| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Malotilate perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Malotilate_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.257146 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.119717 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.118501 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0837758 |
| ACTN1 | actinin, alpha 1 | 0.0792381 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0718602 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0679682 |
| FMNL2 | formin-like 2 | 0.0634328 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0629873 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0602597 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0566552 |
| FLNB | filamin B, beta | 0.0563259 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0559873 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0550057 |
| MKI67 | marker of proliferation Ki-67 | 0.0547814 |
| VIM | vimentin | 0.0541427 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0496794 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0496734 |
| CMIP | c-Maf inducing protein | 0.0478207 |
| HDGF | hepatoma-derived growth factor | 0.0469213 |
| COPA | coatomer protein complex, subunit alpha | 0.0468929 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0466428 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.046434 |
| FAM107B | family with sequence similarity 107, member B | 0.0458466 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0448702 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0447384 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0442809 |
| APP | amyloid beta (A4) precursor protein | 0.0421562 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0409974 |
| TPX2 | TPX2, microtubule-associated | 0.0408963 |
| RPL3 | ribosomal protein L3 | 0.0408357 |
| TPM3 | tropomyosin 3 | 0.0401744 |
| LDHA | lactate dehydrogenase A | 0.0396924 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.0396092 |
| PHF20 | PHD finger protein 20 | 0.037149 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0346149 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0342917 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.033639 |
| SETD5 | SET domain containing 5 | 0.0329288 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0328431 |
| KIF5B | kinesin family member 5B | 0.0325249 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0322213 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0319568 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0319446 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0315245 |
| RPS12 | ribosomal protein S12 | 0.0315211 |
| COG5 | component of oligomeric golgi complex 5 | 0.0314121 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0310599 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0309704 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0307555 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0307259 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0305431 |
| NUP58 | nucleoporin 58 | 0.0305053 |
| RPS17 | ribosomal protein S17 | 0.0303797 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | 0.0302836 |
| ANLN | anillin, actin binding protein | 0.030145 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0298991 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0292608 |
| PYGL | phosphorylase, glycogen, liver | 0.0292226 |
| STMN1 | stathmin 1 | 0.0291945 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0291735 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0289812 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0288596 |
| AKAP10 | A kinase (PRKA) anchor protein 10 | 0.0286027 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0283799 |
| SET | SET nuclear proto-oncogene | 0.0282515 |
| HMOX1 | heme oxygenase 1 | 0.0278775 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0275116 |
| FDPS | farnesyl diphosphate synthase | 0.0274169 |
| PTMA | prothymosin, alpha | 0.027304 |
| FERMT2 | fermitin family member 2 | 0.0268561 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.0267112 |
| YY1 | YY1 transcription factor | 0.0266544 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0261984 |
| RFWD3 | ring finger and WD repeat domain 3 | 0.0261961 |
| KIF23 | kinesin family member 23 | 0.0260855 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0260635 |
| YBX1 | Y box binding protein 1 | 0.0259508 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0259134 |
| RPS4X | ribosomal protein S4, X-linked | 0.025884 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.0253418 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0252913 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0251929 |
| SNX14 | sorting nexin 14 | 0.0249643 |
| CUX1 | cut-like homeobox 1 | 0.0249193 |
| ECT2 | epithelial cell transforming 2 | 0.0248166 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.0248026 |
| SEPTIN7 | septin 7 | 0.0246061 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0245594 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0245504 |
| THOC2 | THO complex 2 | 0.0243519 |
| NOP58 | NOP58 ribonucleoprotein | 0.0242275 |
| ITSN1 | intersectin 1 (SH3 domain protein) | 0.0241855 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0240059 |
| IGF2 | insulin-like growth factor 2 | 0.0239238 |
| ERBIN | erbb2 interacting protein | 0.0238843 |
| UBE2C | ubiquitin-conjugating enzyme E2C | 0.0238502 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0237319 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0237164 |
| STC2 | stanniocalcin 2 | 0.023454 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.235936 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.227696 |
| FTL | ferritin, light polypeptide | -0.211887 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.193136 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.164898 |
| RPLP1 | ribosomal protein, large, P1 | -0.0762822 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0703871 |
| TXNRD1 | thioredoxin reductase 1 | -0.0685585 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0671785 |
| RPL35A | ribosomal protein L35a | -0.0624153 |
| EGR1 | early growth response 1 | -0.0602774 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0566818 |
| RPS19 | ribosomal protein S19 | -0.0549068 |
| BICC1 | BicC family RNA binding protein 1 | -0.0544438 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0527818 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0522838 |
| RPS21 | ribosomal protein S21 | -0.0518798 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0498581 |
| PFN1 | profilin 1 | -0.0492214 |
| IER3 | immediate early response 3 | -0.0469378 |
| HMGA1 | high mobility group AT-hook 1 | -0.0467604 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0464536 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0461812 |
| FGB | fibrinogen beta chain | -0.0437192 |
| USP3 | ubiquitin specific peptidase 3 | -0.0434925 |
| GLIS3 | GLIS family zinc finger 3 | -0.0434912 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.03961 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0390218 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0368035 |
| RPL31 | ribosomal protein L31 | -0.035964 |
| WWOX | WW domain containing oxidoreductase | -0.0354345 |
| EFNA5 | ephrin-A5 | -0.034778 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0347236 |
| RPS23 | ribosomal protein S23 | -0.034244 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0340264 |
| RPL13A | ribosomal protein L13a | -0.033605 |
| RPLP0 | ribosomal protein, large, P0 | -0.0329041 |
| GOLM2 | golgi membrane protein 2 | -0.0316224 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0315272 |
| DST | dystonin | -0.0314012 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0307237 |
| RTN4 | reticulon 4 | -0.0307155 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0306491 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0304736 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0302965 |
| RPS20 | ribosomal protein S20 | -0.0300492 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0295191 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0292076 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0291374 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0285059 |
| METAP2 | methionyl aminopeptidase 2 | -0.0281342 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0278611 |
| NEGR1 | neuronal growth regulator 1 | -0.0277509 |
| POTEF | POTE ankyrin domain family, member F | -0.0277326 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.02725 |
| JAK1 | Janus kinase 1 | -0.0271165 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0270563 |
| NTN4 | netrin 4 | -0.0260636 |
| RPL11 | ribosomal protein L11 | -0.0259252 |
| RAB7A | RAB7A, member RAS oncogene family | -0.02571 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | -0.0256442 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0254503 |
| ZNF292 | zinc finger protein 292 | -0.02537 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0253326 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.025259 |
| SRSF7 | serine/arginine-rich splicing factor 7 | -0.0251939 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0251822 |
| BMP5 | bone morphogenetic protein 5 | -0.0251173 |
| RIGI | RNA sensor RIG-I | -0.0248338 |
| SMYD3 | SET and MYND domain containing 3 | -0.0246652 |
| SVIL | supervillin | -0.0245958 |
| NAV3 | neuron navigator 3 | -0.0245703 |
| RPL19 | ribosomal protein L19 | -0.0244767 |
| RPS29 | ribosomal protein S29 | -0.0243965 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0241862 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0240525 |
| B2M | beta-2-microglobulin | -0.0238273 |
| FGG | fibrinogen gamma chain | -0.0235088 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0233297 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0232127 |
| HMGB1 | high mobility group box 1 | -0.0231347 |
| OSBPL9 | oxysterol binding protein-like 9 | -0.0231278 |
| GABARAPL2 | GABA(A) receptor-associated protein-like 2 | -0.0229019 |
| OSMR | oncostatin M receptor | -0.0226174 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0225496 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.0224429 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0224372 |
| S100A11 | S100 calcium binding protein A11 | -0.0224107 |
| RPS16 | ribosomal protein S16 | -0.0220649 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0218727 |
| RPL34 | ribosomal protein L34 | -0.0218118 |
| RPS24 | ribosomal protein S24 | -0.021694 |
| OLA1 | Obg-like ATPase 1 | -0.021656 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0214311 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0211253 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0210947 |
| GRAMD1B | GRAM domain containing 1B | -0.0210924 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0209636 |
| PARD3B | par-3 family cell polarity regulator beta | -0.020911 |
| ANXA2 | annexin A2 | -0.0205565 |
