MYD88 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description myeloid differentiation primary response 88|This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010] (NCBI Entrez Gene Database, 4615)
External Link https://ncbi.nlm.nih.gov/gene/4615
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Genes

498 genes differentially expressed following the MYD88 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
WDR7 WD repeat domain 7 0.0214324
HSPB8 heat shock 22kDa protein 8 0.0179383
FABP4 fatty acid binding protein 4, adipocyte 0.0176624
IFI27 interferon, alpha-inducible protein 27 0.0173758
CXCL13 chemokine (C-X-C motif) ligand 13 0.0173574
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 0.0160671
COL15A1 collagen, type XV, alpha 1 0.0156281
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.0145289
SLC39A14 solute carrier family 39 (zinc transporter), member 14 0.014412
LUM lumican 0.0134289
ISG15 ISG15 ubiquitin-like modifier 0.0132088
MAGEA3 melanoma antigen family A3 0.0131461
MT1M metallothionein 1M 0.0129409
AMDHD2 amidohydrolase domain containing 2 0.0128278
RGS5 regulator of G-protein signaling 5 0.0126947
CCL19 chemokine (C-C motif) ligand 19 0.012651
MYBPC1 myosin binding protein C, slow type 0.0125389
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 0.0124339
ASPN asporin 0.0124079
RPS4Y1 ribosomal protein S4, Y-linked 1 0.0123979
CLU clusterin 0.0123287
DUSP5 dual specificity phosphatase 5 0.0120709
VWF von Willebrand factor 0.0118442
TNS3 tensin 3 0.0117251
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) 0.0116549
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 0.0116066
APOLD1 apolipoprotein L domain containing 1 0.0111213
COL6A3 collagen, type VI, alpha 3 0.0110313
ADAMDEC1 ADAM-like, decysin 1 0.0109802
PPAP2A phosphatidic acid phosphatase type 2A 0.0109778
C1S complement component 1, s subcomponent 0.0108017
DES desmin 0.0107998
MSX1 msh homeobox 1 0.0107549
SPARCL1 SPARC-like 1 (hevin) 0.0107537
CAV1 caveolin 1, caveolae protein, 22kDa 0.010747
TFF3 trefoil factor 3 (intestinal) 0.0106449
FN1 fibronectin 1 0.0106328
SELE selectin E 0.0105313
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 0.0105246
TSPAN4 tetraspanin 4 0.0103353
COQ8A coenzyme Q8A 0.0103146
KRT17 keratin 17, type I 0.0102548
MAGEA12 melanoma antigen family A12 0.0102468
MTUS1 microtubule associated tumor suppressor 1 0.010209
CCN3 cellular communication network factor 3 0.0101884
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 0.0101173
FBLN1 fibulin 1 0.0100879
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 0.0100608
MYL2 myosin, light chain 2, regulatory, cardiac, slow 0.0100274
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.0100085
TTN titin 0.00997195
COL6A2 collagen, type VI, alpha 2 0.0099564
DYNLL1 dynein, light chain, LC8-type 1 0.00994842
PLXNA1 plexin A1 0.00990266
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 0.00986443
PDE4DIP phosphodiesterase 4D interacting protein 0.00986404
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.00984078
FGFR1 fibroblast growth factor receptor 1 0.00981956
KDSR 3-ketodihydrosphingosine reductase 0.00980432
DIO2 deiodinase, iodothyronine, type II 0.00977256
MIR22HG MIR22 host gene 0.0097313
IGF1 insulin-like growth factor 1 (somatomedin C) 0.00965767
NFE2L1 nuclear factor, erythroid 2-like 1 0.0096573
TNNC1 troponin C type 1 (slow) 0.00957984
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 0.0095373
CD36 CD36 molecule (thrombospondin receptor) 0.00952332
MYOF myoferlin 0.0095108
DPT dermatopontin 0.00947867
ACTA1 actin, alpha 1, skeletal muscle 0.00942511
HSPA1A heat shock 70kDa protein 1A 0.00941174
FMOD fibromodulin 0.00937939
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.0093597
SYNGR3 synaptogyrin 3 0.00931237
FKBP11 FK506 binding protein 11, 19 kDa 0.0092936
TPM2 tropomyosin 2 (beta) 0.00927943
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 0.0092204
CD93 CD93 molecule 0.00921824
MT1G metallothionein 1G 0.00921791
PFKP phosphofructokinase, platelet 0.00920172
MVP major vault protein 0.0091376
MFAP5 microfibrillar associated protein 5 0.0091339
CCL8 chemokine (C-C motif) ligand 8 0.00911202
P2RY14 purinergic receptor P2Y, G-protein coupled, 14 0.00900815
WIF1 WNT inhibitory factor 1 0.00900807
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.00896727
KLHL41 kelch-like family member 41 0.00896129
AOC3 amine oxidase, copper containing 3 0.00888991
HMOX1 heme oxygenase 1 0.0088786
RHOF ras homolog family member F (in filopodia) 0.00887258
RND3 Rho family GTPase 3 0.00886854
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 0.00882319
MAGEA1 melanoma antigen family A1 0.00879485
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 0.00878262
IL32 interleukin 32 0.00870793
L1CAM L1 cell adhesion molecule 0.00869641
CKM creatine kinase, muscle 0.00869005
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 0.00868806
CTSK cathepsin K 0.00868049
SETBP1 SET binding protein 1 0.00864731
NARS1 asparaginyl-tRNA synthetase 1 0.00864511
PARP12 poly (ADP-ribose) polymerase family, member 12 0.00863403
SAMD4A sterile alpha motif domain containing 4A 0.00863358
ADIRF adipogenesis regulatory factor 0.00859156
TNIP1 TNFAIP3 interacting protein 1 0.00857256
TIMP3 TIMP metallopeptidase inhibitor 3 0.00853433
SDC4 syndecan 4 0.00849396
TNNC2 troponin C type 2 (fast) 0.00848871
COL3A1 collagen, type III, alpha 1 0.00847655
ACKR3 atypical chemokine receptor 3 0.00845837
FHL1 four and a half LIM domains 1 0.00845801
RABEP2 rabaptin, RAB GTPase binding effector protein 2 0.00845245
PLXND1 plexin D1 0.00840597
MYL1 myosin, light chain 1, alkali; skeletal, fast 0.00835618
KLF4 Kruppel-like factor 4 (gut) 0.00833205
MYOT myotilin 0.00832713
APOD apolipoprotein D 0.00829849
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae) 0.00829729
MAGEA4 melanoma antigen family A4 0.00825511
FAM50A family with sequence similarity 50, member A 0.0082366
SEC14L1 SEC14-like 1 (S. cerevisiae) 0.00817698
MAST4 microtubule associated serine/threonine kinase family member 4 0.00817642
CFD complement factor D (adipsin) 0.00816256
NR1H3 nuclear receptor subfamily 1, group H, member 3 0.00815779
MAN2A1 mannosidase, alpha, class 2A, member 1 0.00814414
IL6 interleukin 6 0.00814356
AKAP12 A kinase (PRKA) anchor protein 12 0.00813854
TXNL4A thioredoxin-like 4A 0.00812058
NPY1R neuropeptide Y receptor Y1 0.00810891
DMTF1 cyclin D binding myb-like transcription factor 1 0.008107
AMPH amphiphysin 0.00809025
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.0080871
CARD10 caspase recruitment domain family, member 10 0.00807596
COL6A1 collagen, type VI, alpha 1 0.00801567
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 0.00798861
PDLIM5 PDZ and LIM domain 5 0.00798228
PTCH1 patched 1 0.00797874
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 0.00797168
KLF2 Kruppel-like factor 2 0.00797046
WARS1 tryptophanyl-tRNA synthetase 1 0.00793334
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.00792882
ACADVL acyl-CoA dehydrogenase, very long chain 0.00792675
COL5A2 collagen, type V, alpha 2 0.00790918
LYST lysosomal trafficking regulator 0.00789816
MT1H metallothionein 1H 0.00787119
MT2A metallothionein 2A 0.00785123
MYH2 myosin, heavy chain 2, skeletal muscle, adult 0.00780996
CDH5 cadherin 5, type 2 (vascular endothelium) 0.00780903
GLA galactosidase, alpha 0.00779294
PCSK5 proprotein convertase subtilisin/kexin type 5 0.00776724
IRS1 insulin receptor substrate 1 0.00776212
MFAP4 microfibrillar-associated protein 4 0.00775629
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.00774303
AKAP9 A kinase (PRKA) anchor protein 9 0.00774172
OLFML2B olfactomedin-like 2B 0.00767794
THBS4 thrombospondin 4 0.00766243
PCOLCE procollagen C-endopeptidase enhancer 0.00762494
PDGFRL platelet-derived growth factor receptor-like 0.00761323
DST dystonin 0.00759077
FZD10 frizzled class receptor 10 0.00759047
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related) 0.00758839
INA internexin neuronal intermediate filament protein, alpha 0.00757856
AKAP8 A kinase (PRKA) anchor protein 8 0.00757687
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 0.0075727
MBD1 methyl-CpG binding domain protein 1 0.00754074
TGM2 transglutaminase 2 0.00753514
ADRB2 adrenoceptor beta 2, surface 0.00752969
MITF microphthalmia-associated transcription factor 0.00750783
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase 0.00748949
ADIPOQ adiponectin, C1Q and collagen domain containing 0.00747901
GULP1 GULP, engulfment adaptor PTB domain containing 1 0.00745057
SIGLEC15 sialic acid binding Ig-like lectin 15 0.00744694
CLEC3B C-type lectin domain family 3, member B 0.0073997
ZBTB35 zinc finger and BTB domain containing 35 0.0073905
CRIP1 cysteine-rich protein 1 (intestinal) 0.00737666
LAMB2 laminin, beta 2 (laminin S) 0.0073515
FLT1 fms-related tyrosine kinase 1 0.00734603
EZR ezrin 0.0073319
NNMT nicotinamide N-methyltransferase 0.00732228
CXCR4 chemokine (C-X-C motif) receptor 4 0.00731901
DMD dystrophin 0.0073107
PLVAP plasmalemma vesicle associated protein 0.00730233
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 0.00729388
PLA2G2D phospholipase A2, group IID 0.0072892
GCH1 GTP cyclohydrolase 1 0.00728698
CADM1 cell adhesion molecule 1 0.00727547
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene) 0.00727309
MPDZ multiple PDZ domain protein 0.00726921
WFDC1 WAP four-disulfide core domain 1 0.00722666
HSPH1 heat shock 105kDa/110kDa protein 1 0.00720029
TCTA T-cell leukemia translocation altered 0.00716174
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 0.00716009
DSP desmoplakin 0.00715906
PPL periplakin 0.00715547
TGFB3 transforming growth factor, beta 3 0.00714056
MORC2 MORC family CW-type zinc finger 2 0.00711771
PKD1P1 polycystic kidney disease 1 (autosomal dominant) pseudogene 1 0.00709466
STC2 stanniocalcin 2 0.0070936
HSPG2 heparan sulfate proteoglycan 2 0.00707492
DCN decorin 0.00706468
UBR4 ubiquitin protein ligase E3 component n-recognin 4 0.00706398
JAG1 jagged 1 0.00705389
C14ORF132 chromosome 14 open reading frame 132 0.00705384
PTPRM protein tyrosine phosphatase, receptor type, M 0.00705199
LOXL2 lysyl oxidase-like 2 0.00704281
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 0.00704004
ZCCHC2 zinc finger, CCHC domain containing 2 0.00703733
PMP22 peripheral myelin protein 22 0.00703018
LDB2 LIM domain binding 2 0.00702508
PRAME preferentially expressed antigen in melanoma 0.00702027
SV2B synaptic vesicle glycoprotein 2B 0.00701132
GMDS GDP-mannose 4,6-dehydratase 0.00699246
FHL2 four and a half LIM domains 2 0.00698404
SQSTM1 sequestosome 1 0.0069473
SNAI2 snail family zinc finger 2 0.00691456
EGFL6 EGF-like-domain, multiple 6 0.00691212
EPB41L3 erythrocyte membrane protein band 4.1-like 3 0.00690921
CTSA cathepsin A 0.00689855
PERP PERP, TP53 apoptosis effector 0.00688319
COL7A1 collagen, type VII, alpha 1 0.00687812
CHGB chromogranin B 0.00687712
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 0.00686783
DAAM2 dishevelled associated activator of morphogenesis 2 0.00684372
MT1F metallothionein 1F 0.00684017
FYCO1 FYVE and coiled-coil domain containing 1 0.00682417
MT1X metallothionein 1X 0.00680842
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.00678711
MTCL1 microtubule crosslinking factor 1 0.00678566
CALML5 calmodulin-like 5 0.00677853
DOCK9 dedicator of cytokinesis 9 0.00677779
CASQ2 calsequestrin 2 (cardiac muscle) 0.00676866
EHD3 EH-domain containing 3 0.0067579
FBN1 fibrillin 1 0.00675713
SLC39A6 solute carrier family 39 (zinc transporter), member 6 0.00675157
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa 0.00674611
GOLGA8A golgin A8 family, member A 0.00673022
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 0.00671611
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase 0.00669561
SASH1 SAM and SH3 domain containing 1 0.00667805
ACTN2 actinin, alpha 2 0.00666755
CCT3 chaperonin containing TCP1, subunit 3 (gamma) 0.00666277
TNNI2 troponin I type 2 (skeletal, fast) 0.00664454
BCAP31 B-cell receptor-associated protein 31 0.00662707
TPM3 tropomyosin 3 0.00660748
IDO1 indoleamine 2,3-dioxygenase 1 0.00660376
RAMP3 receptor (G protein-coupled) activity modifying protein 3 0.00657624
TSPAN7 tetraspanin 7 0.00657438
DGLUCY D-glutamate cyclase 0.0065526
CHGA chromogranin A 0.00655037
LPCAT1 lysophosphatidylcholine acyltransferase 1 0.00654874

decreased expression

Symbol Name Standardized Value
SSBP2 single-stranded DNA binding protein 2 -0.0393603
LCN2 lipocalin 2 -0.0191031
ALOX5 arachidonate 5-lipoxygenase -0.0158695
SORL1 sortilin-related receptor, L(DLR class) A repeats containing -0.014172
AUTS2 autism susceptibility candidate 2 -0.0141063
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.0140957
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 -0.0132898
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) -0.0131049
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -0.0126037
KIAA0226L KIAA0226-like -0.0124191
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 -0.0123102
ENC1 ectodermal-neural cortex 1 (with BTB domain) -0.0122701
OLFM4 olfactomedin 4 -0.0120112
ZFP36L1 ZFP36 ring finger protein-like 1 -0.0119005
IGFBP2 insulin-like growth factor binding protein 2, 36kDa -0.011822
PDZK1IP1 PDZK1 interacting protein 1 -0.0117189
GCA grancalcin, EF-hand calcium binding protein -0.0116766
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) -0.0114778
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) -0.0114583
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 -0.0113974
VTCN1 V-set domain containing T cell activation inhibitor 1 -0.0113786
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 -0.0113185
WT1 Wilms tumor 1 -0.0112061
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 -0.0110475
S100A8 S100 calcium binding protein A8 -0.0110316
IGLL1 immunoglobulin lambda-like polypeptide 1 -0.011007
PCP4 Purkinje cell protein 4 -0.0109879
ZDHHC6 zinc finger, DHHC-type containing 6 -0.01096
WFDC2 WAP four-disulfide core domain 2 -0.010777
TACSTD2 tumor-associated calcium signal transducer 2 -0.0107044
ARID4A AT rich interactive domain 4A (RBP1-like) -0.010627
GNG7 guanine nucleotide binding protein (G protein), gamma 7 -0.0106161
FLRT3 fibronectin leucine rich transmembrane protein 3 -0.0105727
CA12 carbonic anhydrase XII -0.0105688
DPYD dihydropyrimidine dehydrogenase -0.0105328
HBB hemoglobin, beta -0.0104671
LPAR6 lysophosphatidic acid receptor 6 -0.0104598
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) -0.0103772
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta -0.010278
MZB1 marginal zone B and B1 cell-specific protein -0.0102121
CFI complement factor I -0.010135
CD300A CD300a molecule -0.0101068
CLC Charcot-Leyden crystal galectin -0.00996962
METRN meteorin, glial cell differentiation regulator -0.00993232
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) -0.00992372
FOLR1 folate receptor 1 (adult) -0.00988666
ADD3 adducin 3 (gamma) -0.00986736
ALB albumin -0.00981024
CXCL8 chemokine (C-X-C motif) ligand 8 -0.00977686
AOC1 amine oxidase, copper containing 1 -0.00976956
KRT19 keratin 19, type I -0.00975472
DPEP1 dipeptidase 1 (renal) -0.00975132
SCG5 secretogranin V -0.00970685
NREP neuronal regeneration related protein -0.00968844
TSPAN5 tetraspanin 5 -0.00956941
CRABP2 cellular retinoic acid binding protein 2 -0.00955787
C3ORF14 chromosome 3 open reading frame 14 -0.00952833
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial -0.00952217
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta -0.0095127
RNASE6 ribonuclease, RNase A family, k6 -0.00949063
CDH3 cadherin 3, type 1, P-cadherin (placental) -0.00942203
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 -0.00937878
LAPTM5 lysosomal protein transmembrane 5 -0.0093316
SNCA synuclein, alpha (non A4 component of amyloid precursor) -0.00927654
DCK deoxycytidine kinase -0.00923936
DACH1 dachshund family transcription factor 1 -0.00923745
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) -0.00921486
KCTD12 potassium channel tetramerization domain containing 12 -0.00921251
TCL1A T-cell leukemia/lymphoma 1A -0.00921093
KLHDC8A kelch domain containing 8A -0.00919824
DEFB1 defensin, beta 1 -0.00919756
CEMIP cell migration inducing protein, hyaluronan binding -0.00919417
PCDH9 protocadherin 9 -0.00917209
HP haptoglobin -0.00908361
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 -0.0090188
MYB v-myb avian myeloblastosis viral oncogene homolog -0.00897641
FCN1 ficolin (collagen/fibrinogen domain containing) 1 -0.00891359
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) -0.00888306
S100A9 S100 calcium binding protein A9 -0.00882864
MSMO1 methylsterol monooxygenase 1 -0.00882304
BPI bactericidal/permeability-increasing protein -0.00875117
SLC2A4RG SLC2A4 regulator -0.00874934
GFAP glial fibrillary acidic protein -0.00870868
LST1 leukocyte specific transcript 1 -0.00870286
DUOX2 dual oxidase 2 -0.00866403
PHACTR1 phosphatase and actin regulator 1 -0.00861207
PECR peroxisomal trans-2-enoyl-CoA reductase -0.00856089
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide -0.00850871
MGAM maltase-glucoamylase -0.00850144
LDOC1 leucine zipper, down-regulated in cancer 1 -0.00848394
FPR1 formyl peptide receptor 1 -0.00847391
PF4 platelet factor 4 -0.0084542
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 -0.00843491
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) -0.00838392
SC5D sterol-C5-desaturase -0.0083748
SPTSSA serine palmitoyltransferase, small subunit A -0.0083733
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) -0.00836023
MAL mal, T-cell differentiation protein -0.00834162
NUSAP1 nucleolar and spindle associated protein 1 -0.00833922
CLEC5A C-type lectin domain family 5, member A -0.00832373
CDCA4 cell division cycle associated 4 -0.00830679
HTRA1 HtrA serine peptidase 1 -0.00826074
INSIG1 insulin induced gene 1 -0.0081647
CD9 CD9 molecule -0.00815726
KLK7 kallikrein-related peptidase 7 -0.0080818
STK38L serine/threonine kinase 38 like -0.00805843
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein -0.00804701
IL2RG interleukin 2 receptor, gamma -0.00801801
NPM3 nucleophosmin/nucleoplasmin 3 -0.00799421
PAN2 PAN2 poly(A) specific ribonuclease subunit -0.00798737
S100A12 S100 calcium binding protein A12 -0.00798006
OXA1L oxidase (cytochrome c) assembly 1-like -0.00795207
HMGN4 high mobility group nucleosomal binding domain 4 -0.00794966
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 -0.00789968
CASP1 caspase 1, apoptosis-related cysteine peptidase -0.00789739
FAM171A1 family with sequence similarity 171, member A1 -0.00788874
ALOX5AP arachidonate 5-lipoxygenase-activating protein -0.00785032
SGMS1 sphingomyelin synthase 1 -0.00784278
KRT23 keratin 23, type I -0.0078378
ARMCX2 armadillo repeat containing, X-linked 2 -0.00780277
ZNF22 zinc finger protein 22 -0.00779928
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 -0.00778145
SIRT3 sirtuin 3 -0.00777616
XIC X chromosome inactivation center -0.00775926
CASP10 caspase 10, apoptosis-related cysteine peptidase -0.00773077
LTA4H leukotriene A4 hydrolase -0.00768555
DIRAS3 DIRAS family, GTP-binding RAS-like 3 -0.00768444
GPM6A glycoprotein M6A -0.0076773
KRCC1 lysine-rich coiled-coil 1 -0.00766524
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) -0.00765478
CSTA cystatin A (stefin A) -0.00763174
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 -0.0076142
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -0.00761131
LGALS13 lectin, galactoside-binding, soluble, 13 -0.00756319
IRX5 iroquois homeobox 5 -0.00754578
ACSM3 acyl-CoA synthetase medium-chain family member 3 -0.00752555
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.00750484
CETN2 centrin, EF-hand protein, 2 -0.00747197
DNTT DNA nucleotidylexotransferase -0.00744094
PDZD8 PDZ domain containing 8 -0.00742414
FJX1 four jointed box 1 (Drosophila) -0.00740418
SLPI secretory leukocyte peptidase inhibitor -0.0073982
RAD21 RAD21 homolog (S. pombe) -0.00739768
NPC2 Niemann-Pick disease, type C2 -0.00738673
RBM3 RNA binding motif (RNP1, RRM) protein 3 -0.00736743
SMYD3 SET and MYND domain containing 3 -0.00736488
BLNK B-cell linker -0.0073647
RNF5 ring finger protein 5, E3 ubiquitin protein ligase -0.00735224
EIF3M eukaryotic translation initiation factor 3, subunit M -0.00731796
PLBD1 phospholipase B domain containing 1 -0.00731647
TREM2 triggering receptor expressed on myeloid cells 2 -0.00731528
FOXC1 forkhead box C1 -0.0073112
TMEM45A transmembrane protein 45A -0.0073024
ANPEP alanyl (membrane) aminopeptidase -0.00729145
EFHC2 EF-hand domain (C-terminal) containing 2 -0.00721417
ZBTB18 zinc finger and BTB domain containing 18 -0.00721307
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1 -0.00720797
CORO2B coronin, actin binding protein, 2B -0.00719102
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 -0.00717347
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 -0.00716722
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 -0.00715618
LYN LYN proto-oncogene, Src family tyrosine kinase -0.00715251
CKAP2 cytoskeleton associated protein 2 -0.00713345
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 -0.00712476
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.00711988
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit -0.00710353
ZNF274 zinc finger protein 274 -0.00710188
PTMS parathymosin -0.00709164
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -0.00709095
VAV3 vav 3 guanine nucleotide exchange factor -0.00709086
IFITM2 interferon induced transmembrane protein 2 -0.00708426
ACOX2 acyl-CoA oxidase 2, branched chain -0.00708136
TGFBI transforming growth factor, beta-induced, 68kDa -0.00706863
GAP43 growth associated protein 43 -0.00705644
PBX3 pre-B-cell leukemia homeobox 3 -0.00705599
TRMT5 tRNA methyltransferase 5 -0.00705289
SELL selectin L -0.00704513
TCF21 transcription factor 21 -0.00703441
CENPU centromere protein U -0.00702676
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein -0.00701985
PTPRD protein tyrosine phosphatase, receptor type, D -0.00701533
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) -0.00699201
ACAT2 acetyl-CoA acetyltransferase 2 -0.00698857
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 -0.00698044
CCNA2 cyclin A2 -0.00697454
CHPT1 choline phosphotransferase 1 -0.00696038
PUF60 poly-U binding splicing factor 60KDa -0.00695954
HBD hemoglobin, delta -0.00694364
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor -0.00694201
PRKCA protein kinase C, alpha -0.00692756
CYP4F3 cytochrome P450, family 4, subfamily F, polypeptide 3 -0.00690601
EVI2A ecotropic viral integration site 2A -0.00689451
FAR2 fatty acyl CoA reductase 2 -0.00688361
SLC16A4 solute carrier family 16, member 4 -0.00688291
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 -0.00687816
RAG1 recombination activating gene 1 -0.00686832
CD1E CD1e molecule -0.00685802
C12ORF29 chromosome 12 open reading frame 29 -0.00681299
TESC tescalcin -0.00677205
ALDOB aldolase B, fructose-bisphosphate -0.00675836
TEX30 testis expressed 30 -0.00674331
NPTX2 neuronal pentraxin II -0.00671125
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) -0.00670159
PRDX2 peroxiredoxin 2 -0.00663207
FAM107A family with sequence similarity 107, member A -0.00661747
GPR183 G protein-coupled receptor 183 -0.00661302
KLK6 kallikrein-related peptidase 6 -0.00658479
WASHC4 WASH complex subunit 4 -0.00658382
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) -0.006567
LTF lactotransferrin -0.00656244
MBOAT2 membrane bound O-acyltransferase domain containing 2 -0.00656241
SQLE squalene epoxidase -0.00656241
ENDOD1 endonuclease domain containing 1 -0.006559
DEFA4 defensin, alpha 4, corticostatin -0.00655775
HMGB3 high mobility group box 3 -0.00655307
APOC1 apolipoprotein C-I -0.00655079
ELOVL2 ELOVL fatty acid elongase 2 -0.00655001
NRGN neurogranin (protein kinase C substrate, RC3) -0.00653557
GLIPR1 GLI pathogenesis-related 1 -0.0065329
PEG10 paternally expressed 10 -0.00652767
ASGR2 asialoglycoprotein receptor 2 -0.00651777
MARCKSL1 MARCKS-like 1 -0.00650212
VCAN versican -0.00649928
MNDA myeloid cell nuclear differentiation antigen -0.00649747
NME5 NME/NM23 family member 5 -0.00649645
TPM4 tropomyosin 4 -0.00648227
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -0.00648118
PNMA8A PNMA family member 8A -0.00648097
MCUB mitochondrial calcium uniporter dominant negative subunit beta -0.0064784
TYROBP TYRO protein tyrosine kinase binding protein -0.00646509
DHFR dihydrofolate reductase -0.00646435
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 -0.00646427
SPIN1 spindlin 1 -0.00646196
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 -0.00644677
PPA2 pyrophosphatase (inorganic) 2 -0.0064462
MSLN mesothelin -0.00643264
MMP8 matrix metallopeptidase 8 -0.00643015
ANXA3 annexin A3 -0.00642248
FHIT fragile histidine triad -0.00641969
ARF4 ADP-ribosylation factor 4 -0.00641306
BPHL biphenyl hydrolase-like (serine hydrolase) -0.006413
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) -0.00641132
IDI1 isopentenyl-diphosphate delta isomerase 1 -0.00641122
ALDH3B2 aldehyde dehydrogenase 3 family, member B2 -0.00640986
DPY19L2P2 DPY19L2 pseudogene 2 -0.00640557
BUB3 BUB3 mitotic checkpoint protein -0.00640323
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) -0.00639621
MAPK14 mitogen-activated protein kinase 14 -0.00638306
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 -0.00637822