MYC Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description v-myc avian myelocytomatosis viral oncogene homolog|The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 4609)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/MORF_MYC
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Genes

79 co-expressed genes for MYC from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
AQP5 aquaporin 5
BCL2 B-cell CLL/lymphoma 2
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CD6 CD6 molecule
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CEP135 centrosomal protein 135kDa
CLOCK clock circadian regulator
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
CRHR1 corticotropin releasing hormone receptor 1
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1
DAPK2 death-associated protein kinase 2
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DPT dermatopontin
ESR1 estrogen receptor 1
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FAM189A2 family with sequence similarity 189, member A2
FDXR ferredoxin reductase
GLE1 GLE1 RNA export mediator
GRIK5 glutamate receptor, ionotropic, kainate 5
GRIP2 glutamate receptor interacting protein 2
GRK4 G protein-coupled receptor kinase 4
HAUS5 HAUS augmin-like complex, subunit 5
HOXD4 homeobox D4
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
IPCEF1 interaction protein for cytohesin exchange factors 1
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KAT8 K(lysine) acetyltransferase 8
KIAA0195 KIAA0195
KLHL18 kelch-like family member 18
KRT1 keratin 1, type II
KRT33A keratin 33A, type I
KRT86 keratin 86, type II
LRRC48 leucine rich repeat containing 48
LTBP4 latent transforming growth factor beta binding protein 4
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MLN motilin
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
MSX1 msh homeobox 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYO9B myosin IXB
NCKIPSD NCK interacting protein with SH3 domain
NFIC nuclear factor I/C (CCAAT-binding transcription factor)
NFRKB nuclear factor related to kappaB binding protein
PAX7 paired box 7
PAX8 paired box 8
PAX9 paired box 9
PAXIP1 PAX interacting (with transcription-activation domain) protein 1
PIGB phosphatidylinositol glycan anchor biosynthesis, class B
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PRSS16 protease, serine, 16 (thymus)
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RBBP8 retinoblastoma binding protein 8
RFC5 replication factor C (activator 1) 5, 36.5kDa
RPH3A rabphilin 3A
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
SCAPER S-phase cyclin A-associated protein in the ER
SIX3 SIX homeobox 3
SLC13A2 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC22A24 solute carrier family 22, member 24
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC4A3 solute carrier family 4 (anion exchanger), member 3
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SRSF8 serine/arginine-rich splicing factor 8
SSTR5 somatostatin receptor 5
STK17A serine/threonine kinase 17a
TBX5 T-box 5
TGOLN2 trans-golgi network protein 2
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF330 zinc finger protein 330
ZNF592 zinc finger protein 592