MYC Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description v-myc avian myelocytomatosis viral oncogene homolog|The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 4609)
External Link https://ncbi.nlm.nih.gov/gene/4609
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Genes

500 genes differentially expressed following the MYC gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
SSBP2 single-stranded DNA binding protein 2 0.0163807
DLK1 delta-like 1 homolog (Drosophila) 0.0135901
IFI6 interferon, alpha-inducible protein 6 0.0115923
IGFBP5 insulin-like growth factor binding protein 5 0.0115048
SRPX sushi-repeat containing protein, X-linked 0.0114456
PROM1 prominin 1 0.0113453
GSTM3 glutathione S-transferase mu 3 (brain) 0.0110844
SCGB2A2 secretoglobin, family 2A, member 2 0.0105476
CXCL12 chemokine (C-X-C motif) ligand 12 0.00958363
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) 0.00953672
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.00937047
PEG10 paternally expressed 10 0.00922143
AMIGO2 adhesion molecule with Ig-like domain 2 0.00917308
MGP matrix Gla protein 0.00905994
SFRP1 secreted frizzled-related protein 1 0.00905526
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 0.00899734
TUBA1A tubulin, alpha 1a 0.00848566
BHLHE41 basic helix-loop-helix family, member e41 0.00817599
SYNM synemin, intermediate filament protein 0.00796422
PBX3 pre-B-cell leukemia homeobox 3 0.00787847
DPYD dihydropyrimidine dehydrogenase 0.00777158
DKK3 dickkopf WNT signaling pathway inhibitor 3 0.00772773
ALCAM activated leukocyte cell adhesion molecule 0.00769974
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.00765739
CXCL14 chemokine (C-X-C motif) ligand 14 0.0076502
COLEC12 collectin sub-family member 12 0.00756115
TFF1 trefoil factor 1 0.00754771
SCG5 secretogranin V 0.00753172
PBX1 pre-B-cell leukemia homeobox 1 0.00751635
MX1 MX dynamin-like GTPase 1 0.00738256
GNAS GNAS complex locus 0.00735617
FABP4 fatty acid binding protein 4, adipocyte 0.00731658
RECK reversion-inducing-cysteine-rich protein with kazal motifs 0.00730508
TLR4 toll-like receptor 4 0.00724629
MT1X metallothionein 1X 0.00722187
FHL1 four and a half LIM domains 1 0.00720626
GSDME gasdermin E 0.00717823
GOLGA8H golgin A8 family, member H 0.00714309
IFI27 interferon, alpha-inducible protein 27 0.00703709
TLE4 transducin-like enhancer of split 4 0.00700371
MLPH melanophilin 0.00699177
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 0.00698353
CHGB chromogranin B 0.00691974
GREM1 gremlin 1, DAN family BMP antagonist 0.00689736
ECM1 extracellular matrix protein 1 0.00688675
ZFP36L1 ZFP36 ring finger protein-like 1 0.00688271
ACKR3 atypical chemokine receptor 3 0.00688095
PEG3 paternally expressed 3 0.0068105
NRCAM neuronal cell adhesion molecule 0.00680408
KCTD12 potassium channel tetramerization domain containing 12 0.00680134
TFF3 trefoil factor 3 (intestinal) 0.00678106
PENK proenkephalin 0.00677829
THBS1 thrombospondin 1 0.00677693
KRT7 keratin 7, type II 0.00670322
MEN1 multiple endocrine neoplasia I 0.00669683
NAP1L3 nucleosome assembly protein 1-like 3 0.00669185
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 0.00661048
MAB21L2 mab-21-like 2 (C. elegans) 0.00658508
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 0.00658396
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 0.00657616
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 0.00657317
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 0.00655242
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.00650082
C14ORF132 chromosome 14 open reading frame 132 0.00647221
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 0.00640259
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.00639486
TM9SF3 transmembrane 9 superfamily member 3 0.0063569
APOD apolipoprotein D 0.00634526
FBN2 fibrillin 2 0.00632099
MT1F metallothionein 1F 0.0063172
COL14A1 collagen, type XIV, alpha 1 0.00629676
LIPG lipase, endothelial 0.00628592
MT1G metallothionein 1G 0.00627914
SOX9 SRY (sex determining region Y)-box 9 0.0062694
IFI44L interferon-induced protein 44-like 0.00624873
MT1E metallothionein 1E 0.00623305
GALC galactosylceramidase 0.0062245
NELL1 NEL-like 1 (chicken) 0.00617892
MX2 MX dynamin-like GTPase 2 0.00610945
KDM3A lysine (K)-specific demethylase 3A 0.00610282
COL6A3 collagen, type VI, alpha 3 0.00608189
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.00607238
NT5E 5'-nucleotidase, ecto (CD73) 0.00606694
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 0.00606355
SIDT2 SID1 transmembrane family, member 2 0.00603148
DEGS1 delta(4)-desaturase, sphingolipid 1 0.00602061
MRC2 mannose receptor, C type 2 0.00599224
PNMA2 paraneoplastic Ma antigen 2 0.00598647
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 0.0059439
SDC4 syndecan 4 0.00594019
PLAT plasminogen activator, tissue 0.0059199
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 0.00590292
PTN pleiotrophin 0.00590197
LOXL2 lysyl oxidase-like 2 0.00586214
FCGBP Fc fragment of IgG binding protein 0.00586088
MTMR11 myotubularin related protein 11 0.00585642
ARHGAP29 Rho GTPase activating protein 29 0.00585524
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) 0.00582226
GULP1 GULP, engulfment adaptor PTB domain containing 1 0.00581645
IL1B interleukin 1, beta 0.00579518
COG7 component of oligomeric golgi complex 7 0.00578958
RRBP1 ribosome binding protein 1 0.00578758
TKTL1 transketolase-like 1 0.00576837
ZEB1 zinc finger E-box binding homeobox 1 0.00574916
LY75 lymphocyte antigen 75 0.00574008
SCN3A sodium channel, voltage gated, type III alpha subunit 0.00571395
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 0.00570599
RGS5 regulator of G-protein signaling 5 0.00570454
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 0.00570136
FBP1 fructose-1,6-bisphosphatase 1 0.00568339
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 0.00567252
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) 0.00563796
WLS wntless Wnt ligand secretion mediator 0.00563659
CD44 CD44 molecule (Indian blood group) 0.00562091
SOBP sine oculis binding protein homolog (Drosophila) 0.0056087
BDH2 3-hydroxybutyrate dehydrogenase, type 2 0.00560475
SPAG16 sperm associated antigen 16 0.00560458
NID1 nidogen 1 0.00559939
MMRN1 multimerin 1 0.00558859
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 0.00557178
AHR aryl hydrocarbon receptor 0.0055482
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 0.00553201
NLGN4X neuroligin 4, X-linked 0.00552588
NEBL nebulette 0.00551658
COPG1 coatomer protein complex, subunit gamma 1 0.00550901
HLA-B major histocompatibility complex, class I, B 0.00550699
QKI QKI, KH domain containing, RNA binding 0.00547384
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 0.00547196
CD302 CD302 molecule 0.00547004
JCHAIN joining chain of multimeric IgA and IgM 0.00546617
TOX thymocyte selection-associated high mobility group box 0.00543713
SCGB1D2 secretoglobin, family 1D, member 2 0.00543309
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.00541548
VCL vinculin 0.0054135
MT1H metallothionein 1H 0.00541334
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.00541276
CASP2 caspase 2, apoptosis-related cysteine peptidase 0.00540056
MBD1 methyl-CpG binding domain protein 1 0.00536425
PRUNE2 prune homolog 2 (Drosophila) 0.00535017
MKNK2 MAP kinase interacting serine/threonine kinase 2 0.00534273
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor 0.00531121
ARMCX2 armadillo repeat containing, X-linked 2 0.00530863
ZW10 zw10 kinetochore protein 0.00529291
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 0.00526119
VWF von Willebrand factor 0.00526101
SCGB2A1 secretoglobin, family 2A, member 1 0.00523071
ISG15 ISG15 ubiquitin-like modifier 0.00520048
TRPS1 trichorhinophalangeal syndrome I 0.00519572
MYH11 myosin, heavy chain 11, smooth muscle 0.00519306
IFI44 interferon-induced protein 44 0.00519026
VEGFC vascular endothelial growth factor C 0.00518371
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.00516953
TBX3 T-box 3 0.00516317
EDN3 endothelin 3 0.00516037
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 0.00515353
FBN1 fibrillin 1 0.00506843
SPINK1 serine peptidase inhibitor, Kazal type 1 0.00506501
MEF2C myocyte enhancer factor 2C 0.00502635
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 0.00502612
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.00500543
APLP2 amyloid beta (A4) precursor-like protein 2 0.00500504
CYRIA CYFIP related Rac1 interactor A 0.00499998
RRAGD Ras-related GTP binding D 0.00499074
FN1 fibronectin 1 0.00497811
SGCE sarcoglycan, epsilon 0.00497354
BRCA1 breast cancer 1, early onset 0.00495714
BST2 bone marrow stromal cell antigen 2 0.00495683
NRIP1 nuclear receptor interacting protein 1 0.00495498
MYOT myotilin 0.00493858
HEG1 heart development protein with EGF-like domains 1 0.00491456
WNT5A wingless-type MMTV integration site family, member 5A 0.00491415
SH3BGRL SH3 domain binding glutamate-rich protein like 0.00489787
CRABP1 cellular retinoic acid binding protein 1 0.00489471
HMG20B high mobility group 20B 0.00487883
MME membrane metallo-endopeptidase 0.00486919
AHCYL1 adenosylhomocysteinase-like 1 0.00486527
PBLD phenazine biosynthesis-like protein domain containing 0.00485817
NUPR1 nuclear protein, transcriptional regulator, 1 0.00485738
IL1R1 interleukin 1 receptor, type I 0.0048559
IFI16 interferon, gamma-inducible protein 16 0.00483907
RFTN1 raftlin, lipid raft linker 1 0.00483764
CKM creatine kinase, muscle 0.00482117
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 0.00481655
LAMP1 lysosomal-associated membrane protein 1 0.00481306
G0S2 G0/G1 switch 2 0.00481288
AOC1 amine oxidase, copper containing 1 0.00481072
CPQ carboxypeptidase Q 0.00480823
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 0.00478721
ABAT 4-aminobutyrate aminotransferase 0.00478003
NOVA1 neuro-oncological ventral antigen 1 0.00477953
NES nestin 0.00476183
MMP2 matrix metallopeptidase 2 0.00475675
ARMCX1 armadillo repeat containing, X-linked 1 0.00474314
MT1HL1 metallothionein 1H-like 1 0.00473597
HEPH hephaestin 0.00473392
LAMB1 laminin, beta 1 0.00472944
CD93 CD93 molecule 0.00472939
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 0.00470961
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) 0.00470724
MGLL monoglyceride lipase 0.00470576
ANPEP alanyl (membrane) aminopeptidase 0.00469961
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 0.00469801
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 0.00465348
C5AR1 complement component 5a receptor 1 0.00464463
MVP major vault protein 0.0046427
COL15A1 collagen, type XV, alpha 1 0.00463969
TNPO1 transportin 1 0.00463762
ADGRL4 adhesion G protein-coupled receptor L4 0.00463729
STAT1 signal transducer and activator of transcription 1, 91kDa 0.00463443
PADI2 peptidyl arginine deiminase, type II 0.00461884
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 0.00461408
ZEB2 zinc finger E-box binding homeobox 2 0.00460918
TEK TEK tyrosine kinase, endothelial 0.00460115
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.00459298
ZCCHC24 zinc finger, CCHC domain containing 24 0.00458584
CADM1 cell adhesion molecule 1 0.00457739
GIMAP6 GTPase, IMAP family member 6 0.00457407
DCN decorin 0.00456883
PDGFC platelet derived growth factor C 0.00455657
INAVA innate immunity activator 0.00455482
OGN osteoglycin 0.00454039
TSPAN7 tetraspanin 7 0.00453851
TRIM8 tripartite motif containing 8 0.00453745
LMO3 LIM domain only 3 (rhombotin-like 2) 0.00453256
ZFHX4 zinc finger homeobox 4 0.00449943
ZMAT3 zinc finger, matrin-type 3 0.00449821
TUBB2B tubulin, beta 2B class IIb 0.00448868
MT2A metallothionein 2A 0.00448858
ADCY9 adenylate cyclase 9 0.00447768
PLIN3 perilipin 3 0.00447604
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.00447299
INSM1 insulinoma-associated 1 0.00444947
F2R coagulation factor II (thrombin) receptor 0.00444554
DMBT1 deleted in malignant brain tumors 1 0.00444495
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2 0.00441903
IGSF3 immunoglobulin superfamily, member 3 0.0044018
LRRN3 leucine rich repeat neuronal 3 0.0043926
NDRG4 NDRG family member 4 0.00439015
MARCKS myristoylated alanine-rich protein kinase C substrate 0.00438699
G6PD glucose-6-phosphate dehydrogenase 0.00437902
C1ORF115 chromosome 1 open reading frame 115 0.00437308
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) 0.00436419
DST dystonin 0.00436254
TPP1 tripeptidyl peptidase I 0.00435163
AQP1 aquaporin 1 (Colton blood group) 0.00433926
ELAPOR1 endosome-lysosome associated apoptosis and autophagy regulator 1 0.00433257
AGR2 anterior gradient 2 0.00433244
LARP6 La ribonucleoprotein domain family, member 6 0.00432744
THBS4 thrombospondin 4 0.00432494
ALDH9A1 aldehyde dehydrogenase 9 family, member A1 0.00429517

decreased expression

Symbol Name Standardized Value
NUSAP1 nucleolar and spindle associated protein 1 -0.0101059
CKS2 CDC28 protein kinase regulatory subunit 2 -0.0092313
CEMIP cell migration inducing protein, hyaluronan binding -0.00876466
YME1L1 YME1-like 1 ATPase -0.00847057
E2F2 E2F transcription factor 2 -0.00820119
BTG3 BTG family, member 3 -0.00805484
ODC1 ornithine decarboxylase 1 -0.00782083
LTF lactotransferrin -0.00772131
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 -0.00737876
CLDN1 claudin 1 -0.00711429
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 -0.00708373
LYPLA1 lysophospholipase I -0.00697848
PTER phosphotriesterase related -0.0069762
WFDC2 WAP four-disulfide core domain 2 -0.00695643
DUSP2 dual specificity phosphatase 2 -0.00675047
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.00668295
MRPS30 mitochondrial ribosomal protein S30 -0.00655644
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 -0.0064554
MAP7 microtubule-associated protein 7 -0.00645238
HSPE1 heat shock 10kDa protein 1 -0.00640577
CYB5A cytochrome b5 type A (microsomal) -0.00630464
STEAP1 six transmembrane epithelial antigen of the prostate 1 -0.00624025
NME4 NME/NM23 nucleoside diphosphate kinase 4 -0.00604509
CST7 cystatin F (leukocystatin) -0.00602911
CP ceruloplasmin (ferroxidase) -0.00596946
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase -0.00596166
HSPA1A heat shock 70kDa protein 1A -0.00593951
S100A9 S100 calcium binding protein A9 -0.0059272
HP haptoglobin -0.00591927
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -0.00588699
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 -0.00587796
CARMIL1 capping protein regulator and myosin 1 linker 1 -0.00587777
HSPA14 heat shock 70kDa protein 14 -0.00579479
PCLAF PCNA clamp associated factor -0.00577652
ANXA3 annexin A3 -0.00574689
NME1 NME/NM23 nucleoside diphosphate kinase 1 -0.00572718
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 -0.00570258
YAP1 Yes-associated protein 1 -0.00566993
TPM4 tropomyosin 4 -0.00565443
PNO1 partner of NOB1 homolog (S. cerevisiae) -0.00563169
CYC1 cytochrome c-1 -0.00554817
PTGER3 prostaglandin E receptor 3 (subtype EP3) -0.00552439
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) -0.00552257
SRSF10 serine/arginine-rich splicing factor 10 -0.00546253
COPS2 COP9 signalosome subunit 2 -0.00543761
RCN2 reticulocalbin 2, EF-hand calcium binding domain -0.00536655
MYO1B myosin IB -0.0053637
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3 -0.00533794
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -0.00531241
CXCL11 chemokine (C-X-C motif) ligand 11 -0.0052405
EML4 echinoderm microtubule associated protein like 4 -0.00523662
RPL10 ribosomal protein L10 -0.00521081
PRDX2 peroxiredoxin 2 -0.00520912
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H -0.00518107
CXCR4 chemokine (C-X-C motif) receptor 4 -0.00518045
IDI1 isopentenyl-diphosphate delta isomerase 1 -0.00517448
THAP11 THAP domain containing 11 -0.00516445
MRPL19 mitochondrial ribosomal protein L19 -0.00506753
ANXA2 annexin A2 -0.00505024
SRSF7 serine/arginine-rich splicing factor 7 -0.00504507
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 -0.00504167
RAB5IF RAB5 interacting factor -0.00501834
EIF4A3 eukaryotic translation initiation factor 4A3 -0.00501828
MMP12 matrix metallopeptidase 12 -0.00498481
PNN pinin, desmosome associated protein -0.00497128
ELANE elastase, neutrophil expressed -0.0049652
PHACTR2 phosphatase and actin regulator 2 -0.00496255
SCEL sciellin -0.00495342
ASNS asparagine synthetase (glutamine-hydrolyzing) -0.0049143
RSL24D1 ribosomal L24 domain containing 1 -0.00490924
TFAM transcription factor A, mitochondrial -0.00490889
ATP5F1C ATP synthase F1 subunit gamma -0.00489888
ELOC elongin C -0.00486712
CAPN1 calpain 1, (mu/I) large subunit -0.00486532
GADD45G growth arrest and DNA-damage-inducible, gamma -0.00486499
TCP1 t-complex 1 -0.00485602
TMEM14B transmembrane protein 14B -0.0048555
MTPAP mitochondrial poly(A) polymerase -0.00484945
PDHX pyruvate dehydrogenase complex, component X -0.00483868
CD8A CD8a molecule -0.00483103
EIF3J eukaryotic translation initiation factor 3, subunit J -0.0048257
NOP16 NOP16 nucleolar protein -0.00481383
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) -0.00481342
CPA3 carboxypeptidase A3 (mast cell) -0.00481173
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1 -0.00480111
TFRC transferrin receptor -0.00479713
CLNS1A chloride channel, nucleotide-sensitive, 1A -0.00479185
HSPD1 heat shock 60kDa protein 1 (chaperonin) -0.00478782
PDCD10 programmed cell death 10 -0.00477173
GLRX3 glutaredoxin 3 -0.00476904
ESRP1 epithelial splicing regulatory protein 1 -0.00475687
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) -0.0047444
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 -0.00473424
HOXB2 homeobox B2 -0.00472433
KIAA0125 KIAA0125 -0.00471975
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 -0.00471833
SFPQ splicing factor proline/glutamine-rich -0.0047122
H1-0 H1.0 linker histone -0.00469757
RANBP1 RAN binding protein 1 -0.00468744
NCK1 NCK adaptor protein 1 -0.00467563
CCL20 chemokine (C-C motif) ligand 20 -0.00467487
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa -0.00467417
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 -0.00466965
CREBZF CREB/ATF bZIP transcription factor -0.00466168
SELENOT selenoprotein T -0.00465264
PUF60 poly-U binding splicing factor 60KDa -0.004622
S100A2 S100 calcium binding protein A2 -0.00462075
KANSL2 KAT8 regulatory NSL complex subunit 2 -0.00458349
GZMK granzyme K (granzyme 3; tryptase II) -0.00455877
NR4A2 nuclear receptor subfamily 4, group A, member 2 -0.00455192
MNDA myeloid cell nuclear differentiation antigen -0.00454007
CXCL10 chemokine (C-X-C motif) ligand 10 -0.00453455
CENPX centromere protein X -0.00452348
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 -0.00451767
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX) -0.00451578
CDCA4 cell division cycle associated 4 -0.00451211
TPD52L1 tumor protein D52-like 1 -0.00451045
LRRC15 leucine rich repeat containing 15 -0.0045082
ITGB1BP1 integrin beta 1 binding protein 1 -0.00449971
MPZL2 myelin protein zero-like 2 -0.00449788
PON3 paraoxonase 3 -0.00445545
ECHDC3 enoyl CoA hydratase domain containing 3 -0.00444758
NMD3 NMD3 ribosome export adaptor -0.00444231
RAB32 RAB32, member RAS oncogene family -0.00441929
POP7 processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae) -0.00441603
MMP9 matrix metallopeptidase 9 -0.00440487
GRPEL1 GrpE-like 1, mitochondrial (E. coli) -0.0043835
RIDA reactive intermediate imine deaminase A homolog -0.00437843
CXCL13 chemokine (C-X-C motif) ligand 13 -0.00437362
NCAPD3 non-SMC condensin II complex, subunit D3 -0.00437278
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) -0.00437235
HIST1H2AE histone cluster 1, H2ae -0.00436905
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 -0.00436896
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative) -0.00436644
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing -0.00436544
UPK1B uroplakin 1B -0.00436249
RBM38 RNA binding motif protein 38 -0.00436245
ZNRD2 zinc ribbon domain containing 2 -0.00435732
PTS 6-pyruvoyltetrahydropterin synthase -0.00435684
WT1 Wilms tumor 1 -0.0043543
NDC1 NDC1 transmembrane nucleoporin -0.00435144
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) -0.00434569
SNRPE small nuclear ribonucleoprotein polypeptide E -0.00433644
CORO1C coronin, actin binding protein, 1C -0.00433084
SLCO4A1 solute carrier organic anion transporter family, member 4A1 -0.004318
GATA2 GATA binding protein 2 -0.00431643
CGA glycoprotein hormones, alpha polypeptide -0.00430886
SPTAN1 spectrin, alpha, non-erythrocytic 1 -0.00430678
MRPS28 mitochondrial ribosomal protein S28 -0.00430612
FOLR1 folate receptor 1 (adult) -0.00430444
MCM5 minichromosome maintenance complex component 5 -0.00430102
TRAM1 translocation associated membrane protein 1 -0.00429697
ATG5 autophagy related 5 -0.0042891
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) -0.00427211
ETF1 eukaryotic translation termination factor 1 -0.00426723
ACP1 acid phosphatase 1, soluble -0.00426537
H2AX H2A.X variant histone -0.00426083
FRS2 fibroblast growth factor receptor substrate 2 -0.00425477
TLCD3A TLC domain containing 3A -0.0042531
TMEM70 transmembrane protein 70 -0.00425178
SMIM8 small integral membrane protein 8 -0.00424457
SPTSSA serine palmitoyltransferase, small subunit A -0.00424121
NCBP2 nuclear cap binding protein subunit 2, 20kDa -0.00422616
ATP5PF ATP synthase peripheral stalk subunit F6 -0.00421284
SEPP1 selenoprotein P, plasma, 1 -0.00421185
GAB2 GRB2-associated binding protein 2 -0.00420594
CCDC86 coiled-coil domain containing 86 -0.00420083
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -0.00419763
NIT2 nitrilase family, member 2 -0.00419739
HPN hepsin -0.00419619
TSPAN6 tetraspanin 6 -0.00418581
MRPL13 mitochondrial ribosomal protein L13 -0.00417616
ITGA6 integrin, alpha 6 -0.00416981
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -0.00416837
ELAVL1 ELAV like RNA binding protein 1 -0.00416516
GLUL glutamate-ammonia ligase -0.00415347
MRPS7 mitochondrial ribosomal protein S7 -0.00414177
CFB complement factor B -0.00413351
CCNC cyclin C -0.00413193
MRPL11 mitochondrial ribosomal protein L11 -0.00412874
SUMO3 small ubiquitin-like modifier 3 -0.00412
TRIP6 thyroid hormone receptor interactor 6 -0.00411524
FOXC1 forkhead box C1 -0.00411479
MRPL18 mitochondrial ribosomal protein L18 -0.0041141
MRPL42 mitochondrial ribosomal protein L42 -0.00411168
TPSAB1 tryptase alpha/beta 1 -0.00410617
TARP TCR gamma alternate reading frame protein -0.00410386
KIF5B kinesin family member 5B -0.0041003
ELL2 elongation factor, RNA polymerase II, 2 -0.00409482
ARMC1 armadillo repeat containing 1 -0.00409331
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 -0.00408725
GTF2A2 general transcription factor IIA, 2, 12kDa -0.00407905
DCTN6 dynactin 6 -0.00405511
HIST3H2A histone cluster 3, H2a -0.00405318
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 -0.00404954
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 -0.00404333
MSMB microseminoprotein, beta- -0.00403776
TCTA T-cell leukemia translocation altered -0.00401557
KLK7 kallikrein-related peptidase 7 -0.00401245
HSPA6 heat shock 70kDa protein 6 (HSP70B') -0.00400495
LGALS2 lectin, galactoside-binding, soluble, 2 -0.00399634
MCM10 minichromosome maintenance complex component 10 -0.00399341
NKG7 natural killer cell granule protein 7 -0.00398483
MED17 mediator complex subunit 17 -0.00397674
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) -0.00397144
TMEM126B transmembrane protein 126B -0.0039714
HIST1H2BD histone cluster 1, H2bd -0.0039621
SIK1 salt-inducible kinase 1 -0.00395973
GCH1 GTP cyclohydrolase 1 -0.00395352
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -0.00395309
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 -0.00395297
SFTPA2 surfactant protein A2 -0.00395137
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5 -0.00394274
HMGB3 high mobility group box 3 -0.00392939
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) -0.00392113
TPRKB TP53RK binding protein -0.00391897
COX17 COX17 cytochrome c oxidase copper chaperone -0.00391808
S100A8 S100 calcium binding protein A8 -0.00391626
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 -0.00391621
NIP7 NIP7, nucleolar pre-rRNA processing protein -0.00391283
HOXB7 homeobox B7 -0.00391047
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase -0.00390869
ANAPC15 anaphase promoting complex subunit 15 -0.00390641
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.00390565
MOB4 MOB family member 4, phocein -0.00390005
S100A12 S100 calcium binding protein A12 -0.00389037
ANGPT1 angiopoietin 1 -0.00388941
PFDN4 prefoldin subunit 4 -0.0038885
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -0.00388783
COMMD10 COMM domain containing 10 -0.00388297
PAK1IP1 PAK1 interacting protein 1 -0.00387575
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.00385219
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O -0.00384027
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.00383428
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12) -0.0038318
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6 -0.0038293
RFC4 replication factor C (activator 1) 4, 37kDa -0.00382362
CXCL9 chemokine (C-X-C motif) ligand 9 -0.0038154
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 -0.00381241
FASTKD3 FAST kinase domains 3 -0.0038099
NNT nicotinamide nucleotide transhydrogenase -0.00380687
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa -0.00380027
MPO myeloperoxidase -0.00379305
ATAD2 ATPase family, AAA domain containing 2 -0.00379215
SRP72 signal recognition particle 72kDa -0.00379087
PKP2 plakophilin 2 -0.00377883
PRF1 perforin 1 (pore forming protein) -0.0037725
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1 -0.00376922
FZD5 frizzled class receptor 5 -0.00376503
TXNL4A thioredoxin-like 4A -0.00375684