Malignant Melanoma Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0558356
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Genes

124 genes associated with the disease Malignant Melanoma in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABI2 abl-interactor 2
ACTRT1 actin-related protein T1
AHR aryl hydrocarbon receptor
AKT1 v-akt murine thymoma viral oncogene homolog 1
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1
ARNT aryl hydrocarbon receptor nuclear translocator
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
ATM ATM serine/threonine kinase
B2M beta-2-microglobulin
BAG3 BCL2-associated athanogene 3
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BCL2 B-cell CLL/lymphoma 2
BIRC3 baculoviral IAP repeat containing 3
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA2 breast cancer 2, early onset
C11ORF65 chromosome 11 open reading frame 65
CD177 CD177 molecule
CD274 CD274 molecule
CD80 CD80 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDK4 cyclin-dependent kinase 4
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CDKN2A cyclin-dependent kinase inhibitor 2A
CLPTM1L CLPTM1-like
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CXCR3 chemokine (C-X-C motif) receptor 3
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
CYSLTR2 cysteinyl leukotriene receptor 2
DAB2IP DAB2 interacting protein
DDR2 discoidin domain receptor tyrosine kinase 2
DOCK8 dedicator of cytokinesis 8
EGFR epidermal growth factor receptor
EIF1AX eukaryotic translation initiation factor 1A, X-linked
EPHB2 EPH receptor B2
ERBB2 erb-b2 receptor tyrosine kinase 2
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FANCA Fanconi anemia, complementation group A
FGF2 fibroblast growth factor 2 (basic)
FMN1 formin 1
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FTO fat mass and obesity associated
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
GPRC5A G protein-coupled receptor, class C, group 5, member A
HAT1 histone acetyltransferase 1
HDAC4 histone deacetylase 4
HINT2 histidine triad nucleotide binding protein 2
HSPA14 heat shock 70kDa protein 14
HSPA8 heat shock 70kDa protein 8
HSPB1 heat shock 27kDa protein 1
HSPB2 heat shock 27kDa protein 2
HSPB3 heat shock 27kDa protein 3
HSPD1 heat shock 60kDa protein 1 (chaperonin)
IFNA2 interferon, alpha 2
IFNG interferon, gamma
IL15 interleukin 15
IL2 interleukin 2
KDR kinase insert domain receptor
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KRAS Kirsten rat sarcoma viral oncogene homolog
KYAT1 kynurenine aminotransferase 1
LDLRAD4 low density lipoprotein receptor class A domain containing 4
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2
MAP2K7 mitogen-activated protein kinase kinase 7
MAPK1 mitogen-activated protein kinase 1
MAPK8 mitogen-activated protein kinase 8
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
MARCKS myristoylated alanine-rich protein kinase C substrate
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MICA MHC class I polypeptide-related sequence A
MME membrane metallo-endopeptidase
MMP2 matrix metallopeptidase 2
MTAP methylthioadenosine phosphorylase
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MX2 MX dynamin-like GTPase 2
NF1 neurofibromin 1
NFIC nuclear factor I/C (CCAAT-binding transcription factor)
NME1 NME/NM23 nucleoside diphosphate kinase 1
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
OBFC1 oligonucleotide/oligosaccharide-binding fold containing 1
OCA2 oculocutaneous albinism II
OCM oncomodulin
PDCD1 programmed cell death 1
PDCD6 programmed cell death 6
PDCD6IP programmed cell death 6 interacting protein
PERP PERP, TP53 apoptosis effector
PHPT1 phosphohistidine phosphatase 1
PIGU phosphatidylinositol glycan anchor biosynthesis, class U
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLXNA2 plexin A2
PNPLA2 patatin-like phospholipase domain containing 2
POMC proopiomelanocortin
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta
PRDX2 peroxiredoxin 2
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RMDN2 regulator of microtubule dynamics 2
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SF3B1 splicing factor 3b, subunit 1, 155kDa
SOX3 SRY (sex determining region Y)-box 3
SYNE2 spectrin repeat containing, nuclear envelope 2
TASOR2 transcription activation suppressor family member 2
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TERT telomerase reverse transcriptase
THBS2 thrombospondin 2
TLR9 toll-like receptor 9
TNF tumor necrosis factor
TP53 tumor protein p53
TTC7B tetratricopeptide repeat domain 7B
TYR tyrosinase
TYRP1 tyrosinase-related protein 1
VEGFA vascular endothelial growth factor A
WDPCP WD repeat containing planar cell polarity effector
WDR1 WD repeat domain 1
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1