| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Malotilate perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Malotilate_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.165962 |
| PTMA | prothymosin, alpha | 0.158678 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.133893 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.11894 |
| CALR | calreticulin | 0.110252 |
| NDRG1 | N-myc downstream regulated 1 | 0.107832 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.1067 |
| FN1 | fibronectin 1 | 0.104517 |
| ARRDC3 | arrestin domain containing 3 | 0.0694565 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0690675 |
| TMSB4X | thymosin beta 4, X-linked | 0.0608053 |
| PLEC | plectin | 0.058053 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0556625 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.052522 |
| LAMB3 | laminin, beta 3 | 0.0519445 |
| TPI1 | triosephosphate isomerase 1 | 0.0479963 |
| EPCAM | epithelial cell adhesion molecule | 0.0471757 |
| HMGB2 | high mobility group box 2 | 0.0468268 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0462144 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0457773 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0455376 |
| TOP1 | topoisomerase (DNA) I | 0.0450027 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0449559 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0445703 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0433703 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0410779 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0390966 |
| FAM162A | family with sequence similarity 162, member A | 0.0390601 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0388744 |
| EZR | ezrin | 0.0385627 |
| LDHA | lactate dehydrogenase A | 0.0384826 |
| APP | amyloid beta (A4) precursor protein | 0.0377108 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0367084 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0364177 |
| RPS4X | ribosomal protein S4, X-linked | 0.0350354 |
| MORF4L2 | mortality factor 4 like 2 | 0.0335554 |
| NUP58 | nucleoporin 58 | 0.0324939 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0319556 |
| G0S2 | G0/G1 switch 2 | 0.0309705 |
| RPL3 | ribosomal protein L3 | 0.0308754 |
| CALU | calumenin | 0.0307608 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0300761 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0297525 |
| HDLBP | high density lipoprotein binding protein | 0.0293813 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0293656 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0291111 |
| SDC4 | syndecan 4 | 0.0288179 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0283077 |
| MXD1 | MAX dimerization protein 1 | 0.0279074 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0278422 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0277267 |
| ASPH | aspartate beta-hydroxylase | 0.0276203 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0275226 |
| RBM25 | RNA binding motif protein 25 | 0.0273411 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0263559 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0261952 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0258382 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0258327 |
| PGK1 | phosphoglycerate kinase 1 | 0.0254156 |
| UBC | ubiquitin C | 0.0252819 |
| TFG | TRK-fused gene | 0.0252516 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0250248 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0249637 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0248361 |
| SLC38A1 | solute carrier family 38, member 1 | 0.024425 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0242402 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0239027 |
| KRT18 | keratin 18, type I | 0.0237181 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0235988 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0233468 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0232222 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0231752 |
| CAVIN1 | caveolae associated protein 1 | 0.0226218 |
| SET | SET nuclear proto-oncogene | 0.0225494 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0225423 |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) | 0.0224278 |
| NAP1L4 | nucleosome assembly protein 1-like 4 | 0.0220953 |
| TPX2 | TPX2, microtubule-associated | 0.0220534 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0220078 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0220051 |
| G3BP2 | GTPase activating protein (SH3 domain) binding protein 2 | 0.0218895 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0217422 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0216688 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0216652 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0216632 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0213042 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0211937 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0211268 |
| COPA | coatomer protein complex, subunit alpha | 0.0210305 |
| LMNA | lamin A/C | 0.020788 |
| HLA-E | major histocompatibility complex, class I, E | 0.0206848 |
| FLNB | filamin B, beta | 0.0203786 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0202876 |
| CCDC47 | coiled-coil domain containing 47 | 0.0201507 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.020093 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0199057 |
| MT2A | metallothionein 2A | 0.0198092 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0196516 |
| LAMC2 | laminin, gamma 2 | 0.0195946 |
| SERINC1 | serine incorporator 1 | 0.0194456 |
| Symbol | Name | Standardized Value |
|---|---|---|
| POTEF | POTE ankyrin domain family, member F | -0.157942 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.149253 |
| ACTG1 | actin gamma 1 | -0.0921783 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0884835 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.087653 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0747246 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0737522 |
| EFNA5 | ephrin-A5 | -0.0690061 |
| KRT7 | keratin 7, type II | -0.0649506 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0636672 |
| ERBIN | erbb2 interacting protein | -0.0635955 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0588059 |
| DTNA | dystrobrevin, alpha | -0.0582416 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0530407 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0512525 |
| FBXO32 | F-box protein 32 | -0.0483645 |
| HMGA1 | high mobility group AT-hook 1 | -0.0479934 |
| RAI14 | retinoic acid induced 14 | -0.0478161 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0466742 |
| MAP1B | microtubule-associated protein 1B | -0.0462067 |
| RPLP0 | ribosomal protein, large, P0 | -0.0444528 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0443246 |
| FHIT | fragile histidine triad | -0.0435569 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0425218 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.041818 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0414471 |
| CCND1 | cyclin D1 | -0.0403713 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0393782 |
| FTL | ferritin, light polypeptide | -0.0392148 |
| DSG2 | desmoglein 2 | -0.039082 |
| RPS6 | ribosomal protein S6 | -0.0389711 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0377513 |
| PTK2 | protein tyrosine kinase 2 | -0.0374236 |
| PLSCR1 | phospholipid scramblase 1 | -0.0373128 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.0365586 |
| RPS23 | ribosomal protein S23 | -0.036492 |
| RPS13 | ribosomal protein S13 | -0.0360546 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0357364 |
| GOLGB1 | golgin B1 | -0.0353849 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0352197 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | -0.0351641 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.0347747 |
| NAV2 | neuron navigator 2 | -0.0344856 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0335639 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0334216 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0330363 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0324722 |
| MX2 | MX dynamin-like GTPase 2 | -0.0316722 |
| RPS25 | ribosomal protein S25 | -0.0313416 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.031171 |
| EGFR | epidermal growth factor receptor | -0.0310094 |
| PGBD5 | piggyBac transposable element derived 5 | -0.0305608 |
| RPS2 | ribosomal protein S2 | -0.0304989 |
| RPLP2 | ribosomal protein, large, P2 | -0.0304092 |
| ARHGAP20 | Rho GTPase activating protein 20 | -0.0302704 |
| RPL19 | ribosomal protein L19 | -0.0301388 |
| RPL35A | ribosomal protein L35a | -0.0300866 |
| RAD51B | RAD51 paralog B | -0.0299212 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0299142 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0298357 |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha | -0.0297266 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0291972 |
| PATJ | PATJ crumbs cell polarity complex component | -0.029005 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0288226 |
| ATXN1 | ataxin 1 | -0.0281012 |
| NR3C2 | nuclear receptor subfamily 3, group C, member 2 | -0.0280941 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0279964 |
| ETV6 | ets variant 6 | -0.0278815 |
| RASA2 | RAS p21 protein activator 2 | -0.0277971 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0277659 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0274745 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0273416 |
| LMO7 | LIM domain 7 | -0.0272144 |
| FNIP1 | folliculin interacting protein 1 | -0.0269162 |
| RPL7 | ribosomal protein L7 | -0.0267591 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.026636 |
| MYO1E | myosin IE | -0.0265981 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.026534 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0264972 |
| RPS8 | ribosomal protein S8 | -0.0262242 |
| RPS10 | ribosomal protein S10 | -0.0258375 |
| TJP1 | tight junction protein 1 | -0.0257829 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0257456 |
| SEPTIN11 | septin 11 | -0.0257197 |
| OCLN | occludin | -0.0257131 |
| TSC22D2 | TSC22 domain family, member 2 | -0.025666 |
| SQSTM1 | sequestosome 1 | -0.0256258 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0254425 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0251977 |
| VCL | vinculin | -0.0251583 |
| RPL30 | ribosomal protein L30 | -0.0251166 |
| PALLD | palladin, cytoskeletal associated protein | -0.0249946 |
| SH3RF1 | SH3 domain containing ring finger 1 | -0.024766 |
| RASAL2 | RAS protein activator like 2 | -0.0246471 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0244633 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0243005 |
| ANO6 | anoctamin 6 | -0.0241838 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0238711 |
| MCU | mitochondrial calcium uniporter | -0.0234933 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0234396 |
