MX1 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description MX dynamin-like GTPase 1|This gene encodes a guanosine triphosphate (GTP)-metabolizing protein that participates in the cellular antiviral response. The encoded protein is induced by type I and type II interferons and antagonizes the replication process of several different RNA and DNA viruses. There is a related gene located adjacent to this gene on chromosome 21, and there are multiple pseudogenes located in a cluster on chromosome 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013] (NCBI Entrez Gene Database, 4599)
External Link https://ncbi.nlm.nih.gov/gene/4599
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Genes

497 genes differentially expressed following the MX1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.0170078
RPS4Y1 ribosomal protein S4, Y-linked 1 0.0156588
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 0.0120054
BGN biglycan 0.0115436
LTF lactotransferrin 0.0112975
ZBTB18 zinc finger and BTB domain containing 18 0.0103863
LCN2 lipocalin 2 0.0102683
DCXR dicarbonyl/L-xylulose reductase 0.010199
SIRT3 sirtuin 3 0.00990233
TXNDC9 thioredoxin domain containing 9 0.00988311
KDM5D lysine (K)-specific demethylase 5D 0.00973812
WIF1 WNT inhibitory factor 1 0.00945945
DHRS3 dehydrogenase/reductase (SDR family) member 3 0.00919202
MMP12 matrix metallopeptidase 12 0.00910788
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.00900618
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 0.00892391
ACSL5 acyl-CoA synthetase long-chain family member 5 0.0087439
CNN3 calponin 3, acidic 0.00862388
C4BPA complement component 4 binding protein, alpha 0.0085607
CEMIP cell migration inducing protein, hyaluronan binding 0.00853076
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 0.00844288
PCP4 Purkinje cell protein 4 0.00842345
S100A2 S100 calcium binding protein A2 0.00833857
MMP7 matrix metallopeptidase 7 0.00820413
NMU neuromedin U 0.00809448
LGALS13 lectin, galactoside-binding, soluble, 13 0.00799719
LRP4 low density lipoprotein receptor-related protein 4 0.00797943
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 0.00793481
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 0.00787791
APOC1 apolipoprotein C-I 0.00782013
SFTPD surfactant protein D 0.00774879
TSPAN7 tetraspanin 7 0.00770166
OIP5 Opa interacting protein 5 0.0076735
CALR calreticulin 0.00766726
ASF1A anti-silencing function 1A histone chaperone 0.00764989
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 0.00761658
ZDHHC6 zinc finger, DHHC-type containing 6 0.00759038
SFTPA2 surfactant protein A2 0.00757189
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha 0.00749833
BIRC5 baculoviral IAP repeat containing 5 0.00746426
CPB1 carboxypeptidase B1 (tissue) 0.00734431
CCNB2 cyclin B2 0.0072324
ORM1 orosomucoid 1 0.00721141
H2AFV H2A histone family, member V 0.00720031
PGD phosphogluconate dehydrogenase 0.00719415
CD9 CD9 molecule 0.00717688
PSAT1 phosphoserine aminotransferase 1 0.00715814
NRGN neurogranin (protein kinase C substrate, RC3) 0.00711982
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 0.00711713
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta 0.00711513
SORD sorbitol dehydrogenase 0.00708807
NPM3 nucleophosmin/nucleoplasmin 3 0.00704296
RHOB ras homolog family member B 0.00692085
ALOX5 arachidonate 5-lipoxygenase 0.00687567
ELN elastin 0.00686509
CXADR coxsackie virus and adenovirus receptor 0.00686171
FASN fatty acid synthase 0.00685175
C11ORF71 chromosome 11 open reading frame 71 0.00682145
OLFM1 olfactomedin 1 0.00677632
PID1 phosphotyrosine interaction domain containing 1 0.00676721
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 0.00675824
GLUL glutamate-ammonia ligase 0.00674759
NEIL3 nei endonuclease VIII-like 3 (E. coli) 0.00671547
H1-0 H1.0 linker histone 0.00669586
TSPAN8 tetraspanin 8 0.00668427
MET MET proto-oncogene, receptor tyrosine kinase 0.00661284
ESD esterase D 0.00660954
CD52 CD52 molecule 0.00660778
MYO5C myosin VC 0.0066072
PPP1R3C protein phosphatase 1, regulatory subunit 3C 0.00660665
RAD51AP1 RAD51 associated protein 1 0.0065951
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4 0.00655957
RNASEH2A ribonuclease H2, subunit A 0.00655121
ANOS1 anosmin 1 0.00654704
DCK deoxycytidine kinase 0.00652848
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 0.00651532
NR2F1 nuclear receptor subfamily 2, group F, member 1 0.00651295
SORBS2 sorbin and SH3 domain containing 2 0.00649416
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 0.0064824
VIPR1 vasoactive intestinal peptide receptor 1 0.00646804
CRYM crystallin, mu 0.00646163
ARID4A AT rich interactive domain 4A (RBP1-like) 0.00645056
DACH1 dachshund family transcription factor 1 0.00644436
DHCR24 24-dehydrocholesterol reductase 0.00643653
RFC2 replication factor C (activator 1) 2, 40kDa 0.00642765
MOXD1 monooxygenase, DBH-like 1 0.00639109
GCA grancalcin, EF-hand calcium binding protein 0.00634521
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 0.00634192
RNF43 ring finger protein 43 0.00630745
SDHAF3 succinate dehydrogenase complex assembly factor 3 0.00630614
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4 0.00629205
MALL mal, T-cell differentiation protein-like 0.00628146
MRPL20 mitochondrial ribosomal protein L20 0.00627146
PAN2 PAN2 poly(A) specific ribonuclease subunit 0.00621081
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.00620903
RGS10 regulator of G-protein signaling 10 0.00618223
MERTK MER proto-oncogene, tyrosine kinase 0.00617903
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 0.00617833
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 0.00615849
C1ORF115 chromosome 1 open reading frame 115 0.00615823
BMP4 bone morphogenetic protein 4 0.00614376
DMBT1 deleted in malignant brain tumors 1 0.0061308
OLFM4 olfactomedin 4 0.00612051
SPC25 SPC25, NDC80 kinetochore complex component 0.00611937
ACTL6A actin-like 6A 0.00611801
CBR4 carbonyl reductase 4 0.00609987
KIF20A kinesin family member 20A 0.00606707
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.00606195
ANKRD49 ankyrin repeat domain 49 0.00606171
CIT citron rho-interacting serine/threonine kinase 0.00605147
TCTA T-cell leukemia translocation altered 0.0060513
CD1C CD1c molecule 0.00605076
PSPH phosphoserine phosphatase 0.00603736
ADSL adenylosuccinate lyase 0.00603467
EXPH5 exophilin 5 0.00603156
CHKB choline kinase beta 0.00600847
ATP10B ATPase, class V, type 10B 0.00598142
TARDBP TAR DNA binding protein 0.00597828
CCNA2 cyclin A2 0.00594403
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 0.00590946
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.00590627
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.00584311
APIP APAF1 interacting protein 0.00584135
DOCK4 dedicator of cytokinesis 4 0.00583783
IL1R1 interleukin 1 receptor, type I 0.00583278
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 0.00581455
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3 0.00580929
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 0.00578051
FADS1 fatty acid desaturase 1 0.00576614
MEX3D mex-3 RNA binding family member D 0.00575689
GPD1L glycerol-3-phosphate dehydrogenase 1-like 0.00575265
CD2 CD2 molecule 0.00573916
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit 0.0057337
FGFR3 fibroblast growth factor receptor 3 0.00573112
FBLN1 fibulin 1 0.0057305
GCAT glycine C-acetyltransferase 0.00572195
CEP68 centrosomal protein 68kDa 0.00570746
TMEM38B transmembrane protein 38B 0.00570401
INSIG1 insulin induced gene 1 0.00570372
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.00569642
DPYSL3 dihydropyrimidinase-like 3 0.00568743
SMCO4 single-pass membrane protein with coiled-coil domains 4 0.00567229
LYZ lysozyme 0.0056669
ELOVL6 ELOVL fatty acid elongase 6 0.00566543
PARK7 parkinson protein 7 0.00566148
NT5DC2 5'-nucleotidase domain containing 2 0.00564984
AURKB aurora kinase B 0.00558072
TMC5 transmembrane channel-like 5 0.00557424
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 0.00556697
ACACA acetyl-CoA carboxylase alpha 0.00556331
DESI1 desumoylating isopeptidase 1 0.00555902
GNG4 guanine nucleotide binding protein (G protein), gamma 4 0.00552721
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 0.0055189
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.00549054
SRGN serglycin 0.00548972
VBP1 von Hippel-Lindau binding protein 1 0.00542973
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 0.00542817
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor 0.00541981
FRZB frizzled-related protein 0.00541969
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.00541767
CD320 CD320 molecule 0.00541159
ABHD2 abhydrolase domain containing 2 0.00541102
LTB lymphotoxin beta (TNF superfamily, member 3) 0.00540513
SET SET nuclear proto-oncogene 0.00540423
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 0.00539481
COL1A2 collagen, type I, alpha 2 0.0053918
CTNND1 catenin (cadherin-associated protein), delta 1 0.00538162
SLCO1B3 solute carrier organic anion transporter family, member 1B3 0.0053716
KIF18B kinesin family member 18B 0.00537004
CDK1 cyclin-dependent kinase 1 0.0053652
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 0.00536253
MREG melanoregulin 0.00535357
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 0.00532972
SMIM8 small integral membrane protein 8 0.005316
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.00531361
RAPSN receptor-associated protein of the synapse 0.00529746
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 0.00529196
RPA3 replication protein A3, 14kDa 0.00528831
KDM1A lysine (K)-specific demethylase 1A 0.00528625
AIMP1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 0.00528388
MPO myeloperoxidase 0.00528026
TMSB15A thymosin beta 15a 0.00527479
ASNSD1 asparagine synthetase domain containing 1 0.00526228
EPHB2 EPH receptor B2 0.00523417
FABP1 fatty acid binding protein 1, liver 0.00522893
NSMCE4A non-SMC element 4 homolog A (S. cerevisiae) 0.00522881
NSL1 NSL1, MIS12 kinetochore complex component 0.00522507
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator 0.00521316
CDC7 cell division cycle 7 0.00520173
ITGA6 integrin, alpha 6 0.00519978
PIMREG PICALM interacting mitotic regulator 0.0051984
LIMCH1 LIM and calponin homology domains 1 0.005179
SERBP1 SERPINE1 mRNA binding protein 1 0.00516565
FERMT1 fermitin family member 1 0.00515679
CDC6 cell division cycle 6 0.00515622
RASSF7 Ras association (RalGDS/AF-6) domain family (N-terminal) member 7 0.00515561
C9ORF16 chromosome 9 open reading frame 16 0.00515186
GSTO1 glutathione S-transferase omega 1 0.00514756
FBXW2 F-box and WD repeat domain containing 2 0.0051471
NCAPH non-SMC condensin I complex, subunit H 0.00514696
MIOS missing oocyte, meiosis regulator, homolog (Drosophila) 0.00513766
RBX1 ring-box 1, E3 ubiquitin protein ligase 0.00513691
LBR lamin B receptor 0.00513381
SLC17A9 solute carrier family 17 (vesicular nucleotide transporter), member 9 0.00511866
PGAP2 post-GPI attachment to proteins 2 0.0051161
C8ORF4 chromosome 8 open reading frame 4 0.00510543
MXRA7 matrix-remodelling associated 7 0.0050957
EAPP E2F-associated phosphoprotein 0.00509564
CYB5B cytochrome b5 type B (outer mitochondrial membrane) 0.00507465
PGC progastricsin (pepsinogen C) 0.00507412
CD48 CD48 molecule 0.00505848
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 0.00504322
RMI1 RecQ mediated genome instability 1 0.00503859
DENND2B DENN domain containing 2B 0.00503652
IRF6 interferon regulatory factor 6 0.00503261
DUOX2 dual oxidase 2 0.00501928
POMZP3 POM121 and ZP3 fusion 0.00500706
ANGEL2 angel homolog 2 (Drosophila) 0.00499897
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) 0.00499877
ALPK3 alpha-kinase 3 0.00499676
TGM2 transglutaminase 2 0.00499033
BRCA1 breast cancer 1, early onset 0.00498878
MUC4 mucin 4, cell surface associated 0.00496102
GPX2 glutathione peroxidase 2 0.00494708
NCAPD3 non-SMC condensin II complex, subunit D3 0.00494449
LPPR1 lipid phosphate phosphatase-related protein type 1 0.0049404
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit 0.00493971
ABHD10 abhydrolase domain containing 10 0.00493926
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 0.0049376
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme 0.0049367
CAAP1 caspase activity and apoptosis inhibitor 1 0.00492869
SIM2 single-minded family bHLH transcription factor 2 0.00492124
LTA4H leukotriene A4 hydrolase 0.00491658
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 0.00490814
PDE9A phosphodiesterase 9A 0.00490678
HPX hemopexin 0.00490362
IGFBP1 insulin-like growth factor binding protein 1 0.0049009
PRIM1 primase, DNA, polypeptide 1 (49kDa) 0.00489774
AHSG alpha-2-HS-glycoprotein 0.00489734
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 0.00489431
SFTPB surfactant protein B 0.0048911
PRMT3 protein arginine methyltransferase 3 0.00488072
PRKD3 protein kinase D3 0.00486673
RRAS2 related RAS viral (r-ras) oncogene homolog 2 0.0048661
CCRL2 chemokine (C-C motif) receptor-like 2 0.00485161
CDT1 chromatin licensing and DNA replication factor 1 0.00484927
RPL36 ribosomal protein L36 0.00484217
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 0.00484064
PRMT1 protein arginine methyltransferase 1 0.0048383

decreased expression

Symbol Name Standardized Value
SSBP2 single-stranded DNA binding protein 2 -0.0229313
IFI27 interferon, alpha-inducible protein 27 -0.015995
COG7 component of oligomeric golgi complex 7 -0.0137679
PROM1 prominin 1 -0.0131418
SFRP1 secreted frizzled-related protein 1 -0.0122628
NPIPB3 nuclear pore complex interacting protein family, member B3 -0.0117978
MAP7 microtubule-associated protein 7 -0.0116259
PLAAT3 phospholipase A and acyltransferase 3 -0.0111171
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 -0.0106686
CLTB clathrin, light chain B -0.0106451
TENT5A terminal nucleotidyltransferase 5A -0.0106297
VCL vinculin -0.0101488
AZGP1 alpha-2-glycoprotein 1, zinc-binding -0.0100008
ADAT1 adenosine deaminase, tRNA-specific 1 -0.00992279
TFPI2 tissue factor pathway inhibitor 2 -0.00991919
TGFBR3 transforming growth factor, beta receptor III -0.00977847
MAGEA3 melanoma antigen family A3 -0.00976803
HMOX1 heme oxygenase 1 -0.00970896
MX1 MX dynamin-like GTPase 1 -0.00964873
MFAP5 microfibrillar associated protein 5 -0.00963058
KRT14 keratin 14, type I -0.00961524
HSPA1A heat shock 70kDa protein 1A -0.0095665
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 -0.00952086
IL1B interleukin 1, beta -0.00951735
KRT23 keratin 23, type I -0.00950096
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 -0.00946645
KLF4 Kruppel-like factor 4 (gut) -0.00924816
PHLDA2 pleckstrin homology-like domain, family A, member 2 -0.00917639
CRYAB crystallin, alpha B -0.00911624
CTSA cathepsin A -0.00910544
IER5 immediate early response 5 -0.00908017
ITM2A integral membrane protein 2A -0.0090533
IFI6 interferon, alpha-inducible protein 6 -0.00904745
INAVA innate immunity activator -0.00904732
COL15A1 collagen, type XV, alpha 1 -0.00901478
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D -0.0090085
XIC X chromosome inactivation center -0.00900264
VLDLR very low density lipoprotein receptor -0.00894265
KLK5 kallikrein-related peptidase 5 -0.00893139
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog -0.0089298
AMIGO2 adhesion molecule with Ig-like domain 2 -0.00891134
SPRED2 sprouty-related, EVH1 domain containing 2 -0.00888444
MATN2 matrilin 2 -0.00886821
MIR22HG MIR22 host gene -0.00885761
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b -0.00884411
SNAI2 snail family zinc finger 2 -0.00878451
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 -0.00868734
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 -0.00867702
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) -0.00866767
OXTR oxytocin receptor -0.00866687
SCGB2A2 secretoglobin, family 2A, member 2 -0.008666
TFF1 trefoil factor 1 -0.00864033
EPB41L3 erythrocyte membrane protein band 4.1-like 3 -0.00855746
CXCL10 chemokine (C-X-C motif) ligand 10 -0.00853695
MYOF myoferlin -0.00848731
DUSP5 dual specificity phosphatase 5 -0.00837647
G0S2 G0/G1 switch 2 -0.00836968
CTSK cathepsin K -0.00827362
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -0.00820553
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) -0.00820045
TMEM45A transmembrane protein 45A -0.00819271
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1) -0.00816991
NPY1R neuropeptide Y receptor Y1 -0.00814848
ELF4 E74-like factor 4 (ets domain transcription factor) -0.00810034
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.00808523
GOLGA8H golgin A8 family, member H -0.0080059
HSPA2 heat shock 70kDa protein 2 -0.00799388
RGS16 regulator of G-protein signaling 16 -0.00798909
PUF60 poly-U binding splicing factor 60KDa -0.00798419
CRABP2 cellular retinoic acid binding protein 2 -0.00795776
PNMA8A PNMA family member 8A -0.00793843
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -0.00791301
CX3CR1 chemokine (C-X3-C motif) receptor 1 -0.00791299
MVP major vault protein -0.00788445
TUFT1 tuftelin 1 -0.00784445
HIST1H2BD histone cluster 1, H2bd -0.00766041
FLRT3 fibronectin leucine rich transmembrane protein 3 -0.00764344
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) -0.00757019
RET ret proto-oncogene -0.00755887
PERP PERP, TP53 apoptosis effector -0.00755068
CA2 carbonic anhydrase II -0.00754707
PEG10 paternally expressed 10 -0.00752561
NRCAM neuronal cell adhesion molecule -0.00752313
KLF5 Kruppel-like factor 5 (intestinal) -0.00751501
TPBG trophoblast glycoprotein -0.00749978
COL9A3 collagen, type IX, alpha 3 -0.00747697
FHL2 four and a half LIM domains 2 -0.00744609
CALML5 calmodulin-like 5 -0.00737217
TAC1 tachykinin, precursor 1 -0.00736118
KLF6 Kruppel-like factor 6 -0.00735279
ENPEP glutamyl aminopeptidase (aminopeptidase A) -0.00734996
NOTCH2NL notch 2 N-terminal like -0.00734915
STK26 serine/threonine protein kinase 26 -0.00733006
PTGER4 prostaglandin E receptor 4 (subtype EP4) -0.00725245
MAGED2 melanoma antigen family D2 -0.00722233
PLAGL1 pleiomorphic adenoma gene-like 1 -0.00721515
PRSS23 protease, serine, 23 -0.00721161
GADD45A growth arrest and DNA-damage-inducible, alpha -0.00721043
COL4A5 collagen, type IV, alpha 5 -0.00713474
NAP1L2 nucleosome assembly protein 1-like 2 -0.00711517
IL6R interleukin 6 receptor -0.0070889
APOD apolipoprotein D -0.00706867
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 -0.00702884
ECM1 extracellular matrix protein 1 -0.00701394
OSR2 odd-skipped related transciption factor 2 -0.00699731
DUSP4 dual specificity phosphatase 4 -0.00698833
SLC39A6 solute carrier family 39 (zinc transporter), member 6 -0.00698388
RRAGC Ras-related GTP binding C -0.00698052
PGAM1 phosphoglycerate mutase 1 (brain) -0.00697806
AREG amphiregulin -0.00696305
MYC v-myc avian myelocytomatosis viral oncogene homolog -0.00693496
OPN3 opsin 3 -0.00692902
SCGB2A1 secretoglobin, family 2A, member 1 -0.00690629
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 -0.00682485
DSP desmoplakin -0.00681897
OSBPL1A oxysterol binding protein-like 1A -0.00681743
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase -0.00681498
EFNB2 ephrin-B2 -0.00681265
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) -0.00678133
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 -0.00676697
RIPK2 receptor-interacting serine-threonine kinase 2 -0.0067545
MGLL monoglyceride lipase -0.00674948
ASS1 argininosuccinate synthase 1 -0.00674515
BTK Bruton agammaglobulinemia tyrosine kinase -0.0067442
FAM46C family with sequence similarity 46, member C -0.00674391
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 -0.00671696
DUSP6 dual specificity phosphatase 6 -0.00671219
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 -0.00667414
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) -0.00666143
NT5E 5'-nucleotidase, ecto (CD73) -0.00665093
RNF24 ring finger protein 24 -0.00662535
HSPB8 heat shock 22kDa protein 8 -0.00661885
AKAP8 A kinase (PRKA) anchor protein 8 -0.00661533
HIST1H2BK histone cluster 1, H2bk -0.0065789
WT1 Wilms tumor 1 -0.00655391
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) -0.00652088
PRL prolactin -0.00649488
F13A1 coagulation factor XIII, A1 polypeptide -0.00649224
MAST4 microtubule associated serine/threonine kinase family member 4 -0.00648851
NID2 nidogen 2 (osteonidogen) -0.00647521
SPRY4 sprouty homolog 4 (Drosophila) -0.00646809
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A -0.00644863
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5 -0.00644647
RECK reversion-inducing-cysteine-rich protein with kazal motifs -0.00642308
HSPA6 heat shock 70kDa protein 6 (HSP70B') -0.00636856
ANK2 ankyrin 2, neuronal -0.00636209
SLC22A18 solute carrier family 22, member 18 -0.00635154
BCL3 B-cell CLL/lymphoma 3 -0.00634968
RNF125 ring finger protein 125, E3 ubiquitin protein ligase -0.00634879
RBPMS RNA binding protein with multiple splicing -0.00633907
ADCY9 adenylate cyclase 9 -0.0063388
RASA4 RAS p21 protein activator 4 -0.00633016
ADAM10 ADAM metallopeptidase domain 10 -0.00632929
ISG15 ISG15 ubiquitin-like modifier -0.00632756
PLK2 polo-like kinase 2 -0.00628663
MAGEA12 melanoma antigen family A12 -0.00628032
PBX3 pre-B-cell leukemia homeobox 3 -0.00626749
MITF microphthalmia-associated transcription factor -0.00626191
SCPEP1 serine carboxypeptidase 1 -0.00624197
PXDN peroxidasin -0.00622337
PDPK1 3-phosphoinositide dependent protein kinase 1 -0.00619974
MAP1LC3B microtubule-associated protein 1 light chain 3 beta -0.00619806
SAMD4A sterile alpha motif domain containing 4A -0.00619236
IRF7 interferon regulatory factor 7 -0.00618364
NEFH neurofilament, heavy polypeptide -0.00616787
ANO1 anoctamin 1, calcium activated chloride channel -0.00616326
TFF2 trefoil factor 2 -0.00616206
MX2 MX dynamin-like GTPase 2 -0.0061609
REEP1 receptor accessory protein 1 -0.00614817
MEG3 maternally expressed 3 (non-protein coding) -0.00613761
PDGFD platelet derived growth factor D -0.00613737
FAM102A family with sequence similarity 102, member A -0.00611491
ANKRD11 ankyrin repeat domain 11 -0.00610072
TDRD7 tudor domain containing 7 -0.00608126
FRY furry homolog (Drosophila) -0.00606278
ZMAT3 zinc finger, matrin-type 3 -0.00605632
LIMK2 LIM domain kinase 2 -0.00604079
ZNF91 zinc finger protein 91 -0.00602573
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 -0.00601707
SSPN sarcospan -0.00601127
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 -0.00600535
MARCH3 membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase -0.00599697
SYNGR3 synaptogyrin 3 -0.00599492
ZEB2 zinc finger E-box binding homeobox 2 -0.00599431
PLCE1 phospholipase C, epsilon 1 -0.00598805
OGN osteoglycin -0.00598334
CFH complement factor H -0.00597092
GPR183 G protein-coupled receptor 183 -0.00595301
ANK3 ankyrin 3, node of Ranvier (ankyrin G) -0.00592646
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 -0.00592569
GAS1 growth arrest-specific 1 -0.00592063
TM9SF3 transmembrane 9 superfamily member 3 -0.00591707
SMAD3 SMAD family member 3 -0.00591063
CHD4 chromodomain helicase DNA binding protein 4 -0.00590702
MBL2 mannose-binding lectin (protein C) 2, soluble -0.0059053
TRIM44 tripartite motif containing 44 -0.00590309
FMO1 flavin containing monooxygenase 1 -0.00590137
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.00588888
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 -0.00587962
GULP1 GULP, engulfment adaptor PTB domain containing 1 -0.00587931
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 -0.00586998
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1 -0.00586744
QPRT quinolinate phosphoribosyltransferase -0.00585874
DCN decorin -0.00585297
FBN2 fibrillin 2 -0.00580633
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.00580051
GAS6 growth arrest-specific 6 -0.00579399
PDGFRL platelet-derived growth factor receptor-like -0.00578665
IGFBP6 insulin-like growth factor binding protein 6 -0.00578017
COL6A2 collagen, type VI, alpha 2 -0.00577882
AHNAK2 AHNAK nucleoprotein 2 -0.00576738
TRPS1 trichorhinophalangeal syndrome I -0.00575543
S100A14 S100 calcium binding protein A14 -0.00574847
CCN3 cellular communication network factor 3 -0.00573654
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 -0.0057358
KLC1 kinesin light chain 1 -0.00573333
WDR7 WD repeat domain 7 -0.00573267
GALC galactosylceramidase -0.00572702
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12 -0.00572554
IGF2R insulin-like growth factor 2 receptor -0.00571082
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 -0.00570735
TMEM255A transmembrane protein 255A -0.00570426
CDC20 cell division cycle 20 -0.005686
SRPX sushi-repeat containing protein, X-linked -0.00567951
KRT8 keratin 8, type II -0.00567217
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta -0.00566243
TAOK3 TAO kinase 3 -0.00565636
TLE4 transducin-like enhancer of split 4 -0.00565062
IDS iduronate 2-sulfatase -0.00564751
BEX4 brain expressed, X-linked 4 -0.00564537
DHTKD1 dehydrogenase E1 and transketolase domain containing 1 -0.00560027
OLFML2A olfactomedin-like 2A -0.00559389
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 -0.00558942
CSAD cysteine sulfinic acid decarboxylase -0.00558328
KRT7 keratin 7, type II -0.00557533
GPR137B G protein-coupled receptor 137B -0.00556379
CCL8 chemokine (C-C motif) ligand 8 -0.00554256
CLIC4 chloride intracellular channel 4 -0.00552672
COL11A1 collagen, type XI, alpha 1 -0.00552193
GABARAPL1 GABA(A) receptor-associated protein like 1 -0.00552036
MFGE8 milk fat globule-EGF factor 8 protein -0.00551397
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 -0.00551334
S100A11 S100 calcium binding protein A11 -0.00550168
STC1 stanniocalcin 1 -0.00549561
TRIB1 tribbles pseudokinase 1 -0.00548512
RBMS1 RNA binding motif, single stranded interacting protein 1 -0.00547989
ZNF160 zinc finger protein 160 -0.00545493
PHIP pleckstrin homology domain interacting protein -0.00544107