MUSK Gene Set

Dataset Kinase Library Tyrosine Kinome Atlas
Category proteomics
Type kinase
Description muscle, skeletal, receptor tyrosine kinase|This gene encodes a muscle-specific tyrosine kinase receptor. The encoded protein may play a role in clustering of the acetylcholine receptor in the postsynaptic neuromuscular junction. Mutations in this gene have been associated with congenital myasthenic syndrome. Alternatively spliced transcript variants have been described.[provided by RefSeq, Oct 2009] (NCBI Entrez Gene Database, 4593)
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Genes

100 substrates of the kinase MUSK from the Kinase Library Tyrosine Kinome Atlas dataset.

Symbol Name Standardized Value
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa 100.0
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle) 99.96
THRB thyroid hormone receptor, beta 99.85
CKS2 CDC28 protein kinase regulatory subunit 2 99.63
MAPK7 mitogen-activated protein kinase 7 99.58
TRAF3IP2 TRAF3 interacting protein 2 99.39
PADI2 peptidyl arginine deiminase, type II 99.34
SHROOM1 shroom family member 1 99.28
TPRN taperin 99.26
TRIP11 thyroid hormone receptor interactor 11 99.25
LURAP1L leucine rich adaptor protein 1-like 99.23
RUSC2 RUN and SH3 domain containing 2 99.17
EGR1 early growth response 1 99.15
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 99.13
PRMT3 protein arginine methyltransferase 3 99.08
WWP2 WW domain containing E3 ubiquitin protein ligase 2 99.01
EML4 echinoderm microtubule associated protein like 4 98.97
MRPS27 mitochondrial ribosomal protein S27 98.95
ITSN1 intersectin 1 (SH3 domain protein) 98.9
MAPK1 mitogen-activated protein kinase 1 98.84
ANKZF1 ankyrin repeat and zinc finger domain containing 1 98.66
MOK MOK protein kinase 98.47
GOPC golgi-associated PDZ and coiled-coil motif containing 98.38
ADAM15 ADAM metallopeptidase domain 15 98.36
KLHDC3 kelch domain containing 3 98.32
KLC2 kinesin light chain 2 98.315
TERT telomerase reverse transcriptase 98.2
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila) 98.165
ZNF639 zinc finger protein 639 98.16
CHD2 chromodomain helicase DNA binding protein 2 98.05
MAPK15 mitogen-activated protein kinase 15 97.99
RPS29 ribosomal protein S29 97.99
RASGRP4 RAS guanyl releasing protein 4 97.92
CEP89 centrosomal protein 89kDa 97.9
CHAF1B chromatin assembly factor 1, subunit B (p60) 97.88
LYST lysosomal trafficking regulator 97.83
NOL10 nucleolar protein 10 97.79
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 97.74
STX16 syntaxin 16 97.72
CLDN4 claudin 4 97.68
NCOA7 nuclear receptor coactivator 7 97.66
TNN tenascin N 97.62
SLCO3A1 solute carrier organic anion transporter family, member 3A1 97.59
USP31 ubiquitin specific peptidase 31 97.5
CDKL5 cyclin-dependent kinase-like 5 97.31
RPS16 ribosomal protein S16 97.15
ZCCHC3 zinc finger, CCHC domain containing 3 97.05
HDAC6 histone deacetylase 6 97.0
UBASH3A ubiquitin associated and SH3 domain containing A 96.98
TIMMDC1 translocase of inner mitochondrial membrane domain containing 1 96.96
NDUFB10 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa 96.93
TRPV2 transient receptor potential cation channel, subfamily V, member 2 96.91
SMG8 SMG8 nonsense mediated mRNA decay factor 96.85
DDIAS DNA damage-induced apoptosis suppressor 96.8
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 96.74
CSNK2A2 casein kinase 2, alpha prime polypeptide 96.72
SIRT1 sirtuin 1 96.705
SEC14L1 SEC14-like 1 (S. cerevisiae) 96.7
GFPT1 glutamine--fructose-6-phosphate transaminase 1 96.69
RPL36AL ribosomal protein L36a-like 96.59
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 96.52
GIMAP4 GTPase, IMAP family member 4 96.35
HPSE heparanase 96.3
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial) 96.3
LHX3 LIM homeobox 3 96.28
LOC102725035 leukocyte immunoglobulin-like receptor subfamily B member 3 96.21
FPR2 formyl peptide receptor 2 96.13
SPANXN2 SPANX family, member N2 96.13
FKBP5 FK506 binding protein 5 96.11
VBP1 von Hippel-Lindau binding protein 1 96.08
MND1 meiotic nuclear divisions 1 homolog (S. cerevisiae) 96.02
EIF1B eukaryotic translation initiation factor 1B 95.97
EIF1 eukaryotic translation initiation factor 1 95.97
BYSL bystin-like 95.93
LMBR1 limb development membrane protein 1 95.88
MYO7B myosin VIIB 95.84
PRUNE2 prune homolog 2 (Drosophila) 95.82
GMPPA GDP-mannose pyrophosphorylase A 95.8
RGS10 regulator of G-protein signaling 10 95.71
IKZF3 IKAROS family zinc finger 3 (Aiolos) 95.62
TMEM185B transmembrane protein 185B 95.6
ZNF322 zinc finger protein 322 95.56
PRDX1 peroxiredoxin 1 95.54
PLPPR4 phospholipid phosphatase related 4 95.51
TRIM58 tripartite motif containing 58 95.5
BUB1 BUB1 mitotic checkpoint serine/threonine kinase 95.43
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B 95.42
CMKLR1 chemerin chemokine-like receptor 1 95.42
HINT1 histidine triad nucleotide binding protein 1 95.42
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 95.42
UBE2E2 ubiquitin-conjugating enzyme E2E 2 95.38
UBE2E3 ubiquitin-conjugating enzyme E2E 3 95.38
UBE2E1 ubiquitin-conjugating enzyme E2E 1 95.38
PCYOX1 prenylcysteine oxidase 1 95.3
CASQ2 calsequestrin 2 (cardiac muscle) 95.29
C1ORF210 chromosome 1 open reading frame 210 95.27
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 95.16
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2 95.08
PTPRA protein tyrosine phosphatase, receptor type, A 95.05
MYL11 myosin light chain 11 95.03