Male infertility Gene Set

Dataset WikiPathways Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://www.wikipathways.org/pathways/WP4673.html
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Genes

145 proteins participating in the Male infertility pathway from the WikiPathways Pathways 2024 dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABLIM1 actin binding LIM protein 1
AGO2 argonaute RISC catalytic component 2
AHR aryl hydrocarbon receptor
AHRR aryl-hydrocarbon receptor repressor
APOB apolipoprotein B
AR androgen receptor
ATM ATM serine/threonine kinase
BCL2 B-cell CLL/lymphoma 2
BHMT betaine--homocysteine S-methyltransferase
BMAL1 basic helix-loop-helix ARNT like 1
BRCA2 breast cancer 2, early onset
BRDT bromodomain, testis-specific
CAT catalase
CCNA1 cyclin A1
CCNK cyclin K
CCNT1 cyclin T1
CCNT2 cyclin T2
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDK9 cyclin-dependent kinase 9
CHD2 chromodomain helicase DNA binding protein 2
CLOCK clock circadian regulator
CLU clusterin
CREBBP CREB binding protein
CRISP2 cysteine-rich secretory protein 2
CTCFL CCCTC-binding factor (zinc finger protein)-like
CXXC1 CXXC finger protein 1
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
DAZ1 deleted in azoospermia 1
DAZ2 deleted in azoospermia 2
DAZ3 deleted in azoospermia 3
DAZ4 deleted in azoospermia 4
DAZL deleted in azoospermia-like
DDX20 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
DND1 DND microRNA-mediated repression inhibitor 1
EP300 E1A binding protein p300
EPPIN epididymal peptidase inhibitor
EPSTI1 epithelial stromal interaction 1 (breast)
ERCC1 excision repair cross-complementation group 1
ERCC2 excision repair cross-complementation group 2
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
ETV5 ets variant 5
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GPX1 glutathione peroxidase 1
H2BW1 H2B.W histone 1
H3-4 H3.4 histone, cluster member
H4C1 H4 clustered histone 1
HLA-DRA major histocompatibility complex, class II, DR alpha
HMGA1 high mobility group AT-hook 1
HORMAD1 HORMA domain containing 1
HORMAD2 HORMA domain containing 2
IHO1 interactor of HORMAD1 1
INSR insulin receptor
KDM3A lysine (K)-specific demethylase 3A
KLK2 kallikrein-related peptidase 2
LIG4 ligase IV, DNA, ATP-dependent
LRWD1 leucine-rich repeats and WD repeat domain containing 1
LTF lactotransferrin
MAS1L MAS1 proto-oncogene like, G protein-coupled receptor
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MLH1 mutL homolog 1
MLH3 mutL homolog 3
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MOV10L1 Mov10 RISC complex RNA helicase like 1
MSH4 mutS homolog 4
MSH5 mutS homolog 5
MSMB microseminoprotein, beta-
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
NANOS1 nanos homolog 1 (Drosophila)
NFE2L2 nuclear factor, erythroid 2-like 2
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NQO1 NAD(P)H dehydrogenase, quinone 1
OR2W3 olfactory receptor, family 2, subfamily W, member 3
PACRG PARK2 co-regulated
PARP1 poly (ADP-ribose) polymerase 1
PEMT phosphatidylethanolamine N-methyltransferase
PEX10 peroxisomal biogenesis factor 10
PIWIL1 piwi-like RNA-mediated gene silencing 1
PIWIL2 piwi-like RNA-mediated gene silencing 2
PIWIL3 piwi-like RNA-mediated gene silencing 3
PIWIL4 piwi-like RNA-mediated gene silencing 4
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
POLB polymerase (DNA directed), beta
POLG polymerase (DNA directed), gamma
PON1 paraoxonase 1
PON2 paraoxonase 2
PRDM9 PR domain containing 9
PRM1 protamine 1
PRM2 protamine 2
PRM3 protamine 3
PRMT6 protein arginine methyltransferase 6
PSAT1 phosphoserine aminotransferase 1
PUM2 pumilio RNA-binding family member 2
RAG1 recombination activating gene 1
REC8 REC8 meiotic recombination protein
RFC1 replication factor C (activator 1) 1, 145kDa
RGS9 regulator of G-protein signaling 9
SEMG1 semenogelin I
SEPTIN12 septin 12
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SIRPA signal-regulatory protein alpha
SIRPG signal-regulatory protein gamma
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
SLC46A1 solute carrier family 46 (folate transporter), member 1
SOD2 superoxide dismutase 2, mitochondrial
SOD3 superoxide dismutase 3, extracellular
SOX5 SRY (sex determining region Y)-box 5
SPATA17 spermatogenesis associated 17
SPO11 SPO11 meiotic protein covalently bound to DSB
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
STRA8 stimulated by retinoic acid 8
TAS2R38 taste receptor, type 2, member 38
TCN2 transcobalamin II
TEX15 testis expressed 15
THBS1 thrombospondin 1
TMEM132E transmembrane protein 132E
TNF tumor necrosis factor
TRIP13 thyroid hormone receptor interactor 13
TSSK4 testis-specific serine kinase 4
TSSK6 testis-specific serine kinase 6
UBD ubiquitin D
UBE2B ubiquitin-conjugating enzyme E2B
UBR2 ubiquitin protein ligase E3 component n-recognin 2
USP26 ubiquitin specific peptidase 26
USP8 ubiquitin specific peptidase 8
VCX variable charge, X-linked
XPC xeroderma pigmentosum, complementation group C
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
YBX2 Y box binding protein 2