Marginal Zone B-Cell Lymphoma Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A B-cell lymphoma that is characterized by initial formation in the marginal zones of lymph tissue. (Human Disease Ontology, DOID_0050748)
External Link https://www.disgenet.org/browser/0/1/0/C1367654
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Genes

114 genes associated with the disease Marginal Zone B-Cell Lymphoma in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
AICDA activation-induced cytidine deaminase
AKT1 v-akt murine thymoma viral oncogene homolog 1
ARR3 arrestin 3, retinal (X-arrestin)
ATM ATM serine/threonine kinase
BCL10 B-cell CLL/lymphoma 10
BCL2 B-cell CLL/lymphoma 2
BCL6 B-cell CLL/lymphoma 6
BIRC3 baculoviral IAP repeat containing 3
BTLA B and T lymphocyte associated
BTNL2 butyrophilin-like 2
C1QC complement component 1, q subcomponent, C chain
CARD11 caspase recruitment domain family, member 11
CASP10 caspase 10, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASR calcium-sensing receptor
CCND1 cyclin D1
CD19 CD19 molecule
CD200 CD200 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CIB1 calcium and integrin binding 1 (calmyrin)
CRNN cornulin
CXADR coxsackie virus and adenovirus receptor
CXCR3 chemokine (C-X-C motif) receptor 3
CXCR4 chemokine (C-X-C motif) receptor 4
CXCR5 chemokine (C-X-C motif) receptor 5
DRC1 dynein regulatory complex subunit 1
DSP desmoplakin
FAS Fas cell surface death receptor
FBXW8 F-box and WD repeat domain containing 8
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23)
FCRL1 Fc receptor-like 1
FCRL4 Fc receptor-like 4
FOXP1 forkhead box P1
GCSAM germinal center-associated, signaling and motility
GPR34 G protein-coupled receptor 34
HLA-B major histocompatibility complex, class I, B
HLA-G major histocompatibility complex, class I, G
ICAM1 intercellular adhesion molecule 1
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1)
IGH immunoglobulin heavy locus
IKZF3 IKAROS family zinc finger 3 (Aiolos)
IL12A interleukin 12A
IL13 interleukin 13
IL2RA interleukin 2 receptor, alpha
IL7R interleukin 7 receptor
IRF4 interferon regulatory factor 4
JAK2 Janus kinase 2
KALRN kalirin, RhoGEF kinase
KNTC1 kinetochore associated 1
KRT20 keratin 20, type I
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LMO2 LIM domain only 2 (rhombotin-like 1)
LOC102723407 putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8
LOC102724971 putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8
LOC105379528 Ig heavy chain V region 5A-like
LPL lipoprotein lipase
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MALT1 MALT1 paracaspase
MCL1 myeloid cell leukemia 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MEF2B myocyte enhancer factor 2B
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
MLH1 mutL homolog 1
MME membrane metallo-endopeptidase
MNDA myeloid cell nuclear differentiation antigen
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MUM1 melanoma associated antigen (mutated) 1
MXI1 MAX interactor 1, dimerization protein
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYD88 myeloid differentiation primary response 88
NBN nibrin
NCOA5 nuclear receptor coactivator 5
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
NLRP2 NLR family, pyrin domain containing 2
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
NOTCH2 notch 2
NR1I3 nuclear receptor subfamily 1, group I, member 3
PAX5 paired box 5
PDLIM5 PDZ and LIM domain 5
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PTPRJ protein tyrosine phosphatase, receptor type, J
RAD50 RAD50 homolog (S. cerevisiae)
RHOH ras homolog family member H
ROR1 receptor tyrosine kinase-like orphan receptor 1
RTEL1 regulator of telomere elongation helicase 1
SLC35B2 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SOX11 SRY (sex determining region Y)-box 11
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive)
SPN sialophorin
STMN1 stathmin 1
TLR1 toll-like receptor 1
TLR10 toll-like receptor 10
TLR2 toll-like receptor 2
TLR6 toll-like receptor 6
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TP53 tumor protein p53
TRAF3 TNF receptor-associated factor 3
TRIM13 tripartite motif containing 13
TYMS thymidylate synthetase
VCAM1 vascular cell adhesion molecule 1
VMP1 vacuole membrane protein 1
ZBTB46 zinc finger and BTB domain containing 46
ZMIZ1 zinc finger, MIZ-type containing 1