| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog|This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014] (NCBI Entrez Gene Database, 4613) |
| External Link | https://ncbi.nlm.nih.gov/gene/4613 |
| Similar Terms | |
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498 genes differentially expressed following the MYCN gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IFI27 | interferon, alpha-inducible protein 27 | 0.0186408 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0168444 |
| MX1 | MX dynamin-like GTPase 1 | 0.0155038 |
| S100P | S100 calcium binding protein P | 0.0144876 |
| ANXA3 | annexin A3 | 0.0140193 |
| LTF | lactotransferrin | 0.0140117 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 0.013847 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0135531 |
| RGCC | regulator of cell cycle | 0.0131734 |
| KRT13 | keratin 13, type I | 0.0130876 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 0.0129534 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0128423 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.0116819 |
| KRT19 | keratin 19, type I | 0.011678 |
| TGM2 | transglutaminase 2 | 0.0116382 |
| IFI44L | interferon-induced protein 44-like | 0.0113982 |
| BMP4 | bone morphogenetic protein 4 | 0.0112392 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | 0.0110706 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | 0.0110331 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.0108439 |
| MSX1 | msh homeobox 1 | 0.0107531 |
| USP18 | ubiquitin specific peptidase 18 | 0.0107089 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0105384 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.0103974 |
| MYBPC1 | myosin binding protein C, slow type | 0.0103773 |
| MMP12 | matrix metallopeptidase 12 | 0.0103381 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 | 0.0103075 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0103024 |
| OPTN | optineurin | 0.0103007 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.0102998 |
| ATF3 | activating transcription factor 3 | 0.0101886 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | 0.0101738 |
| MALL | mal, T-cell differentiation protein-like | 0.0101064 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.00998654 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.00997869 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.00997684 |
| BCL2A1 | BCL2-related protein A1 | 0.00990641 |
| IQCG | IQ motif containing G | 0.00987874 |
| BAG2 | BCL2-associated athanogene 2 | 0.00987549 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.00986219 |
| MLF1 | myeloid leukemia factor 1 | 0.00971771 |
| NEK7 | NIMA-related kinase 7 | 0.00964885 |
| TSPAN1 | tetraspanin 1 | 0.00957981 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.00953113 |
| SPRR3 | small proline-rich protein 3 | 0.0095048 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | 0.0094803 |
| PLSCR1 | phospholipid scramblase 1 | 0.00933259 |
| IRF6 | interferon regulatory factor 6 | 0.00929833 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.00926433 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.00925893 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.00922037 |
| IFI44 | interferon-induced protein 44 | 0.00921164 |
| CD14 | CD14 molecule | 0.00921 |
| ITGA6 | integrin, alpha 6 | 0.00917637 |
| TMC5 | transmembrane channel-like 5 | 0.00907756 |
| CDH3 | cadherin 3, type 1, P-cadherin (placental) | 0.00898408 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.00891581 |
| NEBL | nebulette | 0.008849 |
| CTSS | cathepsin S | 0.00881711 |
| CLCA4 | chloride channel accessory 4 | 0.00878921 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha | 0.00877115 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.00873397 |
| LY6D | lymphocyte antigen 6 complex, locus D | 0.00868856 |
| TNNC1 | troponin C type 1 (slow) | 0.00866573 |
| THEMIS2 | thymocyte selection associated family member 2 | 0.00865096 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 0.00861773 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.00858329 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 | 0.00857274 |
| KDELR3 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 | 0.00856938 |
| IFI35 | interferon-induced protein 35 | 0.00854042 |
| ITM2C | integral membrane protein 2C | 0.00849258 |
| MUC4 | mucin 4, cell surface associated | 0.00847872 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | 0.00839886 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.008398 |
| TMPRSS4 | transmembrane protease, serine 4 | 0.00837523 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | 0.00833973 |
| MYRF | myelin regulatory factor | 0.00833186 |
| WIF1 | WNT inhibitory factor 1 | 0.00828098 |
| ANXA1 | annexin A1 | 0.00823641 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.00821877 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0081931 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 0.00817445 |
| CTTN | cortactin | 0.00814892 |
| HSPA8 | heat shock 70kDa protein 8 | 0.00811662 |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | 0.00809802 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | 0.00807427 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | 0.0080511 |
| TRAM1 | translocation associated membrane protein 1 | 0.00805072 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.00805064 |
| CD163 | CD163 molecule | 0.00799954 |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta | 0.00798302 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | 0.00796973 |
| LCN2 | lipocalin 2 | 0.00792965 |
| PLTP | phospholipid transfer protein | 0.00789334 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 0.00788522 |
| SLN | sarcolipin | 0.00788021 |
| ATG5 | autophagy related 5 | 0.00787106 |
| CLDND1 | claudin domain containing 1 | 0.00786195 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.00784703 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 0.00782716 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.00779344 |
| XAF1 | XIAP associated factor 1 | 0.00779114 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.00776589 |
| ABLIM1 | actin binding LIM protein 1 | 0.00775977 |
| ADA | adenosine deaminase | 0.00775275 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.00774608 |
| EMP1 | epithelial membrane protein 1 | 0.00771928 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | 0.00771664 |
| ME2 | malic enzyme 2, NAD(+)-dependent, mitochondrial | 0.00770212 |
| MAGEA3 | melanoma antigen family A3 | 0.00767996 |
| ARNTL2 | aryl hydrocarbon receptor nuclear translocator-like 2 | 0.00765864 |
| SRPX2 | sushi-repeat containing protein, X-linked 2 | 0.0076498 |
| RGS10 | regulator of G-protein signaling 10 | 0.00763969 |
| CD53 | CD53 molecule | 0.00763342 |
| PRF1 | perforin 1 (pore forming protein) | 0.00762307 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | 0.00760669 |
| EMX2 | empty spiracles homeobox 2 | 0.00753301 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | 0.00752968 |
| MMP7 | matrix metallopeptidase 7 | 0.00747328 |
| IFT57 | intraflagellar transport 57 | 0.00745391 |
| FBN1 | fibrillin 1 | 0.00745237 |
| BTG2 | BTG family, member 2 | 0.00744507 |
| SINHCAF | SIN3-HDAC complex associated factor | 0.00742071 |
| SPON1 | spondin 1, extracellular matrix protein | 0.00741455 |
| C1S | complement component 1, s subcomponent | 0.00741235 |
| AIM2 | absent in melanoma 2 | 0.00740513 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | 0.0073954 |
| CCL14 | chemokine (C-C motif) ligand 14 | 0.00729829 |
| PSAT1 | phosphoserine aminotransferase 1 | 0.0072702 |
| MGP | matrix Gla protein | 0.0072651 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | 0.00724125 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | 0.0072372 |
| TPM4 | tropomyosin 4 | 0.00721782 |
| VSIG4 | V-set and immunoglobulin domain containing 4 | 0.00721019 |
| S100A12 | S100 calcium binding protein A12 | 0.00719122 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | 0.00718007 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.0071733 |
| MAPK1 | mitogen-activated protein kinase 1 | 0.00714322 |
| MT1M | metallothionein 1M | 0.00711813 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | 0.00711537 |
| RNASET2 | ribonuclease T2 | 0.00709414 |
| KLK10 | kallikrein-related peptidase 10 | 0.00703434 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | 0.00701542 |
| MSMB | microseminoprotein, beta- | 0.0070087 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.00700326 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | 0.00698789 |
| CNTN1 | contactin 1 | 0.00695954 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 0.0069392 |
| WSB2 | WD repeat and SOCS box containing 2 | 0.00693102 |
| RAB25 | RAB25, member RAS oncogene family | 0.00692275 |
| MMP10 | matrix metallopeptidase 10 | 0.0069178 |
| MPO | myeloperoxidase | 0.00691004 |
| VAMP5 | vesicle-associated membrane protein 5 | 0.0069087 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.00690238 |
| RCAN1 | regulator of calcineurin 1 | 0.00689889 |
| RAB5C | RAB5C, member RAS oncogene family | 0.00687482 |
| TPPP3 | tubulin polymerization-promoting protein family member 3 | 0.00686689 |
| MECOM | MDS1 and EVI1 complex locus | 0.00685994 |
| KLK11 | kallikrein-related peptidase 11 | 0.00684502 |
| MME | membrane metallo-endopeptidase | 0.00684143 |
| SH3BGR | SH3 domain binding glutamate-rich protein | 0.0068206 |
| KLF6 | Kruppel-like factor 6 | 0.00679294 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.00677206 |
| TMOD3 | tropomodulin 3 (ubiquitous) | 0.00676117 |
| GDI2 | GDP dissociation inhibitor 2 | 0.00675374 |
| MAL | mal, T-cell differentiation protein | 0.00675358 |
| NIBAN1 | niban apoptosis regulator 1 | 0.0067422 |
| HBB | hemoglobin, beta | 0.0067306 |
| GPD1L | glycerol-3-phosphate dehydrogenase 1-like | 0.00672126 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.00671723 |
| NCOA4 | nuclear receptor coactivator 4 | 0.00671289 |
| EGFL6 | EGF-like-domain, multiple 6 | 0.00670716 |
| MX2 | MX dynamin-like GTPase 2 | 0.00670239 |
| PLEK2 | pleckstrin 2 | 0.00669966 |
| IL1RN | interleukin 1 receptor antagonist | 0.00667671 |
| GYPC | glycophorin C (Gerbich blood group) | 0.006668 |
| DLST | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) | 0.00666561 |
| DAZAP2 | DAZ associated protein 2 | 0.00666234 |
| SIK1 | salt-inducible kinase 1 | 0.00666172 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | 0.00662309 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | 0.00662086 |
| FABP6 | fatty acid binding protein 6, ileal | 0.00659 |
| PLAUR | plasminogen activator, urokinase receptor | 0.00657112 |
| HCRT | hypocretin (orexin) neuropeptide precursor | 0.00656938 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | 0.00655792 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | 0.00654576 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | 0.00653125 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.00652366 |
| SCEL | sciellin | 0.00650021 |
| PSAP | prosaposin | 0.00649585 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.00649117 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.00648703 |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist | 0.00646887 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.00646412 |
| TSPAN8 | tetraspanin 8 | 0.00643553 |
| PRKCH | protein kinase C, eta | 0.0064344 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | 0.00643263 |
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | 0.00642421 |
| CD48 | CD48 molecule | 0.00641727 |
| CETN2 | centrin, EF-hand protein, 2 | 0.00641359 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.00640779 |
| HOPX | HOP homeobox | 0.00639236 |
| UPK1B | uroplakin 1B | 0.00639145 |
| LXN | latexin | 0.00638067 |
| S100A7 | S100 calcium binding protein A7 | 0.00637913 |
| BPGM | 2,3-bisphosphoglycerate mutase | 0.00637681 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | 0.00637348 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | 0.00636335 |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 | 0.00635919 |
| MYO1C | myosin IC | 0.00635462 |
| CAPRIN1 | cell cycle associated protein 1 | 0.00634686 |
| CLIC5 | chloride intracellular channel 5 | 0.00634362 |
| FZD6 | frizzled class receptor 6 | 0.00632752 |
| BMP7 | bone morphogenetic protein 7 | 0.00629908 |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) | 0.00629589 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.00627778 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | 0.00627427 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.00626148 |
| SLC4A1 | solute carrier family 4 (anion exchanger), member 1 (Diego blood group) | 0.00625783 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.00623841 |
| TMPRSS2 | transmembrane protease, serine 2 | 0.00621775 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | 0.00619364 |
| HBEGF | heparin-binding EGF-like growth factor | 0.00619231 |
| HLA-B | major histocompatibility complex, class I, B | 0.00619078 |
| SELENOT | selenoprotein T | 0.00617592 |
| PRNP | prion protein | 0.00616631 |
| ELAVL1 | ELAV like RNA binding protein 1 | 0.00614871 |
| PDAP1 | PDGFA associated protein 1 | 0.00614216 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | 0.0061381 |
| TICAM1 | toll-like receptor adaptor molecule 1 | 0.00610986 |
| LAMA2 | laminin, alpha 2 | 0.00610349 |
| RAD23A | RAD23 homolog A (S. cerevisiae) | 0.006101 |
| EXOC5 | exocyst complex component 5 | 0.00609942 |
| CHKB | choline kinase beta | 0.00608734 |
| RAB23 | RAB23, member RAS oncogene family | 0.00608618 |
| BTG3 | BTG family, member 3 | 0.00605334 |
| COLEC12 | collectin sub-family member 12 | 0.00605024 |
| TMEM230 | transmembrane protein 230 | 0.00604521 |
| ARAP2 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 | 0.0060343 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.00603207 |
| HPGDS | hematopoietic prostaglandin D synthase | 0.00603178 |
| GLUL | glutamate-ammonia ligase | 0.00602244 |
| DUSP22 | dual specificity phosphatase 22 | 0.00601401 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.00601111 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | 0.00598361 |
| PDCD10 | programmed cell death 10 | 0.00597209 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | 0.00596268 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.00596107 |
| FABP7 | fatty acid binding protein 7, brain | 0.00595799 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SSBP2 | single-stranded DNA binding protein 2 | -0.017022 |
| NPY1R | neuropeptide Y receptor Y1 | -0.0151594 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.0144321 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -0.0134814 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.0133828 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.0124581 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -0.0123101 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | -0.0122336 |
| CPB1 | carboxypeptidase B1 (tissue) | -0.0119884 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | -0.0118798 |
| LDOC1 | leucine zipper, down-regulated in cancer 1 | -0.0108182 |
| PEG10 | paternally expressed 10 | -0.0108176 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | -0.0104615 |
| ZNF160 | zinc finger protein 160 | -0.0104133 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -0.010389 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0103407 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | -0.00996313 |
| NID2 | nidogen 2 (osteonidogen) | -0.00991227 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | -0.00971599 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) | -0.0095574 |
| CGA | glycoprotein hormones, alpha polypeptide | -0.0094074 |
| PXDN | peroxidasin | -0.00936606 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.00932487 |
| DCLK1 | doublecortin-like kinase 1 | -0.00932282 |
| FBXW12 | F-box and WD repeat domain containing 12 | -0.00921375 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | -0.00908626 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 | -0.00905376 |
| KCNE4 | potassium channel, voltage gated subfamily E regulatory beta subunit 4 | -0.00904262 |
| ARHGEF40 | Rho guanine nucleotide exchange factor (GEF) 40 | -0.00900743 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.00894778 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | -0.00892221 |
| NOTCH2NL | notch 2 N-terminal like | -0.00882693 |
| ZNF721 | zinc finger protein 721 | -0.00873282 |
| TSPAN12 | tetraspanin 12 | -0.00862908 |
| CCL19 | chemokine (C-C motif) ligand 19 | -0.00862844 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | -0.00862696 |
| HSPA1A | heat shock 70kDa protein 1A | -0.00859201 |
| SQSTM1 | sequestosome 1 | -0.0085716 |
| PRR11 | proline rich 11 | -0.00855262 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | -0.00850593 |
| TSPAN4 | tetraspanin 4 | -0.00841941 |
| HOXC10 | homeobox C10 | -0.00841707 |
| OBSL1 | obscurin-like 1 | -0.00840874 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.00839113 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | -0.00833915 |
| SLCO3A1 | solute carrier organic anion transporter family, member 3A1 | -0.00832903 |
| SCG5 | secretogranin V | -0.00810995 |
| ISYNA1 | inositol-3-phosphate synthase 1 | -0.00801155 |
| PLK2 | polo-like kinase 2 | -0.00800563 |
| PLAAT3 | phospholipase A and acyltransferase 3 | -0.00796835 |
| MSN | moesin | -0.00796397 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.00793845 |
| METTL17 | methyltransferase like 17 | -0.0079147 |
| SLCO4C1 | solute carrier organic anion transporter family, member 4C1 | -0.00781055 |
| CCNF | cyclin F | -0.00774611 |
| TMEM45A | transmembrane protein 45A | -0.00764845 |
| RBPMS | RNA binding protein with multiple splicing | -0.00764361 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.00762499 |
| CLU | clusterin | -0.00762031 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.00758262 |
| KRT14 | keratin 14, type I | -0.00751443 |
| DNAJB14 | DnaJ (Hsp40) homolog, subfamily B, member 14 | -0.00750425 |
| PLXNC1 | plexin C1 | -0.00750277 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -0.0075023 |
| RET | ret proto-oncogene | -0.00747602 |
| ADCY9 | adenylate cyclase 9 | -0.00745635 |
| CCL21 | chemokine (C-C motif) ligand 21 | -0.00738499 |
| HAUS2 | HAUS augmin-like complex, subunit 2 | -0.00738318 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | -0.00736425 |
| ZNF611 | zinc finger protein 611 | -0.00735257 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -0.00734926 |
| TNC | tenascin C | -0.00734074 |
| SARAF | store-operated calcium entry-associated regulatory factor | -0.00733411 |
| MFSD10 | major facilitator superfamily domain containing 10 | -0.00732796 |
| TPSAB1 | tryptase alpha/beta 1 | -0.00722712 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 | -0.00718367 |
| FASN | fatty acid synthase | -0.00717441 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.00716144 |
| LEPROTL1 | leptin receptor overlapping transcript-like 1 | -0.00715941 |
| NME3 | NME/NM23 nucleoside diphosphate kinase 3 | -0.00714971 |
| GOLGA8H | golgin A8 family, member H | -0.00712732 |
| NTS | neurotensin | -0.00710614 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.00705036 |
| CTSA | cathepsin A | -0.00697216 |
| ADCY1 | adenylate cyclase 1 (brain) | -0.00695407 |
| PRKCSH | protein kinase C substrate 80K-H | -0.00694372 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 | -0.00693788 |
| DCT | dopachrome tautomerase | -0.00691879 |
| GAL | galanin/GMAP prepropeptide | -0.00689291 |
| POLR1B | polymerase (RNA) I polypeptide B, 128kDa | -0.00689152 |
| FXYD2 | FXYD domain containing ion transport regulator 2 | -0.00688819 |
| PDZK1 | PDZ domain containing 1 | -0.00687109 |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 | -0.006839 |
| NANOG | Nanog homeobox | -0.00683501 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | -0.00683382 |
| DNASE1L3 | deoxyribonuclease I-like 3 | -0.0068042 |
| BAHCC1 | BAH domain and coiled-coil containing 1 | -0.00679597 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | -0.00679425 |
| IRX5 | iroquois homeobox 5 | -0.00679239 |
| PDGFD | platelet derived growth factor D | -0.00679154 |
| TCTA | T-cell leukemia translocation altered | -0.00678987 |
| ENG | endoglin | -0.00676821 |
| GOLGA8A | golgin A8 family, member A | -0.0067554 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.00672271 |
| GGCT | gamma-glutamylcyclotransferase | -0.00669102 |
| LONP2 | lon peptidase 2, peroxisomal | -0.00666567 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.00665842 |
| LRP2 | low density lipoprotein receptor-related protein 2 | -0.00665141 |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) | -0.00662348 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | -0.00661592 |
| MBD1 | methyl-CpG binding domain protein 1 | -0.0066129 |
| NOTCH1 | notch 1 | -0.0065657 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.00656489 |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 | -0.00656293 |
| KPNA6 | karyopherin alpha 6 (importin alpha 7) | -0.00654026 |
| SPATA20 | spermatogenesis associated 20 | -0.00653032 |
| KIAA0930 | KIAA0930 | -0.00650281 |
| RGS16 | regulator of G-protein signaling 16 | -0.00646651 |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) | -0.00645657 |
| BEX1 | brain expressed, X-linked 1 | -0.00643879 |
| BCAT2 | branched chain amino-acid transaminase 2, mitochondrial | -0.00643513 |
| NVL | nuclear VCP-like | -0.00641746 |
| ZNF91 | zinc finger protein 91 | -0.00637097 |
| ZNF587 | zinc finger protein 587 | -0.00636736 |
| KRAS | Kirsten rat sarcoma viral oncogene homolog | -0.00633773 |
| STK10 | serine/threonine kinase 10 | -0.0063376 |
| VCAM1 | vascular cell adhesion molecule 1 | -0.00632339 |
| HMGN5 | high mobility group nucleosome binding domain 5 | -0.00631588 |
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | -0.00630915 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | -0.00630705 |
| CFP | complement factor properdin | -0.00630123 |
| CTSD | cathepsin D | -0.00628388 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 | -0.00627224 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial | -0.0062534 |
| FAM110B | family with sequence similarity 110, member B | -0.0062248 |
| SLC39A6 | solute carrier family 39 (zinc transporter), member 6 | -0.00620176 |
| TECR | trans-2,3-enoyl-CoA reductase | -0.00619339 |
| PLXND1 | plexin D1 | -0.00617652 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | -0.0061748 |
| SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A | -0.00616259 |
| ALDH8A1 | aldehyde dehydrogenase 8 family, member A1 | -0.00612684 |
| PGRMC2 | progesterone receptor membrane component 2 | -0.00610982 |
| DHCR24 | 24-dehydrocholesterol reductase | -0.00609312 |
| COL11A1 | collagen, type XI, alpha 1 | -0.00608106 |
| PMEL | premelanosome protein | -0.00607012 |
| PLK1 | polo-like kinase 1 | -0.0060693 |
| PTK2B | protein tyrosine kinase 2 beta | -0.00606758 |
| ZNF217 | zinc finger protein 217 | -0.00605219 |
| NAV2 | neuron navigator 2 | -0.00604896 |
| PLXNB2 | plexin B2 | -0.00604706 |
| FST | follistatin | -0.00604631 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.00604297 |
| MAP7 | microtubule-associated protein 7 | -0.00604052 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.00602865 |
| HTRA1 | HtrA serine peptidase 1 | -0.00599045 |
| SH3BGRL | SH3 domain binding glutamate-rich protein like | -0.00595172 |
| MAGEF1 | melanoma antigen family F1 | -0.0059425 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.00589308 |
| ZNF580 | zinc finger protein 580 | -0.00589221 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.00586884 |
| ING3 | inhibitor of growth family, member 3 | -0.00584941 |
| RANBP6 | RAN binding protein 6 | -0.00584572 |
| PILRB | paired immunoglobin-like type 2 receptor beta | -0.00583499 |
| CDC7 | cell division cycle 7 | -0.0058195 |
| FGFR3 | fibroblast growth factor receptor 3 | -0.00581262 |
| ITGA7 | integrin, alpha 7 | -0.00580221 |
| PTDSS1 | phosphatidylserine synthase 1 | -0.00579622 |
| MAN2C1 | mannosidase, alpha, class 2C, member 1 | -0.00579133 |
| ATP5ME | ATP synthase membrane subunit e | -0.00578244 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | -0.00577457 |
| ABLIM3 | actin binding LIM protein family, member 3 | -0.00577073 |
| MAP2K7 | mitogen-activated protein kinase kinase 7 | -0.00576428 |
| HOXD1 | homeobox D1 | -0.00575493 |
| SGSM2 | small G protein signaling modulator 2 | -0.00573122 |
| EML3 | echinoderm microtubule associated protein like 3 | -0.00570804 |
| NUP210 | nucleoporin 210kDa | -0.00568871 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -0.00567554 |
| TES | testin LIM domain protein | -0.00566652 |
| BICC1 | BicC family RNA binding protein 1 | -0.00566228 |
| MOK | MOK protein kinase | -0.00565874 |
| GUSB | glucuronidase, beta | -0.00564975 |
| C3ORF14 | chromosome 3 open reading frame 14 | -0.00563642 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -0.00563394 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.00562674 |
| RSBN1 | round spermatid basic protein 1 | -0.00562435 |
| U2AF2 | U2 small nuclear RNA auxiliary factor 2 | -0.00562187 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | -0.0056212 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.0056123 |
| FAM160B2 | family with sequence similarity 160, member B2 | -0.00560857 |
| RANGAP1 | Ran GTPase activating protein 1 | -0.00560702 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | -0.00559544 |
| GUSBP3 | glucuronidase, beta pseudogene 3 | -0.00554476 |
| LOR | loricrin | -0.0055433 |
| TRIB2 | tribbles pseudokinase 2 | -0.00554198 |
| AGTR1 | angiotensin II receptor, type 1 | -0.00554165 |
| CHST1 | carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 | -0.0055307 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | -0.0055275 |
| TARDBP | TAR DNA binding protein | -0.00550395 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | -0.0054957 |
| MCAM | melanoma cell adhesion molecule | -0.00548745 |
| RPS27L | ribosomal protein S27-like | -0.00548683 |
| ABHD6 | abhydrolase domain containing 6 | -0.00548224 |
| NID1 | nidogen 1 | -0.00547686 |
| TAOK1 | TAO kinase 1 | -0.00547439 |
| QPRT | quinolinate phosphoribosyltransferase | -0.00546771 |
| HARS2 | histidyl-tRNA synthetase 2, mitochondrial | -0.00544935 |
| RPA3 | replication protein A3, 14kDa | -0.0054292 |
| LAMP1 | lysosomal-associated membrane protein 1 | -0.00542268 |
| COL9A3 | collagen, type IX, alpha 3 | -0.00542176 |
| TRIM8 | tripartite motif containing 8 | -0.00541728 |
| VPS4B | vacuolar protein sorting 4 homolog B (S. cerevisiae) | -0.00541148 |
| SAFB2 | scaffold attachment factor B2 | -0.00541113 |
| KCNS3 | potassium voltage-gated channel, modifier subfamily S, member 3 | -0.00541088 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides | -0.00541056 |
| BCOR | BCL6 corepressor | -0.0054034 |
| ARHGAP22 | Rho GTPase activating protein 22 | -0.00539979 |
| ZNF83 | zinc finger protein 83 | -0.00539381 |
| ACAA2 | acetyl-CoA acyltransferase 2 | -0.00539239 |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) | -0.00538274 |
| WDTC1 | WD and tetratricopeptide repeats 1 | -0.00537708 |
| JAG2 | jagged 2 | -0.00537311 |
| CRP | C-reactive protein, pentraxin-related | -0.00536857 |
| KDR | kinase insert domain receptor | -0.00536321 |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa | -0.00536284 |
| CA12 | carbonic anhydrase XII | -0.00535135 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | -0.00533861 |
| NEFH | neurofilament, heavy polypeptide | -0.00532031 |
| HELLS | helicase, lymphoid-specific | -0.00531741 |
| DKFZP586I1420 | uncharacterized protein DKFZp586I1420 | -0.00531581 |
| CREBL2 | cAMP responsive element binding protein-like 2 | -0.00530938 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.00530753 |
| DSP | desmoplakin | -0.00530105 |
| TNK2 | tyrosine kinase, non-receptor, 2 | -0.00530082 |
| TSN | translin | -0.00530027 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.00529685 |
| HEXIM1 | hexamethylene bis-acetamide inducible 1 | -0.00529683 |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 | -0.00529471 |
| VPS35L | VPS35 endosomal protein sorting factor like | -0.00529135 |
| EXT1 | exostosin glycosyltransferase 1 | -0.00527903 |
| CUTA | cutA divalent cation tolerance homolog (E. coli) | -0.00527221 |
| LAPTM4A | lysosomal protein transmembrane 4 alpha | -0.00525323 |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit | -0.00521192 |
| ATP13A1 | ATPase type 13A1 | -0.00521044 |
| XYLT1 | xylosyltransferase I | -0.00520018 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | -0.00519524 |
| REEP1 | receptor accessory protein 1 | -0.00519067 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 | -0.00518876 |
| PDGFA | platelet-derived growth factor alpha polypeptide | -0.00517858 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | -0.00515782 |
