| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | mechanistic target of rapamycin (serine/threonine kinase)|The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq, Sep 2008] (NCBI Entrez Gene Database, 2475) |
| External Link | https://ncbi.nlm.nih.gov/gene/2475 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the MTOR gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ALCAM | activated leukocyte cell adhesion molecule | 0.0191698 |
| MT1F | metallothionein 1F | 0.0145777 |
| KRT5 | keratin 5, type II | 0.0143567 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0132107 |
| MT1G | metallothionein 1G | 0.0121488 |
| MT1E | metallothionein 1E | 0.0119859 |
| MT1H | metallothionein 1H | 0.0119251 |
| MT1X | metallothionein 1X | 0.0116283 |
| MT1HL1 | metallothionein 1H-like 1 | 0.0114329 |
| KRT14 | keratin 14, type I | 0.0110388 |
| IL1R1 | interleukin 1 receptor, type I | 0.0107226 |
| THBS2 | thrombospondin 2 | 0.0106555 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.0103138 |
| GNAS | GNAS complex locus | 0.0100718 |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) | 0.00990958 |
| SRPX | sushi-repeat containing protein, X-linked | 0.00964618 |
| MX1 | MX dynamin-like GTPase 1 | 0.00963361 |
| TUBA1A | tubulin, alpha 1a | 0.00960773 |
| GPR137B | G protein-coupled receptor 137B | 0.00953106 |
| DEFB1 | defensin, beta 1 | 0.00942827 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0093796 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.00919229 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.00917232 |
| CHEK2 | checkpoint kinase 2 | 0.00895711 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | 0.00894346 |
| LY75 | lymphocyte antigen 75 | 0.00893807 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | 0.00892625 |
| C3 | complement component 3 | 0.00891385 |
| LAMP3 | lysosomal-associated membrane protein 3 | 0.00880206 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0088014 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | 0.00874016 |
| FN1 | fibronectin 1 | 0.00872914 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0086711 |
| MT2A | metallothionein 2A | 0.00865365 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.00864127 |
| NNMT | nicotinamide N-methyltransferase | 0.00856123 |
| CSTA | cystatin A (stefin A) | 0.0085401 |
| MGLL | monoglyceride lipase | 0.00853489 |
| BICC1 | BicC family RNA binding protein 1 | 0.00853089 |
| DIPK1A | divergent protein kinase domain 1A | 0.0085303 |
| KRT6B | keratin 6B, type II | 0.00850165 |
| PUF60 | poly-U binding splicing factor 60KDa | 0.00838891 |
| RUNX3 | runt-related transcription factor 3 | 0.00838186 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.00836392 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 0.00833986 |
| GSTP1 | glutathione S-transferase pi 1 | 0.00829654 |
| VCAN | versican | 0.00826036 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | 0.00824063 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | 0.0081614 |
| KRT6A | keratin 6A, type II | 0.00806576 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.00805778 |
| CES1 | carboxylesterase 1 | 0.00805301 |
| TRIM22 | tripartite motif containing 22 | 0.00785395 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.00785317 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.00784216 |
| LBH | limb bud and heart development | 0.00775779 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.00770679 |
| LAMC2 | laminin, gamma 2 | 0.00756638 |
| LPAR1 | lysophosphatidic acid receptor 1 | 0.00754023 |
| RFTN1 | raftlin, lipid raft linker 1 | 0.00753628 |
| BLNK | B-cell linker | 0.00751377 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.00746855 |
| AHR | aryl hydrocarbon receptor | 0.00746318 |
| TYRP1 | tyrosinase-related protein 1 | 0.00741859 |
| CRIP1 | cysteine-rich protein 1 (intestinal) | 0.00741373 |
| SORBS3 | sorbin and SH3 domain containing 3 | 0.007411 |
| GREM1 | gremlin 1, DAN family BMP antagonist | 0.00739377 |
| C1ORF115 | chromosome 1 open reading frame 115 | 0.00738117 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00736007 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.00732358 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 0.00728765 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.00727567 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | 0.00723877 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | 0.0071915 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0071605 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.00714517 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit | 0.00711373 |
| SLC18A1 | solute carrier family 18 (vesicular monoamine transporter), member 1 | 0.0070973 |
| MSMB | microseminoprotein, beta- | 0.00708471 |
| LAT2 | linker for activation of T cells family, member 2 | 0.00707178 |
| MME | membrane metallo-endopeptidase | 0.00706605 |
| TP63 | tumor protein p63 | 0.00703615 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 0.00702059 |
| GOLGA8H | golgin A8 family, member H | 0.00698946 |
| BGN | biglycan | 0.00696354 |
| SFTPA2 | surfactant protein A2 | 0.00695858 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | 0.0069226 |
| PABPC4 | poly(A) binding protein, cytoplasmic 4 (inducible form) | 0.00692155 |
| CCL21 | chemokine (C-C motif) ligand 21 | 0.0069115 |
| TCF7 | transcription factor 7 (T-cell specific, HMG-box) | 0.00690992 |
| CREB3L1 | cAMP responsive element binding protein 3-like 1 | 0.00686882 |
| ELOVL1 | ELOVL fatty acid elongase 1 | 0.00685406 |
| SRGN | serglycin | 0.00685278 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | 0.00685264 |
| IER5 | immediate early response 5 | 0.00683924 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.00682992 |
| TRIM29 | tripartite motif containing 29 | 0.0068162 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | 0.00675393 |
| PROM1 | prominin 1 | 0.00673069 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | 0.0067195 |
| PBLD | phenazine biosynthesis-like protein domain containing | 0.00669433 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.00669114 |
| SPIB | Spi-B transcription factor (Spi-1/PU.1 related) | 0.00666042 |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 | 0.00664096 |
| SFN | stratifin | 0.00663686 |
| SP110 | SP110 nuclear body protein | 0.00661963 |
| TOR3A | torsin family 3, member A | 0.0066124 |
| CLEC11A | C-type lectin domain family 11, member A | 0.00653961 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.00652651 |
| LMCD1 | LIM and cysteine-rich domains 1 | 0.00652277 |
| SCPEP1 | serine carboxypeptidase 1 | 0.00650228 |
| GPX2 | glutathione peroxidase 2 | 0.00648536 |
| ELF5 | E74-like factor 5 (ets domain transcription factor) | 0.00648136 |
| MRC2 | mannose receptor, C type 2 | 0.00647016 |
| JCHAIN | joining chain of multimeric IgA and IgM | 0.00644502 |
| SFTPC | surfactant protein C | 0.00641812 |
| NDRG2 | NDRG family member 2 | 0.00641168 |
| PDGFC | platelet derived growth factor C | 0.00639504 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | 0.0063871 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | 0.00637868 |
| IPO13 | importin 13 | 0.00636731 |
| CCL19 | chemokine (C-C motif) ligand 19 | 0.00635933 |
| NLRP2 | NLR family, pyrin domain containing 2 | 0.00633772 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | 0.00633391 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.00632586 |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 | 0.00631963 |
| CAST | calpastatin | 0.00631213 |
| ISLR | immunoglobulin superfamily containing leucine-rich repeat | 0.00630941 |
| CYP27A1 | cytochrome P450, family 27, subfamily A, polypeptide 1 | 0.00626195 |
| SFXN3 | sideroflexin 3 | 0.00625886 |
| CALML3 | calmodulin-like 3 | 0.00624153 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.00623417 |
| TLE4 | transducin-like enhancer of split 4 | 0.00623124 |
| ECM1 | extracellular matrix protein 1 | 0.0062308 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.00622898 |
| MMP1 | matrix metallopeptidase 1 | 0.00622494 |
| CCND3 | cyclin D3 | 0.00619718 |
| SIK1 | salt-inducible kinase 1 | 0.00618736 |
| VPS41 | vacuolar protein sorting 41 homolog (S. cerevisiae) | 0.00617768 |
| TRIM8 | tripartite motif containing 8 | 0.00615328 |
| PADI2 | peptidyl arginine deiminase, type II | 0.00614734 |
| LTBP2 | latent transforming growth factor beta binding protein 2 | 0.006147 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | 0.00612652 |
| THBS1 | thrombospondin 1 | 0.00611269 |
| AQP1 | aquaporin 1 (Colton blood group) | 0.00611047 |
| OLFML3 | olfactomedin-like 3 | 0.00610994 |
| FSCN1 | fascin actin-bundling protein 1 | 0.00610546 |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 | 0.00610233 |
| ARHGEF40 | Rho guanine nucleotide exchange factor (GEF) 40 | 0.00607988 |
| TP53I3 | tumor protein p53 inducible protein 3 | 0.00607497 |
| HOPX | HOP homeobox | 0.00604225 |
| ACAA1 | acetyl-CoA acyltransferase 1 | 0.00603678 |
| TSPO | translocator protein (18kDa) | 0.00601503 |
| TGM2 | transglutaminase 2 | 0.00600232 |
| ZMAT3 | zinc finger, matrin-type 3 | 0.00598474 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | 0.00596186 |
| DTX4 | deltex 4, E3 ubiquitin ligase | 0.0059601 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | 0.00594791 |
| CCL22 | chemokine (C-C motif) ligand 22 | 0.0059479 |
| FLT3 | fms-related tyrosine kinase 3 | 0.00594501 |
| XYLT1 | xylosyltransferase I | 0.00594036 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.005933 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 | 0.00591806 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.00591498 |
| MVP | major vault protein | 0.00590689 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.00587167 |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 | 0.00585379 |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 | 0.00584978 |
| CD52 | CD52 molecule | 0.00583305 |
| MXRA5 | matrix-remodelling associated 5 | 0.00581406 |
| RAB29 | RAB29, member RAS oncogene family | 0.00581023 |
| COL5A2 | collagen, type V, alpha 2 | 0.00580455 |
| LXN | latexin | 0.00578049 |
| PTHLH | parathyroid hormone-like hormone | 0.00577117 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | 0.00576176 |
| SLC35E3 | solute carrier family 35, member E3 | 0.00576005 |
| CD81 | CD81 molecule | 0.00575872 |
| SASH1 | SAM and SH3 domain containing 1 | 0.00574478 |
| PRAME | preferentially expressed antigen in melanoma | 0.00574061 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.00573946 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | 0.00572431 |
| GALC | galactosylceramidase | 0.00571922 |
| KLF4 | Kruppel-like factor 4 (gut) | 0.00571378 |
| COPZ2 | coatomer protein complex, subunit zeta 2 | 0.00570651 |
| CDH3 | cadherin 3, type 1, P-cadherin (placental) | 0.00569649 |
| C4BPA | complement component 4 binding protein, alpha | 0.00569326 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | 0.0056648 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 | 0.00566368 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.00563382 |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 | 0.00563295 |
| HEATR1 | HEAT repeat containing 1 | 0.00562402 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.00562067 |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 | 0.00561919 |
| RECK | reversion-inducing-cysteine-rich protein with kazal motifs | 0.00560396 |
| CTSD | cathepsin D | 0.00559275 |
| CH25H | cholesterol 25-hydroxylase | 0.00558787 |
| CLDN5 | claudin 5 | 0.0055801 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.00557861 |
| STC2 | stanniocalcin 2 | 0.00556642 |
| CRABP1 | cellular retinoic acid binding protein 1 | 0.00555528 |
| CA2 | carbonic anhydrase II | 0.00554971 |
| CYB5R2 | cytochrome b5 reductase 2 | 0.00553475 |
| WDR13 | WD repeat domain 13 | 0.00553133 |
| PENK | proenkephalin | 0.00548823 |
| GPX7 | glutathione peroxidase 7 | 0.00544176 |
| RCAN1 | regulator of calcineurin 1 | 0.00541111 |
| FGL1 | fibrinogen-like 1 | 0.00539964 |
| SDC1 | syndecan 1 | 0.0053983 |
| BCAS1 | breast carcinoma amplified sequence 1 | 0.00539335 |
| ANXA1 | annexin A1 | 0.00539183 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.00538855 |
| ARMCX2 | armadillo repeat containing, X-linked 2 | 0.00538749 |
| RTN1 | reticulon 1 | 0.00538555 |
| C1ORF54 | chromosome 1 open reading frame 54 | 0.00537386 |
| IRF6 | interferon regulatory factor 6 | 0.00536318 |
| HOXB2 | homeobox B2 | 0.00535993 |
| PIP4K2C | phosphatidylinositol-5-phosphate 4-kinase, type II, gamma | 0.00535688 |
| COL1A1 | collagen, type I, alpha 1 | 0.0053279 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.00530728 |
| ARPC4 | actin related protein 2/3 complex, subunit 4, 20kDa | 0.00529991 |
| IGSF3 | immunoglobulin superfamily, member 3 | 0.00528457 |
| OXTR | oxytocin receptor | 0.00527778 |
| ACVR2A | activin A receptor, type IIA | 0.00527277 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0052554 |
| FMO4 | flavin containing monooxygenase 4 | 0.00525525 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | 0.00521183 |
| QPCT | glutaminyl-peptide cyclotransferase | 0.00520836 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | 0.00520025 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.00519938 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.00519792 |
| WDTC1 | WD and tetratricopeptide repeats 1 | 0.0051597 |
| EGR3 | early growth response 3 | 0.00514791 |
| SYT17 | synaptotagmin XVII | 0.00514284 |
| TCTN1 | tectonic family member 1 | 0.00513193 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.00512446 |
| ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) | 0.00512097 |
| DNASE1L3 | deoxyribonuclease I-like 3 | 0.00510035 |
| DCT | dopachrome tautomerase | 0.00509891 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | 0.00508553 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.00508484 |
| HSPA1A | heat shock 70kDa protein 1A | 0.0050761 |
| UGT2B15 | UDP glucuronosyltransferase 2 family, polypeptide B15 | 0.00506595 |
| INHBA | inhibin, beta A | 0.00506058 |
| PAMR1 | peptidase domain containing associated with muscle regeneration 1 | 0.00505248 |
| ASRGL1 | asparaginase like 1 | 0.00504414 |
| KRT15 | keratin 15, type I | 0.00504249 |
| NCALD | neurocalcin delta | 0.00503995 |
| PARN | poly(A)-specific ribonuclease | 0.00503795 |
| MYH7B | myosin, heavy chain 7B, cardiac muscle, beta | 0.00503697 |
| Symbol | Name | Standardized Value |
|---|---|---|
| E2F2 | E2F transcription factor 2 | -0.0153762 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | -0.011268 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | -0.0108872 |
| PRDX2 | peroxiredoxin 2 | -0.0105863 |
| S100P | S100 calcium binding protein P | -0.0101574 |
| GLUL | glutamate-ammonia ligase | -0.0100363 |
| IPO5 | importin 5 | -0.00949096 |
| YME1L1 | YME1-like 1 ATPase | -0.00924632 |
| PGAM1 | phosphoglycerate mutase 1 (brain) | -0.00921913 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -0.00901372 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | -0.00864682 |
| ITGA6 | integrin, alpha 6 | -0.00842903 |
| IFRD2 | interferon-related developmental regulator 2 | -0.00835149 |
| SLC39A6 | solute carrier family 39 (zinc transporter), member 6 | -0.00827549 |
| NELL2 | NEL-like 2 (chicken) | -0.00826234 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.00820591 |
| SRSF10 | serine/arginine-rich splicing factor 10 | -0.00817138 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.00801147 |
| SVIL | supervillin | -0.00794927 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0077308 |
| KIF5B | kinesin family member 5B | -0.00768044 |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 | -0.00764689 |
| SELENOT | selenoprotein T | -0.00761836 |
| CALD1 | caldesmon 1 | -0.00754612 |
| CRY1 | cryptochrome circadian clock 1 | -0.00753502 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | -0.00745501 |
| ANXA3 | annexin A3 | -0.00741208 |
| TPM4 | tropomyosin 4 | -0.00728288 |
| CPVL | carboxypeptidase, vitellogenic-like | -0.00724612 |
| SRSF1 | serine/arginine-rich splicing factor 1 | -0.00720888 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.00719455 |
| CCNA2 | cyclin A2 | -0.0071637 |
| CPE | carboxypeptidase E | -0.0071545 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.00715365 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0071366 |
| RCHY1 | ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase | -0.00702907 |
| VSIG4 | V-set and immunoglobulin domain containing 4 | -0.00700212 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | -0.00694536 |
| MYO5C | myosin VC | -0.00692696 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | -0.00685272 |
| FRS2 | fibroblast growth factor receptor substrate 2 | -0.00685115 |
| CLEC2B | C-type lectin domain family 2, member B | -0.00685107 |
| GTPBP8 | GTP-binding protein 8 (putative) | -0.00677943 |
| NNT | nicotinamide nucleotide transhydrogenase | -0.0067576 |
| SUB1 | SUB1 homolog (S. cerevisiae) | -0.00673412 |
| CCNB1 | cyclin B1 | -0.00667681 |
| BMI1 | BMI1 proto-oncogene, polycomb ring finger | -0.00663121 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.00658076 |
| CCL8 | chemokine (C-C motif) ligand 8 | -0.00645962 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.00644832 |
| KLHL23 | kelch-like family member 23 | -0.00638764 |
| TYMS | thymidylate synthetase | -0.00634908 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.00634868 |
| COPS4 | COP9 signalosome subunit 4 | -0.00631986 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.00631311 |
| SRSF7 | serine/arginine-rich splicing factor 7 | -0.00628907 |
| DBF4 | DBF4 zinc finger | -0.00627435 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | -0.00625938 |
| PBK | PDZ binding kinase | -0.00625923 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | -0.00624909 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 | -0.00619158 |
| SRP72 | signal recognition particle 72kDa | -0.00618963 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.00618507 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.00618339 |
| BRD2 | bromodomain containing 2 | -0.00617633 |
| ODC1 | ornithine decarboxylase 1 | -0.00616425 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.00612105 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.00611748 |
| CDA | cytidine deaminase | -0.0061084 |
| SDC2 | syndecan 2 | -0.00609408 |
| MMP12 | matrix metallopeptidase 12 | -0.00607916 |
| PODXL | podocalyxin-like | -0.00607123 |
| CCND2 | cyclin D2 | -0.0060563 |
| RRM2 | ribonucleotide reductase M2 | -0.00601325 |
| EXOC5 | exocyst complex component 5 | -0.00599815 |
| PAXIP1 | PAX interacting (with transcription-activation domain) protein 1 | -0.00598619 |
| PCNA | proliferating cell nuclear antigen | -0.00596468 |
| AIM2 | absent in melanoma 2 | -0.00595475 |
| CTSZ | cathepsin Z | -0.00594843 |
| XIC | X chromosome inactivation center | -0.00594634 |
| CCL14 | chemokine (C-C motif) ligand 14 | -0.00594454 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | -0.00594261 |
| COMMD3 | COMM domain containing 3 | -0.00592044 |
| HMGB1 | high mobility group box 1 | -0.00591961 |
| RAB5C | RAB5C, member RAS oncogene family | -0.00591794 |
| MRPL3 | mitochondrial ribosomal protein L3 | -0.00589842 |
| TMEM106C | transmembrane protein 106C | -0.00589693 |
| PPP4R3A | protein phosphatase 4 regulatory subunit 3A | -0.00586558 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | -0.00584937 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -0.00584745 |
| KIF23 | kinesin family member 23 | -0.00582557 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | -0.00581608 |
| TMEM230 | transmembrane protein 230 | -0.00580114 |
| CAPRIN1 | cell cycle associated protein 1 | -0.00578999 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.00578381 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.00575574 |
| USP34 | ubiquitin specific peptidase 34 | -0.00574438 |
| CLEC5A | C-type lectin domain family 5, member A | -0.00573763 |
| WT1 | Wilms tumor 1 | -0.00573196 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.00572441 |
| ZWILCH | zwilch kinetochore protein | -0.00569692 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.00567554 |
| GSPT1 | G1 to S phase transition 1 | -0.00567027 |
| C4BPB | complement component 4 binding protein, beta | -0.00566574 |
| NDUFB6 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa | -0.0056577 |
| NVL | nuclear VCP-like | -0.00564276 |
| ELP1 | elongator acetyltransferase complex subunit 1 | -0.00563938 |
| CDCA3 | cell division cycle associated 3 | -0.00563289 |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 | -0.00556661 |
| AURKB | aurora kinase B | -0.00556589 |
| ENOPH1 | enolase-phosphatase 1 | -0.00556064 |
| MECOM | MDS1 and EVI1 complex locus | -0.00552197 |
| MAPK14 | mitogen-activated protein kinase 14 | -0.00550883 |
| APOC3 | apolipoprotein C-III | -0.00550114 |
| GPR88 | G protein-coupled receptor 88 | -0.00548458 |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa | -0.00548221 |
| APOBEC3A | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A | -0.00547943 |
| YEATS4 | YEATS domain containing 4 | -0.00547807 |
| CDC42 | cell division cycle 42 | -0.00546181 |
| ST18 | suppression of tumorigenicity 18, zinc finger | -0.00544635 |
| CDKN3 | cyclin-dependent kinase inhibitor 3 | -0.00543466 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | -0.00541529 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | -0.00540758 |
| BAG2 | BCL2-associated athanogene 2 | -0.00540648 |
| NAA15 | N(alpha)-acetyltransferase 15, NatA auxiliary subunit | -0.00539999 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.00535783 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.00534497 |
| SLC38A1 | solute carrier family 38, member 1 | -0.00534406 |
| CCDC86 | coiled-coil domain containing 86 | -0.00534358 |
| COMMD10 | COMM domain containing 10 | -0.00533646 |
| INSM1 | insulinoma-associated 1 | -0.00532737 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.00530702 |
| CUX1 | cut-like homeobox 1 | -0.00530067 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | -0.00529549 |
| NUP205 | nucleoporin 205kDa | -0.00529421 |
| MBNL3 | muscleblind-like splicing regulator 3 | -0.00528071 |
| NBPF10 | neuroblastoma breakpoint family, member 10 | -0.00527051 |
| TOMM22 | translocase of outer mitochondrial membrane 22 homolog (yeast) | -0.00526791 |
| RHOA | ras homolog family member A | -0.00526015 |
| PSMA3 | proteasome (prosome, macropain) subunit, alpha type, 3 | -0.00525001 |
| LRP5 | low density lipoprotein receptor-related protein 5 | -0.00524154 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.00523839 |
| KIF14 | kinesin family member 14 | -0.00522765 |
| MERTK | MER proto-oncogene, tyrosine kinase | -0.00522416 |
| PSRC1 | proline/serine-rich coiled-coil 1 | -0.00521972 |
| PPAT | phosphoribosyl pyrophosphate amidotransferase | -0.00521714 |
| MED21 | mediator complex subunit 21 | -0.00520001 |
| THAP9-AS1 | THAP9 antisense RNA 1 | -0.00519983 |
| PGGHG | protein-glucosylgalactosylhydroxylysine glucosidase | -0.00517218 |
| MED1 | mediator complex subunit 1 | -0.00515158 |
| CD2 | CD2 molecule | -0.0051474 |
| PDSS1 | prenyl (decaprenyl) diphosphate synthase, subunit 1 | -0.00514408 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | -0.00513992 |
| PDCD10 | programmed cell death 10 | -0.00512831 |
| SPC25 | SPC25, NDC80 kinetochore complex component | -0.00509905 |
| TFAM | transcription factor A, mitochondrial | -0.00509763 |
| ITM2A | integral membrane protein 2A | -0.00508625 |
| ANGPT2 | angiopoietin 2 | -0.00508161 |
| NOL11 | nucleolar protein 11 | -0.00506548 |
| SET | SET nuclear proto-oncogene | -0.00506056 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.00505647 |
| SPAG5 | sperm associated antigen 5 | -0.00505021 |
| MCM3AP-AS1 | MCM3AP antisense RNA 1 | -0.00504466 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.00503975 |
| AMDHD2 | amidohydrolase domain containing 2 | -0.00503632 |
| HK2 | hexokinase 2 | -0.00503186 |
| GDE1 | glycerophosphodiester phosphodiesterase 1 | -0.00502125 |
| S100A9 | S100 calcium binding protein A9 | -0.00501089 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | -0.00499036 |
| TXNIP | thioredoxin interacting protein | -0.00498494 |
| RSU1 | Ras suppressor protein 1 | -0.0049838 |
| RNF14 | ring finger protein 14 | -0.00497571 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | -0.00497401 |
| NDC80 | NDC80 kinetochore complex component | -0.00497302 |
| FAM120A | family with sequence similarity 120A | -0.0049707 |
| ME2 | malic enzyme 2, NAD(+)-dependent, mitochondrial | -0.0049692 |
| GLO1 | glyoxalase I | -0.00496514 |
| CITED1 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 | -0.00495025 |
| TMEM135 | transmembrane protein 135 | -0.00494874 |
| MRS2 | MRS2 magnesium transporter | -0.00494191 |
| LPAR6 | lysophosphatidic acid receptor 6 | -0.00494126 |
| ENSA | endosulfine alpha | -0.00493352 |
| IFNG | interferon, gamma | -0.00492085 |
| TFDP1 | transcription factor Dp-1 | -0.00491954 |
| SELENOF | selenoprotein F | -0.00491741 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.00491385 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.00491123 |
| ARMC1 | armadillo repeat containing 1 | -0.00490736 |
| TSPAN6 | tetraspanin 6 | -0.00490722 |
| SSR1 | signal sequence receptor, alpha | -0.00489676 |
| CD163 | CD163 molecule | -0.00489031 |
| ATP6V1B2 | ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 | -0.00488454 |
| ORM1 | orosomucoid 1 | -0.00488355 |
| TLE2 | transducin-like enhancer of split 2 | -0.00487989 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | -0.00487588 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.00486211 |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) | -0.00484864 |
| YIPF5 | Yip1 domain family, member 5 | -0.00484374 |
| DDX39A | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A | -0.00482324 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.00481724 |
| KIF20A | kinesin family member 20A | -0.00481433 |
| FBXO5 | F-box protein 5 | -0.00481255 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | -0.00479338 |
| EEF1E1 | eukaryotic translation elongation factor 1 epsilon 1 | -0.00479132 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.00478732 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | -0.00478419 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -0.00476641 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | -0.00476122 |
| NIP7 | NIP7, nucleolar pre-rRNA processing protein | -0.00475253 |
| NMD3 | NMD3 ribosome export adaptor | -0.00475235 |
| FASTKD3 | FAST kinase domains 3 | -0.00474479 |
| ANKRD17 | ankyrin repeat domain 17 | -0.00474416 |
| HACD1 | 3-hydroxyacyl-CoA dehydratase 1 | -0.00473653 |
| TCERG1 | transcription elongation regulator 1 | -0.00473363 |
| STAM | signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 | -0.00473159 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.00473033 |
| TMEM126B | transmembrane protein 126B | -0.00470573 |
| SON | SON DNA binding protein | -0.00470317 |
| SERPINB8 | serpin peptidase inhibitor, clade B (ovalbumin), member 8 | -0.0046966 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.00468011 |
| RC3H2 | ring finger and CCCH-type domains 2 | -0.00467529 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.00466683 |
| CDC42SE1 | CDC42 small effector 1 | -0.00466271 |
| APOA1 | apolipoprotein A-I | -0.00465949 |
| YOD1 | YOD1 deubiquitinase | -0.00465508 |
| DCTN6 | dynactin 6 | -0.00464787 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0046461 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | -0.00464503 |
| ZMYND11 | zinc finger, MYND-type containing 11 | -0.00464395 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.00464391 |
| CD14 | CD14 molecule | -0.00463045 |
| CRNKL1 | crooked neck pre-mRNA splicing factor 1 | -0.00462804 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | -0.00462578 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | -0.00462422 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | -0.00460905 |
| EPCAM | epithelial cell adhesion molecule | -0.00460248 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.00460037 |
| AIMP1 | aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 | -0.00459009 |
| PDPN | podoplanin | -0.0045854 |
| LCP2 | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) | -0.00458286 |
| RPS6KB1 | ribosomal protein S6 kinase, 70kDa, polypeptide 1 | -0.00457928 |
| PRTN3 | proteinase 3 | -0.00457681 |
| ELAVL1 | ELAV like RNA binding protein 1 | -0.00457384 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit | -0.00456917 |
| NUP54 | nucleoporin 54kDa | -0.00456445 |
| HPCAL1 | hippocalcin-like 1 | -0.00455733 |
| MAPKAPK5-AS1 | MAPKAPK5 antisense RNA 1 | -0.00455617 |
| TARS1 | threonyl-tRNA synthetase 1 | -0.00455029 |
| GCK | glucokinase (hexokinase 4) | -0.00454779 |
| SRSF6 | serine/arginine-rich splicing factor 6 | -0.00454763 |
