00692465 |
| CKM | creatine kinase, muscle | -0.0069124 |
| MYOT | myotilin | -0.00686492 |
| HOXB6 | homeobox B6 | -0.00681053 |
| GPC3 | glypican 3 | -0.00680793 |
| TXNIP | thioredoxin interacting protein | -0.00679691 |
| NEFM | neurofilament, medium polypeptide | -0.00676443 |
| VCL | vinculin | -0.00675774 |
| SMCO4 | single-pass membrane protein with coiled-coil domains 4 | -0.00672929 |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 | -0.00668743 |
| UPP1 | uridine phosphorylase 1 | -0.00665148 |
| VNN1 | vanin 1 | -0.00663819 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | -0.00660966 |
| TUBB2A | tubulin, beta 2A class IIa | -0.00658516 |
| SGCE | sarcoglycan, epsilon | -0.0065825 |
| NPTX2 | neuronal pentraxin II | -0.00654884 |
| KLK12 | kallikrein-related peptidase 12 | -0.0065158 |
| SPRR3 | small proline-rich protein 3 | -0.00648284 |
| TTN | titin | -0.00647185 |
| PLK1 | polo-like kinase 1 | -0.00647009 |
| ZNF185 | zinc finger protein 185 (LIM domain) | -0.00646211 |
| ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) | -0.00644351 |
| ECM1 | extracellular matrix protein 1 | -0.00639907 |
| CLTB | clathrin, light chain B | -0.00638337 |
| BSG | basigin (Ok blood group) | -0.00635532 |
| IL1RN | interleukin 1 receptor antagonist | -0.00631692 |
| PRPH | peripherin | -0.00626673 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.00625726 |
| PLS3 | plastin 3 | -0.00623934 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.00614233 |
| GIMAP4 | GTPase, IMAP family member 4 | -0.00614152 |
| SNX10 | sorting nexin 10 | -0.00612551 |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 | -0.00611417 |
| COL6A2 | collagen, type VI, alpha 2 | -0.00611355 |
| TNFRSF1A | tumor necrosis factor receptor superfamily, member 1A | -0.00606903 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.00605309 |
| MIA | melanoma inhibitory activity | -0.00601892 |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase | -0.00601331 |
| TNNI1 | troponin I type 1 (skeletal, slow) | -0.00600134 |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | -0.00599533 |
| INHBB | inhibin, beta B | -0.00595052 |
| LPIN1 | lipin 1 | -0.00593068 |
| COL15A1 | collagen, type XV, alpha 1 | -0.00592321 |
| TNNC2 | troponin C type 2 (fast) | -0.00590593 |
| PXDN | peroxidasin | -0.00590456 |
| KLF4 | Kruppel-like factor 4 (gut) | -0.00589686 |
| RTN4 | reticulon 4 | -0.00589015 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | -0.00588164 |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 | -0.00588118 |
| SPRR1A | small proline-rich protein 1A | -0.00587151 |
| MYLPF | myosin light chain, phosphorylatable, fast skeletal muscle | -0.005869 |
| ATP6V1A | ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A | -0.00585535 |
| YBX3 | Y box binding protein 3 | -0.00583025 |
| FCGBP | Fc fragment of IgG binding protein | -0.00582258 |
| PLVAP | plasmalemma vesicle associated protein | -0.00581479 |
| MGLL | monoglyceride lipase | -0.00580558 |
| PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | -0.00580445 |
| IL18 | interleukin 18 | -0.00579421 |
| GRB14 | growth factor receptor-bound protein 14 | -0.00578075 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0057754 |
| EMP2 | epithelial membrane protein 2 | -0.005767 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -0.0057338 |
| CARD10 | caspase recruitment domain family, member 10 | -0.00572271 |
| MYBPC1 | myosin binding protein C, slow type | -0.00570351 |
| USP13 | ubiquitin specific peptidase 13 (isopeptidase T-3) | -0.00568641 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.00568488 |
| FLT1 | fms-related tyrosine kinase 1 | -0.00567756 |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast | -0.0056536 |
| DAPK1 | death-associated protein kinase 1 | -0.00560256 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.00558615 |
| TMPRSS11E | transmembrane protease, serine 11E | -0.00557151 |
| BCL3 | B-cell CLL/lymphoma 3 | -0.00557033 |
| GCG | glucagon | -0.00555202 |
| TNNC1 | troponin C type 1 (slow) | -0.00552681 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | -0.00551776 |
| RBM47 | RNA binding motif protein 47 | -0.00550208 |
| TGM1 | transglutaminase 1 | -0.0054875 |
| TMEM38B | transmembrane protein 38B | -0.00548248 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.00548165 |
| ANGPTL2 | angiopoietin-like 2 | -0.0054722 |
| CRNN | cornulin | -0.0054666 |
| SDC1 | syndecan 1 | -0.00546016 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.0054409 |
| GPX3 | glutathione peroxidase 3 | -0.00543511 |
| SPATA20 | spermatogenesis associated 20 | -0.00541888 |
| MPZ | myelin protein zero | -0.00539509 |
| CD14 | CD14 molecule | -0.00538958 |
| TNNI2 | troponin I type 2 (skeletal, fast) | -0.00536677 |
| APOB | apolipoprotein B | -0.00535016 |
| GOLM1 | golgi membrane protein 1 | -0.005348 |
| ADGRE1 | adhesion G protein-coupled receptor E1 | -0.00534151 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.00533639 |
| LAMA4 | laminin, alpha 4 | -0.0053174 |
| PCMTD2 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 | -0.00531112 |
| ITPKB | inositol-trisphosphate 3-kinase B | -0.00527523 |
| SNRK | SNF related kinase | -0.0052563 |
| CMAS | cytidine monophosphate N-acetylneuraminic acid synthetase | -0.00524944 |
| IVL | involucrin | -0.00524086 |
| LITAF | lipopolysaccharide-induced TNF factor | -0.00523149 |
| MALL | mal, T-cell differentiation protein-like | -0.00522811 |
| SELL | selectin L | -0.00522513 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | -0.00521257 |
| CCNB1 | cyclin B1 | -0.00520094 |
| MYL2 | myosin, light chain 2, regulatory, cardiac, slow | -0.00519281 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | -0.00519165 |
| PRSS3 | protease, serine, 3 | -0.00518311 |
| FOXN3 | forkhead box N3 | -0.00515917 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | -0.00515436 |
| PGGHG | protein-glucosylgalactosylhydroxylysine glucosidase | -0.00514964 |
| KRT1 | keratin 1, type II | -0.00514856 |
| MZB1 | marginal zone B and B1 cell-specific protein | -0.00514401 |
| APOBEC3A | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A | -0.00513994 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.00511869 |
| JAG2 | jagged 2 | -0.00510192 |
| UBE2G1 | ubiquitin-conjugating enzyme E2G 1 | -0.00509616 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.00509559 |
| AKAP8L | A kinase (PRKA) anchor protein 8-like | -0.00505618 |
| HOXB2 | homeobox B2 | -0.00505205 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | -0.00505161 |
| SLC6A15 | solute carrier family 6 (neutral amino acid transporter), member 15 | -0.005034 |
| TSPAN7 | tetraspanin 7 | -0.00503032 |
| SPRR2B | small proline-rich protein 2B | -0.00502598 |
| FKBP5 | FK506 binding protein 5 | -0.00501741 |
| DSG3 | desmoglein 3 | -0.0050162 |
| ENO3 | enolase 3 (beta, muscle) | -0.00501123 |
| TADA2A | transcriptional adaptor 2A | -0.004998 |
| REG3A | regenerating islet-derived 3 alpha | -0.00497904 |
| ADIPOR2 | adiponectin receptor 2 | -0.0049782 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | -0.00497728 |
| CLMN | calmin (calponin-like, transmembrane) | -0.00496742 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.00495797 |
| SST | somatostatin | -0.00495229 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | -0.00494995 |
| CS | citrate synthase | -0.00493288 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.00493126 |
| TIE1 | tyrosine kinase with immunoglobulin-like and EGF-like domains 1 | -0.00492638 |
| KRT6A | keratin 6A, type II | -0.0049261 |
| TGFB1 | transforming growth factor, beta 1 | -0.00492131 |
| STMN2 | stathmin 2 | -0.00492129 |
| CALCA | calcitonin-related polypeptide alpha | -0.00492045 |
| PRR5 | proline rich 5 (renal) | -0.00491809 |
| CLCA4 | chloride channel accessory 4 | -0.00491396 |
| KRT17 | keratin 17, type I | -0.00489464 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.00488705 |
| KLF10 | Kruppel-like factor 10 | -0.00488036 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.00487819 |
| KRT13 | keratin 13, type I | -0.00487334 |
| TGM3 | transglutaminase 3 | -0.00486107 |
| BCKDK | branched chain ketoacid dehydrogenase kinase | -0.00484991 |
| INSR | insulin receptor | -0.00484526 |
| ABCA6 | ATP-binding cassette, sub-family A (ABC1), member 6 | -0.00484503 |
| GAS1 | growth arrest-specific 1 | -0.00482569 |
| MEF2C | myocyte enhancer factor 2C | -0.0048192 |
| TAOK3 | TAO kinase 3 | -0.00481867 |
| POLR3G | polymerase (RNA) III (DNA directed) polypeptide G (32kD) | -0.00481553 |
| PLXNB2 | plexin B2 | -0.00480213 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.00479788 |
| SRSF5 | serine/arginine-rich splicing factor 5 | -0.00479683 |
| EMC2 | ER membrane protein complex subunit 2 | -0.00479047 |
| HDGFL3 | HDGF like 3 | -0.00478768 |
| OAZ2 | ornithine decarboxylase antizyme 2 | -0.00477233 |
| KYNU | kynureninase | -0.00475957 |
| ACTN4 | actinin, alpha 4 | -0.00475068 |
| TYMP | thymidine phosphorylase | -0.00475018 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.00473889 |
| PTK2 | protein tyrosine kinase 2 | -0.00473528 |
| MSX1 | msh homeobox 1 | -0.0047273 |
| UBE2S | ubiquitin-conjugating enzyme E2S | -0.00472341 |
| PRPF31 | pre-mRNA processing factor 31 | -0.00472006 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.00471977 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0047167 |
| S100A2 | S100 calcium binding protein A2 | -0.00469574 |
| P2RY14 | purinergic receptor P2Y, G-protein coupled, 14 | -0.00469557 |
| SUN1 | Sad1 and UNC84 domain containing 1 | -0.00469027 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.00468911 |
| DCHS1 | dachsous cadherin-related 1 | -0.00468855 |
| PLXDC1 | plexin domain containing 1 | -0.00468763 |
| WASL | Wiskott-Aldrich syndrome-like | -0.00468487 |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like | -0.00468309 |
| APOA2 | apolipoprotein A-II | -0.00466731 |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 | -0.00466221 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.00465831 |
| PALMD | palmdelphin | -0.0046571 |
| EHBP1 | EH domain binding protein 1 | -0.0046457 |
| DSC2 | desmocollin 2 | -0.00464491 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | -0.00464282 |
