MTNR1B Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description melatonin receptor 1B|This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This gene product is an integral membrane protein that is a G-protein coupled, 7-transmembrane receptor. It is found primarily in the retina and brain although this detection requires RT-PCR. It is thought to participate in light-dependent functions in the retina and may be involved in the neurobiological effects of melatonin. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 4544)
External Link https://ncbi.nlm.nih.gov/gene/4544
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Genes

499 genes differentially expressed following the MTNR1B gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
ADO 2-aminoethanethiol (cysteamine) dioxygenase 0.0284424
RPS4Y1 ribosomal protein S4, Y-linked 1 0.0207238
KDM5D lysine (K)-specific demethylase 5D 0.014835
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.0135623
PRDX2 peroxiredoxin 2 0.0126585
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 0.0123336
LPCAT1 lysophosphatidylcholine acyltransferase 1 0.0119149
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.0118621
KANK2 KN motif and ankyrin repeat domains 2 0.0117665
CD320 CD320 molecule 0.0117554
TAGLN transgelin 0.011398
RRBP1 ribosome binding protein 1 0.0113046
AGR2 anterior gradient 2 0.0110041
EGR2 early growth response 2 0.0109883
CCL4 chemokine (C-C motif) ligand 4 0.0109636
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing 0.0109482
MYH11 myosin, heavy chain 11, smooth muscle 0.0109433
NEFH neurofilament, heavy polypeptide 0.0109248
MLPH melanophilin 0.0109017
GOLGA8A golgin A8 family, member A 0.0107711
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) 0.0107091
NBPF10 neuroblastoma breakpoint family, member 10 0.0106269
FEN1 flap structure-specific endonuclease 1 0.0106217
HMGB3 high mobility group box 3 0.0105688
LMNB2 lamin B2 0.0103962
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 0.0103129
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1) 0.0101929
KRT7 keratin 7, type II 0.0101248
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) 0.0100992
PCDH9 protocadherin 9 0.0100302
SLIT2 slit homolog 2 (Drosophila) 0.00999886
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase 0.00991233
CDK5RAP3 CDK5 regulatory subunit associated protein 3 0.00991
IRAK1 interleukin-1 receptor-associated kinase 1 0.0099083
METRN meteorin, glial cell differentiation regulator 0.00982453
BGN biglycan 0.00978944
LUC7L3 LUC7-like 3 (S. cerevisiae) 0.0097839
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.00978358
ANOS1 anosmin 1 0.00972306
NR2F1 nuclear receptor subfamily 2, group F, member 1 0.00960745
SPRY2 sprouty homolog 2 (Drosophila) 0.00954404
LOXL1 lysyl oxidase-like 1 0.0094911
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) 0.00945388
CSK c-src tyrosine kinase 0.0094314
NDNF neuron-derived neurotrophic factor 0.00933072
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 0.00929528
SORD sorbitol dehydrogenase 0.00926679
GSTT1 glutathione S-transferase theta 1 0.00921637
MAP7 microtubule-associated protein 7 0.00919047
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor 0.00918802
CD81 CD81 molecule 0.00918457
SMAD7 SMAD family member 7 0.00917816
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 0.00917659
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 0.00916979
MSN moesin 0.00911199
GOLM1 golgi membrane protein 1 0.0091091
LIG1 ligase I, DNA, ATP-dependent 0.00909478
LAMA5 laminin, alpha 5 0.00906681
ICMT isoprenylcysteine carboxyl methyltransferase 0.00906136
DACH1 dachshund family transcription factor 1 0.00905278
PRF1 perforin 1 (pore forming protein) 0.00904996
MCM5 minichromosome maintenance complex component 5 0.00903666
ACTC1 actin, alpha, cardiac muscle 1 0.00903573
PRKCZ protein kinase C, zeta 0.0090076
FBLN1 fibulin 1 0.00899176
COL16A1 collagen, type XVI, alpha 1 0.008976
ELN elastin 0.00896155
ABHD2 abhydrolase domain containing 2 0.00894695
TARDBP TAR DNA binding protein 0.00894223
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 0.00891894
LIMCH1 LIM and calponin homology domains 1 0.00891569
APLP2 amyloid beta (A4) precursor-like protein 2 0.00887379
MCM7 minichromosome maintenance complex component 7 0.00886821
EHD3 EH-domain containing 3 0.00884331
EFHD2 EF-hand domain family, member D2 0.00881191
SRRT serrate, RNA effector molecule 0.00878614
FERMT1 fermitin family member 1 0.00872965
APMAP adipocyte plasma membrane associated protein 0.00872118
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.00871936
MICALL2 MICAL-like 2 0.00871426
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 0.00869324
FBP1 fructose-1,6-bisphosphatase 1 0.00867259
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4 0.00862531
PTCH1 patched 1 0.0085853
EML3 echinoderm microtubule associated protein like 3 0.00858519
TIMELESS timeless circadian clock 0.0085673
NELL1 NEL-like 1 (chicken) 0.00855493
TRRAP transformation/transcription domain-associated protein 0.00852079
CTPS1 CTP synthase 1 0.0084132
HMG20B high mobility group 20B 0.00840588
SRSF6 serine/arginine-rich splicing factor 6 0.0083582
CCNL2 cyclin L2 0.00831567
DNMT1 DNA (cytosine-5-)-methyltransferase 1 0.00829167
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 0.00828845
INPPL1 inositol polyphosphate phosphatase-like 1 0.00827727
PDE4A phosphodiesterase 4A, cAMP-specific 0.00827696
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.00825579
SLCO1B3 solute carrier organic anion transporter family, member 1B3 0.00824878
WDR6 WD repeat domain 6 0.00824309
SEC16A SEC16 homolog A (S. cerevisiae) 0.00823992
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.00822051
MCM3 minichromosome maintenance complex component 3 0.00821892
HDAC6 histone deacetylase 6 0.00819312
TGM2 transglutaminase 2 0.00817772
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 0.00816129
SLC39A6 solute carrier family 39 (zinc transporter), member 6 0.0081532
AGRN agrin 0.0081104
INTS1 integrator complex subunit 1 0.00808814
NOTCH2 notch 2 0.00805853
NKG7 natural killer cell granule protein 7 0.00804186
CXCL9 chemokine (C-X-C motif) ligand 9 0.00802919
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 0.00802236
RXRA retinoid X receptor, alpha 0.00801157
NELL2 NEL-like 2 (chicken) 0.00799912
ACSL1 acyl-CoA synthetase long-chain family member 1 0.00797427
TFF3 trefoil factor 3 (intestinal) 0.0079679
SNX1 sorting nexin 1 0.00795936
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5) 0.00794798
ARID1A AT rich interactive domain 1A (SWI-like) 0.00794197
TXLNA taxilin alpha 0.00794107
EIF3B eukaryotic translation initiation factor 3, subunit B 0.007923
ELP1 elongator acetyltransferase complex subunit 1 0.00791352
MLEC malectin 0.00790694
LTBP2 latent transforming growth factor beta binding protein 2 0.00790341
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 0.00790299
IGF1 insulin-like growth factor 1 (somatomedin C) 0.00786931
LGALS1 lectin, galactoside-binding, soluble, 1 0.00786854
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2 0.00785835
SIDT2 SID1 transmembrane family, member 2 0.00785703
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 0.00785413
CD8A CD8a molecule 0.00784128
NBL1 neuroblastoma 1, DAN family BMP antagonist 0.00782675
CCR1 chemokine (C-C motif) receptor 1 0.00781521
TRIP13 thyroid hormone receptor interactor 13 0.00779394
GOLGA8H golgin A8 family, member H 0.00778275
MPRIP myosin phosphatase Rho interacting protein 0.00776969
MXRA5 matrix-remodelling associated 5 0.00776482
RAPSN receptor-associated protein of the synapse 0.00775093
ZWINT ZW10 interacting kinetochore protein 0.00774167
DPY19L1 dpy-19-like 1 (C. elegans) 0.00771698
CPS1 carbamoyl-phosphate synthase 1, mitochondrial 0.00770437
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 0.00769836
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 0.00768673
PDE4D phosphodiesterase 4D, cAMP-specific 0.0076703
PLXNB1 plexin B1 0.00763443
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae) 0.00763184
FASN fatty acid synthase 0.00761824
DVL1 dishevelled segment polarity protein 1 0.00761585
CDC25B cell division cycle 25B 0.00761483
DNM1 dynamin 1 0.00760756
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 0.0075871
ACACA acetyl-CoA carboxylase alpha 0.00758388
DPYSL2 dihydropyrimidinase-like 2 0.00754899
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase 0.0075467
RALGDS ral guanine nucleotide dissociation stimulator 0.00754056
ZDHHC11 zinc finger, DHHC-type containing 11 0.00748649
MYO5C myosin VC 0.00748606
NUMA1 nuclear mitotic apparatus protein 1 0.0074809
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 0.00747221
PGGHG protein-glucosylgalactosylhydroxylysine glucosidase 0.00745794
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.0074548
RNPEP arginyl aminopeptidase (aminopeptidase B) 0.00745475
MMP2 matrix metallopeptidase 2 0.00744564
SSRP1 structure specific recognition protein 1 0.00743863
PLXNA1 plexin A1 0.00743562
FZD2 frizzled class receptor 2 0.00741761
CHD4 chromodomain helicase DNA binding protein 4 0.00740392
S100A4 S100 calcium binding protein A4 0.00740332
KLK2 kallikrein-related peptidase 2 0.00738868
COL7A1 collagen, type VII, alpha 1 0.00738495
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 0.00736919
TMC6 transmembrane channel-like 6 0.00736278
CCNA2 cyclin A2 0.00735951
ADAM22 ADAM metallopeptidase domain 22 0.00735156
KLRK1 killer cell lectin-like receptor subfamily K, member 1 0.00732709
SPATA20 spermatogenesis associated 20 0.00732068
EPHB2 EPH receptor B2 0.00731594
PNPLA6 patatin-like phospholipase domain containing 6 0.00729921
AURKB aurora kinase B 0.00729602
RUSC1 RUN and SH3 domain containing 1 0.00727242
ELAC2 elaC ribonuclease Z 2 0.00725583
MTA1 metastasis associated 1 0.00725032
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.00723525
RBM6 RNA binding motif protein 6 0.00722656
PTP4A2 protein tyrosine phosphatase type IVA, member 2 0.00722474
SYNM synemin, intermediate filament protein 0.00722302
NKX3-1 NK3 homeobox 1 0.00721972
PILRB paired immunoglobin-like type 2 receptor beta 0.00721694
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.00721654
CALCA calcitonin-related polypeptide alpha 0.00720901
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 0.00720549
HNRNPM heterogeneous nuclear ribonucleoprotein M 0.00720201
CHGB chromogranin B 0.00720149
NSD2 nuclear receptor binding SET domain protein 2 0.00720004
EXOC7 exocyst complex component 7 0.00719652
TOP2A topoisomerase (DNA) II alpha 170kDa 0.00719017
FAM50A family with sequence similarity 50, member A 0.00718977
DEGS1 delta(4)-desaturase, sphingolipid 1 0.00718468
COL6A2 collagen, type VI, alpha 2 0.00717957
VPS16 vacuolar protein sorting 16 homolog (S. cerevisiae) 0.00716958
DDAH1 dimethylarginine dimethylaminohydrolase 1 0.00716791
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 0.00713682
SFRP4 secreted frizzled-related protein 4 0.00712123
OLFM4 olfactomedin 4 0.00710808
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 0.00710753
RPA1 replication protein A1, 70kDa 0.00710076
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11 0.00709654
GSTA4 glutathione S-transferase alpha 4 0.00709194
TRPM4 transient receptor potential cation channel, subfamily M, member 4 0.00708348
NDRG3 NDRG family member 3 0.0070749
NR5A1 nuclear receptor subfamily 5, group A, member 1 0.0070592
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.00705262
RERE arginine-glutamic acid dipeptide (RE) repeats 0.00703056
MAGED1 melanoma antigen family D1 0.0070269
PIAS3 protein inhibitor of activated STAT, 3 0.00702107
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial 0.00702042
CHD7 chromodomain helicase DNA binding protein 7 0.00701845
ANXA6 annexin A6 0.00701362
MAN2C1 mannosidase, alpha, class 2C, member 1 0.00701068
ZCCHC24 zinc finger, CCHC domain containing 24 0.0070104
DGKD diacylglycerol kinase, delta 130kDa 0.00699573
TK1 thymidine kinase 1, soluble 0.00698574
ACOT7 acyl-CoA thioesterase 7 0.00697212
MARCKSL1 MARCKS-like 1 0.00696323
NOP56 NOP56 ribonucleoprotein 0.00696159
PWWP3A PWWP domain containing 3A, DNA repair factor 0.00694599
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) 0.00694164
PTN pleiotrophin 0.0069371
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 0.00692405
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3 0.00692152
TUBB4B tubulin, beta 4B class IVb 0.00690759
PGD phosphogluconate dehydrogenase 0.0069054
TBCD tubulin folding cofactor D 0.00690157
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta 0.00689709
CCL19 chemokine (C-C motif) ligand 19 0.00689699
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 0.00687282
RTN3 reticulon 3 0.00686852
ERBB3 erb-b2 receptor tyrosine kinase 3 0.00685865
KHSRP KH-type splicing regulatory protein 0.00685828
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2 0.00685828
SPEN spen family transcriptional repressor 0.00684787
SLCO4A1 solute carrier organic anion transporter family, member 4A1 0.00684671
DPT dermatopontin 0.0068411
PALLD palladin, cytoskeletal associated protein 0.00683066
PLAT plasminogen activator, tissue 0.00683033
BAHCC1 BAH domain and coiled-coil containing 1 0.00682407
FOXM1 forkhead box M1 0.00681831
PTGIS prostaglandin I2 (prostacyclin) synthase 0.00681722
DHX30 DEAH (Asp-Glu-Ala-His) box helicase 30 0.00681637

decreased expression

Symbol Name Standardized Value
HSPB1 heat shock 27kDa protein 1 -0.0297106
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.0217622
ATF3 activating transcription factor 3 -0.0193898
H1-2 H1.2 linker histone, cluster member -0.0150332
EIF5A eukaryotic translation initiation factor 5A -0.0148637
MT1G metallothionein 1G -0.014357
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 -0.0136445
PITX3 paired-like homeodomain 3 -0.0134953
ADM adrenomedullin -0.0133566
PEG3 paternally expressed 3 -0.0132931
TUBB2A tubulin, beta 2A class IIa -0.0130727
MT1X metallothionein 1X -0.0129955
MT1F metallothionein 1F -0.0129545
CLEC2B C-type lectin domain family 2, member B -0.0128998
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.0128733
DDIT3 DNA-damage-inducible transcript 3 -0.0128144
C10ORF10 chromosome 10 open reading frame 10 -0.0128056
BTG3 BTG family, member 3 -0.0127846
CCL20 chemokine (C-C motif) ligand 20 -0.0126373
AK4 adenylate kinase 4 -0.0125888
S100A9 S100 calcium binding protein A9 -0.0120856
MT1E metallothionein 1E -0.0118291
XIC X chromosome inactivation center -0.0117719
MT1HL1 metallothionein 1H-like 1 -0.0116765
MAL mal, T-cell differentiation protein -0.0116729
SCGB2A1 secretoglobin, family 2A, member 1 -0.0116029
EMX2 empty spiracles homeobox 2 -0.0115313
GOLT1B golgi transport 1B -0.0113101
SAT1 spermidine/spermine N1-acetyltransferase 1 -0.0112516
MT1M metallothionein 1M -0.0110592
CA12 carbonic anhydrase XII -0.0110229
MT1H metallothionein 1H -0.0109709
CD59 CD59 molecule, complement regulatory protein -0.010942
PLIN2 perilipin 2 -0.0109052
SGCE sarcoglycan, epsilon -0.0108657
DEFB1 defensin, beta 1 -0.0108611
LPPR4 lipid phosphate phosphatase-related protein type 4 -0.010854
S100A7 S100 calcium binding protein A7 -0.0107467
CLDN8 claudin 8 -0.010716
HIST1H2AC histone cluster 1, H2ac -0.0106786
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 -0.0106582
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) -0.0106415
DLK1 delta-like 1 homolog (Drosophila) -0.0106396
F2RL1 coagulation factor II (thrombin) receptor-like 1 -0.0105089
KLK5 kallikrein-related peptidase 5 -0.0104592
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 -0.0104306
ISG20 interferon stimulated exonuclease gene 20kDa -0.0103762
MT2A metallothionein 2A -0.0103609
DOK5 docking protein 5 -0.0103366
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa -0.0103272
PTP4A1 protein tyrosine phosphatase type IVA, member 1 -0.0102423
UBE2B ubiquitin-conjugating enzyme E2B -0.0102123
HILPDA hypoxia inducible lipid droplet-associated -0.0101786
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5 -0.0101705
PNRC1 proline-rich nuclear receptor coactivator 1 -0.0100524
F3 coagulation factor III (thromboplastin, tissue factor) -0.010021
C1ORF54 chromosome 1 open reading frame 54 -0.00997284
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 -0.00993736
SCN3A sodium channel, voltage gated, type III alpha subunit -0.00989997
MYO1C myosin IC -0.00988882
VAMP5 vesicle-associated membrane protein 5 -0.00987297
SH3GLB1 SH3-domain GRB2-like endophilin B1 -0.00980077
LRRC17 leucine rich repeat containing 17 -0.0097965
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 -0.00977627
TMEM59 transmembrane protein 59 -0.00973586
TFRC transferrin receptor -0.0097075
CA4 carbonic anhydrase IV -0.0097011
DMAC2L distal membrane arm assembly component 2 like -0.00966249
CHI3L2 chitinase 3-like 2 -0.00961635
S100A8 S100 calcium binding protein A8 -0.0096111
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5 -0.0095478
BCAT1 branched chain amino-acid transaminase 1, cytosolic -0.00952537
SLC38A2 solute carrier family 38, member 2 -0.00951636
LIMS1 LIM and senescent cell antigen-like domains 1 -0.00950496
SST somatostatin -0.00948906
ANXA1 annexin A1 -0.00948221
CLCA4 chloride channel accessory 4 -0.0094613
PPP1R15A protein phosphatase 1, regulatory subunit 15A -0.00941071
MS4A12 membrane-spanning 4-domains, subfamily A, member 12 -0.00940189
LOX lysyl oxidase -0.0094017
ERGIC2 ERGIC and golgi 2 -0.00938326
COMMD10 COMM domain containing 10 -0.0093221
PPP1R3C protein phosphatase 1, regulatory subunit 3C -0.00930919
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 -0.00927731
RIPOR2 RHO family interacting cell polarization regulator 2 -0.00925856
LYRM4 LYR motif containing 4 -0.00925816
MRPL18 mitochondrial ribosomal protein L18 -0.00922347
BEX4 brain expressed, X-linked 4 -0.00921909
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) -0.00920837
CST6 cystatin E/M -0.0091982
RPP40 ribonuclease P/MRP 40kDa subunit -0.00919237
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A -0.00919081
TM4SF1 transmembrane 4 L six family member 1 -0.009159
IGFBP5 insulin-like growth factor binding protein 5 -0.00915289
CNN3 calponin 3, acidic -0.00914467
METTL7A methyltransferase like 7A -0.00909638
SCGB1D2 secretoglobin, family 1D, member 2 -0.00909258
CA2 carbonic anhydrase II -0.00908767
CRABP1 cellular retinoic acid binding protein 1 -0.00897228
BCL2A1 BCL2-related protein A1 -0.00897215
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) -0.0089532
LCP1 lymphocyte cytosolic protein 1 (L-plastin) -0.00886483
ATP5F1C ATP synthase F1 subunit gamma -0.00885015
MAP1LC3B microtubule-associated protein 1 light chain 3 beta -0.00883484
LY96 lymphocyte antigen 96 -0.00878366
GSTO1 glutathione S-transferase omega 1 -0.00876167
CCNC cyclin C -0.00872159
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 -0.00871004
PLIN3 perilipin 3 -0.00862354
SLC26A3 solute carrier family 26 (anion exchanger), member 3 -0.00860327
STOM stomatin -0.00860295
LCMT1 leucine carboxyl methyltransferase 1 -0.00858397
PEG10 paternally expressed 10 -0.00856212
ARHGAP15 Rho GTPase activating protein 15 -0.00855575
REEP5 receptor accessory protein 5 -0.00854758
IFI27 interferon, alpha-inducible protein 27 -0.00851624
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) -0.00849667
ELL2 elongation factor, RNA polymerase II, 2 -0.00847712
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 -0.00844476
SSBP2 single-stranded DNA binding protein 2 -0.0084356
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 -0.00839974
MPC1 mitochondrial pyruvate carrier 1 -0.00834101
CLDN10 claudin 10 -0.00834028
ZNF395 zinc finger protein 395 -0.00831916
BIRC3 baculoviral IAP repeat containing 3 -0.00831813
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.00829357
RAP1B RAP1B, member of RAS oncogene family -0.00829003
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein -0.00826763
TRAM1 translocation associated membrane protein 1 -0.0082548
UQCRC2 ubiquinol-cytochrome c reductase core protein II -0.00825025
DHRS9 dehydrogenase/reductase (SDR family) member 9 -0.00822671
ICAM2 intercellular adhesion molecule 2 -0.00822041
AREG amphiregulin -0.00820853
RGS10 regulator of G-protein signaling 10 -0.00819424
CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2 -0.00814137
UBFD1 ubiquitin family domain containing 1 -0.00811268
SLPI secretory leukocyte peptidase inhibitor -0.00809173
KLF9 Kruppel-like factor 9 -0.00807532
PLK1 polo-like kinase 1 -0.0080607
ZG16 zymogen granule protein 16 -0.00805773
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A -0.00803999
PROM1 prominin 1 -0.00802821
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma -0.00802283
MRPL35 mitochondrial ribosomal protein L35 -0.00802245
TSPAN31 tetraspanin 31 -0.0080135
CD34 CD34 molecule -0.00796696
RIPK2 receptor-interacting serine-threonine kinase 2 -0.00796289
TSC22D1 TSC22 domain family, member 1 -0.00795432
NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa -0.00795093
GTF2B general transcription factor IIB -0.00794148
LMO2 LIM domain only 2 (rhombotin-like 1) -0.0079369
AP3S1 adaptor-related protein complex 3, sigma 1 subunit -0.00790732
CGRRF1 cell growth regulator with ring finger domain 1 -0.00787987
MRPL39 mitochondrial ribosomal protein L39 -0.00786836
GAP43 growth associated protein 43 -0.00786165
CRIPT cysteine-rich PDZ-binding protein -0.0078608
RAB1A RAB1A, member RAS oncogene family -0.00784303
GABRP gamma-aminobutyric acid (GABA) A receptor, pi -0.00783773
EAF2 ELL associated factor 2 -0.00783124
COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like -0.00782353
COBLL1 cordon-bleu WH2 repeat protein-like 1 -0.00782326
TMEM140 transmembrane protein 140 -0.00779645
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -0.00779186
CLTB clathrin, light chain B -0.00778635
HIST1H2BD histone cluster 1, H2bd -0.00777154
LEPROT leptin receptor overlapping transcript -0.00776723
ZNF277 zinc finger protein 277 -0.00776488
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) -0.00774568
IL6ST interleukin 6 signal transducer -0.00773788
EIF5 eukaryotic translation initiation factor 5 -0.00773288
SRPRB signal recognition particle receptor, B subunit -0.00771374
GABARAPL2 GABA(A) receptor-associated protein-like 2 -0.00769187
SINHCAF SIN3-HDAC complex associated factor -0.00766159
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) -0.00761618
NUPR1 nuclear protein, transcriptional regulator, 1 -0.00760309
HPGDS hematopoietic prostaglandin D synthase -0.00759633
PIGP phosphatidylinositol glycan anchor biosynthesis, class P -0.00758998
FMO4 flavin containing monooxygenase 4 -0.00758673
MGLL monoglyceride lipase -0.00757653
BID BH3 interacting domain death agonist -0.00757256
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 -0.00757068
EPCAM epithelial cell adhesion molecule -0.00756392
GPRC5B G protein-coupled receptor, class C, group 5, member B -0.00753671
RPS27L ribosomal protein S27-like -0.00752838
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 -0.00752732
SAR1B secretion associated, Ras related GTPase 1B -0.00752663
RAB8B RAB8B, member RAS oncogene family -0.0075136
HSPA2 heat shock 70kDa protein 2 -0.00751254
PELI1 pellino E3 ubiquitin protein ligase 1 -0.00750627
ATF6 activating transcription factor 6 -0.00750493
GRB7 growth factor receptor-bound protein 7 -0.00749316
COQ10B coenzyme Q10 homolog B (S. cerevisiae) -0.00748984
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -0.00747718
DAZAP2 DAZ associated protein 2 -0.00745217
CARMIL1 capping protein regulator and myosin 1 linker 1 -0.00745195
ADD3 adducin 3 (gamma) -0.0074504
EDN3 endothelin 3 -0.00743235
IDS iduronate 2-sulfatase -0.00739648
CYB5R4 cytochrome b5 reductase 4 -0.00738591
ATG5 autophagy related 5 -0.00736941
PNO1 partner of NOB1 homolog (S. cerevisiae) -0.00736453
UFD1 ubiquitin recognition factor in ER associated degradation 1 -0.00734515
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6 -0.00733636
CNIH1 cornichon family AMPA receptor auxiliary protein 1 -0.00731276
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent -0.00728199
YPEL5 yippee-like 5 (Drosophila) -0.00726688
C6ORF48 chromosome 6 open reading frame 48 -0.00724916
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F -0.00724549
MAP3K7CL MAP3K7 C-terminal like -0.00724342
MAN1A1 mannosidase, alpha, class 1A, member 1 -0.00724303
UGP2 UDP-glucose pyrophosphorylase 2 -0.00722899
FABP5 fatty acid binding protein 5 (psoriasis-associated) -0.00722858
DAD1 defender against cell death 1 -0.00722212
ATG3 autophagy related 3 -0.00721452
KLF6 Kruppel-like factor 6 -0.00720479
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -0.00719855
CD164 CD164 molecule, sialomucin -0.00718779
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -0.00715444
SELL selectin L -0.00713169
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) -0.0071165
DAXX death-domain associated protein -0.00711273
ASS1 argininosuccinate synthase 1 -0.00710538
UQCRH ubiquinol-cytochrome c reductase hinge protein -0.00710179
MECOM MDS1 and EVI1 complex locus -0.0070986
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) -0.00709609
STX12 syntaxin 12 -0.00709399
KCMF1 potassium channel modulatory factor 1 -0.00708043
FZD6 frizzled class receptor 6 -0.00706761
ZC3H15 zinc finger CCCH-type containing 15 -0.00704519
RCAN1 regulator of calcineurin 1 -0.0070294
QPRT quinolinate phosphoribosyltransferase -0.00702348
RAB9A RAB9A, member RAS oncogene family -0.00701994
MRS2 MRS2 magnesium transporter -0.0070194
CHIC2 cysteine-rich hydrophobic domain 2 -0.00701873
BTF3P11 basic transcription factor 3 pseudogene 11 -0.00701256
KLK7 kallikrein-related peptidase 7 -0.00699337
ATP5PD ATP synthase peripheral stalk subunit d -0.0069929
KRT23 keratin 23, type I -0.00698487
RGCC regulator of cell cycle -0.00696962
MRPL40 mitochondrial ribosomal protein L40 -0.00696895
RPS14P3 ribosomal protein S14 pseudogene 3 -0.00696441
VAMP8 vesicle-associated membrane protein 8 -0.00695717
MAT2B methionine adenosyltransferase II, beta -0.00695294
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.00693784
CSTA cystatin A (stefin A) -0.0069278
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) -0.00691583
ZNF91 zinc finger protein 91 -0.00691291
SLC25A46 solute carrier family 25, member 46 -0.0069048
RSL1D1 ribosomal L1 domain containing 1 -0.00690247
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 -0.00689751