MYB Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description v-myb avian myeloblastosis viral oncogene homolog|This gene encodes a transcription factor that is a member of the MYB family of transcription factor genes. The protein contains three domains, an N-terminal DNA-binding domain, a central transcriptional activation domain and a C-terminal domain involved in transcriptional repression. This protein plays an essential role in the regulation of hematopoiesis and may play a role in tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2009] (NCBI Entrez Gene Database, 4602)
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Genes

324 genes differentially expressed following the MYB gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
SLFN12L schlafen family member 12-like 3.45097
DLX3 distal-less homeobox 3 3.45097
PLAAT4 phospholipase A and acyltransferase 4 3.45097
CLIP4 CAP-GLY domain containing linker protein family, member 4 3.45097
SEMG1 semenogelin I 3.45097
DNASE1L2 deoxyribonuclease I-like 2 3.45097
NANOS2 nanos homolog 2 (Drosophila) 3.45097
CLPSL1 colipase-like 1 3.45097
S100G S100 calcium binding protein G 3.45097
TRAF3IP3 TRAF3 interacting protein 3 3.45097
LRRN4CL LRRN4 C-terminal like 3.45097
LTB lymphotoxin beta (TNF superfamily, member 3) 3.45097
SLC39A4 solute carrier family 39 (zinc transporter), member 4 3.45097
PLCD4 phospholipase C, delta 4 3.45097
CLEC19A C-type lectin domain family 19, member A 3.45097
BHLHA15 basic helix-loop-helix family, member a15 3.45097
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 3.45097
SPDYE11 speedy/RINGO cell cycle regulator family member E11 3.45097
DLX4 distal-less homeobox 4 3.45097
LCN10 lipocalin 10 3.45097
CXORF58 chromosome X open reading frame 58 3.45097
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 3.45097
GPR146 G protein-coupled receptor 146 3.45097
SOX18 SRY (sex determining region Y)-box 18 3.42898
PLIN4 perilipin 4 3.42898
UGT1A5 UDP glucuronosyltransferase 1 family, polypeptide A5 3.42898
HMGCLL1 3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1 3.42898
DUXB double homeobox B 3.42898
MILR1 mast cell immunoglobulin-like receptor 1 3.42898
TMEM244 transmembrane protein 244 3.42898
PRSS41 protease, serine, 41 3.42898
TXNDC8 thioredoxin domain containing 8 (spermatozoa) 3.42898
CDH5 cadherin 5, type 2 (vascular endothelium) 3.42898
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy 3.42898
ALOX15 arachidonate 15-lipoxygenase 3.42898
OR10A6 olfactory receptor, family 10, subfamily A, member 6 (gene/pseudogene) 3.42898
GUCY2D guanylate cyclase 2D, membrane (retina-specific) 3.42898
TRPV5 transient receptor potential cation channel, subfamily V, member 5 3.42898
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic 3.42898
SLC9C2 solute carrier family 9, member C2 (putative) 3.42898
SLC23A3 solute carrier family 23, member 3 3.42898
GPR26 G protein-coupled receptor 26 3.42898
NUGGC nuclear GTPase, germinal center associated 3.42898
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 3.42898
OPRL1 opiate receptor-like 1 3.42898
SLC30A4 solute carrier family 30 (zinc transporter), member 4 3.42898
ASB12 ankyrin repeat and SOCS box containing 12 3.42898
DMRTC1B DMRT-like family C1B 3.42898
APOA2 apolipoprotein A-II 3.42898
SLC16A6 solute carrier family 16, member 6 3.42898
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 3.42898
SKOR2 SKI family transcriptional corepressor 2 3.42898
SLC25A45 solute carrier family 25, member 45 3.42898
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18 3.42898
TMPRSS11A transmembrane protease, serine 11A 3.42898
PLPP4 phospholipid phosphatase 4 3.42898
PCDHGA9 protocadherin gamma subfamily A, 9 3.42898
GPX5 glutathione peroxidase 5 3.42898
VN1R1 vomeronasal 1 receptor 1 3.42898
RD3 retinal degeneration 3 3.42898
FMO1 flavin containing monooxygenase 1 3.42898
FMOD fibromodulin 3.42898
MYEOV myeloma overexpressed 3.42898
SPATA46 spermatogenesis associated 46 3.42898
MEIOSIN meiosis initiator 3.42898
SPEGNB SPEG neighbor 3.42898
ANKRD42-DT ANKRD42 divergent transcript 3.42898
TMDD1 transmembrane and death domain 1 3.42898
CIMAP1B ciliary microtubule associated protein 1B 3.42898
RHEX regulator of hemoglobinization and erythroid cell expansion 3.42898
PEAK3 PEAK family member 3 3.42898
CFAP276 cilia and flagella associated protein 276 3.42898
CCDC197 coiled-coil domain containing 197 3.42898
GCSAM germinal center-associated, signaling and motility 3.42898
GATA1 GATA binding protein 1 (globin transcription factor 1) 3.42898
MEOX1 mesenchyme homeobox 1 3.42898
PRB4 proline-rich protein BstNI subfamily 4 3.42898
SLC35D3 solute carrier family 35, member D3 3.42898
ACOT1 acyl-CoA thioesterase 1 3.42898
CD300LG CD300 molecule-like family member g 3.42898
TMEM229B transmembrane protein 229B 3.42898
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 3.42898
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6 3.42898
CCDC92 coiled-coil domain containing 92 3.42898
TLR5 toll-like receptor 5 3.42898
CSAG2 CSAG family, member 2 3.42898
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) 3.42898
ASZ1 ankyrin repeat, SAM and basic leucine zipper domain containing 1 3.42898
PXDC1 PX domain containing 1 3.42898
PMP22 peripheral myelin protein 22 3.42898
CDKN2A cyclin-dependent kinase inhibitor 2A 3.42898
CFAP45 cilia and flagella associated protein 45 3.42898
GZMM granzyme M (lymphocyte met-ase 1) 3.42898
SPMIP10 sperm microtubule inner protein 10 3.42898
SLC13A2 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 3.42898
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 3.42898
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 3.42898
STMND1 stathmin domain containing 1 3.42898
ITGB7 integrin, beta 7 3.42898
SP100 SP100 nuclear antigen 3.42898
PAGE2B P antigen family, member 2B 3.42898
TF transferrin 3.42898
FITM1 fat storage-inducing transmembrane protein 1 3.42898
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) 3.42898
CHRM4 cholinergic receptor, muscarinic 4 3.42898
HHIPL2 HHIP-like 2 3.42898
AQP1 aquaporin 1 (Colton blood group) 3.42898
ANKRD55 ankyrin repeat domain 55 3.42898
SLC51B solute carrier family 51, beta subunit 3.42898
STRC stereocilin 3.42898
MAPK11 mitogen-activated protein kinase 11 3.42898
PCDHGA3 protocadherin gamma subfamily A, 3 3.42898
AMIGO1 adhesion molecule with Ig-like domain 1 3.42898
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 3.42898
CPSF4L cleavage and polyadenylation specific factor 4-like 3.42898
SLC32A1 solute carrier family 32 (GABA vesicular transporter), member 1 3.42898
ADAM2 ADAM metallopeptidase domain 2 3.42898
MBOAT4 membrane bound O-acyltransferase domain containing 4 3.42898
ALAS2 5'-aminolevulinate synthase 2 3.42898
PHOSPHO1 phosphatase, orphan 1 3.42898
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 3.42898
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 3.42898
ESAM endothelial cell adhesion molecule 3.42898
DRD2 dopamine receptor D2 3.42898
PRSS55 protease, serine, 55 3.42898
ART1 ADP-ribosyltransferase 1 3.42898
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle) 3.42898
CLCNKA chloride channel, voltage-sensitive Ka 3.42898
ANKRD53 ankyrin repeat domain 53 3.42898
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 3.42898
DMRT1 doublesex and mab-3 related transcription factor 1 3.42898
CCDC87 coiled-coil domain containing 87 3.42898
TLDC2 TBC/LysM-associated domain containing 2 3.42898
SPACA5 sperm acrosome associated 5 3.42898
HMX3 H6 family homeobox 3 3.42898
AIRE autoimmune regulator 3.42898
DEFB135 defensin, beta 135 3.42898
CAPSL calcyphosine-like 3.42898
MEPE matrix extracellular phosphoglycoprotein 3.42898
KRT77 keratin 77, type II 3.42898
SFTA2 surfactant associated 2 3.42898
RPL12 ribosomal protein L12 3.42898
FOXJ1 forkhead box J1 3.42898
OR5A1 olfactory receptor, family 5, subfamily A, member 1 3.42898
PRSS22 protease, serine, 22 3.42898
FCAR Fc fragment of IgA receptor 3.42898
TEX35 testis expressed 35 3.42898
MMP19 matrix metallopeptidase 19 3.42898
DNAH1 dynein, axonemal, heavy chain 1 3.42898
CLNK cytokine-dependent hematopoietic cell linker 3.42898
TMEM88 transmembrane protein 88 3.42898
IL17B interleukin 17B 3.42898
OR14A2 olfactory receptor, family 14, subfamily A, member 2 3.42898
OTUD6A OTU deubiquitinase 6A 3.42898
PRTN3 proteinase 3 3.42898
DCST2 DC-STAMP domain containing 2 3.42898
HIGD2B HIG1 hypoxia inducible domain family, member 2B 3.42898
FXYD3 FXYD domain containing ion transport regulator 3 3.42898
JOSD2 Josephin domain containing 2 3.41047
IGSF10 immunoglobulin superfamily, member 10 3.41047
CRIP3 cysteine-rich protein 3 3.24511
TP63 tumor protein p63 2.99273
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled 2.94213
NIFK nucleolar protein interacting with the FHA domain of MKI67 2.89623
PIM2 Pim-2 proto-oncogene, serine/threonine kinase 2.86334
POP7 processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae) 2.8568
FIGN fidgetin 2.85057
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 2.82077
C3ORF70 chromosome 3 open reading frame 70 2.79979
PTPN21 protein tyrosine phosphatase, non-receptor type 21 2.75439
CTCF CCCTC-binding factor (zinc finger protein) 2.75239
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 2.61342
PHKB phosphorylase kinase, beta 2.55838
SLC35B2 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2 2.55111
ATP5ME ATP synthase membrane subunit e 2.54925
PPP1R1C protein phosphatase 1, regulatory (inhibitor) subunit 1C 2.49375
FAM43B family with sequence similarity 43, member B 2.47499
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 2.47499
TMEM82 transmembrane protein 82 2.47499
ALX3 ALX homeobox 3 2.42959
TDRD7 tudor domain containing 7 2.42959
FLT3LG fms-related tyrosine kinase 3 ligand 2.42959
CFAP74 cilia and flagella associated protein 74 2.42959
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1 2.41748
TMEM269 transmembrane protein 269 2.40378
KLK5 kallikrein-related peptidase 5 2.39901
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) 2.36379
FUOM fucose mutarotase 2.35562
MS4A15 membrane-spanning 4-domains, subfamily A, member 15 2.35374
ECSIT ECSIT signalling integrator 2.24129
TAGLN2 transgelin 2 2.21912
RNF103 ring finger protein 103 2.21557
EVA1C eva-1 homolog C (C. elegans) 2.21133
SPTBN2 spectrin, beta, non-erythrocytic 2 2.20362
DUSP19 dual specificity phosphatase 19 2.16324
RPL27A ribosomal protein L27a 2.15728
TUBB6 tubulin, beta 6 class V 2.14927
RAB3IL1 RAB3A interacting protein (rabin3)-like 1 2.1254
RBM19 RNA binding motif protein 19 2.12269
ZNF385D zinc finger protein 385D 2.09547
ADGRB2 adhesion G protein-coupled receptor B2 2.08801
VPS50 VPS50 subunit of EARP/GARPII complex 2.0864
LRRC8C leucine rich repeat containing 8 family, member C 2.06257
TOB1 transducer of ERBB2, 1 2.01337
SYT6 synaptotagmin VI 2.01337
TMEM245 transmembrane protein 245 2.01159
MPND MPN domain containing 2.01159
MTPN myotrophin 2.00995

decreased expression

Symbol Name Standardized Value
EBF4 early B-cell factor 4 -3.42898
PTAFR platelet-activating factor receptor -3.42898
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa -3.42898
RPH3AL rabphilin 3A-like (without C2 domains) -3.42898
MAN1A2 mannosidase, alpha, class 1A, member 2 -3.42898
TSGA10IP testis specific, 10 interacting protein -3.42898
TSHR thyroid stimulating hormone receptor -3.42898
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7 -3.42898
SLC5A8 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8 -3.41047
OSTN osteocrin -3.41047
FRAT1 frequently rearranged in advanced T-cell lymphomas 1 -3.41047
PCDHB10 protocadherin beta 10 -3.41047
HTR3E 5-hydroxytryptamine (serotonin) receptor 3E, ionotropic -3.41047
SLC22A16 solute carrier family 22 (organic cation/carnitine transporter), member 16 -3.41047
CNGA4 cyclic nucleotide gated channel alpha 4 -3.41047
VWC2L von Willebrand factor C domain containing protein 2-like -3.41047
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) -3.41047
AGBL1 ATP/GTP binding protein-like 1 -3.41047
FPR3 formyl peptide receptor 3 -3.41047
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta -3.41047
NUTM2G NUT family member 2G -3.41047
ABCA13 ATP-binding cassette, sub-family A (ABC1), member 13 -3.41047
HAL histidine ammonia-lyase -3.41047
ASIC4 acid sensing (proton gated) ion channel family member 4 -3.41047
RGS11 regulator of G-protein signaling 11 -3.41047
SPDYE17 speedy/RINGO cell cycle regulator family member E17 -3.41047
CATSPERZ catsper channel auxiliary subunit zeta -3.41047
PLK5 polo-like kinase 5 -3.41047
IQCN IQ motif containing N -3.41047
FCRLB Fc receptor-like B -3.41047
CISH cytokine inducible SH2-containing protein -3.41047
MYH7B myosin, heavy chain 7B, cardiac muscle, beta -3.41047
SAXO4 stabilizer of axonemal microtubules 4 -3.41047
SLC25A34 solute carrier family 25, member 34 -3.41047
MYCT1 myc target 1 -3.41047
SFXN3 sideroflexin 3 -3.41047
PRODH proline dehydrogenase (oxidase) 1 -3.41047
TTC16 tetratricopeptide repeat domain 16 -3.41047
TMPRSS3 transmembrane protease, serine 3 -3.41047
CD19 CD19 molecule -3.41047
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 -3.41047
SERPINE3 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3 -3.41047
HKDC1 hexokinase domain containing 1 -3.41047
IL11 interleukin 11 -3.41047
CSTL1 cystatin-like 1 -3.41047
ARRDC2 arrestin domain containing 2 -3.41047
FLI1 Fli-1 proto-oncogene, ETS transcription factor -3.41047
SOWAHD sosondowah ankyrin repeat domain family member D -3.27696
RORA RAR-related orphan receptor A -3.24795
DKKL1 dickkopf-like 1 -3.19903
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b -3.1857
BTBD3 BTB (POZ) domain containing 3 -3.10572
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) -3.01227
C20ORF96 chromosome 20 open reading frame 96 -2.96506
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) -2.82228
C3ORF18 chromosome 3 open reading frame 18 -2.74105
GFER growth factor, augmenter of liver regeneration -2.587
LINGO2 leucine rich repeat and Ig domain containing 2 -2.53849
MDGA2 MAM domain containing glycosylphosphatidylinositol anchor 2 -2.5019
POLD2 polymerase (DNA directed), delta 2, accessory subunit -2.49891
SSUH2 ssu-2 homolog (C. elegans) -2.49375
IL6ST-DT IL6ST divergent transcript -2.49375
TRMT1L tRNA methyltransferase 1 homolog (S. cerevisiae)-like -2.476
METTL25B methyltransferase like 25B -2.47499
ITPRID1 ITPR interacting domain containing 1 -2.46689
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) -2.46689
CYP2C18 cytochrome P450, family 2, subfamily C, polypeptide 18 -2.46689
TBCD tubulin folding cofactor D -2.45756
DLGAP2 discs, large (Drosophila) homolog-associated protein 2 -2.44476
MAP3K3 mitogen-activated protein kinase kinase kinase 3 -2.42959
SNRPB2 small nuclear ribonucleoprotein polypeptide B -2.42959
PAGR1 PAXIP1 associated glutamate-rich protein 1 -2.41824
BMP2 bone morphogenetic protein 2 -2.41463
GEMIN6 gem (nuclear organelle) associated protein 6 -2.37126
PCID2 PCI domain containing 2 -2.36379
IRGQ immunity-related GTPase family, Q -2.35374
POLR2M polymerase (RNA) II (DNA directed) polypeptide M -2.31089
PTGR1 prostaglandin reductase 1 -2.29567
XYLT1 xylosyltransferase I -2.29133
SUSD1 sushi domain containing 1 -2.2913
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12 -2.25377
PTGR3 prostaglandin reductase 3 -2.25377
COL7A1 collagen, type VII, alpha 1 -2.25377
GLIS1 GLIS family zinc finger 1 -2.25377
DNAI1 dynein, axonemal, intermediate chain 1 -2.25377
HMG20A high mobility group 20A -2.24583
RIPPLY2 ripply transcriptional repressor 2 -2.24334
AK8 adenylate kinase 8 -2.24334
GTF3C3 general transcription factor IIIC, polypeptide 3, 102kDa -2.24334
MCM9 minichromosome maintenance complex component 9 -2.24139
BORA bora, aurora kinase A activator -2.20895
ZNF750 zinc finger protein 750 -2.20895
LAG3 lymphocyte-activation gene 3 -2.20895
CYP4Z1 cytochrome P450, family 4, subfamily Z, polypeptide 1 -2.20895
NCAN neurocan -2.20895
PPIA peptidylprolyl isomerase A (cyclophilin A) -2.18471
PAX5 paired box 5 -2.17787
MANEA mannosidase, endo-alpha -2.14881
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 -2.14833
IKZF4 IKAROS family zinc finger 4 (Eos) -2.14742
NTHL1 nth endonuclease III-like 1 (E. coli) -2.14112
PLP2 proteolipid protein 2 (colonic epithelium-enriched) -2.12258
NUDT8 nudix (nucleoside diphosphate linked moiety X)-type motif 8 -2.09456
RUBCN rubicon autophagy regulator -2.08801
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A -2.07685
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 -2.07685
ZNF341 zinc finger protein 341 -2.07537
C5ORF34 chromosome 5 open reading frame 34 -2.07165
SELENOO selenoprotein O -2.06257
LARGE1 LARGE xylosyl- and glucuronyltransferase 1 -2.06257
WASHC5 WASH complex subunit 5 -2.05398
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 -2.04101
CAMKMT calmodulin-lysine N-methyltransferase -2.04032
MZF1 myeloid zinc finger 1 -2.019
ATAD3B ATPase family, AAA domain containing 3B -2.00391
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase -2.00385