| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Malotilate perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Malotilate_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.118626 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0986629 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0884115 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0808064 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0770442 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0740126 |
| RPL3 | ribosomal protein L3 | 0.0721754 |
| GOLGA4 | golgin A4 | 0.0702871 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0641119 |
| LOX | lysyl oxidase | 0.063534 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0584354 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0564093 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0552997 |
| USP34 | ubiquitin specific peptidase 34 | 0.0519433 |
| FLNB | filamin B, beta | 0.0510376 |
| HDLBP | high density lipoprotein binding protein | 0.0502806 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0493904 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0480294 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0466988 |
| APP | amyloid beta (A4) precursor protein | 0.046338 |
| DOCK5 | dedicator of cytokinesis 5 | 0.046328 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0450899 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0450744 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0443005 |
| FAM13A | family with sequence similarity 13, member A | 0.0437478 |
| COPA | coatomer protein complex, subunit alpha | 0.0434426 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0422233 |
| SPAG9 | sperm associated antigen 9 | 0.0418009 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0413862 |
| ARRDC3 | arrestin domain containing 3 | 0.0411907 |
| NGLY1 | N-glycanase 1 | 0.0411468 |
| ATP13A3 | ATPase type 13A3 | 0.0411253 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0403649 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0400701 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | 0.0397388 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.0394111 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0390799 |
| SUCO | SUN domain containing ossification factor | 0.0390686 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.038731 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0378319 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0377073 |
| CALU | calumenin | 0.0376059 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0375721 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.037499 |
| GOLGA2 | golgin A2 | 0.0374933 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0368876 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0368117 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0366876 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0356693 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0356068 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0350481 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0349959 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0349283 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0344721 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0343078 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0341552 |
| SETD5 | SET domain containing 5 | 0.0338697 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0334609 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | 0.0333163 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0319266 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0317333 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0316004 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0315629 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0315467 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0313885 |
| PCBP2 | poly(rC) binding protein 2 | 0.0312074 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0311253 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.030966 |
| YEATS2 | YEATS domain containing 2 | 0.030944 |
| CALR | calreticulin | 0.0308245 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0302396 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0301377 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0300535 |
| PFKP | phosphofructokinase, platelet | 0.0300512 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0297809 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0292717 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0287337 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0287109 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0284594 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0283411 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0282527 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0281636 |
| RAB5A | RAB5A, member RAS oncogene family | 0.0280961 |
| HM13 | histocompatibility (minor) 13 | 0.0280503 |
| SIK3 | SIK family kinase 3 | 0.0279218 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0278833 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0276445 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0274824 |
| SEPTIN2 | septin 2 | 0.0272774 |
| FOXO3 | forkhead box O3 | 0.026939 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0268349 |
| RNF24 | ring finger protein 24 | 0.0267584 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0265181 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0261516 |
| SRP54 | signal recognition particle 54kDa | 0.026053 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0259404 |
| FMNL2 | formin-like 2 | 0.0257558 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0256063 |
| COG5 | component of oligomeric golgi complex 5 | 0.025479 |
| OPTN | optineurin | 0.0254132 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.243152 |
| MT2A | metallothionein 2A | -0.133855 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.120773 |
| FTL | ferritin, light polypeptide | -0.117141 |
| VIM | vimentin | -0.112206 |
| TMSB10 | thymosin beta 10 | -0.108123 |
| RPLP1 | ribosomal protein, large, P1 | -0.103102 |
| CDH13 | cadherin 13 | -0.082902 |
| RPL35A | ribosomal protein L35a | -0.0692694 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0640422 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0624976 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0624193 |
| RPS19 | ribosomal protein S19 | -0.0611233 |
| RPL32 | ribosomal protein L32 | -0.0586163 |
| EFNA5 | ephrin-A5 | -0.0585153 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0585106 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.056135 |
| RPS8 | ribosomal protein S8 | -0.055324 |
| SYT1 | synaptotagmin I | -0.0548823 |
| CD44 | CD44 molecule (Indian blood group) | -0.0521044 |
| GPC6 | glypican 6 | -0.0492521 |
| RPS29 | ribosomal protein S29 | -0.0477583 |
| RPLP2 | ribosomal protein, large, P2 | -0.046245 |
| RPL31 | ribosomal protein L31 | -0.0453823 |
| HMGA2 | high mobility group AT-hook 2 | -0.0445623 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0444648 |
| RPS24 | ribosomal protein S24 | -0.0444379 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.043727 |
| RPS6 | ribosomal protein S6 | -0.043639 |
| RPL28 | ribosomal protein L28 | -0.0431295 |
| EGR1 | early growth response 1 | -0.0418191 |
| RPS21 | ribosomal protein S21 | -0.0417494 |
| RPL34 | ribosomal protein L34 | -0.0416008 |
| IER3 | immediate early response 3 | -0.0415323 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0410909 |
| RPLP0 | ribosomal protein, large, P0 | -0.0409979 |
| CDCP1 | CUB domain containing protein 1 | -0.0405346 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0388574 |
| RPL37A | ribosomal protein L37a | -0.0383482 |
| ASPH | aspartate beta-hydroxylase | -0.0381016 |
| NRG1 | neuregulin 1 | -0.0370597 |
| RPL12 | ribosomal protein L12 | -0.0357414 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0352147 |
| RAD51B | RAD51 paralog B | -0.034279 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0341677 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0328791 |
| SUMF1 | sulfatase modifying factor 1 | -0.0321991 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0321324 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0317481 |
| RPS13 | ribosomal protein S13 | -0.0316982 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.031445 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0314172 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0312183 |
| B2M | beta-2-microglobulin | -0.0311827 |
| OXR1 | oxidation resistance 1 | -0.0308807 |
| KCTD16 | potassium channel tetramerization domain containing 16 | -0.030846 |
| HMGA1 | high mobility group AT-hook 1 | -0.0307969 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0305592 |
| RPS16 | ribosomal protein S16 | -0.030502 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0304845 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0301005 |
| RPL23 | ribosomal protein L23 | -0.0293898 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | -0.0293895 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.0292774 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0292197 |
| RPL13A | ribosomal protein L13a | -0.0285246 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0283828 |
| RPS25 | ribosomal protein S25 | -0.0283174 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0282298 |
| FOXP1 | forkhead box P1 | -0.02789 |
| ACTG1 | actin gamma 1 | -0.027683 |
| RPL36 | ribosomal protein L36 | -0.0269518 |
| ATP5MC2 | ATP synthase membrane subunit c locus 2 | -0.0268903 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0267593 |
| DST | dystonin | -0.0267483 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0262728 |
| ATG7 | autophagy related 7 | -0.0259081 |
| PHF14 | PHD finger protein 14 | -0.0259004 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0258334 |
| ATXN1 | ataxin 1 | -0.0254791 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0252711 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0252625 |
| MAP1B | microtubule-associated protein 1B | -0.0251492 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.02506 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0250018 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0249635 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0248199 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0247594 |
| RPS5 | ribosomal protein S5 | -0.0244171 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0243078 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0240772 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0240432 |
| RPL11 | ribosomal protein L11 | -0.0238806 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0238003 |
| RPS12 | ribosomal protein S12 | -0.0235801 |
| EXOC4 | exocyst complex component 4 | -0.0235228 |
| ZNF804A | zinc finger protein 804A | -0.0235177 |
| VCL | vinculin | -0.0234134 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0232377 |
| LMAN1 | lectin, mannose-binding, 1 | -0.023166 |
