MYH7 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description myosin, heavy chain 7, cardiac muscle, beta|Muscle myosin is a hexameric protein containing 2 heavy chain subunits, 2 alkali light chain subunits, and 2 regulatory light chain subunits. This gene encodes the beta (or slow) heavy chain subunit of cardiac myosin. It is expressed predominantly in normal human ventricle. It is also expressed in skeletal muscle tissues rich in slow-twitch type I muscle fibers. Changes in the relative abundance of this protein and the alpha (or fast) heavy subunit of cardiac myosin correlate with the contractile velocity of cardiac muscle. Its expression is also altered during thyroid hormone depletion and hemodynamic overloading. Mutations in this gene are associated with familial hypertrophic cardiomyopathy, myosin storage myopathy, dilated cardiomyopathy, and Laing early-onset distal myopathy. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 4625)
External Link http://www.ncbi.nlm.nih.gov/gene/4625
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221 interacting proteins for MYH7 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ACSM2B acyl-CoA synthetase medium-chain family member 2B
ACTA1 actin, alpha 1, skeletal muscle
ACTA2 actin, alpha 2, smooth muscle, aorta
ACTB actin, beta
ACTBL2 actin, beta-like 2
ACTC1 actin, alpha, cardiac muscle 1
ACTG1 actin gamma 1
ACTG2 actin, gamma 2, smooth muscle, enteric
ACTN2 actinin, alpha 2
ACTN3 actinin, alpha 3 (gene/pseudogene)
AKAP8 A kinase (PRKA) anchor protein 8
ANKRD18A ankyrin repeat domain 18A
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
BAIAP2L1 BAI1-associated protein 2-like 1
BANK1 B-cell scaffold protein with ankyrin repeats 1
BAZ1A bromodomain adjacent to zinc finger domain, 1A
BCLAF1 BCL2-associated transcription factor 1
C19ORF68 chromosome 19 open reading frame 68
C9ORF114 chromosome 9 open reading frame 114
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CEP250 centrosomal protein 250kDa
CGN cingulin
CNTRL centriolin
COIL coilin
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CPT1A carnitine palmitoyltransferase 1A (liver)
CSE1L CSE1 chromosome segregation 1-like (yeast)
CWC15 CWC15 spliceosome-associated protein
DBN1 drebrin 1
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
DES desmin
DISC1 disrupted in schizophrenia 1
DOK6 docking protein 6
EEF1A1 eukaryotic translation elongation factor 1 alpha 1
EFTUD2 elongation factor Tu GTP binding domain containing 2
EIF2A eukaryotic translation initiation factor 2A, 65kDa
ELMSAN1 ELM2 and Myb/SANT-like domain containing 1
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
EXOC1 exocyst complex component 1
EXOC2 exocyst complex component 2
EXOC3 exocyst complex component 3
EXOC4 exocyst complex component 4
EXOC5 exocyst complex component 5
EXOC6 exocyst complex component 6
EXOC7 exocyst complex component 7
EXOC8 exocyst complex component 8
EXOSC10 exosome component 10
EXOSC4 exosome component 4
FMR1 fragile X mental retardation 1
FTSJ3 FtsJ homolog 3 (E. coli)
FXR2 fragile X mental retardation, autosomal homolog 2
GCC2 GRIP and coiled-coil domain containing 2
GNL3 guanine nucleotide binding protein-like 3 (nucleolar)
GSN gelsolin
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa
GTF3C3 general transcription factor IIIC, polypeptide 3, 102kDa
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
H1F0 H1 histone family, member 0
H2AFX H2A histone family, member X
H2BFS H2B histone family, member S (pseudogene)
HIST1H1C histone cluster 1, H1c
HIST1H1D histone cluster 1, H1d
HIST1H1T histone cluster 1, H1t
HIST1H2AI histone cluster 1, H2ai
HIST1H2BD histone cluster 1, H2bd
HIST1H4F histone cluster 1, H4f
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2)
HNRNPCL1 heterogeneous nuclear ribonucleoprotein C-like 1
HNRNPH2 heterogeneous nuclear ribonucleoprotein H2 (H')
HSPA1B heat shock 70kDa protein 1B
HSPA8 heat shock 70kDa protein 8
HSPB1 heat shock 27kDa protein 1
KANK2 KN motif and ankyrin repeat domains 2
KIAA0368 KIAA0368
KRT17 keratin 17, type I
KRT18 keratin 18, type I
KRT8 keratin 8, type II
LACTB lactamase, beta
LAMB1 laminin, beta 1
LAS1L LAS1-like (S. cerevisiae)
LIMA1 LIM domain and actin binding 1
LMNA lamin A/C
LRRC59 leucine rich repeat containing 59
MED1 mediator complex subunit 1
MED17 mediator complex subunit 17
MED4 mediator complex subunit 4
MKI67 marker of proliferation Ki-67
MLLT1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1
MRPS15 mitochondrial ribosomal protein S15
MRPS22 mitochondrial ribosomal protein S22
MYBBP1A MYB binding protein (P160) 1a
MYH11 myosin, heavy chain 11, smooth muscle
MYH13 myosin, heavy chain 13, skeletal muscle
MYH14 myosin, heavy chain 14, non-muscle
MYH2 myosin, heavy chain 2, skeletal muscle, adult
MYH3 myosin, heavy chain 3, skeletal muscle, embryonic
MYH4 myosin, heavy chain 4, skeletal muscle
MYH7B myosin, heavy chain 7B, cardiac muscle, beta
MYH9 myosin, heavy chain 9, non-muscle
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle
MYLK myosin light chain kinase
MYLK2 myosin light chain kinase 2
MYLK3 myosin light chain kinase 3
MYO1C myosin IC
MYO1D myosin ID
MYOM2 myomesin 2
NAT10 N-acetyltransferase 10 (GCN5-related)
NCOA3 nuclear receptor coactivator 3
NEBL nebulette
NEFH neurofilament, heavy polypeptide
NKRF NFKB repressing factor
NOLC1 nucleolar and coiled-body phosphoprotein 1
NOP56 NOP56 ribonucleoprotein
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NRIP1 nuclear receptor interacting protein 1
NTHL1 nth endonuclease III-like 1 (E. coli)
PELP1 proline, glutamate and leucine rich protein 1
PIP prolactin-induced protein
PKP3 plakophilin 3
POLR1E polymerase (RNA) I polypeptide E, 53kDa
POM121 POM121 transmembrane nucleoporin
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
PTCD3 pentatricopeptide repeat domain 3
PTPN23 protein tyrosine phosphatase, non-receptor type 23
PURA purine-rich element binding protein A
PURB purine-rich element binding protein B
PWP1 PWP1 homolog (S. cerevisiae)
RALA v-ral simian leukemia viral oncogene homolog A (ras related)
RALY RALY heterogeneous nuclear ribonucleoprotein
RBM10 RNA binding motif protein 10
RBM14 RNA binding motif protein 14
RBM28 RNA binding motif protein 28
RFC1 replication factor C (activator 1) 1, 145kDa
RFC2 replication factor C (activator 1) 2, 40kDa
RFC4 replication factor C (activator 1) 4, 37kDa
RIMS2 regulating synaptic membrane exocytosis 2
RNF167 ring finger protein 167
RPL10A ribosomal protein L10a
RPL17 ribosomal protein L17
RPL18A ribosomal protein L18a
RPL23 ribosomal protein L23
RPL29 ribosomal protein L29
RPL36AL ribosomal protein L36a-like
RPL7 ribosomal protein L7
RPL7A ribosomal protein L7a
RPLP0 ribosomal protein, large, P0
RPS11 ribosomal protein S11
RPS13 ribosomal protein S13
RPS16 ribosomal protein S16
RPS17 ribosomal protein S17
RPS18 ribosomal protein S18
RPS25 ribosomal protein S25
RPS26 ribosomal protein S26
RPS27L ribosomal protein S27-like
RPS3 ribosomal protein S3
RPS4X ribosomal protein S4, X-linked
RPS9 ribosomal protein S9
RRP1 ribosomal RNA processing 1
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
RRP1B ribosomal RNA processing 1B
SEMG2 semenogelin II
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3
SFN stratifin
SHROOM3 shroom family member 3
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
SMN2 survival of motor neuron 2, centromeric
SNAPIN SNAP-associated protein
SPTBN2 spectrin, beta, non-erythrocytic 2
SRRM2 serine/arginine repetitive matrix 2
STAU1 staufen double-stranded RNA binding protein 1
STK31 serine/threonine kinase 31
SURF6 surfeit 6
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TEAD3 TEA domain family member 3
TEAD4 TEA domain family member 4
TGIF2LY TGFB-induced factor homeobox 2-like, Y-linked
TPM1 tropomyosin 1 (alpha)
TSC2 tuberous sclerosis 2
TTC21B tetratricopeptide repeat domain 21B
TTN titin
TUBA1C tubulin, alpha 1c
TUBB2A tubulin, beta 2A class IIa
TULP3 tubby like protein 3
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBC ubiquitin C
UBN1 ubinuclein 1
UBR3 ubiquitin protein ligase E3 component n-recognin 3 (putative)
USP42 ubiquitin specific peptidase 42
VASP vasodilator-stimulated phosphoprotein
VIM vimentin
VMAC vimentin-type intermediate filament associated coiled-coil protein
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae)
WDR18 WD repeat domain 18
WNK4 WNK lysine deficient protein kinase 4
WWOX WW domain containing oxidoreductase
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZC3H18 zinc finger CCCH-type containing 18
ZC3HAV1 zinc finger CCCH-type, antiviral 1
ZFP91 ZFP91 zinc finger protein
ZFR zinc finger RNA binding protein
ZNF512B zinc finger protein 512B
ZNF638 zinc finger protein 638