MYOC Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description myocilin, trabecular meshwork inducible glucocorticoid response|MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 4653)
External Link http://www.ncbi.nlm.nih.gov/gene/4653
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Genes

44 interacting proteins for MYOC from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
A2M alpha-2-macroglobulin
ACTA2 actin, alpha 2, smooth muscle, aorta
ACTB actin, beta
ACTG1 actin gamma 1
ALDOA aldolase A, fructose-bisphosphate
ANXA2 annexin A2
C1QB complement component 1, q subcomponent, B chain
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast)
CD81 CD81 molecule
CKM creatine kinase, muscle
CLIC1 chloride intracellular channel 1
COL1A2 collagen, type I, alpha 2
COL3A1 collagen, type III, alpha 1
ECE1 endothelin converting enzyme 1
EEF1A1 eukaryotic translation elongation factor 1 alpha 1
ENO1 enolase 1, (alpha)
FBN1 fibrillin 1
FN1 fibronectin 1
FTL ferritin, light polypeptide
FUBP1 far upstream element (FUSE) binding protein 1
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GGTLC1 gamma-glutamyltransferase light chain 1
HAGH hydroxyacylglutathione hydrolase
HSPA4 heat shock 70kDa protein 4
IGLL1 immunoglobulin lambda-like polypeptide 1
ITGA7 integrin, alpha 7
LAMA5 laminin, alpha 5
LGALS3 lectin, galactoside-binding, soluble, 3
MAEA macrophage erythroblast attacher
MYH11 myosin, heavy chain 11, smooth muscle
MYL2 myosin, light chain 2, regulatory, cardiac, slow
NOTCH2 notch 2
OLFM3 olfactomedin 3
OLFML3 olfactomedin-like 3
PKLR pyruvate kinase, liver and RBC
PKM pyruvate kinase, muscle
RFC1 replication factor C (activator 1) 1, 145kDa
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
TGFBR1 transforming growth factor, beta receptor 1
TIMP1 TIMP metallopeptidase inhibitor 1
TKT transketolase
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TPM1 tropomyosin 1 (alpha)
VIM vimentin