| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Malotilate perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Malotilate_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.252952 |
| PLAT | plasminogen activator, tissue | 0.180023 |
| PODXL | podocalyxin-like | 0.150854 |
| MT2A | metallothionein 2A | 0.143774 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.129956 |
| FLNB | filamin B, beta | 0.102776 |
| COL3A1 | collagen, type III, alpha 1 | 0.102567 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0916842 |
| SEPTIN9 | septin 9 | 0.0793864 |
| APP | amyloid beta (A4) precursor protein | 0.0644477 |
| PTMA | prothymosin, alpha | 0.0553766 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0513089 |
| HLA-B | major histocompatibility complex, class I, B | 0.0494046 |
| COL1A2 | collagen, type I, alpha 2 | 0.0479291 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0472779 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0460465 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0429652 |
| ARRDC3 | arrestin domain containing 3 | 0.0427913 |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.04262 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0410541 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0403564 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0402633 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0395057 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0384489 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.038426 |
| S100A10 | S100 calcium binding protein A10 | 0.0370631 |
| EHBP1 | EH domain binding protein 1 | 0.0370408 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0358847 |
| PRELID2 | PRELI domain containing 2 | 0.0351136 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0345792 |
| EZR | ezrin | 0.032716 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0325214 |
| BCL2L1 | BCL2-like 1 | 0.0313971 |
| FNBP1 | formin binding protein 1 | 0.0304906 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0304408 |
| RPL37A | ribosomal protein L37a | 0.0299786 |
| COL5A1 | collagen, type V, alpha 1 | 0.0299337 |
| SFTPA2 | surfactant protein A2 | 0.0297786 |
| ATP13A3 | ATPase type 13A3 | 0.0290385 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0290381 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.028798 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0286112 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0283361 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0282451 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | 0.0280696 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0280245 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0279567 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0275633 |
| MCL1 | myeloid cell leukemia 1 | 0.0274314 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0269504 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.02683 |
| SUCNR1 | succinate receptor 1 | 0.0268136 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0263459 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.0260487 |
| MYOF | myoferlin | 0.025773 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0246995 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0246517 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0246153 |
| TMSB4X | thymosin beta 4, X-linked | 0.0243708 |
| STC1 | stanniocalcin 1 | 0.0243095 |
| REST | RE1-silencing transcription factor | 0.023555 |
| FBN1 | fibrillin 1 | 0.0233302 |
| CDK19 | cyclin-dependent kinase 19 | 0.0232676 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0232401 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0229745 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0221388 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0221296 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0221079 |
| NMT1 | N-myristoyltransferase 1 | 0.0214427 |
| RPS3 | ribosomal protein S3 | 0.0211568 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0208641 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0204536 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.019991 |
| CALD1 | caldesmon 1 | 0.0198602 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0196795 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0194347 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0193503 |
| ASPH | aspartate beta-hydroxylase | 0.0192509 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0191787 |
| FRMD4A | FERM domain containing 4A | 0.0189534 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0188035 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0185815 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0185748 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0185362 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | 0.018517 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0184738 |
| MYADM | myeloid-associated differentiation marker | 0.0183545 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0182119 |
| SET | SET nuclear proto-oncogene | 0.0181997 |
| TMOD1 | tropomodulin 1 | 0.0180689 |
| CTSB | cathepsin B | 0.0180411 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0179938 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0178519 |
| SHLD2 | shieldin complex subunit 2 | 0.0178492 |
| EEA1 | early endosome antigen 1 | 0.0177919 |
| KLF6 | Kruppel-like factor 6 | 0.0174596 |
| MRC2 | mannose receptor, C type 2 | 0.017368 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0173648 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0172913 |
| RPS2 | ribosomal protein S2 | 0.0172501 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.279362 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.228385 |
| POTEF | POTE ankyrin domain family, member F | -0.115203 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.114801 |
| MAP1B | microtubule-associated protein 1B | -0.109331 |
| ANXA2 | annexin A2 | -0.0807145 |
| AHNAK | AHNAK nucleoprotein | -0.0789572 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.072552 |
| TMSB10 | thymosin beta 10 | -0.0722614 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0641533 |
| UBC | ubiquitin C | -0.0635968 |
| CDH13 | cadherin 13 | -0.0625808 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0623079 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0596727 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0587394 |
| LOX | lysyl oxidase | -0.0570207 |
| MEIS2 | Meis homeobox 2 | -0.0563712 |
| TAGLN2 | transgelin 2 | -0.0530799 |
| PKM | pyruvate kinase, muscle | -0.0521248 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0515334 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0512529 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0509575 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0498953 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0496029 |
| COPA | coatomer protein complex, subunit alpha | -0.045734 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0455452 |
| RIGI | RNA sensor RIG-I | -0.045483 |
| TAPBP | TAP binding protein (tapasin) | -0.0449195 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0444168 |
| CCND1 | cyclin D1 | -0.0438597 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0424935 |
| BSG | basigin (Ok blood group) | -0.0423005 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0419308 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0418291 |
| RTN4 | reticulon 4 | -0.0415035 |
| PFN1 | profilin 1 | -0.0401736 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.03827 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0381573 |
| GOLGA4 | golgin A4 | -0.0374873 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0374009 |
| CANX | calnexin | -0.0372818 |
| ZNF207 | zinc finger protein 207 | -0.036855 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0367053 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0366966 |
| FSTL1 | follistatin-like 1 | -0.0359657 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0357187 |
| TAOK1 | TAO kinase 1 | -0.0355719 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | -0.035333 |
| S100A6 | S100 calcium binding protein A6 | -0.0339575 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.033812 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0335071 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0332714 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0331924 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0330674 |
| SP100 | SP100 nuclear antigen | -0.0327479 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0321295 |
| LDHA | lactate dehydrogenase A | -0.0312855 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0310613 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0307156 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0306035 |
| TGFB1 | transforming growth factor, beta 1 | -0.0303654 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0302979 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0302925 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0300095 |
| RND3 | Rho family GTPase 3 | -0.0299352 |
| SERTAD2 | SERTA domain containing 2 | -0.0296478 |
| QKI | QKI, KH domain containing, RNA binding | -0.0293051 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0291452 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0284403 |
| AFAP1 | actin filament associated protein 1 | -0.0278573 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0276296 |
| FADS2 | fatty acid desaturase 2 | -0.0272483 |
| INSIG1 | insulin induced gene 1 | -0.0269371 |
| FTL | ferritin, light polypeptide | -0.0267272 |
| MSI2 | musashi RNA-binding protein 2 | -0.0265156 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0260877 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | -0.0260369 |
| HBP1 | HMG-box transcription factor 1 | -0.0258271 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.0256133 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0255588 |
| POGZ | pogo transposable element with ZNF domain | -0.0253279 |
| SEPTIN7 | septin 7 | -0.0252459 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | -0.025057 |
| MNT | MAX network transcriptional repressor | -0.024985 |
| TPM4 | tropomyosin 4 | -0.0248793 |
| SMIM44 | small integral membrane protein 44 | -0.0248504 |
| RPL28 | ribosomal protein L28 | -0.0247072 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0246052 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0244878 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0238496 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0236094 |
| ADM | adrenomedullin | -0.0234858 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -0.0234662 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0231902 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0231668 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0230624 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | -0.0226344 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | -0.0226262 |
| ZFP36 | ZFP36 ring finger protein | -0.0225785 |
| CDK6 | cyclin-dependent kinase 6 | -0.0224547 |
