| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Malotilate perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Malotilate_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.258123 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.114695 |
| PTMA | prothymosin, alpha | 0.0950692 |
| SET | SET nuclear proto-oncogene | 0.0913412 |
| EZR | ezrin | 0.0898818 |
| TMSB4X | thymosin beta 4, X-linked | 0.0799057 |
| RAI1 | retinoic acid induced 1 | 0.0731552 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.070761 |
| RPS3 | ribosomal protein S3 | 0.0628862 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0622951 |
| RPS12 | ribosomal protein S12 | 0.0608601 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0575111 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0558485 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0547715 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0545096 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0544474 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0533965 |
| RPL23 | ribosomal protein L23 | 0.0512639 |
| FLNB | filamin B, beta | 0.0508971 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0505698 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0498257 |
| USP34 | ubiquitin specific peptidase 34 | 0.0487895 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0486256 |
| RPS4X | ribosomal protein S4, X-linked | 0.0477616 |
| APP | amyloid beta (A4) precursor protein | 0.0472874 |
| ANGPTL4 | angiopoietin-like 4 | 0.0468014 |
| DOCK11 | dedicator of cytokinesis 11 | 0.0464333 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.045947 |
| RPL3 | ribosomal protein L3 | 0.0455647 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.044405 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0433834 |
| RPL26 | ribosomal protein L26 | 0.0426343 |
| ARRDC3 | arrestin domain containing 3 | 0.0418 |
| RPL37A | ribosomal protein L37a | 0.0417289 |
| KRT18 | keratin 18, type I | 0.04158 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0413512 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0406836 |
| RBM25 | RNA binding motif protein 25 | 0.0399825 |
| SQSTM1 | sequestosome 1 | 0.038563 |
| CDK19 | cyclin-dependent kinase 19 | 0.0378719 |
| PAIP2 | poly(A) binding protein interacting protein 2 | 0.037652 |
| RPS27A | ribosomal protein S27a | 0.0373463 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0369201 |
| MKI67 | marker of proliferation Ki-67 | 0.0365556 |
| KLF6 | Kruppel-like factor 6 | 0.0360595 |
| YEATS2 | YEATS domain containing 2 | 0.0359859 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0359125 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0358223 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0352903 |
| TPI1 | triosephosphate isomerase 1 | 0.0348643 |
| RPS8 | ribosomal protein S8 | 0.034815 |
| MT2A | metallothionein 2A | 0.0338665 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0338382 |
| SERINC1 | serine incorporator 1 | 0.0336783 |
| CALR | calreticulin | 0.0336287 |
| ACTN1 | actinin, alpha 1 | 0.0335235 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0324373 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0323489 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0321355 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0316808 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0312979 |
| RPL5 | ribosomal protein L5 | 0.030803 |
| THOC2 | THO complex 2 | 0.0300592 |
| RACK1 | receptor for activated C kinase 1 | 0.0299031 |
| FNBP1 | formin binding protein 1 | 0.0297272 |
| MINK1 | misshapen-like kinase 1 | 0.0297154 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0294099 |
| SRGN | serglycin | 0.0292456 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0285374 |
| ILF3 | interleukin enhancer binding factor 3, 90kDa | 0.0279698 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.027834 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0275329 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0272709 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0270107 |
| RPL12 | ribosomal protein L12 | 0.0269845 |
| CENPF | centromere protein F, 350/400kDa | 0.0269612 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0268876 |
| TPRG1 | tumor protein p63 regulated 1 | 0.0268861 |
| RPS17 | ribosomal protein S17 | 0.026621 |
| HDGF | hepatoma-derived growth factor | 0.026386 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0263643 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0263283 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0262924 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.026245 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.024883 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0248268 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0244898 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0244542 |
| GTF2I | general transcription factor IIi | 0.0243917 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0243481 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0242268 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | 0.0241943 |
| RPS23 | ribosomal protein S23 | 0.0240626 |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) | 0.0240456 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0237284 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | 0.0233574 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0230935 |
| TPM3 | tropomyosin 3 | 0.023073 |
| NONO | non-POU domain containing, octamer-binding | 0.0228411 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0227004 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.370584 |
| POTEF | POTE ankyrin domain family, member F | -0.133725 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.108184 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.087659 |
| CD44 | CD44 molecule (Indian blood group) | -0.0860772 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.084258 |
| TP63 | tumor protein p63 | -0.0831653 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0768152 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0672947 |
| ACTG1 | actin gamma 1 | -0.0657643 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0647465 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0602199 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0550063 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0544261 |
| TMSB10 | thymosin beta 10 | -0.0505178 |
| HMGA1 | high mobility group AT-hook 1 | -0.0503453 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0482169 |
| EGR1 | early growth response 1 | -0.0471785 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0471011 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0445049 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0433474 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0419387 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0418638 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.040647 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.040358 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.039731 |
| TXNIP | thioredoxin interacting protein | -0.0384849 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.038087 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0380443 |
| CADM2 | cell adhesion molecule 2 | -0.0374476 |
| JMJD1C | jumonji domain containing 1C | -0.037398 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0373231 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0355969 |
| FTL | ferritin, light polypeptide | -0.035368 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0345631 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | -0.0342887 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0337312 |
| OLA1 | Obg-like ATPase 1 | -0.0336312 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0332868 |
| RPLP0 | ribosomal protein, large, P0 | -0.0328209 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0324958 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0323595 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0321139 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0318289 |
| QKI | QKI, KH domain containing, RNA binding | -0.0314879 |
| TAOK1 | TAO kinase 1 | -0.0309705 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0305022 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0303885 |
| SP100 | SP100 nuclear antigen | -0.0299603 |
| ANXA2 | annexin A2 | -0.0293141 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0290199 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0288643 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0286586 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0285117 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0281056 |
| INTS6 | integrator complex subunit 6 | -0.0277603 |
| HOMER1 | homer scaffolding protein 1 | -0.0273755 |
| WASF2 | WAS protein family, member 2 | -0.0271943 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0267339 |
| TNS3 | tensin 3 | -0.0265528 |
| RCOR1 | REST corepressor 1 | -0.0263746 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0263073 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0261398 |
| H1-0 | H1.0 linker histone | -0.0259907 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0257797 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0256391 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0253966 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0251811 |
| SRPK2 | SRSF protein kinase 2 | -0.0251147 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0249881 |
| TGM2 | transglutaminase 2 | -0.0249244 |
| RTN3 | reticulon 3 | -0.0246039 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0245989 |
| RPL39 | ribosomal protein L39 | -0.0245475 |
| MYOF | myoferlin | -0.0239918 |
| PARD3 | par-3 family cell polarity regulator | -0.0239507 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0238963 |
| MT1X | metallothionein 1X | -0.0238762 |
| ZNF207 | zinc finger protein 207 | -0.0236816 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.02356 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0233066 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0232842 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0232092 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.02308 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0230719 |
| RPLP1 | ribosomal protein, large, P1 | -0.0229935 |
| SRP54 | signal recognition particle 54kDa | -0.0229035 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0228927 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0228645 |
| PLIN2 | perilipin 2 | -0.0224881 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0222505 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | -0.0221243 |
| HBS1L | HBS1-like translational GTPase | -0.0219347 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0216478 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0215651 |
| CAPRIN2 | caprin family member 2 | -0.0215381 |
| BMPR1A | bone morphogenetic protein receptor, type IA | -0.0213447 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | -0.0210612 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0210564 |
| RIGI | RNA sensor RIG-I | -0.0207601 |
