MTNR1A Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description melatonin receptor 1A|This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 4543)
External Link http://www.ncbi.nlm.nih.gov/gene/4543
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27 interacting proteins for MTNR1A from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
CALR calreticulin
CANX calnexin
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
EEF1G eukaryotic translation elongation factor 1 gamma
FLNA filamin A, alpha
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1
GNB4 guanine nucleotide binding protein (G protein), beta polypeptide 4
GPR50 G protein-coupled receptor 50
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
IRS4 insulin receptor substrate 4
LRRC59 leucine rich repeat containing 59
MTNR1B melatonin receptor 1B
PDIA6 protein disulfide isomerase family A, member 6
PGRMC1 progesterone receptor membrane component 1
RAB10 RAB10, member RAS oncogene family
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAP1A RAP1A, member of RAS oncogene family
RGS20 regulator of G-protein signaling 20
TMEM33 transmembrane protein 33
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C