| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Malotilate perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Malotilate_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.18346 |
| MCL1 | myeloid cell leukemia 1 | 0.148548 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.147614 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.115603 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0846383 |
| RPL3 | ribosomal protein L3 | 0.0824564 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0762887 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0755456 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0741611 |
| FLNB | filamin B, beta | 0.0724089 |
| STC1 | stanniocalcin 1 | 0.0570908 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0555123 |
| SET | SET nuclear proto-oncogene | 0.0545028 |
| MFF | mitochondrial fission factor | 0.054421 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0528941 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0516653 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0508187 |
| VIM | vimentin | 0.0501866 |
| MSN | moesin | 0.0497541 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0478216 |
| GRAMD1B | GRAM domain containing 1B | 0.0469336 |
| NDRG1 | N-myc downstream regulated 1 | 0.0464259 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0464188 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0456395 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.044036 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0431384 |
| PYGL | phosphorylase, glycogen, liver | 0.0430256 |
| TMX4 | thioredoxin-related transmembrane protein 4 | 0.0428581 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.041957 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0406663 |
| LDHA | lactate dehydrogenase A | 0.0405398 |
| TPI1 | triosephosphate isomerase 1 | 0.0398968 |
| EZR | ezrin | 0.0398577 |
| PKM | pyruvate kinase, muscle | 0.0397943 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0394363 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0382186 |
| INHBA | inhibin, beta A | 0.0371451 |
| CTSL | cathepsin L | 0.036777 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.0355484 |
| CD44 | CD44 molecule (Indian blood group) | 0.0344494 |
| LAMB1 | laminin, beta 1 | 0.0344353 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0337764 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0331135 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0316324 |
| IL6 | interleukin 6 | 0.0311596 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0310715 |
| APP | amyloid beta (A4) precursor protein | 0.0309115 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.030762 |
| BMERB1 | bMERB domain containing 1 | 0.0306951 |
| MKI67 | marker of proliferation Ki-67 | 0.0305562 |
| MYOF | myoferlin | 0.0301525 |
| SFTPA2 | surfactant protein A2 | 0.0299535 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.029866 |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.0296365 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0294546 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.029394 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0287838 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.028752 |
| TPM3 | tropomyosin 3 | 0.0287273 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0285317 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0282768 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0282003 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0281568 |
| ARRDC3 | arrestin domain containing 3 | 0.0279016 |
| CD109 | CD109 molecule | 0.0275472 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0274752 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0274584 |
| HDLBP | high density lipoprotein binding protein | 0.0271841 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0271816 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0264083 |
| USP34 | ubiquitin specific peptidase 34 | 0.0263988 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0259991 |
| RPS4X | ribosomal protein S4, X-linked | 0.0259136 |
| ENO1 | enolase 1, (alpha) | 0.0258674 |
| TOB1 | transducer of ERBB2, 1 | 0.0258341 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.025833 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0255901 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0254918 |
| KRT19 | keratin 19, type I | 0.0253378 |
| RGS2 | regulator of G-protein signaling 2 | 0.024954 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0246596 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.024602 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0246012 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0244139 |
| NONO | non-POU domain containing, octamer-binding | 0.0243563 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0241301 |
| SLK | STE20-like kinase | 0.024121 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0238304 |
| FLNA | filamin A, alpha | 0.0237091 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0235277 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0230445 |
| HLA-A | major histocompatibility complex, class I, A | 0.0227748 |
| EGR1 | early growth response 1 | 0.0226778 |
| COPA | coatomer protein complex, subunit alpha | 0.0226337 |
| PGK1 | phosphoglycerate kinase 1 | 0.022332 |
| SLC16A6 | solute carrier family 16, member 6 | 0.0222527 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0221896 |
| ITGA6 | integrin, alpha 6 | 0.0218738 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0217992 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0211208 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.216446 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.140183 |
| FTL | ferritin, light polypeptide | -0.12206 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0985034 |
| CDH13 | cadherin 13 | -0.0870291 |
| PDE10A | phosphodiesterase 10A | -0.0865989 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0806411 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0802325 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0764749 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0715788 |
| SMYD3 | SET and MYND domain containing 3 | -0.0683364 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.061885 |
| ASPH | aspartate beta-hydroxylase | -0.0615583 |
| TMSB10 | thymosin beta 10 | -0.0549294 |
| RPS24 | ribosomal protein S24 | -0.0535094 |
| TXNRD1 | thioredoxin reductase 1 | -0.0527514 |
| PTMA | prothymosin, alpha | -0.0504766 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0489295 |
| RPLP1 | ribosomal protein, large, P1 | -0.0475965 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0469535 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0468373 |
| RPL19 | ribosomal protein L19 | -0.0468138 |
| RPLP0 | ribosomal protein, large, P0 | -0.044828 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0439439 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.041955 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0401113 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0397121 |
| RBM39 | RNA binding motif protein 39 | -0.0389193 |
| RPL23 | ribosomal protein L23 | -0.0384646 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0372746 |
| WDR43 | WD repeat domain 43 | -0.0367496 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0365398 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0360905 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0357488 |
| TNPO1 | transportin 1 | -0.0350469 |
| DST | dystonin | -0.0348779 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0344029 |
| RPL35A | ribosomal protein L35a | -0.0340819 |
| S100A10 | S100 calcium binding protein A10 | -0.0327475 |
| NEK7 | NIMA-related kinase 7 | -0.0316165 |
| USP3 | ubiquitin specific peptidase 3 | -0.0315554 |
| NCKAP5 | NCK-associated protein 5 | -0.0310834 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0309524 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.030813 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0306311 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.030606 |
| RPL26 | ribosomal protein L26 | -0.0304229 |
| RPS19 | ribosomal protein S19 | -0.0300298 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0298525 |
| RPL12 | ribosomal protein L12 | -0.0294713 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.029302 |
| CADM2 | cell adhesion molecule 2 | -0.0288011 |
| RNF145 | ring finger protein 145 | -0.0287912 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0280691 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0276966 |
| RTN4 | reticulon 4 | -0.0269088 |
| INTS6 | integrator complex subunit 6 | -0.0267913 |
| RPL37A | ribosomal protein L37a | -0.0267249 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.02621 |
| OLA1 | Obg-like ATPase 1 | -0.0259351 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0258519 |
| LSAMP | limbic system-associated membrane protein | -0.0257267 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0257246 |
| ADGRD1 | adhesion G protein-coupled receptor D1 | -0.0256169 |
| RPLP2 | ribosomal protein, large, P2 | -0.0255829 |
| RPL13A | ribosomal protein L13a | -0.0255243 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0252157 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0251687 |
| RPS25 | ribosomal protein S25 | -0.024945 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0247486 |
| ACTG1 | actin gamma 1 | -0.0244718 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0241962 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0236581 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0235314 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0235233 |
| IER3 | immediate early response 3 | -0.0233688 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0231848 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0228891 |
| VCL | vinculin | -0.0226812 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0225758 |
| NOP58 | NOP58 ribonucleoprotein | -0.0222716 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0222695 |
| RPS23 | ribosomal protein S23 | -0.0221264 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0220726 |
| RPS27A | ribosomal protein S27a | -0.0219453 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0218583 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.021489 |
| MEMO1 | mediator of cell motility 1 | -0.0214126 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0213415 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0212485 |
| RPS13 | ribosomal protein S13 | -0.021172 |
| RPS8 | ribosomal protein S8 | -0.0211419 |
| RPL34 | ribosomal protein L34 | -0.0211374 |
| ZNF207 | zinc finger protein 207 | -0.0209967 |
| PRDX1 | peroxiredoxin 1 | -0.0207662 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0207487 |
| JMJD1C | jumonji domain containing 1C | -0.0207011 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0206773 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0204224 |
| RHEB | Ras homolog enriched in brain | -0.0204023 |
