MTHFS Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)|The protein encoded by this gene is an enzyme that catalyzes the conversion of 5-formyltetrahydrofolate to 5,10-methenyltetrahydrofolate, a precursor of reduced folates involved in 1-carbon metabolism. An increased activity of the encoded protein can result in an increased folate turnover rate and folate depletion. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2011] (NCBI Entrez Gene Database, 10588)
External Link http://www.ncbi.nlm.nih.gov/gene/10588
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Genes

4 interacting proteins for MTHFS from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
HNF4A hepatocyte nuclear factor 4, alpha
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TSC22D4 TSC22 domain family, member 4
UBC ubiquitin C