| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Malotilate perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Malotilate_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.102235 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0928711 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0832228 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0700795 |
| OSMR | oncostatin M receptor | 0.0593246 |
| VCL | vinculin | 0.0571465 |
| HMGA2 | high mobility group AT-hook 2 | 0.054155 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0525306 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0439516 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0432384 |
| MKI67 | marker of proliferation Ki-67 | 0.0415488 |
| CENPF | centromere protein F, 350/400kDa | 0.0392023 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.038612 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0385977 |
| NRP1 | neuropilin 1 | 0.0377331 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0336302 |
| TMEM156 | transmembrane protein 156 | 0.0334277 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0331229 |
| PRELID2 | PRELI domain containing 2 | 0.0325524 |
| SMOX | spermine oxidase | 0.0321479 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0309383 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0305256 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0297848 |
| FLNA | filamin A, alpha | 0.0294524 |
| NTN4 | netrin 4 | 0.0281212 |
| TOP1 | topoisomerase (DNA) I | 0.0280156 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0276965 |
| ITGA1 | integrin, alpha 1 | 0.0276905 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0276151 |
| SEPTIN9 | septin 9 | 0.0272357 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0270714 |
| CD44 | CD44 molecule (Indian blood group) | 0.0268603 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0266857 |
| SMAD3 | SMAD family member 3 | 0.0257557 |
| ARRDC3 | arrestin domain containing 3 | 0.0250662 |
| RPL3 | ribosomal protein L3 | 0.0244159 |
| NAV2 | neuron navigator 2 | 0.0242123 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | 0.0241485 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0241146 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0238721 |
| GLIS3 | GLIS family zinc finger 3 | 0.0236768 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.0234401 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0234001 |
| EFNA5 | ephrin-A5 | 0.0232691 |
| ETV6 | ets variant 6 | 0.0230675 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0230344 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0227015 |
| SMYD3 | SET and MYND domain containing 3 | 0.0224451 |
| ACTN1 | actinin, alpha 1 | 0.0224274 |
| PNN | pinin, desmosome associated protein | 0.0222189 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0221321 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0220722 |
| PCM1 | pericentriolar material 1 | 0.0219707 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0219605 |
| VMP1 | vacuole membrane protein 1 | 0.0219557 |
| SP3 | Sp3 transcription factor | 0.021828 |
| LOXL2 | lysyl oxidase-like 2 | 0.0217712 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0215061 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0211713 |
| SSH1 | slingshot protein phosphatase 1 | 0.0210041 |
| VEGFC | vascular endothelial growth factor C | 0.0202597 |
| FNBP1 | formin binding protein 1 | 0.0199825 |
| CDCP1 | CUB domain containing protein 1 | 0.0199255 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0197713 |
| ITGB5 | integrin, beta 5 | 0.0196692 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0195313 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0195162 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.019447 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0191947 |
| MSN | moesin | 0.0191778 |
| MEF2D | myocyte enhancer factor 2D | 0.0191527 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0189054 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0188957 |
| EGFR | epidermal growth factor receptor | 0.0188535 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0188137 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0187687 |
| FAM219A | family with sequence similarity 219, member A | 0.0184186 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0184089 |
| NRG1 | neuregulin 1 | 0.0183996 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0183715 |
| CAB39 | calcium binding protein 39 | 0.0182838 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0181521 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0181209 |
| PELO | pelota homolog (Drosophila) | 0.0181158 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0179437 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0178656 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0177289 |
| RRBP1 | ribosome binding protein 1 | 0.017645 |
| ETV1 | ets variant 1 | 0.0174675 |
| ATXN1 | ataxin 1 | 0.0174164 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0173834 |
| FHL2 | four and a half LIM domains 2 | 0.0173817 |
| VEGFA | vascular endothelial growth factor A | 0.0172786 |
| USP34 | ubiquitin specific peptidase 34 | 0.0172553 |
| HMGB3 | high mobility group box 3 | 0.0171885 |
| TPM3 | tropomyosin 3 | 0.0171098 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0171016 |
| PLEC | plectin | 0.017082 |
| FLNB | filamin B, beta | 0.0170151 |
| RAD51B | RAD51 paralog B | 0.0169218 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.287223 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.192174 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.111326 |
| FTL | ferritin, light polypeptide | -0.101551 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0946601 |
| TMSB10 | thymosin beta 10 | -0.091465 |
| PTMA | prothymosin, alpha | -0.0900449 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0773544 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.076564 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0750457 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0729532 |
| MT2A | metallothionein 2A | -0.0714142 |
| RPL35A | ribosomal protein L35a | -0.0708831 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0702436 |
| S100A6 | S100 calcium binding protein A6 | -0.0677026 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0665418 |
| HLA-B | major histocompatibility complex, class I, B | -0.0636597 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0625588 |
| RPLP1 | ribosomal protein, large, P1 | -0.0620461 |
| LMNA | lamin A/C | -0.0601061 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0570944 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0564088 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0535771 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0522283 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0511835 |
| GNAS | GNAS complex locus | -0.0505245 |
| RPS20 | ribosomal protein S20 | -0.0486746 |
| RLF | rearranged L-myc fusion | -0.0479316 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.047532 |
| CANX | calnexin | -0.0467517 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.046637 |
| RAB1A | RAB1A, member RAS oncogene family | -0.046415 |
| RPS19 | ribosomal protein S19 | -0.0464015 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0454499 |
| RPS24 | ribosomal protein S24 | -0.0444929 |
| H1-0 | H1.0 linker histone | -0.0443893 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0441818 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0440717 |
| QKI | QKI, KH domain containing, RNA binding | -0.0437139 |
| RPL26 | ribosomal protein L26 | -0.0437074 |
| RPL34 | ribosomal protein L34 | -0.0433195 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0428607 |
| VIM | vimentin | -0.0427555 |
| IER3 | immediate early response 3 | -0.0425035 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0423455 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0420882 |
| RPS21 | ribosomal protein S21 | -0.0420878 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0419719 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0419374 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0419125 |
| S100A10 | S100 calcium binding protein A10 | -0.0408656 |
| RPS6 | ribosomal protein S6 | -0.0403035 |
| HBP1 | HMG-box transcription factor 1 | -0.0400314 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0398634 |
| RNF145 | ring finger protein 145 | -0.0397095 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.0381072 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0377777 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.036434 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0363509 |
| SQSTM1 | sequestosome 1 | -0.0363059 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0359103 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0352485 |
| DENND5B | DENN/MADD domain containing 5B | -0.0350125 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0347678 |
| HMGA1 | high mobility group AT-hook 1 | -0.0346653 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0346372 |
| TMEM263 | transmembrane protein 263 | -0.0342119 |
| USP3 | ubiquitin specific peptidase 3 | -0.0340414 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0337401 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0335896 |
| HELZ | helicase with zinc finger | -0.0333358 |
| SEPTIN7 | septin 7 | -0.0328148 |
| RHEB | Ras homolog enriched in brain | -0.0328035 |
| RPS25 | ribosomal protein S25 | -0.0327945 |
| RPS8 | ribosomal protein S8 | -0.0327221 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0321713 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0318128 |
| GOLT1B | golgi transport 1B | -0.0317809 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0315078 |
| TMSB4X | thymosin beta 4, X-linked | -0.0313248 |
| FBXW11 | F-box and WD repeat domain containing 11 | -0.0313191 |
| RPL37 | ribosomal protein L37 | -0.0312755 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0312697 |
| DSTN | destrin (actin depolymerizing factor) | -0.0311326 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0310792 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.03101 |
| RPLP0 | ribosomal protein, large, P0 | -0.030926 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0307854 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0306398 |
| RPL12 | ribosomal protein L12 | -0.0306344 |
| YBX3 | Y box binding protein 3 | -0.0303231 |
| EMP1 | epithelial membrane protein 1 | -0.0303096 |
| PARD3 | par-3 family cell polarity regulator | -0.0300671 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0298747 |
| RPS27 | ribosomal protein S27 | -0.029841 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0294701 |
| RPL32 | ribosomal protein L32 | -0.0293314 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0292743 |
| ARF1 | ADP-ribosylation factor 1 | -0.0289877 |
| MTDH | metadherin | -0.0283864 |
