MTOR Gene Set

Dataset Kinase Library Serine Threonine Kinome Atlas
Category proteomics
Type kinase
Description mechanistic target of rapamycin (serine/threonine kinase)|The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq, Sep 2008] (NCBI Entrez Gene Database, 2475)
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100 substrates of the kinase MTOR from the Kinase Library Serine Threonine Kinome Atlas dataset.

Symbol Name Standardized Value
ZNF696 zinc finger protein 696
MAP7D2 MAP7 domain containing 2
RTN3 reticulon 3
PKP4 plakophilin 4
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
CHAMP1 chromosome alignment maintaining phosphoprotein 1
CTR9 CTR9, Paf1/RNA polymerase II complex component
AKAP12 A kinase (PRKA) anchor protein 12
USP24 ubiquitin specific peptidase 24
ZCCHC8 zinc finger, CCHC domain containing 8
ZCCHC6 zinc finger, CCHC domain containing 6
TBX18 T-box 18
PPP1R10 protein phosphatase 1, regulatory subunit 10
PERM1 PPARGC1 and ESRR induced regulator, muscle 1
GLIS2 GLIS family zinc finger 2
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
METTL2B methyltransferase like 2B
TNS1 tensin 1
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
ASCC2 activating signal cointegrator 1 complex subunit 2
TNFRSF4 tumor necrosis factor receptor superfamily, member 4
PDE3B phosphodiesterase 3B, cGMP-inhibited
ARHGEF19 Rho guanine nucleotide exchange factor (GEF) 19
RBMX RNA binding motif protein, X-linked
BBC3 BCL2 binding component 3
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
HSPA12B heat shock 70kD protein 12B
ANO2 anoctamin 2, calcium activated chloride channel
KLHDC7B kelch domain containing 7B
ADD2 adducin 2 (beta)
ADD1 adducin 1 (alpha)
PRR14L proline rich 14-like
BANP BTG3 associated nuclear protein
YIPF1 Yip1 domain family, member 1
ANKRD13D ankyrin repeat domain 13 family, member D
FOXK2 forkhead box K2
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
SLX4 SLX4 structure-specific endonuclease subunit
PTPRU protein tyrosine phosphatase, receptor type, U
MGC50722 uncharacterized MGC50722
MBD1 methyl-CpG binding domain protein 1
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
UNK unkempt family zinc finger
BRSK1 BR serine/threonine kinase 1
FLJ22184
RSRP1 arginine/serine-rich protein 1
CDK5R2 cyclin-dependent kinase 5, regulatory subunit 2 (p39)
ACAP1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
FBXO46 F-box protein 46
DIAPH1 diaphanous-related formin 1
FAM193B family with sequence similarity 193, member B
ZNF629 zinc finger protein 629
DCLK2 doublecortin-like kinase 2
MPLKIP M-phase specific PLK1 interacting protein
UHRF1 ubiquitin-like with PHD and ring finger domains 1
CDT1 chromatin licensing and DNA replication factor 1
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon
CDCA7 cell division cycle associated 7
MAP7 microtubule-associated protein 7
FGA fibrinogen alpha chain
CAMKK1 calcium/calmodulin-dependent protein kinase kinase 1, alpha
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
SRCIN1 SRC kinase signaling inhibitor 1
RBBP8NL RBBP8 N-terminal like
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3
GSTA1 glutathione S-transferase alpha 1
GSTA2 glutathione S-transferase alpha 2
GSTA3 glutathione S-transferase alpha 3
NCKAP5L NCK-associated protein 5-like
RBMXL1 RNA binding motif protein, X-linked-like 1
ANKLE2 ankyrin repeat and LEM domain containing 2
CIRBP cold inducible RNA binding protein
PSD4 pleckstrin and Sec7 domain containing 4
SEC16A SEC16 homolog A (S. cerevisiae)
CCDC86 coiled-coil domain containing 86
DGKQ diacylglycerol kinase, theta 110kDa
SSH1 slingshot protein phosphatase 1
GEN1 GEN1 Holliday junction 5' flap endonuclease
MYLK myosin light chain kinase
SCAP SREBF chaperone
WIZ widely interspaced zinc finger motifs
NOLC1 nucleolar and coiled-body phosphoprotein 1
JMY junction mediating and regulatory protein, p53 cofactor
METTL2A methyltransferase like 2A
ARHGAP22 Rho GTPase activating protein 22
NSD1 nuclear receptor binding SET domain protein 1
HDLBP high density lipoprotein binding protein
LSR lipolysis stimulated lipoprotein receptor
BAG6 BCL2-associated athanogene 6
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1
CTNND2 catenin (cadherin-associated protein), delta 2
CASC3 cancer susceptibility candidate 3
RPRD1B regulation of nuclear pre-mRNA domain containing 1B
SOBP sine oculis binding protein homolog (Drosophila)
API5 apoptosis inhibitor 5