MUS81 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description MUS81 structure-specific endonuclease subunit| (NCBI Entrez Gene Database, 80198)
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Genes

352 genes differentially expressed following the MUS81 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
LOC122526780 uncharacterized LOC122526780 4.14931
TRIM74 tripartite motif containing 74 4.14931
TP63 tumor protein p63 4.14931
TRPM1 transient receptor potential cation channel, subfamily M, member 1 4.14931
STX11 syntaxin 11 4.14931
HTR3E 5-hydroxytryptamine (serotonin) receptor 3E, ionotropic 4.14931
CLEC9A C-type lectin domain family 9, member A 4.14931
ITK IL2-inducible T-cell kinase 4.14931
LY96 lymphocyte antigen 96 4.14931
GLUD2 glutamate dehydrogenase 2 4.14931
SVOP SV2 related protein homolog (rat) 4.14931
KISS1 KiSS-1 metastasis-suppressor 4.14931
FGF22 fibroblast growth factor 22 4.14931
OR2A12 olfactory receptor, family 2, subfamily A, member 12 4.14931
MT1M metallothionein 1M 4.14931
PLB1 phospholipase B1 4.14931
MAMDC4 MAM domain containing 4 4.14931
ALKAL1 ALK and LTK ligand 1 4.14931
ASGR2 asialoglycoprotein receptor 2 4.14931
TNR tenascin R 4.14931
COL19A1 collagen, type XIX, alpha 1 4.14931
PRSS54 protease, serine, 54 4.14931
C2ORF78 chromosome 2 open reading frame 78 4.14931
NIBAN3 niban apoptosis regulator 3 4.14931
HNF4A hepatocyte nuclear factor 4, alpha 4.14931
DPEP2 dipeptidase 2 4.13617
PCDHB1 protocadherin beta 1 4.13617
TM4SF20 transmembrane 4 L six family member 20 4.13617
OR2B6 olfactory receptor, family 2, subfamily B, member 6 4.13617
PRSS41 protease, serine, 41 4.13617
PDYN prodynorphin 4.13617
UCN urocortin 4.13617
SLC26A1 solute carrier family 26 (anion exchanger), member 1 4.13617
ADGRE1 adhesion G protein-coupled receptor E1 4.13617
PTPRH protein tyrosine phosphatase, receptor type, H 4.13617
XAF1 XIAP associated factor 1 4.13617
LRRTM2 leucine rich repeat transmembrane neuronal 2 4.13617
DNASE1L3 deoxyribonuclease I-like 3 4.13617
MGAM2 maltase-glucoamylase 2 (putative) 4.13617
PDZD9 PDZ domain containing 9 4.13617
CCL3 chemokine (C-C motif) ligand 3 4.13617
TM4SF1 transmembrane 4 L six family member 1 4.13617
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2 4.13617
DLX4 distal-less homeobox 4 4.13617
DLL4 delta-like 4 (Drosophila) 4.13617
RIMBP3C RIMS binding protein 3C 4.13617
PNOC prepronociceptin 4.13617
NPIPA3 nuclear pore complex interacting protein family, member A3 4.13617
GNRHR gonadotropin-releasing hormone receptor 4.13617
HBZ hemoglobin, zeta 4.13617
LGALS2 lectin, galactoside-binding, soluble, 2 4.13617
MGARP mitochondria-localized glutamic acid-rich protein 4.13617
CACNG1 calcium channel, voltage-dependent, gamma subunit 1 4.13617
BAAT bile acid CoA:amino acid N-acyltransferase 4.13617
HBA1 hemoglobin, alpha 1 4.13617
GFAP glial fibrillary acidic protein 4.13617
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 4.13617
SIGLEC9 sialic acid binding Ig-like lectin 9 4.13617
OPRL1 opiate receptor-like 1 4.13617
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18 4.13617
BIRC7 baculoviral IAP repeat containing 7 4.13617
PTGFR prostaglandin F receptor (FP) 4.13617
GCKR glucokinase (hexokinase 4) regulator 4.13617
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 4.13617
MRC1 mannose receptor, C type 1 4.13617
MUCL3 mucin like 3 4.13617
CD300LF CD300 molecule-like family member f 4.13617
BNC1 basonuclin 1 4.13617
APOBEC3H apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H 4.13617
GC group-specific component (vitamin D binding protein) 4.13617
DOK2 docking protein 2, 56kDa 4.13617
ZNF441 zinc finger protein 441 4.13617
KHDC1L KH homology domain containing 1-like 4.13617
FAM228A family with sequence similarity 228, member A 4.13617
CSAG2 CSAG family, member 2 4.13617
YPEL4 yippee-like 4 (Drosophila) 4.13617
RAG1 recombination activating gene 1 4.13617
TEX13C TEX13 family member C 4.13617
ELOA2 elongin A2 4.13617
TEKTIP1 tektin bundle interacting protein 1 4.13617
JAML junction adhesion molecule like 4.13617
G6PC1 glucose-6-phosphatase catalytic subunit 1 4.13617
CCDC198 coiled-coil domain containing 198 4.13617
GGTA1 glycoprotein alpha-galactosyltransferase 1 (inactive) 4.13617
ANGPTL8 angiopoietin like 8 4.13617
H1-6 H1.6 linker histone, cluster member 4.13617
NDP Norrie disease (pseudoglioma) 4.13617
PRG3 proteoglycan 3 4.13617
GDF9 growth differentiation factor 9 4.13617
CHRD chordin 4.13617
MAGEB1 melanoma antigen family B1 4.13617
TUBA3D tubulin, alpha 3d 4.13617
PCDHB11 protocadherin beta 11 4.13617
ZNF726 zinc finger protein 726 4.13617
OR2A1 olfactory receptor, family 2, subfamily A, member 1 4.13617
KLF17 Kruppel-like factor 17 4.13617
TMEM212 transmembrane protein 212 4.13617
COL20A1 collagen, type XX, alpha 1 4.13617
SLC22A25 solute carrier family 22, member 25 4.13617
C10ORF67 chromosome 10 open reading frame 67 4.13617
FGFBP2 fibroblast growth factor binding protein 2 4.13617
C7 complement component 7 4.13617
PGLYRP2 peptidoglycan recognition protein 2 4.13617
CCR3 chemokine (C-C motif) receptor 3 4.13617
PRR18 proline rich 18 4.13617
CREB3L3 cAMP responsive element binding protein 3-like 3 4.13617
IL6 interleukin 6 4.13617
HAPLN2 hyaluronan and proteoglycan link protein 2 4.13617
C1ORF162 chromosome 1 open reading frame 162 4.13617
RASL10A RAS-like, family 10, member A 4.13617
OR9Q1 olfactory receptor, family 9, subfamily Q, member 1 4.13617
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1 4.13617
MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 4.13617
NNMT nicotinamide N-methyltransferase 4.13617
LCNL1 lipocalin-like 1 4.13617
SPNS3 spinster homolog 3 (Drosophila) 4.13617
KLHL1 kelch-like family member 1 4.13617
SLX1A SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae) 4.13617
OR10G3 olfactory receptor, family 10, subfamily G, member 3 4.13617
HEPACAM hepatic and glial cell adhesion molecule 4.13617
LCN8 lipocalin 8 4.13617
LCN1 lipocalin 1 4.13617
JSRP1 junctional sarcoplasmic reticulum protein 1 4.13617
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 4.13617
NPBWR1 neuropeptides B/W receptor 1 4.13617
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) 4.13617
TCEA3 transcription elongation factor A (SII), 3 4.13617
AQP1 aquaporin 1 (Colton blood group) 4.13617
DES desmin 4.13617
CIDEA cell death-inducing DFFA-like effector a 4.13617
A3GALT2 alpha 1,3-galactosyltransferase 2 4.13617
LRRC43 leucine rich repeat containing 43 4.13617
TMEM132E transmembrane protein 132E 4.13617
AGR2 anterior gradient 2 4.13617
TMIGD3 transmembrane and immunoglobulin domain containing 3 4.13617
KCNK7 potassium channel, two pore domain subfamily K, member 7 4.13617
C9ORF50 chromosome 9 open reading frame 50 4.13617
POU3F2 POU class 3 homeobox 2 4.13617
SLC7A4 solute carrier family 7, member 4 4.13617
MR1 major histocompatibility complex, class I-related 4.13617
PPEF2 protein phosphatase, EF-hand calcium binding domain 2 4.13617
FGF10 fibroblast growth factor 10 4.13617
DKK2 dickkopf WNT signaling pathway inhibitor 2 4.13617
CLEC4D C-type lectin domain family 4, member D 4.13617
LYPD5 LY6/PLAUR domain containing 5 4.13617
MOS v-mos Moloney murine sarcoma viral oncogene homolog 4.13617
LRRC25 leucine rich repeat containing 25 4.13617
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 4.13617
ABCA6 ATP-binding cassette, sub-family A (ABC1), member 6 4.13617
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 4.13617
TPPP tubulin polymerization promoting protein 4.13617
HAGH hydroxyacylglutathione hydrolase 4.13617
PPP1R27 protein phosphatase 1, regulatory subunit 27 4.13617
CXORF58 chromosome X open reading frame 58 4.13617
GOLGA8R golgin A8 family, member R 4.13617
VCX variable charge, X-linked 4.13617
SLC36A3 solute carrier family 36, member 3 4.13617
CLEC14A C-type lectin domain family 14, member A 4.13617
DND1 DND microRNA-mediated repression inhibitor 1 4.13617
PCDHGB2 protocadherin gamma subfamily B, 2 4.13617
PNLIP pancreatic lipase 4.13617
IRX1 iroquois homeobox 1 4.13617
RANBP3L RAN binding protein 3-like 4.13617
DRC5 dynein regulatory complex subunit 5 4.13617
KLK15 kallikrein-related peptidase 15 4.13617
FBXO40 F-box protein 40 4.13617
MEIG1 meiosis/spermiogenesis associated 1 4.13617
SPEF1 sperm flagellar 1 4.13617
ITGB7 integrin, beta 7 4.13617
DMRT1 doublesex and mab-3 related transcription factor 1 4.13617
DHRS9 dehydrogenase/reductase (SDR family) member 9 4.13617
CDH17 cadherin 17, LI cadherin (liver-intestine) 4.13617
SYNGR4 synaptogyrin 4 4.13617
KRTAP4-3 keratin associated protein 4-3 4.13617
IRX4 iroquois homeobox 4 4.13617
DENND5B DENN/MADD domain containing 5B 4.12809
KCTD19 potassium channel tetramerization domain containing 19 4.11094
NOS2 nitric oxide synthase 2, inducible 4.11094
UBE2H ubiquitin-conjugating enzyme E2H 3.20355
CLINT1 clathrin interactor 1 3.14516
UNC5CL unc-5 homolog C (C. elegans)-like 3.06364
SMCO2 single-pass membrane protein with coiled-coil domains 2 3.06364
MLIP muscular LMNA-interacting protein 3.06364
EGFL6 EGF-like-domain, multiple 6 3.06364
IL23A interleukin 23, alpha subunit p19 3.06364
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 3.06364
LINC02798 long intergenic non-protein coding RNA 2798 3.06364
CLC Charcot-Leyden crystal galectin 3.06364
STX19 syntaxin 19 3.06364
GARIN2 golgi associated RAB2 interactor family member 2 3.06364
BTG1 B-cell translocation gene 1, anti-proliferative 3.0564
NCLN nicalin 3.00965
TACC1 transforming, acidic coiled-coil containing protein 1 2.96114
SKIC2 SKI2 subunit of superkiller complex 2.84638
SPOUT1 SPOUT domain containing methyltransferase 1 2.84488
WNT9A wingless-type MMTV integration site family, member 9A 2.76818
FKBP4 FK506 binding protein 4, 59kDa 2.71223
ICE2 interactor of little elongation complex ELL subunit 2 2.63995
SPAG17 sperm associated antigen 17 2.59431
NAALADL1 N-acetylated alpha-linked acidic dipeptidase-like 1 2.57675
ZNF766 zinc finger protein 766 2.57675
GPR27 G protein-coupled receptor 27 2.57609
RNF138 ring finger protein 138, E3 ubiquitin protein ligase 2.56975
HS1BP3 HCLS1 binding protein 3 2.56766
TRMT112 tRNA methyltransferase 11-2 homolog (S. cerevisiae) 2.56457
TSPAN10 tetraspanin 10 2.52279
POU6F1 POU class 6 homeobox 1 2.50449
RCN2 reticulocalbin 2, EF-hand calcium binding domain 2.45756
IFNLR1 interferon, lambda receptor 1 2.44774
BCL7B B-cell CLL/lymphoma 7B 2.44102
GRM5 glutamate receptor, metabotropic 5 2.42717
WDR74 WD repeat domain 74 2.3957
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 2.38843
DAW1 dynein assembly factor with WDR repeat domains 1 2.38843
CCDC152 coiled-coil domain containing 152 2.38843
RTEL1 regulator of telomere elongation helicase 1 2.388
ESCO2 establishment of sister chromatid cohesion N-acetyltransferase 2 2.35104
SHC2 SHC (Src homology 2 domain containing) transforming protein 2 2.34776
POLR2M polymerase (RNA) II (DNA directed) polypeptide M 2.33787
CRYL1 crystallin, lambda 1 2.32844
FXYD2 FXYD domain containing ion transport regulator 2 2.32238
AMER2 APC membrane recruitment protein 2 2.32238
TOMM5 translocase of outer mitochondrial membrane 5 homolog (yeast) 2.32238
VEPH1 ventricular zone expressed PH domain-containing 1 2.31816
CRLS1 cardiolipin synthase 1 2.31403
C15ORF40 chromosome 15 open reading frame 40 2.29768
SEC14L2 SEC14-like 2 (S. cerevisiae) 2.26999
SMOC2 SPARC related modular calcium binding 2 2.24446
EIF1AX eukaryotic translation initiation factor 1A, X-linked 2.21869
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like 2.21855
CFLAR CASP8 and FADD-like apoptosis regulator 2.20233
LHFPL6 LHFPL tetraspan subfamily member 6 2.16815
KLHDC4 kelch domain containing 4 2.16382
TENM1 teneurin transmembrane protein 1 2.15109
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9) 2.07055
C1ORF35 chromosome 1 open reading frame 35 2.06486
FH fumarate hydratase 2.06486
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6 2.03361
BIRC2 baculoviral IAP repeat containing 2 2.02737
APP-DT APP divergent transcript 2.02504
ZC3H15 zinc finger CCCH-type containing 15 2.02504
NLRX1 NLR family member X1 2.02504
DPM2 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit 2.02504
DPP8 dipeptidyl-peptidase 8 2.01732

decreased expression

Symbol Name Standardized Value
PHYHIPL phytanoyl-CoA 2-hydroxylase interacting protein-like -4.14931
ADM5 adrenomedullin 5 (putative) -4.14931
CCDC183 coiled-coil domain containing 183 -4.14931
ATAD3C ATPase family, AAA domain containing 3C -4.14931
GPATCH11 G patch domain containing 11 -4.13617
CHRM1 cholinergic receptor, muscarinic 1 -4.12809
F7 coagulation factor VII (serum prothrombin conversion accelerator) -4.12809
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 -4.12809
VSTM2A V-set and transmembrane domain containing 2A -4.12809
ASPA aspartoacylase -4.12809
ETV2 ets variant 2 -4.12809
LRRC63 leucine rich repeat containing 63 -4.12809
MMP26 matrix metallopeptidase 26 -4.12809
TSHZ1 teashirt zinc finger homeobox 1 -4.12809
OVCH1 ovochymase 1 -4.12809
NWD1 NACHT and WD repeat domain containing 1 -4.12809
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -4.12809
ALDH8A1 aldehyde dehydrogenase 8 family, member A1 -4.12809
UPK3A uroplakin 3A -4.12809
H4C12 H4 clustered histone 12 -4.12809
CCDC178 coiled-coil domain containing 178 -4.12809
OSTN osteocrin -4.12809
ZFP92 ZFP92 zinc finger protein -4.12809
PPP1R14C protein phosphatase 1, regulatory (inhibitor) subunit 14C -4.12809
C2CD4D C2 calcium-dependent domain containing 4D -4.12809
SEPTIN4 septin 4 -4.03606
RBP5 retinol binding protein 5, cellular -4.03606
SNX32 sorting nexin 32 -3.99246
DPP7 dipeptidyl-peptidase 7 -3.633
FLRT1 fibronectin leucine rich transmembrane protein 1 -3.52302
OMG oligodendrocyte myelin glycoprotein -3.47908
IPCEF1 interaction protein for cytohesin exchange factors 1 -3.2715
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6 -3.24045
PLAAT5 phospholipase A and acyltransferase 5 -3.06364
CASR calcium-sensing receptor -2.97689
ZNF160 zinc finger protein 160 -2.89316
EEF1AKMT2 EEF1A lysine methyltransferase 2 -2.84488
FBH1 F-box DNA helicase 1 -2.84488
STK11IP serine/threonine kinase 11 interacting protein -2.84488
HID1 HID1 domain containing -2.79713
ILF3 interleukin enhancer binding factor 3, 90kDa -2.79203
PSME3IP1 proteasome activator subunit 3 interacting protein 1 -2.68248
ZBTB21 zinc finger and BTB domain containing 21 -2.64583
MAGEF1 melanoma antigen family F1 -2.64583
CSRP2 cysteine and glycine-rich protein 2 -2.64583
BOP1 block of proliferation 1 -2.59127
MAPK10 mitogen-activated protein kinase 10 -2.56456
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) -2.55821
USP43 ubiquitin specific peptidase 43 -2.54956
AURKA aurora kinase A -2.47463
NAT14 N-acetyltransferase 14 (GCN5-related, putative) -2.47463
IZUMO2 IZUMO family member 2 -2.44774
R3HDM4 R3H domain containing 4 -2.42234
ACO1 aconitase 1, soluble -2.41847
NPIPB11 nuclear pore complex interacting protein family, member B11 -2.40924
TINCR tissue differentiation-inducing non-protein coding RNA -2.3957
RUMY3 RUMY family member 3 -2.3957
ZNF775 zinc finger protein 775 -2.3957
RHOBTB1 Rho-related BTB domain containing 1 -2.39043
KLHL10 kelch-like family member 10 -2.39043
RECK reversion-inducing-cysteine-rich protein with kazal motifs -2.388
BMI1 BMI1 proto-oncogene, polycomb ring finger -2.38318
HYAL3 hyaluronoglucosaminidase 3 -2.38318
RIMS4 regulating synaptic membrane exocytosis 4 -2.37077
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 -2.35851
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase -2.35851
ZBTB20 zinc finger and BTB domain containing 20 -2.35803
CAPN5 calpain 5 -2.32505
RAB6A RAB6A, member RAS oncogene family -2.32311
DNAH9 dynein, axonemal, heavy chain 9 -2.3053
PUS1 pseudouridylate synthase 1 -2.3053
CA11 carbonic anhydrase XI -2.29768
FRYL FRY-like -2.28424
COL5A1 collagen, type V, alpha 1 -2.26694
TRIM41 tripartite motif containing 41 -2.26251
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide -2.25714
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 -2.25714
SOCS6 suppressor of cytokine signaling 6 -2.25678
CDK3 cyclin-dependent kinase 3 -2.24898
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated) -2.2442
CATSPERD catsper channel auxiliary subunit delta -2.2442
CHRM2 cholinergic receptor, muscarinic 2 -2.23923
CLTRN collectrin, amino acid transport regulator -2.23923
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 -2.18199
BCLAF3 BCLAF1 and THRAP3 family member 3 -2.16717
IRF2BP2 interferon regulatory factor 2 binding protein 2 -2.15848
U2AF2 U2 small nuclear RNA auxiliary factor 2 -2.15294
MED27 mediator complex subunit 27 -2.14542
HPS4 Hermansky-Pudlak syndrome 4 -2.13869
STX3 syntaxin 3 -2.11149
TEX15 testis expressed 15 -2.10722
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 -2.10287
ERCC2 excision repair cross-complementation group 2 -2.09864
MCOLN1 mucolipin 1 -2.06565
NCKIPSD NCK interacting protein with SH3 domain -2.06287
CELF1 CUGBP, Elav-like family member 1 -2.06228
SPIN2B spindlin family, member 2B -2.04998
APCDD1 adenomatosis polyposis coli down-regulated 1 -2.04826
BSDC1 BSD domain containing 1 -2.0391
RBM48 RNA binding motif protein 48 -2.0391
EEFSEC eukaryotic elongation factor, selenocysteine-tRNA-specific -2.0242
UROS uroporphyrinogen III synthase -2.02393
TUBGCP3 tubulin, gamma complex associated protein 3 -2.01732
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 -2.01116
RABAC1 Rab acceptor 1 (prenylated) -2.01116
MINDY1 MINDY lysine 48 deubiquitinase 1 -2.00464
KCNV2 potassium channel, voltage gated modifier subfamily V, member 2 -2.00114
SYDE2 synapse defective 1, Rho GTPase, homolog 2 (C. elegans) -2.00096