Macroglobulinemia Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
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Genes

256 genes co-occuring with the disease Macroglobulinemia in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
BTK Bruton agammaglobulinemia tyrosine kinase 3.329
MYD88 myeloid differentiation primary response 88 3.052
MYOM2 myomesin 2 2.822
LOC102723407 putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8 2.635
CXCR4 chemokine (C-X-C motif) receptor 4 2.592
CD79B CD79b molecule, immunoglobulin-associated beta 2.537
CD5 CD5 molecule 2.505
CD19 CD19 molecule 2.498
SDC1 syndecan 1 2.377
B2M beta-2-microglobulin 2.363
MAG myelin associated glycoprotein 2.341
CD38 CD38 molecule 2.318
MME membrane metallo-endopeptidase 2.251
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) 2.224
ITK IL2-inducible T-cell kinase 2.179
BCL2 B-cell CLL/lymphoma 2 2.176
HCK HCK proto-oncogene, Src family tyrosine kinase 2.172
IRAK4 interleukin-1 receptor-associated kinase 4 2.16
CD22 CD22 molecule 2.135
CD79A CD79a molecule, immunoglobulin-associated alpha 2.118
IRAK1 interleukin-1 receptor-associated kinase 1 2.114
CARD11 caspase recruitment domain family, member 11 2.033
SYK spleen tyrosine kinase 1.969
ALB albumin 1.964
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 1.954
TP53 tumor protein p53 1.922
BCL6 B-cell CLL/lymphoma 6 1.916
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 1.887
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.844
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.836
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase 1.828
BCR breakpoint cluster region 1.828
CXCL12 chemokine (C-X-C motif) ligand 12 1.822
PAX5 paired box 5 1.813
CCND1 cyclin D1 1.811
CD27 CD27 molecule 1.803
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 1.801
LYN LYN proto-oncogene, Src family tyrosine kinase 1.796
PRDM1 PR domain containing 1, with ZNF domain 1.787
TRAF3 TNF receptor-associated factor 3 1.786
IL6 interleukin 6 1.763
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 1.754
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 1.753
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 1.732
MALT1 MALT1 paracaspase 1.709
BMX BMX non-receptor tyrosine kinase 1.7
KMT2D lysine (K)-specific methyltransferase 2D 1.697
CD52 CD52 molecule 1.689
MCL1 myeloid cell leukemia 1 1.689
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.685
ARID1A AT rich interactive domain 1A (SWI-like) 1.682
NCAM1 neural cell adhesion molecule 1 1.681
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.677
IRF4 interferon regulatory factor 4 1.672
TXK TXK tyrosine kinase 1.668
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C 1.661
CD40 CD40 molecule, TNF receptor superfamily member 5 1.657
BLK BLK proto-oncogene, Src family tyrosine kinase 1.651
TNFRSF17 tumor necrosis factor receptor superfamily, member 17 1.647
CD4 CD4 molecule 1.639
TENT5C terminal nucleotidyltransferase 5C 1.629
BCL10 B-cell CLL/lymphoma 10 1.625
PTPRC protein tyrosine phosphatase, receptor type, C 1.624
JAK3 Janus kinase 3 1.615
EGFR epidermal growth factor receptor 1.614
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B 1.598
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 1.594
BLNK B-cell linker 1.583
PRKCB protein kinase C, beta 1.567
CD8A CD8a molecule 1.564
CD40LG CD40 ligand 1.563
CSF3 colony stimulating factor 3 (granulocyte) 1.562
BCL2L1 BCL2-like 1 1.548
BIRC3 baculoviral IAP repeat containing 3 1.547
JCHAIN joining chain of multimeric IgA and IgM 1.54
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 1.531
TNFRSF8 tumor necrosis factor receptor superfamily, member 8 1.53
SPN sialophorin 1.522
AICDA activation-induced cytidine deaminase 1.518
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease 1.507
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.498
CRBN cereblon 1.494
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 1.494
CD70 CD70 molecule 1.492
TNF tumor necrosis factor 1.491
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.473
IGLL5 immunoglobulin lambda-like polypeptide 5 1.469
CR2 complement component (3d/Epstein Barr virus) receptor 2 1.466
NOTCH1 notch 1 1.456
NOTCH2 notch 2 1.454
JAK2 Janus kinase 2 1.453
VWF von Willebrand factor 1.451
IL2 interleukin 2 1.439
CRP C-reactive protein, pentraxin-related 1.438
BCL2L11 BCL2-like 11 (apoptosis facilitator) 1.433
STOML2 stomatin (EPB72)-like 2 1.432
IL1A interleukin 1, alpha 1.413
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 1.41
SLAMF7 SLAM family member 7 1.4
IL1B interleukin 1, beta 1.399
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.391
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 1.388
HDAC9 histone deacetylase 9 1.387
CCND3 cyclin D3 1.385
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 1.382
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 1.377
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a) 1.376
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 1.373
CD37 CD37 molecule 1.37
CTRL chymotrypsin-like 1.366
PPL periplakin 1.365
BRAF B-Raf proto-oncogene, serine/threonine kinase 1.361
CD34 CD34 molecule 1.355
ALK anaplastic lymphoma receptor tyrosine kinase 1.353
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.347
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.342
CXCL13 chemokine (C-X-C motif) ligand 13 1.334
XPO1 exportin 1 1.333
IL10 interleukin 10 1.329
CXCL9 chemokine (C-X-C motif) ligand 9 1.321
PLEK2 pleckstrin 2 1.32
HLA-G major histocompatibility complex, class I, G 1.32
FLT3 fms-related tyrosine kinase 3 1.317
PARP1 poly (ADP-ribose) polymerase 1 1.314
ERBB2 erb-b2 receptor tyrosine kinase 2 1.314
IFNG interferon, gamma 1.313
PLEK pleckstrin 1.311
CREBBP CREB binding protein 1.31
A2ML1 alpha-2-macroglobulin-like 1 1.307
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 1.304
IKZF3 IKAROS family zinc finger 3 (Aiolos) 1.302
TLR9 toll-like receptor 9 1.302
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) 1.297
NSD2 nuclear receptor binding SET domain protein 2 1.296
SOX11 SRY (sex determining region Y)-box 11 1.295
TET2 tet methylcytosine dioxygenase 2 1.295
CSK c-src tyrosine kinase 1.293
CD274 CD274 molecule 1.286
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 1.276
IRAK2 interleukin-1 receptor-associated kinase 2 1.275
PPEF1 protein phosphatase, EF-hand calcium binding domain 1 1.27
TCL1B T-cell leukemia/lymphoma 1B 1.268
FCRL4 Fc receptor-like 4 1.267
CD200 CD200 molecule 1.266
EVPL envoplakin 1.265
TEC tec protein tyrosine kinase 1.265
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 1.261
TCL1A T-cell leukemia/lymphoma 1A 1.26
CCL3 chemokine (C-C motif) ligand 3 1.257
MAPK3 mitogen-activated protein kinase 3 1.257
TTR transthyretin 1.251
CAMLG calcium modulating ligand 1.24
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase 1.235
JUN jun proto-oncogene 1.228
DSG3 desmoglein 3 1.228
IL1R1 interleukin 1 receptor, type I 1.227
DUSP22 dual specificity phosphatase 22 1.227
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.226
IL6R interleukin 6 receptor 1.226
ACKR3 atypical chemokine receptor 3 1.224
GVQW3 GVQW motif containing 3 1.223
FGFR3 fibroblast growth factor receptor 3 1.222
IKZF1 IKAROS family zinc finger 1 (Ikaros) 1.211
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 1.209
CCND2 cyclin D2 1.203
IFNA1 interferon, alpha 1 1.203
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 1.198
F3 coagulation factor III (thromboplastin, tissue factor) 1.197
CD33 CD33 molecule 1.196
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 1.192
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 1.186
BCL2A1 BCL2-related protein A1 1.182
JAK1 Janus kinase 1 1.177
DSG1 desmoglein 1 1.174
MAP3K14 mitogen-activated protein kinase kinase kinase 14 1.173
CDKN2A cyclin-dependent kinase inhibitor 2A 1.17
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 1.169
EPO erythropoietin 1.169
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 1.155
DST dystonin 1.154
HDAC4 histone deacetylase 4 1.149
ERBB4 erb-b2 receptor tyrosine kinase 4 1.148
UCHL5 ubiquitin carboxyl-terminal hydrolase L5 1.147
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 1.138
MEF2B myocyte enhancer factor 2B 1.137
MYBBP1A MYB binding protein (P160) 1a 1.135
ATM ATM serine/threonine kinase 1.135
NLRP3 NLR family, pyrin domain containing 3 1.131
EPPK1 epiplakin 1 1.128
IFNA17 interferon, alpha 17 1.123
F2 coagulation factor II (thrombin) 1.123
KRAS Kirsten rat sarcoma viral oncogene homolog 1.121
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 1.116
CCL4 chemokine (C-C motif) ligand 4 1.11
BAX BCL2-associated X protein 1.106
ARID1B AT rich interactive domain 1B (SWI1-like) 1.104
TGFB1 transforming growth factor, beta 1 1.102
CEP70 centrosomal protein 70kDa 1.097
BIRC2 baculoviral IAP repeat containing 2 1.097
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.091
IFNA2 interferon, alpha 2 1.089
ASXL1 additional sex combs like transcriptional regulator 1 1.084
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.083
TLR7 toll-like receptor 7 1.083
PIK3AP1 phosphoinositide-3-kinase adaptor protein 1 1.081
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 1.08
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.079
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.078
C3 complement component 3 1.072
EP300 E1A binding protein p300 1.071
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 1.07
DSP desmoplakin 1.066
XBP1 X-box binding protein 1 1.064
SPEN spen family transcriptional repressor 1.062
MNDA myeloid cell nuclear differentiation antigen 1.062
CD2 CD2 molecule 1.06
CXCL8 chemokine (C-X-C motif) ligand 8 1.054
IFNB1 interferon, beta 1, fibroblast 1.051
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 1.05
ANPEP alanyl (membrane) aminopeptidase 1.05
CFLAR CASP8 and FADD-like apoptosis regulator 1.049
CYLD cylindromatosis (turban tumor syndrome) 1.048
H1-4 H1.4 linker histone, cluster member 1.047
ANXA5 annexin A5 1.04
PLEC plectin 1.04
AOPEP aminopeptidase O (putative) 1.039
CTLA4 cytotoxic T-lymphocyte-associated protein 4 1.038
B3GAT1 beta-1,3-glucuronyltransferase 1 1.037
DUSP5 dual specificity phosphatase 5 1.036
CHUK conserved helix-loop-helix ubiquitous kinase 1.035
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.033
FYN FYN proto-oncogene, Src family tyrosine kinase 1.033
REL v-rel avian reticuloendotheliosis viral oncogene homolog 1.031
FAS Fas cell surface death receptor 1.025
CD81 CD81 molecule 1.025
IFNA13 interferon, alpha 13 1.021
CYCS cytochrome c, somatic 1.017
RTL10 retrotransposon Gag like 10 1.016
LCK LCK proto-oncogene, Src family tyrosine kinase 1.016
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 1.013
NPPB natriuretic peptide B 1.011
TLR4 toll-like receptor 4 1.01
MPO myeloperoxidase 1.009
IFNA16 interferon, alpha 16 1.007
CCL5 chemokine (C-C motif) ligand 5 1.006
IFNA14 interferon, alpha 14 1.006
IFNA7 interferon, alpha 7 1.006
IFNA10 interferon, alpha 10 1.006
IFNA21 interferon, alpha 21 1.006
IFNA6 interferon, alpha 6 1.005
IFNA8 interferon, alpha 8 1.005
FASLG Fas ligand (TNF superfamily, member 6) 1.005
HP haptoglobin 1.005
IFNA5 interferon, alpha 5 1.004
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.002
IFNA4 interferon, alpha 4 1.0