MUC3A Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description mucin 3A, cell surface associated|The mucin genes encode epithelial glycoproteins, some of which are secreted and some membrane bound. Each of the genes contains at least one large domain of tandemly repeated sequence that encodes the peptide sequence rich in serine and/or threonine residues, which carries most of the O-linked glycosylation (Gendler and Spicer, 1995 [PubMed 7778880]).[supplied by OMIM, Aug 2008] (NCBI Entrez Gene Database, 4584)
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Genes

368 genes differentially expressed following the MUC3A gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
ZNF534 zinc finger protein 534 2.95812
VAX2 ventral anterior homeobox 2 2.95812
TUBA4B tubulin, alpha 4b 2.95812
TLR5 toll-like receptor 5 2.95812
COL19A1 collagen, type XIX, alpha 1 2.95812
GUCY2D guanylate cyclase 2D, membrane (retina-specific) 2.95812
OCM oncomodulin 2.95812
SLC4A9 solute carrier family 4, sodium bicarbonate cotransporter, member 9 2.95812
TM4SF20 transmembrane 4 L six family member 20 2.95812
SLC39A4 solute carrier family 39 (zinc transporter), member 4 2.95812
RBM46 RNA binding motif protein 46 2.95812
LOC107986837 uncharacterized LOC107986837 2.95812
CALCA calcitonin-related polypeptide alpha 2.95812
FES FES proto-oncogene, tyrosine kinase 2.95812
ALDH3B1 aldehyde dehydrogenase 3 family, member B1 2.95812
GFAP glial fibrillary acidic protein 2.95812
GNLY granulysin 2.95812
PRSS38 protease, serine, 38 2.95812
PSPN persephin 2.95812
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal) 2.95812
FAM167A family with sequence similarity 167, member A 2.95812
SPMIP8 sperm microtubule inner protein 8 2.95812
H4C13 H4 clustered histone 13 2.95812
CCL25 chemokine (C-C motif) ligand 25 2.95812
LINC02798 long intergenic non-protein coding RNA 2798 2.95812
PCDHGA11 protocadherin gamma subfamily A, 11 2.95812
DCST1 DC-STAMP domain containing 1 2.95812
DERPC DERPC proline and glycine rich nuclear protein 2.95812
LCT lactase 2.95812
LRRC55 leucine rich repeat containing 55 2.88505
CARD18 caspase recruitment domain family, member 18 2.88505
DUXB double homeobox B 2.88505
CD19 CD19 molecule 2.88505
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 2.88505
GJB3 gap junction protein, beta 3, 31kDa 2.88505
UNC13C unc-13 homolog C (C. elegans) 2.88505
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 2.88505
GJA10 gap junction protein, alpha 10, 62kDa 2.88505
CTRC chymotrypsin C (caldecrin) 2.88505
PRICKLE4 prickle homolog 4 (Drosophila) 2.88505
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila) 2.88505
IYD iodotyrosine deiodinase 2.88505
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14 2.88505
PAX3 paired box 3 2.88505
EPHX4 epoxide hydrolase 4 2.88505
SLC28A3 solute carrier family 28 (concentrative nucleoside transporter), member 3 2.88505
CPB2 carboxypeptidase B2 (plasma) 2.88505
RLN3 relaxin 3 2.88505
TTLL2 tubulin tyrosine ligase-like family member 2 2.88505
FABP12 fatty acid binding protein 12 2.88505
MAGED4 melanoma antigen family D4 2.88505
CRYGN crystallin, gamma N 2.88505
CORO6 coronin 6 2.88505
ASGR2 asialoglycoprotein receptor 2 2.88505
SH3RF2 SH3 domain containing ring finger 2 2.88505
FSCN3 fascin actin-bundling protein 3, testicular 2.88505
NLRP10 NLR family, pyrin domain containing 10 2.88505
OLIG1 oligodendrocyte transcription factor 1 2.88505
ASB10 ankyrin repeat and SOCS box containing 10 2.88505
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide 2.88505
TNIP3 TNFAIP3 interacting protein 3 2.88505
ARSF arylsulfatase F 2.88505
RFPL2 ret finger protein-like 2 2.88505
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2 2.88505
ADGB androglobin 2.88505
PTGFR prostaglandin F receptor (FP) 2.88505
LVRN laeverin 2.88505
CIMIP1 ciliary microtubule inner protein 1 2.88505
PRDM7 PR domain containing 7 2.88505
ASIC4 acid sensing (proton gated) ion channel family member 4 2.88505
LGSN lengsin, lens protein with glutamine synthetase domain 2.88505
GPR85 G protein-coupled receptor 85 2.88505
FBXO40 F-box protein 40 2.88505
HAL histidine ammonia-lyase 2.88505
ARHGAP15 Rho GTPase activating protein 15 2.88505
BLNK B-cell linker 2.88505
S100B S100 calcium binding protein B 2.88505
PRR4 proline rich 4 (lacrimal) 2.88505
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3 2.88505
LMNTD2 lamin tail domain containing 2 2.88505
SPRR2A small proline-rich protein 2A 2.88505
EPCIP exosomal polycystin 1 interacting protein 2.88505
SYT15B synaptotagmin 15B 2.88505
DEFB109B defensin beta 109B 2.88505
H2BK1 H2B.K variant histone 1 2.88505
TMEM238L transmembrane protein 238 like 2.88505
DNAAF6 dynein axonemal assembly factor 6 2.88505
TAFA3 TAFA chemokine like family member 3 2.88505
MIX23 mitochondrial matrix import factor 23 2.88505
LRRC70 leucine rich repeat containing 70 2.88505
ELFN2 extracellular leucine-rich repeat and fibronectin type III domain containing 2 2.88505
CXCL13 chemokine (C-X-C motif) ligand 13 2.88505
C1QTNF7 C1q and tumor necrosis factor related protein 7 2.88505
MYH15 myosin, heavy chain 15 2.88505
AKAP3 A kinase (PRKA) anchor protein 3 2.88505
ELAC1 elaC ribonuclease Z 1 2.88505
TSSK6 testis-specific serine kinase 6 2.88505
GPR75 G protein-coupled receptor 75 2.88505
SIX1 SIX homeobox 1 2.88505
HRH1 histamine receptor H1 2.88505
COL7A1 collagen, type VII, alpha 1 2.88505
HMGCLL1 3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1 2.88505
ZNF285 zinc finger protein 285 2.88505
INHBB inhibin, beta B 2.88505
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime 2.88505
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6 2.88505
SLC22A11 solute carrier family 22 (organic anion/urate transporter), member 11 2.88505
SCRT2 scratch family zinc finger 2 2.88505
CBLN3 cerebellin 3 precursor 2.88505
LIX1 Lix1 homolog (chicken) 2.88505
DSG1 desmoglein 1 2.88505
ERVFRD-1 endogenous retrovirus group FRD, member 1 2.88505
CLDN5 claudin 5 2.88505
PTPRH protein tyrosine phosphatase, receptor type, H 2.88505
PCDHA3 protocadherin alpha 3 2.88505
LIPF lipase, gastric 2.88505
OR2A1 olfactory receptor, family 2, subfamily A, member 1 2.88505
KLF15 Kruppel-like factor 15 2.88505
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 2.88505
CCDC159 coiled-coil domain containing 159 2.88505
BTNL2 butyrophilin-like 2 2.88505
ANKRD63 ankyrin repeat domain 63 2.88505
CYSLTR1 cysteinyl leukotriene receptor 1 2.88505
NANOGNB NANOG neighbor homeobox 2.88505
C2ORF66 chromosome 2 open reading frame 66 2.88505
GOLGA6B golgin A6 family, member B 2.88505
OAZ3 ornithine decarboxylase antizyme 3 2.88505
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1 2.88505
TBXA2R thromboxane A2 receptor 2.88505
C22ORF42 chromosome 22 open reading frame 42 2.88505
THTPA thiamine triphosphatase 2.88505
S100A14 S100 calcium binding protein A14 2.88505
HSD17B13 hydroxysteroid (17-beta) dehydrogenase 13 2.88505
CTF1 cardiotrophin 1 2.88505
CCL27 chemokine (C-C motif) ligand 27 2.88505
GAGE10 G antigen 10 2.88505
DNAJB13 DnaJ (Hsp40) homolog, subfamily B, member 13 2.88505
SOWAHA sosondowah ankyrin repeat domain family member A 2.88505
TCEA3 transcription elongation factor A (SII), 3 2.88505
RGS13 regulator of G-protein signaling 13 2.88505
LCNL1 lipocalin-like 1 2.88505
LRTM2 leucine-rich repeats and transmembrane domains 2 2.88505
NIPAL4 NIPA-like domain containing 4 2.88505
WNT7B wingless-type MMTV integration site family, member 7B 2.88505
P2RY13 purinergic receptor P2Y, G-protein coupled, 13 2.88505
CCNI2 cyclin I family, member 2 2.88505
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 2.88505
POU4F1 POU class 4 homeobox 1 2.88505
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 2.88505
GJB6 gap junction protein, beta 6, 30kDa 2.88505
FKBP1C FK506 binding protein 1C 2.88505
VMO1 vitelline membrane outer layer 1 homolog (chicken) 2.88505
GOLGA8H golgin A8 family, member H 2.88505
OR52N4 olfactory receptor, family 52, subfamily N, member 4 (gene/pseudogene) 2.88505
MZB1 marginal zone B and B1 cell-specific protein 2.88505
QRFP pyroglutamylated RFamide peptide 2.88505
DND1 DND microRNA-mediated repression inhibitor 1 2.88505
FANCC Fanconi anemia, complementation group C 2.88505
ANKS4B ankyrin repeat and sterile alpha motif domain containing 4B 2.88505
EPGN epithelial mitogen 2.88505
UTS2R urotensin 2 receptor 2.88505
CHIT1 chitinase 1 (chitotriosidase) 2.88505
CALR3 calreticulin 3 2.88505
FGR FGR proto-oncogene, Src family tyrosine kinase 2.88505
ANKRD55 ankyrin repeat domain 55 2.88505
NTN5 netrin 5 2.88505
IP6K3 inositol hexakisphosphate kinase 3 2.88505
CA5A carbonic anhydrase VA, mitochondrial 2.88505
CRTAM cytotoxic and regulatory T cell molecule 2.88505
ASCL3 achaete-scute family bHLH transcription factor 3 2.88505
ABHD1 abhydrolase domain containing 1 2.88505
TBC1D28 TBC1 domain family, member 28 2.88505
ACKR1 atypical chemokine receptor 1 (Duffy blood group) 2.88505
GH2 growth hormone 2 2.88505
RERGL RERG/RAS-like 2.88505
APOL1 apolipoprotein L, 1 2.88505
RHAG Rh-associated glycoprotein 2.88505
CDC26 cell division cycle 26 2.88505
CD22 CD22 molecule 2.88505
ASAH2 N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2 2.88505
TEX38 testis expressed 38 2.88505
ADRA1B adrenoceptor alpha 1B 2.88505
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1 2.88505
PADI3 peptidyl arginine deiminase, type III 2.88505
ZC3H11B zinc finger CCCH-type containing 11B pseudogene 2.88505
ANGPTL3 angiopoietin-like 3 2.88505
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 2.88505
KRTAP13-4 keratin associated protein 13-4 2.88505
ACSM4 acyl-CoA synthetase medium-chain family member 4 2.88505
PCDHGB2 protocadherin gamma subfamily B, 2 2.88505
MANF mesencephalic astrocyte-derived neurotrophic factor 2.88505
TDO2 tryptophan 2,3-dioxygenase 2.88505
UPP2 uridine phosphorylase 2 2.88505
EBF4 early B-cell factor 4 2.88505
ERMN ermin, ERM-like protein 2.88505
FGF4 fibroblast growth factor 4 2.88505
LALBA lactalbumin, alpha- 2.88505
FGF7 fibroblast growth factor 7 2.88505
CALB2 calbindin 2 2.85659
SLC14A2 solute carrier family 14 (urea transporter), member 2 2.75643
INSL3 insulin-like 3 (Leydig cell) 2.75643
FSTL3 follistatin-like 3 (secreted glycoprotein) 2.75643
POU6F2 POU class 6 homeobox 2 2.7489
CD200 CD200 molecule 2.67974
KIAA0586 KIAA0586 2.66313
HEPH hephaestin 2.65296
CTNNA3 catenin (cadherin-associated protein), alpha 3 2.62366
PTTG1 pituitary tumor-transforming 1 2.61515
CCDC121 coiled-coil domain containing 121 2.61428
TRIM73 tripartite motif containing 73 2.61428
RPUSD4 RNA pseudouridylate synthase domain containing 4 2.58142
FOCAD focadhesin 2.58015
COPS7B COP9 signalosome subunit 7B 2.5733
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 2.55797
NAF1 nuclear assembly factor 1 ribonucleoprotein 2.55643
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha 2.53727
TTYH3 tweety family member 3 2.52867
POU6F1 POU class 6 homeobox 1 2.51979
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2 2.50645
GPR143 G protein-coupled receptor 143 2.46895
CDC6 cell division cycle 6 2.44827
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 2.44827
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 2.4283
CIAO2B cytosolic iron-sulfur assembly component 2B 2.40757
PKP4 plakophilin 4 2.4031
PPP1R3F protein phosphatase 1, regulatory subunit 3F 2.3989
PHF8 PHD finger protein 8 2.39197
CLN5 ceroid-lipofuscinosis, neuronal 5 2.32803
NTNG2 netrin G2 2.32634
STRIT1 small transmembrane regulator of ion transport 1 2.32634
PFKL phosphofructokinase, liver 2.32402
ARMH4 armadillo like helical domain containing 4 2.3138
RUMY4 RUMY family member 4 2.26237
ZNF658 zinc finger protein 658 2.26237
PRTFDC1 phosphoribosyl transferase domain containing 1 2.24657
CLGN calmegin 2.22575
P4HA3 prolyl 4-hydroxylase, alpha polypeptide III 2.22395
STMN2 stathmin 2 2.22346
TMEM269 transmembrane protein 269 2.16603
NUP54 nucleoporin 54kDa 2.13025
CCNB2 cyclin B2 2.1118
AGTRAP angiotensin II receptor-associated protein 2.1118
RNF149 ring finger protein 149 2.08712
MRPS26 mitochondrial ribosomal protein S26 2.07684
QTMAN queuosine-tRNA mannosyltransferase 2.05375
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1 2.05375
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) 2.05375
XAB2 XPA binding protein 2 2.04992
SSB Sjogren syndrome antigen B (autoantigen La) 2.04897
KCNK1 potassium channel, two pore domain subfamily K, member 1 2.02967
PALM2AKAP2 PALM2 and AKAP2 fusion 2.01435
CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C) 2.00941

decreased expression

Symbol Name Standardized Value
FNDC4 fibronectin type III domain containing 4 -2.95812
ANKFN1 ankyrin-repeat and fibronectin type III domain containing 1 -2.95812
KIRREL2 kin of IRRE like 2 (Drosophila) -2.95812
TFCP2L1 transcription factor CP2-like 1 -2.95812
LRATD1 LRAT domain containing 1 -2.95812
ZFP57 ZFP57 zinc finger protein -2.95812
ADRA1D adrenoceptor alpha 1D -2.95812
SPATA32 spermatogenesis associated 32 -2.95812
SPDYE21 speedy/RINGO cell cycle regulator family member E21 -2.95812
ART3 ADP-ribosyltransferase 3 -2.95812
ARMC12 armadillo repeat containing 12 -2.88505
SLC44A4 solute carrier family 44, member 4 -2.88505
PDE4C phosphodiesterase 4C, cAMP-specific -2.88505
TMCO6 transmembrane and coiled-coil domains 6 -2.88505
C1ORF167 chromosome 1 open reading frame 167 -2.88505
LKAAEAR1 LKAAEAR motif containing 1 -2.88505
SCN3B sodium channel, voltage gated, type III beta subunit -2.88505
EPC1 enhancer of polycomb homolog 1 (Drosophila) -2.88505
MST1R macrophage stimulating 1 receptor -2.88505
SHISA7 shisa family member 7 -2.88505
SLC5A11 solute carrier family 5 (sodium/inositol cotransporter), member 11 -2.88505
ARSD arylsulfatase D -2.88505
ZNF491 zinc finger protein 491 -2.88505
WTIP Wilms tumor 1 interacting protein -2.88505
CHADL chondroadherin-like -2.88505
ATG9B autophagy related 9B -2.88505
PNMA6A paraneoplastic Ma antigen family member 6A -2.88505
GRHL1 grainyhead-like 1 (Drosophila) -2.88505
ERN2 endoplasmic reticulum to nucleus signaling 2 -2.88505
CCDC62 coiled-coil domain containing 62 -2.88505
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) -2.88505
TCL1B T-cell leukemia/lymphoma 1B -2.88505
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) -2.88505
C1ORF87 chromosome 1 open reading frame 87 -2.88505
TAL2 T-cell acute lymphocytic leukemia 2 -2.88505
FUNDC1 FUN14 domain containing 1 -2.88505
NAP1L5 nucleosome assembly protein 1-like 5 -2.88505
LYG1 lysozyme G-like 1 -2.88505
DCLK3 doublecortin-like kinase 3 -2.88505
C11ORF16 chromosome 11 open reading frame 16 -2.88505
CLEC4C C-type lectin domain family 4, member C -2.88505
MUC16 mucin 16, cell surface associated -2.88505
ANTXR2 anthrax toxin receptor 2 -2.88505
NLRP7 NLR family, pyrin domain containing 7 -2.88505
DCP2 decapping mRNA 2 -2.88505
MARK1 MAP/microtubule affinity-regulating kinase 1 -2.88505
CCDC191 coiled-coil domain containing 191 -2.88505
INSYN2B inhibitory synaptic factor family member 2B -2.88505
CXORF58 chromosome X open reading frame 58 -2.88505
GDPGP1 GDP-D-glucose phosphorylase 1 -2.88505
ADGRA2 adhesion G protein-coupled receptor A2 -2.88505
MSLN mesothelin -2.88505
IGFBP3 insulin-like growth factor binding protein 3 -2.88505
JCAD junctional cadherin 5 associated -2.88505
MINAR1 membrane integral NOTCH2 associated receptor 1 -2.88505
CLIC2 chloride intracellular channel 2 -2.88505
KRTAP5-11 keratin associated protein 5-11 -2.88505
RGS2 regulator of G-protein signaling 2 -2.82275
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa -2.76669
LYPLA1 lysophospholipase I -2.73586
DERL3 derlin 3 -2.69879
MTRF1L mitochondrial translational release factor 1-like -2.67974
LRRC8E leucine rich repeat containing 8 family, member E -2.67974
EXOC3L2 exocyst complex component 3-like 2 -2.67974
OXLD1 oxidoreductase-like domain containing 1 -2.67411
PNISR PNN-interacting serine/arginine-rich protein -2.58142
PPP4R3B protein phosphatase 4 regulatory subunit 3B -2.572
CSKMT citrate synthase lysine methyltransferase -2.54527
PUS7 pseudouridylate synthase 7 (putative) -2.53704
RIPK2 receptor-interacting serine-threonine kinase 2 -2.51558
B2M beta-2-microglobulin -2.50824
PRUNE1 prune exopolyphosphatase 1 -2.49735
RBM47 RNA binding motif protein 47 -2.4759
IFIH1 interferon induced with helicase C domain 1 -2.46927
SMIM15 small integral membrane protein 15 -2.46927
ANGPT1 angiopoietin 1 -2.46895
MAT1A methionine adenosyltransferase I, alpha -2.43877
TTC9 tetratricopeptide repeat domain 9 -2.43633
SMC2 structural maintenance of chromosomes 2 -2.40757
C4ORF36 chromosome 4 open reading frame 36 -2.39197
ABHD17A abhydrolase domain containing 17A -2.34009
COL4A2 collagen, type IV, alpha 2 -2.32634
SOCS3 suppressor of cytokine signaling 3 -2.3138
KCNB2 potassium channel, voltage gated Shab related subfamily B, member 2 -2.3138
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha -2.29689
SLC38A12 solute carrier family 38 member 12 -2.29526
MANEA mannosidase, endo-alpha -2.27664
PRXL2B peroxiredoxin like 2B -2.25305
GFOD1 glucose-fructose oxidoreductase domain containing 1 -2.25191
CCDC71 coiled-coil domain containing 71 -2.24657
SIK1 salt-inducible kinase 1 -2.2315
SFXN5 sideroflexin 5 -2.22391
MAGT1 magnesium transporter 1 -2.20952
SNORC secondary ossification center associated regulator of chondrocyte maturation -2.19081
FN1 fibronectin 1 -2.1865
ZNF177 zinc finger protein 177 -2.18606
PGAP3 post-GPI attachment to proteins 3 -2.17967
CLSTN2 calsyntenin 2 -2.17195
STYK1 serine/threonine/tyrosine kinase 1 -2.17195
POLB polymerase (DNA directed), beta -2.17136
PHF19 PHD finger protein 19 -2.17136
ZNG1E Zn regulated GTPase metalloprotein activator 1E -2.17049
MARCHF1 membrane associated ring-CH-type finger 1 -2.1214
CMTM1 CKLF-like MARVEL transmembrane domain containing 1 -2.1118
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) -2.11092
CPNE4 copine IV -2.09655
DPY19L2 dpy-19-like 2 (C. elegans) -2.07911
TBXAS1 thromboxane A synthase 1 (platelet) -2.07695
BCAT1 branched chain amino-acid transaminase 1, cytosolic -2.07684
C1ORF122 chromosome 1 open reading frame 122 -2.07609
DNAAF5 dynein, axonemal, assembly factor 5 -2.06875
PCSK6 proprotein convertase subtilisin/kexin type 6 -2.0499
SNRPE small nuclear ribonucleoprotein polypeptide E -2.04145
PPP1R13L protein phosphatase 1, regulatory subunit 13 like -2.0234
SH3BP5 SH3-domain binding protein 5 (BTK-associated) -2.01435
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2 -2.01435