| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Malotilate perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Malotilate_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | 0.240464 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.140159 |
| PTMA | prothymosin, alpha | 0.121768 |
| SEPTIN9 | septin 9 | 0.0923817 |
| RPL23 | ribosomal protein L23 | 0.0907393 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0849779 |
| FNBP1 | formin binding protein 1 | 0.0741659 |
| RPL37A | ribosomal protein L37a | 0.0686672 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0655947 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0648505 |
| RPL19 | ribosomal protein L19 | 0.0643396 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0577089 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0546229 |
| COL3A1 | collagen, type III, alpha 1 | 0.0544771 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0542189 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0528947 |
| RPL26 | ribosomal protein L26 | 0.0496804 |
| PLAT | plasminogen activator, tissue | 0.0477645 |
| RPS27A | ribosomal protein S27a | 0.0476203 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0461438 |
| SET | SET nuclear proto-oncogene | 0.0443856 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0435741 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0413505 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0408893 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0408077 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0407546 |
| RPS24 | ribosomal protein S24 | 0.0397202 |
| LPIN1 | lipin 1 | 0.0394609 |
| RPL38 | ribosomal protein L38 | 0.0378471 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0377266 |
| RPS29 | ribosomal protein S29 | 0.0372651 |
| CLTC | clathrin, heavy chain (Hc) | 0.0372094 |
| FAM13A | family with sequence similarity 13, member A | 0.0369029 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0367002 |
| RPLP1 | ribosomal protein, large, P1 | 0.0362509 |
| TBX2 | T-box 2 | 0.0356742 |
| VIM | vimentin | 0.0356097 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0354381 |
| S100A6 | S100 calcium binding protein A6 | 0.0348492 |
| COL1A1 | collagen, type I, alpha 1 | 0.0348022 |
| RPS12 | ribosomal protein S12 | 0.0342565 |
| AFDN | afadin, adherens junction formation factor | 0.0340878 |
| RPL36A | ribosomal protein L36a | 0.0334202 |
| COL18A1 | collagen, type XVIII, alpha 1 | 0.0331033 |
| RPS6 | ribosomal protein S6 | 0.0329877 |
| ZNF292 | zinc finger protein 292 | 0.0327802 |
| CTSB | cathepsin B | 0.0324992 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0318519 |
| SRP14 | signal recognition particle 14kDa (homologous Alu RNA binding protein) | 0.0304681 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0304074 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0302604 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0300993 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0296149 |
| RPL5 | ribosomal protein L5 | 0.0294182 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0291324 |
| AOPEP | aminopeptidase O (putative) | 0.0290592 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0287254 |
| S100A9 | S100 calcium binding protein A9 | 0.0283963 |
| SLFN5 | schlafen family member 5 | 0.0283576 |
| AHR | aryl hydrocarbon receptor | 0.0282182 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0281431 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0279913 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0278246 |
| MORF4L2 | mortality factor 4 like 2 | 0.0277576 |
| B2M | beta-2-microglobulin | 0.0274307 |
| KLF6 | Kruppel-like factor 6 | 0.0271933 |
| RPL12 | ribosomal protein L12 | 0.0265433 |
| TOP1 | topoisomerase (DNA) I | 0.0259198 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0254823 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0253956 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0252799 |
| RPL30 | ribosomal protein L30 | 0.0252301 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0251132 |
| JMJD1C | jumonji domain containing 1C | 0.0251029 |
| MEF2A | myocyte enhancer factor 2A | 0.0249695 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.0247861 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.024763 |
| SRP72 | signal recognition particle 72kDa | 0.0244902 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0240985 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0240669 |
| RNF213 | ring finger protein 213 | 0.0239808 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0239437 |
| LMNA | lamin A/C | 0.0238986 |
| RPL7A | ribosomal protein L7a | 0.0235872 |
| HNRNPUL1 | heterogeneous nuclear ribonucleoprotein U-like 1 | 0.0234793 |
| TXNIP | thioredoxin interacting protein | 0.0234592 |
| RPL32 | ribosomal protein L32 | 0.0233651 |
| FUS | FUS RNA binding protein | 0.0233415 |
| RPL34 | ribosomal protein L34 | 0.0233221 |
| PCTP | phosphatidylcholine transfer protein | 0.0232336 |
| RPL36 | ribosomal protein L36 | 0.0231501 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.023112 |
| RPS4X | ribosomal protein S4, X-linked | 0.0231015 |
| ILF3 | interleukin enhancer binding factor 3, 90kDa | 0.0227897 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0226682 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0225673 |
| RPS27 | ribosomal protein S27 | 0.0225671 |
| RPS8 | ribosomal protein S8 | 0.0224047 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.0222626 |
| SNX4 | sorting nexin 4 | 0.0221983 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.27632 |
| SYT1 | synaptotagmin I | -0.12383 |
| VCL | vinculin | -0.113496 |
| FMN1 | formin 1 | -0.0986232 |
| MEIS2 | Meis homeobox 2 | -0.0939815 |
| NRG1 | neuregulin 1 | -0.0893374 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0830734 |
| VMP1 | vacuole membrane protein 1 | -0.0830011 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0649037 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0645374 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0626874 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0591842 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0586506 |
| KLHL13 | kelch-like family member 13 | -0.0582212 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0580002 |
| TLE4 | transducin-like enhancer of split 4 | -0.0554954 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0526332 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0493734 |
| MAP1B | microtubule-associated protein 1B | -0.0489878 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0481683 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0480251 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0455595 |
| MED13 | mediator complex subunit 13 | -0.0440454 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0432827 |
| GREM2 | gremlin 2, DAN family BMP antagonist | -0.0432687 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0432146 |
| STK38L | serine/threonine kinase 38 like | -0.0427145 |
| SIK2 | salt-inducible kinase 2 | -0.0426604 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0416499 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0414361 |
| FERMT2 | fermitin family member 2 | -0.0405599 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0403181 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0402571 |
| GLCCI1 | glucocorticoid induced 1 | -0.0400377 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0398802 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.039366 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0391538 |
| UNC5C | unc-5 homolog C (C. elegans) | -0.0391414 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0384044 |
| CADM2 | cell adhesion molecule 2 | -0.0379275 |
| MAPK10 | mitogen-activated protein kinase 10 | -0.0375087 |
| FHIT | fragile histidine triad | -0.0373565 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0371366 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | -0.0370981 |
| POTEF | POTE ankyrin domain family, member F | -0.0369118 |
| FRMD4A | FERM domain containing 4A | -0.0355636 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0353887 |
| EGR1 | early growth response 1 | -0.0348511 |
| PLPP1 | phospholipid phosphatase 1 | -0.0345268 |
| PTEN | phosphatase and tensin homolog | -0.0342915 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0339538 |
| KCNIP4 | Kv channel interacting protein 4 | -0.0328933 |
| GOLGB1 | golgin B1 | -0.0328756 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.032565 |
| PARD3 | par-3 family cell polarity regulator | -0.0325421 |
| SLITRK6 | SLIT and NTRK-like family, member 6 | -0.0324032 |
| RBM39 | RNA binding motif protein 39 | -0.0322242 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0316767 |
| NEK1 | NIMA-related kinase 1 | -0.0315627 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.0313002 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0312586 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0308747 |
| TPM1 | tropomyosin 1 (alpha) | -0.0307542 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0305382 |
| TRIB2 | tribbles pseudokinase 2 | -0.0304497 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0302652 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0301943 |
| ZNF207 | zinc finger protein 207 | -0.030107 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0300846 |
| RNF150 | ring finger protein 150 | -0.0300187 |
| COPA | coatomer protein complex, subunit alpha | -0.0299393 |
| UBAP1 | ubiquitin associated protein 1 | -0.0297169 |
| RBM26 | RNA binding motif protein 26 | -0.0295649 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0294184 |
| CCNL1 | cyclin L1 | -0.0292662 |
| AUTS2 | autism susceptibility candidate 2 | -0.0290193 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.0288841 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0286795 |
| UBAP2 | ubiquitin associated protein 2 | -0.0286795 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0284978 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0278514 |
| MCL1 | myeloid cell leukemia 1 | -0.0276756 |
| CNTN4 | contactin 4 | -0.0276608 |
| ACTG1 | actin gamma 1 | -0.0275877 |
| ATRNL1 | attractin-like 1 | -0.0272242 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0272156 |
| PDS5B | PDS5 cohesin associated factor B | -0.0270855 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | -0.0270033 |
| SIK3 | SIK family kinase 3 | -0.0268491 |
| WDR26 | WD repeat domain 26 | -0.0266044 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0265241 |
| TGFB1 | transforming growth factor, beta 1 | -0.0264888 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0263883 |
| THBS1 | thrombospondin 1 | -0.0263014 |
| PRKCA | protein kinase C, alpha | -0.0261393 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0260098 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0260006 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0259159 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0258187 |
| PHIP | pleckstrin homology domain interacting protein | -0.0257585 |
