| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Malotilate perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Malotilate_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | 0.267384 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.202315 |
| RPS16 | ribosomal protein S16 | 0.193669 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.183489 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.173798 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.154984 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.120526 |
| FN1 | fibronectin 1 | 0.120464 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.117983 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.113909 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.10205 |
| PGK1 | phosphoglycerate kinase 1 | 0.088929 |
| ADAR | adenosine deaminase, RNA-specific | 0.0846286 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0833147 |
| USP34 | ubiquitin specific peptidase 34 | 0.082037 |
| STC1 | stanniocalcin 1 | 0.081921 |
| MT2A | metallothionein 2A | 0.0806229 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0804632 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.078962 |
| SPAG9 | sperm associated antigen 9 | 0.0782929 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0782564 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.078106 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0747831 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0740348 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0735846 |
| PHF21A | PHD finger protein 21A | 0.0698987 |
| GNAS | GNAS complex locus | 0.0675502 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0673324 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0671236 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0664893 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0646519 |
| FMNL2 | formin-like 2 | 0.0618681 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0607694 |
| PKM | pyruvate kinase, muscle | 0.0607327 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0596684 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0578485 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0572396 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0571583 |
| PDE8A | phosphodiesterase 8A | 0.0562865 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0553578 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0526504 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0510432 |
| ATXN1 | ataxin 1 | 0.049139 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0471999 |
| B2M | beta-2-microglobulin | 0.0459607 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0448023 |
| RPS8 | ribosomal protein S8 | 0.0447666 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0445232 |
| FTL | ferritin, light polypeptide | 0.0438027 |
| ZNF207 | zinc finger protein 207 | 0.0426801 |
| JMJD1C | jumonji domain containing 1C | 0.0420474 |
| RPS12 | ribosomal protein S12 | 0.0405617 |
| CD44 | CD44 molecule (Indian blood group) | 0.0393877 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0392289 |
| CDK13 | cyclin-dependent kinase 13 | 0.0390001 |
| H1-0 | H1.0 linker histone | 0.0383104 |
| RPL11 | ribosomal protein L11 | 0.038051 |
| UBC | ubiquitin C | 0.0380009 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.037346 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0359038 |
| TMEM123 | transmembrane protein 123 | 0.0356824 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.034847 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0347966 |
| CCNI | cyclin I | 0.0343663 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0339131 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0337179 |
| CALU | calumenin | 0.0330566 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0329795 |
| RPLP2 | ribosomal protein, large, P2 | 0.0323733 |
| ZNF292 | zinc finger protein 292 | 0.0310913 |
| CALR | calreticulin | 0.0303057 |
| RPL8 | ribosomal protein L8 | 0.0292255 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0288706 |
| TAOK1 | TAO kinase 1 | 0.0286841 |
| RAB2A | RAB2A, member RAS oncogene family | 0.0279006 |
| RAB1A | RAB1A, member RAS oncogene family | 0.027837 |
| RBM25 | RNA binding motif protein 25 | 0.0276633 |
| RBM39 | RNA binding motif protein 39 | 0.0276302 |
| RSF1 | remodeling and spacing factor 1 | 0.0272409 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0271548 |
| KLF6 | Kruppel-like factor 6 | 0.0269368 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0266794 |
| RPS13 | ribosomal protein S13 | 0.025854 |
| GOLGA4 | golgin A4 | 0.0243577 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0242881 |
| ADM | adrenomedullin | 0.0238457 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0234184 |
| RPL34 | ribosomal protein L34 | 0.0233777 |
| OSMR | oncostatin M receptor | 0.0232882 |
| TPI1 | triosephosphate isomerase 1 | 0.0231879 |
| LAMB3 | laminin, beta 3 | 0.0225806 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0220839 |
| RPS19 | ribosomal protein S19 | 0.0218572 |
| ERBIN | erbb2 interacting protein | 0.0216674 |
| RPS3 | ribosomal protein S3 | 0.0210883 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0208689 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0198452 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0193379 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0190371 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0183071 |
| Symbol | Name | Standardized Value |
|---|---|---|
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.13824 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.133788 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.113921 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.104963 |
| CANX | calnexin | -0.102042 |
| VMP1 | vacuole membrane protein 1 | -0.0995973 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0950412 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0942904 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0931751 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0909425 |
| GOLGB1 | golgin B1 | -0.0906778 |
| ZNF608 | zinc finger protein 608 | -0.0829341 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0794932 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0790854 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0788885 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0772721 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0771422 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.074546 |
| PRKCA | protein kinase C, alpha | -0.0712138 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.069706 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0695937 |
| MATR3 | matrin 3 | -0.0680558 |
| BBX | bobby sox homolog (Drosophila) | -0.0679521 |
| HELZ | helicase with zinc finger | -0.0678566 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0672009 |
| ANXA2 | annexin A2 | -0.0670449 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0664531 |
| POTEF | POTE ankyrin domain family, member F | -0.0610381 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.059532 |
| EFNA5 | ephrin-A5 | -0.0593259 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.058861 |
| MYOF | myoferlin | -0.0565876 |
| UBAC2 | UBA domain containing 2 | -0.0544162 |
| PDS5A | PDS5 cohesin associated factor A | -0.053159 |
| HMGA2 | high mobility group AT-hook 2 | -0.0530926 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0529124 |
| PTK2 | protein tyrosine kinase 2 | -0.0523193 |
| TXNRD1 | thioredoxin reductase 1 | -0.0513526 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0498941 |
| RNF213 | ring finger protein 213 | -0.0493896 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0492523 |
| FAM13A | family with sequence similarity 13, member A | -0.0489364 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0487188 |
| PDE10A | phosphodiesterase 10A | -0.0486789 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0475879 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0470351 |
| CADM2 | cell adhesion molecule 2 | -0.0455047 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0446763 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0440755 |
| EGR1 | early growth response 1 | -0.0428488 |
| TJP1 | tight junction protein 1 | -0.0427329 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.041825 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0412901 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0410059 |
| FLNB | filamin B, beta | -0.0405598 |
| MYO10 | myosin X | -0.0405485 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0402102 |
| SLTM | SAFB-like, transcription modulator | -0.0393517 |
| ATP11A | ATPase, class VI, type 11A | -0.0386609 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0371687 |
| SMYD3 | SET and MYND domain containing 3 | -0.0368871 |
| RORA | RAR-related orphan receptor A | -0.0367142 |
| DNER | delta/notch-like EGF repeat containing | -0.0362162 |
| FNIP1 | folliculin interacting protein 1 | -0.035678 |
| MED13L | mediator complex subunit 13-like | -0.0355494 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0352164 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0349571 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0335352 |
| KIF5B | kinesin family member 5B | -0.0330506 |
| FOXP1 | forkhead box P1 | -0.031585 |
| HDAC9 | histone deacetylase 9 | -0.0312573 |
| AHNAK | AHNAK nucleoprotein | -0.0310022 |
| EXOC4 | exocyst complex component 4 | -0.0309818 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0306904 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0299867 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0295959 |
| YEATS2 | YEATS domain containing 2 | -0.0295013 |
| NF1 | neurofibromin 1 | -0.0291479 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0272773 |
| ITGA6 | integrin, alpha 6 | -0.0270594 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0269724 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0266196 |
| ASPH | aspartate beta-hydroxylase | -0.0265592 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0260974 |
| MSI2 | musashi RNA-binding protein 2 | -0.0255182 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0251173 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0249881 |
| RAD51B | RAD51 paralog B | -0.0247058 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0245906 |
| OGA | O-GlcNAcase | -0.0245632 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0245579 |
| RABGAP1 | RAB GTPase activating protein 1 | -0.0244499 |
| GPC6 | glypican 6 | -0.0241718 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0239178 |
| CDH13 | cadherin 13 | -0.0232906 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0229939 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0229916 |
| H3-3B | H3.3 histone B | -0.0229101 |
| RPL31 | ribosomal protein L31 | -0.0225473 |
| SETD5 | SET domain containing 5 | -0.021349 |
