MYCN Gene Set

Dataset JASPAR Predicted Transcription Factor Targets
Category genomics
Type transcription factor
Description v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog|This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014] (NCBI Entrez Gene Database, 4613)
External Link http://www.ncbi.nlm.nih.gov/gene/4613
Similar Terms
Downloads & Tools

Genes

12 target genes of the MYCN transcription factor predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset.

Symbol Name
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
CCL28 chemokine (C-C motif) ligand 28
PDIA2 protein disulfide isomerase family A, member 2
PRSS35 protease, serine, 35
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
SOCS7 suppressor of cytokine signaling 7
SPTLC1 serine palmitoyltransferase, long chain base subunit 1
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TMC8 transmembrane channel-like 8
VAMP7 vesicle-associated membrane protein 7
ZNF830 zinc finger protein 830