| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Malotilate perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Malotilate_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.204644 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0962157 |
| NDRG1 | N-myc downstream regulated 1 | 0.0866901 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0780998 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0745198 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0660916 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0657666 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0581986 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0580376 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0568655 |
| RNF149 | ring finger protein 149 | 0.0564789 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0556522 |
| DIAPH3 | diaphanous-related formin 3 | 0.0485312 |
| H1-0 | H1.0 linker histone | 0.0473369 |
| DSPP | dentin sialophosphoprotein | 0.0472131 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0469065 |
| AHNAK | AHNAK nucleoprotein | 0.0466868 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0445833 |
| MKI67 | marker of proliferation Ki-67 | 0.0438696 |
| TXNIP | thioredoxin interacting protein | 0.0435588 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0428902 |
| PTEN | phosphatase and tensin homolog | 0.0425277 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0412193 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0409943 |
| RNF43 | ring finger protein 43 | 0.0407821 |
| PRELID2 | PRELI domain containing 2 | 0.0407636 |
| ARRDC3 | arrestin domain containing 3 | 0.0404683 |
| RUNX1 | runt-related transcription factor 1 | 0.0404346 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0392555 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.0391436 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0380535 |
| OGA | O-GlcNAcase | 0.0380393 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0372695 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0361363 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.0360752 |
| AOPEP | aminopeptidase O (putative) | 0.0350257 |
| MEIS2 | Meis homeobox 2 | 0.0340304 |
| CALR | calreticulin | 0.0337388 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0328858 |
| EHF | ets homologous factor | 0.0328702 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0327611 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0327425 |
| RRBP1 | ribosome binding protein 1 | 0.0327123 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0320569 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.0320232 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0318732 |
| APOL1 | apolipoprotein L, 1 | 0.0314025 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0310979 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0306799 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0305217 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0304865 |
| TMEM51 | transmembrane protein 51 | 0.0302917 |
| HDLBP | high density lipoprotein binding protein | 0.0297461 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0293772 |
| CCNL1 | cyclin L1 | 0.029181 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0291111 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0291046 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0288367 |
| FLNB | filamin B, beta | 0.0285733 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0283486 |
| DNM2 | dynamin 2 | 0.0282832 |
| SLC2A12 | solute carrier family 2 (facilitated glucose transporter), member 12 | 0.0280699 |
| YEATS2 | YEATS domain containing 2 | 0.0274556 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0274283 |
| GRAMD2B | GRAM domain containing 2B | 0.0274082 |
| DYNC2I1 | dynein 2 intermediate chain 1 | 0.0273349 |
| XPO1 | exportin 1 | 0.0272881 |
| ANLN | anillin, actin binding protein | 0.0270791 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0268879 |
| SBF2 | SET binding factor 2 | 0.0268102 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0265442 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0263377 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0262721 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0262 |
| GRK3 | G protein-coupled receptor kinase 3 | 0.0261925 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0260403 |
| SH3PXD2A | SH3 and PX domains 2A | 0.02556 |
| TJP2 | tight junction protein 2 | 0.0255148 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0255109 |
| HYOU1 | hypoxia up-regulated 1 | 0.0254517 |
| H1-10 | H1.10 linker histone | 0.0249138 |
| WDR45B | WD repeat domain 45B | 0.0248597 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0247089 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0247068 |
| TMPRSS4 | transmembrane protease, serine 4 | 0.0247044 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0243237 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | 0.0242626 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0242054 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0241758 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0240203 |
| IFNGR1 | interferon gamma receptor 1 | 0.0239383 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0238358 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0237211 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0236571 |
| CENPF | centromere protein F, 350/400kDa | 0.0236054 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0234021 |
| ATP11B | ATPase, class VI, type 11B | 0.0233899 |
| ZNF638 | zinc finger protein 638 | 0.0233765 |
| RAPGEF1 | Rap guanine nucleotide exchange factor (GEF) 1 | 0.023182 |
| TPI1 | triosephosphate isomerase 1 | 0.0231226 |
| Symbol | Name | Standardized Value |
|---|---|---|
| INTS6 | integrator complex subunit 6 | -0.177091 |
| ANXA2 | annexin A2 | -0.141749 |
| LYZ | lysozyme | -0.120217 |
| LMO7 | LIM domain 7 | -0.118224 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.116592 |
| VCL | vinculin | -0.115776 |
| EGR1 | early growth response 1 | -0.105351 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.103448 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.099999 |
| PLSCR2 | phospholipid scramblase 2 | -0.0957042 |
| PHF3 | PHD finger protein 3 | -0.0935507 |
| TM4SF19 | transmembrane 4 L six family member 19 | -0.0889956 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0855171 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.083305 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0822474 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0810318 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0810103 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0799623 |
| RIGI | RNA sensor RIG-I | -0.0794895 |
| MAP7 | microtubule-associated protein 7 | -0.0779826 |
| SP100 | SP100 nuclear antigen | -0.075142 |
| MX1 | MX dynamin-like GTPase 1 | -0.0748153 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0725812 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0723656 |
| PERP | PERP, TP53 apoptosis effector | -0.0704324 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0699125 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0653674 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.063962 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0626818 |
| POU2F2 | POU class 2 homeobox 2 | -0.0621583 |
| SMAD3 | SMAD family member 3 | -0.059918 |
| PLSCR1 | phospholipid scramblase 1 | -0.0594322 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0571691 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0569988 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0553892 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0552456 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0551408 |
| MX2 | MX dynamin-like GTPase 2 | -0.0551327 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0549419 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0542407 |
| AREG | amphiregulin | -0.0529064 |
| MCU | mitochondrial calcium uniporter | -0.052406 |
| MCL1 | myeloid cell leukemia 1 | -0.0502933 |
| TNS4 | tensin 4 | -0.0501274 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0493535 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0486992 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0486661 |
| UBAP2 | ubiquitin associated protein 2 | -0.0486118 |
| PMP22 | peripheral myelin protein 22 | -0.0485735 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0484783 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0474395 |
| TJP1 | tight junction protein 1 | -0.04726 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0466707 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0459349 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0453742 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -0.045062 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0449402 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | -0.0447031 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0443562 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0442978 |
| ACTG1 | actin gamma 1 | -0.0433983 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0429341 |
| GOLGB1 | golgin B1 | -0.042818 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0411937 |
| IRS2 | insulin receptor substrate 2 | -0.0411559 |
| XAF1 | XIAP associated factor 1 | -0.0396477 |
| RPL7L1 | ribosomal protein L7-like 1 | -0.0395623 |
| SETX | senataxin | -0.0393032 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.039235 |
| LAMA4 | laminin, alpha 4 | -0.0390265 |
| VMP1 | vacuole membrane protein 1 | -0.0385436 |
| POF1B | premature ovarian failure, 1B | -0.0382532 |
| ERBIN | erbb2 interacting protein | -0.0378606 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0376458 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0376276 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0375564 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0372472 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0366572 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0365923 |
| LRRC8A | leucine rich repeat containing 8 family, member A | -0.036421 |
| MUC20 | mucin 20, cell surface associated | -0.036128 |
| DIAPH1 | diaphanous-related formin 1 | -0.0356959 |
| BCL2L1 | BCL2-like 1 | -0.0354744 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0352527 |
| SPATA13 | spermatogenesis associated 13 | -0.0344787 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0342528 |
| NABP1 | nucleic acid binding protein 1 | -0.0339396 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0333052 |
| USP53 | ubiquitin specific peptidase 53 | -0.0325676 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.0320287 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0318477 |
| PKM | pyruvate kinase, muscle | -0.0314533 |
| FOSL1 | FOS-like antigen 1 | -0.0311296 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0310017 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | -0.0309815 |
| RNF213 | ring finger protein 213 | -0.0309604 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0308196 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0307924 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0307862 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0303451 |
