| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | melatonin receptor 1A|This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 4543) |
| External Link | https://ncbi.nlm.nih.gov/gene/4543 |
| Similar Terms | |
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499 genes differentially expressed following the MTNR1A gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IFITM1 | interferon induced transmembrane protein 1 | 0.0128227 |
| FASN | fatty acid synthase | 0.0108168 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0101592 |
| CCP110 | centriolar coiled coil protein 110kDa | 0.00997398 |
| EVI2A | ecotropic viral integration site 2A | 0.00993707 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 0.00986408 |
| STK10 | serine/threonine kinase 10 | 0.00972048 |
| EPCAM | epithelial cell adhesion molecule | 0.00970614 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.00911467 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | 0.00886744 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.0087083 |
| RB1 | retinoblastoma 1 | 0.00866675 |
| EFHD1 | EF-hand domain family, member D1 | 0.00859696 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 0.00836447 |
| CLDN3 | claudin 3 | 0.00836326 |
| IFITM2 | interferon induced transmembrane protein 2 | 0.00834215 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.00826978 |
| SYT1 | synaptotagmin I | 0.00814688 |
| MECOM | MDS1 and EVI1 complex locus | 0.00785306 |
| FCGR3B | Fc fragment of IgG, low affinity IIIb, receptor (CD16b) | 0.00774447 |
| FCGR2B | Fc fragment of IgG, low affinity IIb, receptor (CD32) | 0.00772752 |
| MAGEA3 | melanoma antigen family A3 | 0.00770329 |
| BGN | biglycan | 0.0076679 |
| SH3BP4 | SH3-domain binding protein 4 | 0.0076579 |
| CNPY3 | canopy FGF signaling regulator 3 | 0.00765085 |
| CCNF | cyclin F | 0.00761623 |
| C3ORF14 | chromosome 3 open reading frame 14 | 0.0075518 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.00754438 |
| CD300A | CD300a molecule | 0.00752686 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | 0.00749413 |
| CCNA2 | cyclin A2 | 0.0074644 |
| GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) | 0.00745533 |
| SLC2A4RG | SLC2A4 regulator | 0.00742133 |
| HMGN5 | high mobility group nucleosome binding domain 5 | 0.007355 |
| GLO1 | glyoxalase I | 0.00733927 |
| CD48 | CD48 molecule | 0.00721255 |
| KIAA0100 | KIAA0100 | 0.00719161 |
| DAPK1 | death-associated protein kinase 1 | 0.00702987 |
| OIP5 | Opa interacting protein 5 | 0.00700572 |
| TMSB15A | thymosin beta 15a | 0.00699023 |
| CBX3 | chromobox homolog 3 | 0.00697773 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | 0.00696786 |
| DACH1 | dachshund family transcription factor 1 | 0.0069673 |
| DCXR | dicarbonyl/L-xylulose reductase | 0.00695879 |
| BIRC5 | baculoviral IAP repeat containing 5 | 0.00680341 |
| ABHD4 | abhydrolase domain containing 4 | 0.00679641 |
| ITGA4 | integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) | 0.00679513 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 | 0.00671551 |
| APIP | APAF1 interacting protein | 0.00666835 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.00663751 |
| THAP12 | THAP domain containing 12 | 0.006626 |
| PRRC2A | proline-rich coiled-coil 2A | 0.00656312 |
| CLGN | calmegin | 0.0065171 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.00648821 |
| RXRA | retinoid X receptor, alpha | 0.00647278 |
| PODXL | podocalyxin-like | 0.00644483 |
| TCF12 | transcription factor 12 | 0.00636952 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 0.00635572 |
| GRP | gastrin-releasing peptide | 0.00634308 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.00630235 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.00628442 |
| STK3 | serine/threonine kinase 3 | 0.00627431 |
| ALG8 | ALG8, alpha-1,3-glucosyltransferase | 0.00625033 |
| TXNDC9 | thioredoxin domain containing 9 | 0.00623873 |
| PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H | 0.00622765 |
| FGFR3 | fibroblast growth factor receptor 3 | 0.00619336 |
| WASHC4 | WASH complex subunit 4 | 0.0061694 |
| DSCC1 | DNA replication and sister chromatid cohesion 1 | 0.00615912 |
| SAC3D1 | SAC3 domain containing 1 | 0.00614678 |
| JCHAIN | joining chain of multimeric IgA and IgM | 0.00614555 |
| CIT | citron rho-interacting serine/threonine kinase | 0.00613973 |
| PKP4 | plakophilin 4 | 0.00611748 |
| KIF20A | kinesin family member 20A | 0.0061021 |
| MYCL | v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog | 0.0060945 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | 0.00608611 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | 0.00608122 |
| NNMT | nicotinamide N-methyltransferase | 0.00604529 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | 0.00603375 |
| SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 | 0.00601593 |
| LCP2 | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) | 0.00601485 |
| GAMT | guanidinoacetate N-methyltransferase | 0.00600536 |
| SIGIRR | single immunoglobulin and toll-interleukin 1 receptor (TIR) domain | 0.00599046 |
| HMGB3 | high mobility group box 3 | 0.00597742 |
| LEPR | leptin receptor | 0.00595712 |
| ZNF652 | zinc finger protein 652 | 0.00594539 |
| THY1 | Thy-1 cell surface antigen | 0.00592304 |
| LSM2 | LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00590867 |
| INSIG1 | insulin induced gene 1 | 0.0058921 |
| KLHDC3 | kelch domain containing 3 | 0.00587777 |
| SIX1 | SIX homeobox 1 | 0.00586777 |
| GCA | grancalcin, EF-hand calcium binding protein | 0.00586545 |
| BIN2 | bridging integrator 2 | 0.00586221 |
| XAF1 | XIAP associated factor 1 | 0.00584846 |
| RMI1 | RecQ mediated genome instability 1 | 0.0058418 |
| EEF1E1 | eukaryotic translation elongation factor 1 epsilon 1 | 0.00582423 |
| MAP2K6 | mitogen-activated protein kinase kinase 6 | 0.00580516 |
| PLXNC1 | plexin C1 | 0.00579334 |
| SLC27A5 | solute carrier family 27 (fatty acid transporter), member 5 | 0.00574017 |
| RHOB | ras homolog family member B | 0.00569662 |
| YEATS4 | YEATS domain containing 4 | 0.00568617 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.00568423 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0056792 |
| ASF1A | anti-silencing function 1A histone chaperone | 0.00565064 |
| TPGS2 | tubulin polyglutamylase complex subunit 2 | 0.00561413 |
| MFAP2 | microfibrillar-associated protein 2 | 0.00561307 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | 0.00559242 |
| C12ORF29 | chromosome 12 open reading frame 29 | 0.00557621 |
| PSIP1 | PC4 and SFRS1 interacting protein 1 | 0.00556646 |
| GATA2 | GATA binding protein 2 | 0.00556223 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | 0.00554664 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | 0.00554431 |
| CLNS1A | chloride channel, nucleotide-sensitive, 1A | 0.00552894 |
| TWIST1 | twist family bHLH transcription factor 1 | 0.00551337 |
| MMP11 | matrix metallopeptidase 11 | 0.00550843 |
| TDO2 | tryptophan 2,3-dioxygenase | 0.00550293 |
| NFE2 | nuclear factor, erythroid 2 | 0.00550045 |
| MZB1 | marginal zone B and B1 cell-specific protein | 0.00549385 |
| RBBP8 | retinoblastoma binding protein 8 | 0.00542273 |
| ELN | elastin | 0.00539198 |
| KRT7 | keratin 7, type II | 0.00539189 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | 0.00538323 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.00538186 |
| ARL3 | ADP-ribosylation factor-like 3 | 0.00537899 |
| TMEM176A | transmembrane protein 176A | 0.00536748 |
| LACTB2 | lactamase, beta 2 | 0.00535116 |
| TMEM106C | transmembrane protein 106C | 0.00534948 |
| TAGLN | transgelin | 0.00533786 |
| SUB1 | SUB1 homolog (S. cerevisiae) | 0.00533158 |
| FRAT2 | frequently rearranged in advanced T-cell lymphomas 2 | 0.0053104 |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) | 0.0053084 |
| NRGN | neurogranin (protein kinase C substrate, RC3) | 0.00530508 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | 0.0052865 |
| SREBF1 | sterol regulatory element binding transcription factor 1 | 0.00527128 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) | 0.0052657 |
| ZCCHC10 | zinc finger, CCHC domain containing 10 | 0.00523993 |
| CKAP2 | cytoskeleton associated protein 2 | 0.00523814 |
| HMGB1 | high mobility group box 1 | 0.00523558 |
| CCR1 | chemokine (C-C motif) receptor 1 | 0.00522842 |
| AEBP1 | AE binding protein 1 | 0.0052142 |
| TBCD | tubulin folding cofactor D | 0.00520119 |
| PRDX2 | peroxiredoxin 2 | 0.00519764 |
| TSPAN13 | tetraspanin 13 | 0.00519476 |
| RCN2 | reticulocalbin 2, EF-hand calcium binding domain | 0.00519237 |
| GGCT | gamma-glutamylcyclotransferase | 0.00518443 |
| WFDC2 | WAP four-disulfide core domain 2 | 0.00518039 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | 0.00514907 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.00514672 |
| TMEM14A | transmembrane protein 14A | 0.00514501 |
| MICU2 | mitochondrial calcium uptake 2 | 0.00514331 |
| CPB1 | carboxypeptidase B1 (tissue) | 0.00513024 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | 0.00512242 |
| ENPP4 | ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) | 0.00511402 |
| ASNSD1 | asparagine synthetase domain containing 1 | 0.00511354 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.00510962 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.0050963 |
| RPA3 | replication protein A3, 14kDa | 0.00506906 |
| ITM2C | integral membrane protein 2C | 0.0050661 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D | 0.00506205 |
| CRY1 | cryptochrome circadian clock 1 | 0.00505454 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 | 0.0050355 |
| PAK1IP1 | PAK1 interacting protein 1 | 0.00503357 |
| ANKRD46 | ankyrin repeat domain 46 | 0.00500533 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | 0.00500407 |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit | 0.00500246 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | 0.00500198 |
| IL2RB | interleukin 2 receptor, beta | 0.00499343 |
| F2R | coagulation factor II (thrombin) receptor | 0.00498159 |
| SHTN1 | shootin 1 | 0.00497308 |
| MED13L | mediator complex subunit 13-like | 0.00496215 |
| SNX10 | sorting nexin 10 | 0.00495721 |
| NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor | 0.00493407 |
| PRKCB | protein kinase C, beta | 0.00493308 |
| KAZN | kazrin, periplakin interacting protein | 0.00492689 |
| STAU2 | staufen double-stranded RNA binding protein 2 | 0.00492645 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A | 0.00491887 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.00491785 |
| SMYD2 | SET and MYND domain containing 2 | 0.00491704 |
| CREB1 | cAMP responsive element binding protein 1 | 0.00491541 |
| HIST3H2A | histone cluster 3, H2a | 0.00490738 |
| PBK | PDZ binding kinase | 0.00489698 |
| CRADD | CASP2 and RIPK1 domain containing adaptor with death domain | 0.00489342 |
| TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 | 0.00488897 |
| CEL | carboxyl ester lipase | 0.00488448 |
| CHST12 | carbohydrate (chondroitin 4) sulfotransferase 12 | 0.00487706 |
| DEK | DEK proto-oncogene | 0.0048742 |
| SGMS1 | sphingomyelin synthase 1 | 0.00486135 |
| KLHL23 | kelch-like family member 23 | 0.00485637 |
| EHMT2 | euchromatic histone-lysine N-methyltransferase 2 | 0.00484175 |
| FRZB | frizzled-related protein | 0.00483584 |
| AASDHPPT | aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase | 0.00482558 |
| RFK | riboflavin kinase | 0.00482058 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 | 0.00480731 |
| H2AFV | H2A histone family, member V | 0.00480387 |
| USP18 | ubiquitin specific peptidase 18 | 0.00476685 |
| MAGEA12 | melanoma antigen family A12 | 0.00476506 |
| GNG10 | guanine nucleotide binding protein (G protein), gamma 10 | 0.00475646 |
| HSD17B8 | hydroxysteroid (17-beta) dehydrogenase 8 | 0.00475621 |
| WBP5 | WW domain binding protein 5 | 0.00475073 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | 0.00474738 |
| DCK | deoxycytidine kinase | 0.0047473 |
| PPP1R14B | protein phosphatase 1, regulatory (inhibitor) subunit 14B | 0.00474548 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.00473687 |
| ERG | v-ets avian erythroblastosis virus E26 oncogene homolog | 0.00473566 |
| CRLF3 | cytokine receptor-like factor 3 | 0.00473176 |
| SPAG5 | sperm associated antigen 5 | 0.00472991 |
| SRP9 | signal recognition particle 9kDa | 0.00472105 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.00471622 |
| NDUFB6 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa | 0.00470751 |
| CSTF2T | cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant | 0.00470242 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | 0.00470188 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | 0.00470162 |
| TMEM176B | transmembrane protein 176B | 0.00470125 |
| SNRPG | small nuclear ribonucleoprotein polypeptide G | 0.00469371 |
| CXADR | coxsackie virus and adenovirus receptor | 0.00469212 |
| CD320 | CD320 molecule | 0.00469191 |
| CRYM | crystallin, mu | 0.00469114 |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) | 0.00468925 |
| JADE2 | jade family PHD finger 2 | 0.00468791 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0046844 |
| RAD21 | RAD21 homolog (S. pombe) | 0.00468089 |
| THBS1 | thrombospondin 1 | 0.00467896 |
| MTARC1 | mitochondrial amidoxime reducing component 1 | 0.00467439 |
| CEP70 | centrosomal protein 70kDa | 0.00466592 |
| COL18A1 | collagen, type XVIII, alpha 1 | 0.00463532 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.00461601 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.00461391 |
| FBN1 | fibrillin 1 | 0.00461237 |
| PIGC | phosphatidylinositol glycan anchor biosynthesis, class C | 0.00461079 |
| SLC25A15 | solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 | 0.00460983 |
| MTERF3 | mitochondrial transcription termination factor 3 | 0.00459867 |
| CDK1 | cyclin-dependent kinase 1 | 0.00459456 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | 0.00459353 |
| CLEC11A | C-type lectin domain family 11, member A | 0.00458849 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.00458575 |
| ACTR6 | ARP6 actin-related protein 6 homolog (yeast) | 0.00458184 |
| S1PR4 | sphingosine-1-phosphate receptor 4 | 0.00458118 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.00458074 |
| MRPL48 | mitochondrial ribosomal protein L48 | 0.00457393 |
| FAM216A | family with sequence similarity 216, member A | 0.00456906 |
| CENPX | centromere protein X | 0.00456683 |
| NELL2 | NEL-like 2 (chicken) | 0.00456287 |
| KIF18B | kinesin family member 18B | 0.00456022 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.00454745 |
| IFI44L | interferon-induced protein 44-like | 0.0045456 |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 | 0.00454195 |
| FOLR1 | folate receptor 1 (adult) | 0.00452525 |
| CHN2 | chimerin 2 | 0.00452478 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | 0.00451021 |
| NPM3 | nucleophosmin/nucleoplasmin 3 | 0.00450985 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TM4SF1 | transmembrane 4 L six family member 1 | -0.014754 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0141426 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | -0.013253 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0118855 |
| SRPX | sushi-repeat containing protein, X-linked | -0.0116916 |
| HSPA1A | heat shock 70kDa protein 1A | -0.0112717 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.0108175 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | -0.0107213 |
| KYNU | kynureninase | -0.0103635 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0102785 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | -0.0102657 |
| FHL1 | four and a half LIM domains 1 | -0.00984535 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 | -0.00966141 |
| CRYAB | crystallin, alpha B | -0.0096309 |
| PDE8B | phosphodiesterase 8B | -0.0094318 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.00941872 |
| AREG | amphiregulin | -0.00940054 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.0089479 |
| C3 | complement component 3 | -0.00892293 |
| PEG3 | paternally expressed 3 | -0.00860341 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.00855736 |
| ATF3 | activating transcription factor 3 | -0.00855647 |
| HMOX1 | heme oxygenase 1 | -0.00853862 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.00838364 |
| DES | desmin | -0.00831453 |
| DUSP5 | dual specificity phosphatase 5 | -0.00828142 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | -0.00826951 |
| SSPN | sarcospan | -0.00826367 |
| S100A10 | S100 calcium binding protein A10 | -0.00817744 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | -0.00813996 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | -0.00803922 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.00789286 |
| COL6A3 | collagen, type VI, alpha 3 | -0.00789281 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.00787425 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | -0.00784434 |
| SMAD3 | SMAD family member 3 | -0.00775531 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | -0.00747812 |
| MET | MET proto-oncogene, receptor tyrosine kinase | -0.00746818 |
| MCL1 | myeloid cell leukemia 1 | -0.00744351 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -0.00743409 |
| PDZK1IP1 | PDZK1 interacting protein 1 | -0.00742441 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.00736805 |
| KRT15 | keratin 15, type I | -0.00731541 |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 | -0.0073149 |
| MVP | major vault protein | -0.0072277 |
| FN1 | fibronectin 1 | -0.00721782 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.00721142 |
| S100P | S100 calcium binding protein P | -0.0072088 |
| ALB | albumin | -0.0071451 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.00714298 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | -0.0071188 |
| CTSE | cathepsin E | -0.00711166 |
| PRNP | prion protein | -0.00707924 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | -0.00707652 |
| RGS13 | regulator of G-protein signaling 13 | -0.00706331 |
| GLA | galactosidase, alpha | -0.00705622 |
| EIF5 | eukaryotic translation initiation factor 5 | -0.00704809 |
| PYGB | phosphorylase, glycogen; brain | -0.00703123 |
| CCNB1 | cyclin B1 | -0.00698382 |
| SYNM | synemin, intermediate filament protein | -0.00697816 |
| GM2A | GM2 ganglioside activator | -0.0069429 |
| ASPH | aspartate beta-hydroxylase | -0.00694017 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.0069255 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | -0.00692251 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.00689796 |
| FABP7 | fatty acid binding protein 7, brain | -0.00688462 |
| C7 | complement component 7 | -0.0068762 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | -0.0068619 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.00685955 |
| ACKR1 | atypical chemokine receptor 1 (Duffy blood group) | -0.0068582 |
| CTSA | cathepsin A | -0.00678772 |
| APOB | apolipoprotein B | -0.00678288 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.00677611 |
| MCAM | melanoma cell adhesion molecule | -0.00676898 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.00674861 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | -0.00673243 |
| MT1X | metallothionein 1X | -0.00669708 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.00665435 |
| LY75 | lymphocyte antigen 75 | -0.00660071 |
| C1S | complement component 1, s subcomponent | -0.00659385 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.00657239 |
| KANK1 | KN motif and ankyrin repeat domains 1 | -0.00655437 |
| GLRX | glutaredoxin (thioltransferase) | -0.0065542 |
| EIF5A | eukaryotic translation initiation factor 5A | -0.00653304 |
| ATP10B | ATPase, class V, type 10B | -0.00652905 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 | -0.00651242 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.006512 |
| HAND2-AS1 | HAND2 antisense RNA 1 (head to head) | -0.0064913 |
| PKP1 | plakophilin 1 | -0.00648691 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.00648127 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.00643855 |
| LY6D | lymphocyte antigen 6 complex, locus D | -0.00642599 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0064099 |
| MAOB | monoamine oxidase B | -0.00640875 |
| BHLHE41 | basic helix-loop-helix family, member e41 | -0.00639625 |
| CTSB | cathepsin B | -0.00639351 |
| EGR3 | early growth response 3 | -0.00638678 |
| ZNF185 | zinc finger protein 185 (LIM domain) | -0.00638335 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.00637901 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0063777 |
| KLF4 | Kruppel-like factor 4 (gut) | -0.00637397 |
| DHDDS | dehydrodolichyl diphosphate synthase | -0.00637218 |
| MITF | microphthalmia-associated transcription factor | -0.00634683 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | -0.00630408 |
| GSPT2 | G1 to S phase transition 2 | -0.00629788 |
| JAG1 | jagged 1 | -0.00627595 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | -0.00627487 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.00627399 |
| FGG | fibrinogen gamma chain | -0.0062739 |
| TFF2 | trefoil factor 2 | -0.00625276 |
| G0S2 | G0/G1 switch 2 | -0.00623038 |
| ITIH5 | inter-alpha-trypsin inhibitor heavy chain family, member 5 | -0.00622827 |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide | -0.00620965 |
| FILIP1L | filamin A interacting protein 1-like | -0.00620783 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | -0.00619475 |
| IL17RB | interleukin 17 receptor B | -0.00616391 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.00616067 |
| LAMB1 | laminin, beta 1 | -0.00615794 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.00614802 |
| STC2 | stanniocalcin 2 | -0.00613261 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | -0.00609356 |
| IER5 | immediate early response 5 | -0.00608619 |
| FOXO1 | forkhead box O1 | -0.00607491 |
| SLC38A1 | solute carrier family 38, member 1 | -0.00607293 |
| SPRR3 | small proline-rich protein 3 | -0.00603403 |
| ECM1 | extracellular matrix protein 1 | -0.00603043 |
| OAT | ornithine aminotransferase | -0.00602985 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.00602059 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | -0.00601637 |
| VEGFC | vascular endothelial growth factor C | -0.00601548 |
| TLCD3A | TLC domain containing 3A | -0.00600472 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | -0.00599609 |
| GOLGB1 | golgin B1 | -0.00599123 |
| SERPINB8 | serpin peptidase inhibitor, clade B (ovalbumin), member 8 | -0.0059651 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.00595924 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.0059558 |
| CYB5R2 | cytochrome b5 reductase 2 | -0.00595422 |
| DUOX2 | dual oxidase 2 | -0.00592224 |
| LDB3 | LIM domain binding 3 | -0.00590087 |
| DSC2 | desmocollin 2 | -0.00588162 |
| SOBP | sine oculis binding protein homolog (Drosophila) | -0.00587641 |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) | -0.00587312 |
| IL6R | interleukin 6 receptor | -0.00584353 |
| ABCB1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 | -0.00584092 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.00583407 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.00582265 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | -0.00582013 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.00581899 |
| COL6A1 | collagen, type VI, alpha 1 | -0.00581432 |
| PSCA | prostate stem cell antigen | -0.00580056 |
| HLA-B | major histocompatibility complex, class I, B | -0.00578975 |
| TMPRSS11E | transmembrane protease, serine 11E | -0.00578663 |
| EGR1 | early growth response 1 | -0.00578374 |
| DNAJC2 | DnaJ (Hsp40) homolog, subfamily C, member 2 | -0.00578076 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 | -0.00575563 |
| CAST | calpastatin | -0.00574844 |
| PRKCA | protein kinase C, alpha | -0.0057479 |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit | -0.00572743 |
| LMOD1 | leiomodin 1 (smooth muscle) | -0.00572442 |
| ABLIM1 | actin binding LIM protein 1 | -0.00571012 |
| SFRP1 | secreted frizzled-related protein 1 | -0.00571002 |
| SORBS1 | sorbin and SH3 domain containing 1 | -0.00571001 |
| PSAP | prosaposin | -0.00569023 |
| CLCA4 | chloride channel accessory 4 | -0.00568656 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.00568454 |
| DCHS1 | dachsous cadherin-related 1 | -0.00567747 |
| CFD | complement factor D (adipsin) | -0.00565859 |
| AGR2 | anterior gradient 2 | -0.00565126 |
| TMEM255A | transmembrane protein 255A | -0.00564978 |
| MGLL | monoglyceride lipase | -0.00561791 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.00561576 |
| SMTN | smoothelin | -0.00561547 |
| NRCAM | neuronal cell adhesion molecule | -0.00561507 |
| FGB | fibrinogen beta chain | -0.00561112 |
| CRCT1 | cysteine-rich C-terminal 1 | -0.00560414 |
| ADGRG2 | adhesion G protein-coupled receptor G2 | -0.00557232 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.00556456 |
| BMP2 | bone morphogenetic protein 2 | -0.00555873 |
| FOXF1 | forkhead box F1 | -0.0055584 |
| MAOA | monoamine oxidase A | -0.00555666 |
| FOSL2 | FOS-like antigen 2 | -0.00554625 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit | -0.00554449 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | -0.0055333 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | -0.00552451 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | -0.00551276 |
| TLE4 | transducin-like enhancer of split 4 | -0.00550124 |
| KRT6A | keratin 6A, type II | -0.00550066 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.00546527 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | -0.0054571 |
| SPRR2B | small proline-rich protein 2B | -0.00542594 |
| STOM | stomatin | -0.00542268 |
| BAG3 | BCL2-associated athanogene 3 | -0.00538653 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.00538622 |
| ZBTB35 | zinc finger and BTB domain containing 35 | -0.00538283 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | -0.00537859 |
| IFNGR1 | interferon gamma receptor 1 | -0.00537725 |
| TMEM43 | transmembrane protein 43 | -0.00536725 |
| RHCG | Rh family, C glycoprotein | -0.00536594 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.00536304 |
| FEM1C | fem-1 homolog c (C. elegans) | -0.0053565 |
| DLD | dihydrolipoamide dehydrogenase | -0.0053479 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.00534279 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.00533775 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 | -0.0053368 |
| ITGA6 | integrin, alpha 6 | -0.00533619 |
| ERP44 | endoplasmic reticulum protein 44 | -0.00533319 |
| RBPMS | RNA binding protein with multiple splicing | -0.00533256 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | -0.00532742 |
| MIR22HG | MIR22 host gene | -0.00531299 |
| ITGA7 | integrin, alpha 7 | -0.00531105 |
| MXI1 | MAX interactor 1, dimerization protein | -0.00530254 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.00530187 |
| KCTD12 | potassium channel tetramerization domain containing 12 | -0.00529041 |
| BEX1 | brain expressed, X-linked 1 | -0.00528579 |
| REG1A | regenerating islet-derived 1 alpha | -0.00527673 |
| SETBP1 | SET binding protein 1 | -0.00527327 |
| EPHA2 | EPH receptor A2 | -0.00526508 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | -0.00526389 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.00526271 |
| PITX1 | paired-like homeodomain 1 | -0.00526147 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.00525471 |
| SERPINB7 | serpin peptidase inhibitor, clade B (ovalbumin), member 7 | -0.0052518 |
| STC1 | stanniocalcin 1 | -0.00524984 |
| HOPX | HOP homeobox | -0.00524298 |
| VNN1 | vanin 1 | -0.0052348 |
| BCL2A1 | BCL2-related protein A1 | -0.00522855 |
| KRT81 | keratin 81, type II | -0.00522645 |
| DMTF1 | cyclin D binding myb-like transcription factor 1 | -0.00521613 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.00521429 |
| SPRR1B | small proline-rich protein 1B | -0.00519645 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | -0.00518819 |
| DIPK1A | divergent protein kinase domain 1A | -0.00515498 |
| GPR87 | G protein-coupled receptor 87 | -0.00514907 |
| DSG3 | desmoglein 3 | -0.00513895 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | -0.00513729 |
| SLC22A18 | solute carrier family 22, member 18 | -0.00513657 |
| HLA-A | major histocompatibility complex, class I, A | -0.00513095 |
| FHL2 | four and a half LIM domains 2 | -0.00512412 |
| UPP1 | uridine phosphorylase 1 | -0.00510494 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.00509554 |
| FCGBP | Fc fragment of IgG binding protein | -0.00509487 |
| RELN | reelin | -0.00508418 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | -0.00507783 |
| TNFRSF9 | tumor necrosis factor receptor superfamily, member 9 | -0.0050674 |
| VGLL4 | vestigial-like family member 4 | -0.00506214 |
| MXRA7 | matrix-remodelling associated 7 | -0.00506177 |
| HECTD3 | HECT domain containing E3 ubiquitin protein ligase 3 | -0.00506082 |
| CSTA | cystatin A (stefin A) | -0.00504178 |
| CARD10 | caspase recruitment domain family, member 10 | -0.00503581 |
| SMPX | small muscle protein, X-linked | -0.00501809 |
