| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Malotilate perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Malotilate_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.112217 |
| NDRG1 | N-myc downstream regulated 1 | 0.103507 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0999345 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0945784 |
| MT2A | metallothionein 2A | 0.0926951 |
| VIM | vimentin | 0.083737 |
| VEGFA | vascular endothelial growth factor A | 0.0733565 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0689439 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0652269 |
| FLNB | filamin B, beta | 0.0610993 |
| HLA-B | major histocompatibility complex, class I, B | 0.0581158 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0541049 |
| CD44 | CD44 molecule (Indian blood group) | 0.0490461 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0433867 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0419492 |
| EGFR | epidermal growth factor receptor | 0.0402271 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0395456 |
| SEPTIN9 | septin 9 | 0.0394403 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 0.0391939 |
| FMNL2 | formin-like 2 | 0.0385138 |
| C3 | complement component 3 | 0.0377812 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0377298 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0373726 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0370939 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0370134 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0369206 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.034817 |
| STC1 | stanniocalcin 1 | 0.0343524 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0343085 |
| ARRDC3 | arrestin domain containing 3 | 0.0339433 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0334744 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0334467 |
| MCL1 | myeloid cell leukemia 1 | 0.0333513 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0327287 |
| HDAC9 | histone deacetylase 9 | 0.0325726 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.032403 |
| GPC6 | glypican 6 | 0.0315372 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0310915 |
| CDK19 | cyclin-dependent kinase 19 | 0.0310757 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0305338 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0304489 |
| FRMPD4 | FERM and PDZ domain containing 4 | 0.0301157 |
| FLOT1 | flotillin 1 | 0.030059 |
| HLA-A | major histocompatibility complex, class I, A | 0.0300276 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0300035 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.029642 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0296174 |
| RPL9 | ribosomal protein L9 | 0.0294083 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0291858 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0289773 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0274869 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0274248 |
| RND3 | Rho family GTPase 3 | 0.0272408 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0271874 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0269991 |
| GOLGA4 | golgin A4 | 0.0269736 |
| B2M | beta-2-microglobulin | 0.0269256 |
| PHF21A | PHD finger protein 21A | 0.0268287 |
| MYO10 | myosin X | 0.026483 |
| HMGA2 | high mobility group AT-hook 2 | 0.0263882 |
| RPS4X | ribosomal protein S4, X-linked | 0.0261659 |
| PDE10A | phosphodiesterase 10A | 0.025939 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0258983 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0258315 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0257875 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0256387 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.025635 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0252813 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0252034 |
| TGM2 | transglutaminase 2 | 0.0251346 |
| RNF24 | ring finger protein 24 | 0.0248415 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0247066 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0244928 |
| INHBA | inhibin, beta A | 0.0244203 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0242563 |
| INSR | insulin receptor | 0.0239451 |
| FBXO32 | F-box protein 32 | 0.0239386 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0239062 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | 0.023561 |
| FRMD4A | FERM domain containing 4A | 0.0230566 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0230308 |
| JMJD1C | jumonji domain containing 1C | 0.0228709 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0228156 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0227709 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0226273 |
| PLIN2 | perilipin 2 | 0.0223269 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | 0.0222584 |
| RUNX1 | runt-related transcription factor 1 | 0.0221601 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0220783 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0220055 |
| BNC2 | basonuclin 2 | 0.0219276 |
| NOTCH2 | notch 2 | 0.0218809 |
| DUSP5 | dual specificity phosphatase 5 | 0.0217225 |
| BPTF | bromodomain PHD finger transcription factor | 0.0216974 |
| EFNA5 | ephrin-A5 | 0.0216066 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0214867 |
| MSN | moesin | 0.0210744 |
| CCNL1 | cyclin L1 | 0.0209918 |
| MMP12 | matrix metallopeptidase 12 | 0.0208655 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0208628 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | -0.171752 |
| FN1 | fibronectin 1 | -0.154163 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.141969 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.103765 |
| IER3 | immediate early response 3 | -0.0939057 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0930689 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0874902 |
| PGK1 | phosphoglycerate kinase 1 | -0.0851565 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.07986 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0732191 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0664742 |
| THBS1 | thrombospondin 1 | -0.0640782 |
| ANXA2 | annexin A2 | -0.0629646 |
| VCL | vinculin | -0.0626254 |
| RPS24 | ribosomal protein S24 | -0.0615835 |
| OGA | O-GlcNAcase | -0.0600821 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0564131 |
| AHNAK | AHNAK nucleoprotein | -0.0526268 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0521225 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0514411 |
| BICC1 | BicC family RNA binding protein 1 | -0.0511975 |
| TPM4 | tropomyosin 4 | -0.0483652 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0478999 |
| ACTG1 | actin gamma 1 | -0.047638 |
| FLNA | filamin A, alpha | -0.0464682 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0448974 |
| SPAG9 | sperm associated antigen 9 | -0.0444017 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0432764 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0431879 |
| RRBP1 | ribosome binding protein 1 | -0.0421511 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0415334 |
| POTEF | POTE ankyrin domain family, member F | -0.0413156 |
| RPLP0 | ribosomal protein, large, P0 | -0.040538 |
| DEK | DEK proto-oncogene | -0.0404783 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0387191 |
| RBM39 | RNA binding motif protein 39 | -0.0363496 |
| TXNRD1 | thioredoxin reductase 1 | -0.0362105 |
| SMAD3 | SMAD family member 3 | -0.0360338 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0357775 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0354785 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.035079 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0349785 |
| ANLN | anillin, actin binding protein | -0.0340364 |
| CAVIN1 | caveolae associated protein 1 | -0.0340235 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0338836 |
| THBS2 | thrombospondin 2 | -0.0333753 |
| RHOA | ras homolog family member A | -0.0332219 |
| TUBB | tubulin, beta class I | -0.0331942 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.0331397 |
| QKI | QKI, KH domain containing, RNA binding | -0.0331322 |
| HLA-C | major histocompatibility complex, class I, C | -0.0330377 |
| CD164 | CD164 molecule, sialomucin | -0.0328448 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0323845 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0322534 |
| ARF1 | ADP-ribosylation factor 1 | -0.0322095 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0316635 |
| RPL4 | ribosomal protein L4 | -0.0316502 |
| HLA-E | major histocompatibility complex, class I, E | -0.0315188 |
| CANX | calnexin | -0.0313811 |
| GNAS | GNAS complex locus | -0.0312882 |
| LAMP2 | lysosomal-associated membrane protein 2 | -0.0312045 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0309266 |
| RTN4 | reticulon 4 | -0.0304111 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0302343 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0302172 |
| COL1A1 | collagen, type I, alpha 1 | -0.0298559 |
| CENPF | centromere protein F, 350/400kDa | -0.0293601 |
| FSTL1 | follistatin-like 1 | -0.0290114 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0285957 |
| MAP1B | microtubule-associated protein 1B | -0.0282989 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0282324 |
| MKI67 | marker of proliferation Ki-67 | -0.0279248 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0277468 |
| TMEM123 | transmembrane protein 123 | -0.0274115 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0273367 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0270171 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.0270143 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0269874 |
| HDLBP | high density lipoprotein binding protein | -0.0266718 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0266297 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0264326 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0262659 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0261645 |
| CALR | calreticulin | -0.026158 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0261168 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0260999 |
| FAM20C | family with sequence similarity 20, member C | -0.0259094 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0258983 |
| SRGN | serglycin | -0.0258973 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0258362 |
| TMEM263 | transmembrane protein 263 | -0.0255449 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0254985 |
| HMGB2 | high mobility group box 2 | -0.0253639 |
| HBP1 | HMG-box transcription factor 1 | -0.0253575 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.025318 |
| IPO7 | importin 7 | -0.0250234 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | -0.0241933 |
| CD63 | CD63 molecule | -0.0240133 |
| NUP153 | nucleoporin 153kDa | -0.0238393 |
| TNNC1 | troponin C type 1 (slow) | -0.0238213 |
