| Dataset | Pathway Commons Protein-Protein Interactions |
| Category | physical interactions |
| Type | interacting protein |
| Description | methylenetetrahydrofolate reductase (NAD(P)H)|The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.[provided by RefSeq, Oct 2009] (NCBI Entrez Gene Database, 4524) |
| External Link | http://www.ncbi.nlm.nih.gov/gene/4524 |
| Similar Terms | |
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2 interacting proteins for MTHFR from the Pathway Commons Protein-Protein Interactions dataset.