MZ1-PC Gene Set

Dataset COSMIC Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description cell line derived from pancreas (Catalogue of Somatic Mutations In Cancer)
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Genes

266 genes mutated in the MZ1-PC cell line from the COSMIC Cell Line Gene Mutation Profiles dataset.

Symbol Name
A1CF APOBEC1 complementation factor
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5
ABRA actin binding Rho activating protein
ACSM5 acyl-CoA synthetase medium-chain family member 5
ADA adenosine deaminase
ADAD2 adenosine deaminase domain containing 2
ADAM29 ADAM metallopeptidase domain 29
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2
ADAMTSL4 ADAMTS-like 4
ADCY5 adenylate cyclase 5
ADGRL2 adhesion G protein-coupled receptor L2
AKAP12 A kinase (PRKA) anchor protein 12
ANKRD24 ankyrin repeat domain 24
ANKRD26 ankyrin repeat domain 26
ANO1 anoctamin 1, calcium activated chloride channel
ANXA9 annexin A9
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3
ARHGAP20 Rho GTPase activating protein 20
ARPP21 cAMP-regulated phosphoprotein, 21kDa
AS3MT arsenite methyltransferase
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
BCHE butyrylcholinesterase
BIRC6 baculoviral IAP repeat containing 6
BRPF3 bromodomain and PHD finger containing, 3
BTD biotinidase
BTNL3 butyrophilin-like 3
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit
CASP10 caspase 10, apoptosis-related cysteine peptidase
CC2D2A coiled-coil and C2 domain containing 2A
CCND1 cyclin D1
CD44 CD44 molecule (Indian blood group)
CD58 CD58 molecule
CDH23 cadherin-related 23
CDKN2A cyclin-dependent kinase inhibitor 2A
CEP250 centrosomal protein 250kDa
CFLAR CASP8 and FADD-like apoptosis regulator
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
CIITA class II, major histocompatibility complex, transactivator
CNOT1 CCR4-NOT transcription complex, subunit 1
CNOT10 CCR4-NOT transcription complex, subunit 10
CNTNAP1 contactin associated protein 1
CPA4 carboxypeptidase A4
CPNE8 copine VIII
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CYFIP2 cytoplasmic FMR1 interacting protein 2
CYLC2 cylicin, basic protein of sperm head cytoskeleton 2
DCTN5 dynactin 5 (p25)
DEPDC5 DEP domain containing 5
DIRC1 disrupted in renal carcinoma 1
DOCK10 dedicator of cytokinesis 10
DOCK5 dedicator of cytokinesis 5
DSCAML1 Down syndrome cell adhesion molecule like 1
DTX2 deltex 2, E3 ubiquitin ligase
EBF1 early B-cell factor 1
EDN3 endothelin 3
EFCAB3 EF-hand calcium binding domain 3
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EIF3H eukaryotic translation initiation factor 3, subunit H
ELFN2 extracellular leucine-rich repeat and fibronectin type III domain containing 2
EPC1 enhancer of polycomb homolog 1 (Drosophila)
EPHB3 EPH receptor B3
FAF1 Fas (TNFRSF6) associated factor 1
FAM136A family with sequence similarity 136, member A
FAM196A family with sequence similarity 196, member A
FAM19A3 family with sequence similarity 19 (chemokine (C-C motif)-like), member A3
FAM90A20P putative protein FAM90A20
FBXO30 F-box protein 30
FBXW2 F-box and WD repeat domain containing 2
FCRL3 Fc receptor-like 3
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FOXA3 forkhead box A3
FOXJ1 forkhead box J1
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FPGT fucose-1-phosphate guanylyltransferase
FRMPD1 FERM and PDZ domain containing 1
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
GCN1L1 GCN1 general control of amino-acid synthesis 1-like 1 (yeast)
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1
HNRNPM heterogeneous nuclear ribonucleoprotein M
HRASLS5 HRAS-like suppressor family, member 5
HRH2 histamine receptor H2
HS2ST1 heparan sulfate 2-O-sulfotransferase 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HTR3D 5-hydroxytryptamine (serotonin) receptor 3D, ionotropic
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
IFT54 intraflagellar transport 54
IFT57 intraflagellar transport 57
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1
IGSF9B immunoglobulin superfamily, member 9B
INO80B INO80 complex subunit B
INSIG1 insulin induced gene 1
INTU inturned planar cell polarity protein
JARID2 jumonji, AT rich interactive domain 2
KANK1 KN motif and ankyrin repeat domains 1
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3
KCTD3 potassium channel tetramerization domain containing 3
KIF5C kinesin family member 5C
KLF17 Kruppel-like factor 17
KLRC1 killer cell lectin-like receptor subfamily C, member 1
KMT2A lysine (K)-specific methyltransferase 2A
KMT2D lysine (K)-specific methyltransferase 2D
KRAS Kirsten rat sarcoma viral oncogene homolog
KRTAP5-2 keratin associated protein 5-2
LAMA1 laminin, alpha 1
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
LIMS2 LIM and senescent cell antigen-like domains 2
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LRP1B low density lipoprotein receptor-related protein 1B
LRP2 low density lipoprotein receptor-related protein 2
LRRTM3 leucine rich repeat transmembrane neuronal 3
MAGEB6 melanoma antigen family B6
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MARCH7 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase
MBD5 methyl-CpG binding domain protein 5
MDN1 MDN1, midasin homolog (yeast)
MEIS2 Meis homeobox 2
MESP1 mesoderm posterior basic helix-loop-helix transcription factor 1
MIS18BP1 MIS18 binding protein 1
MOG myelin oligodendrocyte glycoprotein
MTMR7 myotubularin related protein 7
MTPN myotrophin
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase
MYH14 myosin, heavy chain 14, non-muscle
NCKAP5 NCK-associated protein 5
NEB nebulin
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFE2L3 nuclear factor, erythroid 2-like 3
NLRP7 NLR family, pyrin domain containing 7
NLRP9 NLR family, pyrin domain containing 9
NOD2 nucleotide-binding oligomerization domain containing 2
NR1H4 nuclear receptor subfamily 1, group H, member 4
NR2C2AP nuclear receptor 2C2-associated protein
NR2F6 nuclear receptor subfamily 2, group F, member 6
NT5C2 5'-nucleotidase, cytosolic II
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OR1M1 olfactory receptor, family 1, subfamily M, member 1
OR2C1 olfactory receptor, family 2, subfamily C, member 1
OR2L2 olfactory receptor, family 2, subfamily L, member 2
OR2T27 olfactory receptor, family 2, subfamily T, member 27
OR4A15 olfactory receptor, family 4, subfamily A, member 15
OR4S1 olfactory receptor, family 4, subfamily S, member 1
OR4S2 olfactory receptor, family 4, subfamily S, member 2
OR52E2 olfactory receptor, family 52, subfamily E, member 2
OR5A2 olfactory receptor, family 5, subfamily A, member 2
OR5D16 olfactory receptor, family 5, subfamily D, member 16
OR5D3P olfactory receptor, family 5, subfamily D, member 3 pseudogene
OR5F1 olfactory receptor, family 5, subfamily F, member 1
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
PABPC1 poly(A) binding protein, cytoplasmic 1
PACS2 phosphofurin acidic cluster sorting protein 2
PAPPA2 pappalysin 2
PASD1 PAS domain containing 1
PAXIP1 PAX interacting (with transcription-activation domain) protein 1
PCDH11X protocadherin 11 X-linked
PCDHA10 protocadherin alpha 10
PCDHGA8 protocadherin gamma subfamily A, 8
PGM2 phosphoglucomutase 2
PHOSPHO2 phosphatase, orphan 2
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PIWIL1 piwi-like RNA-mediated gene silencing 1
PLA2G4E phospholipase A2, group IVE
PLEKHH1 pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
POPDC3 popeye domain containing 3
POTEH POTE ankyrin domain family, member H
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5
PSTK phosphoseryl-tRNA kinase
PTPRS protein tyrosine phosphatase, receptor type, S
PTPRU protein tyrosine phosphatase, receptor type, U
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4
RBM11 RNA binding motif protein 11
RBM25 RNA binding motif protein 25
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
REM1 RAS (RAD and GEM)-like GTP-binding 1
REST RE1-silencing transcription factor
RFC1 replication factor C (activator 1) 1, 145kDa
RIMBP2 RIMS binding protein 2
RNF43 ring finger protein 43
RPE ribulose-5-phosphate-3-epimerase
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
SACK1G scaffolding CK1 anchoring protein G
SAMD9L sterile alpha motif domain containing 9-like
SCN11A sodium channel, voltage gated, type XI alpha subunit
SCUBE1 signal peptide, CUB domain, EGF-like 1
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
SHANK2 SH3 and multiple ankyrin repeat domains 2
SLC25A27 solute carrier family 25, member 27
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLC5A7 solute carrier family 5 (sodium/choline cotransporter), member 7
SLC6A5 solute carrier family 6 (neurotransmitter transporter), member 5
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SNTG2 syntrophin, gamma 2
SNX25 sorting nexin 25
SOBP sine oculis binding protein homolog (Drosophila)
SORCS1 sortilin-related VPS10 domain containing receptor 1
SOST sclerostin
SPAG17 sperm associated antigen 17
SPIB Spi-B transcription factor (Spi-1/PU.1 related)
STARD5 StAR-related lipid transfer (START) domain containing 5
STAT1 signal transducer and activator of transcription 1, 91kDa
STK19 serine/threonine kinase 19
STX2 syntaxin 2
STYK1 serine/threonine/tyrosine kinase 1
SYNE1 spectrin repeat containing, nuclear envelope 1
T T, brachyury homolog (mouse)
TAF8 TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TBL2 transducin (beta)-like 2
TCERG1L transcription elongation regulator 1-like
TDRD1 tudor domain containing 1
TENM1 teneurin transmembrane protein 1
TESK2 testis-specific kinase 2
THAP10 THAP domain containing 10
THRB thyroid hormone receptor, beta
TLN2 talin 2
TMEM136 transmembrane protein 136
TMEM198 transmembrane protein 198
TMOD4 tropomodulin 4 (muscle)
TNC tenascin C
TOM1L2 target of myb1-like 2 (chicken)
TOPBP1 topoisomerase (DNA) II binding protein 1
TP53 tumor protein p53
TRDN triadin
TRPM3 transient receptor potential cation channel, subfamily M, member 3
TRPS1 trichorhinophalangeal syndrome I
TSPAN17 tetraspanin 17
TTN titin
TUB tubby bipartite transcription factor
U2SURP U2 snRNP-associated SURP domain containing
UBXN2B UBX domain protein 2B
UGT3A2 UDP glycosyltransferase 3 family, polypeptide A2
USP16 ubiquitin specific peptidase 16
USP25 ubiquitin specific peptidase 25
VAC14 Vac14 homolog (S. cerevisiae)
VPS13B vacuolar protein sorting 13 homolog B (yeast)
WAC WW domain containing adaptor with coiled-coil
WDFY3 WD repeat and FYVE domain containing 3
WDR3 WD repeat domain 3
WDR33 WD repeat domain 33
WWC3 WWC family member 3
ZC3H4 zinc finger CCCH-type containing 4
ZIC1 Zic family member 1
ZNF268 zinc finger protein 268
ZNF354C zinc finger protein 354C
ZNF451 zinc finger protein 451
ZNF521 zinc finger protein 521
ZNF536 zinc finger protein 536
ZNF562 zinc finger protein 562
ZNF570 zinc finger protein 570
ZNF69 zinc finger protein 69
ZNF729 zinc finger protein 729
ZNF747 zinc finger protein 747
ZNF831 zinc finger protein 831
ZZZ3 zinc finger, ZZ-type containing 3