Maternal Hypertension Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description Increased blood pressure during a pregnancy. (Human Phenotype Ontology, HP_0008071)
External Link https://www.disgenet.org/browser/0/1/0/C0565599
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Genes

50 genes associated with the disease Maternal Hypertension in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACE angiotensin I converting enzyme
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
AMH anti-Mullerian hormone
ANGPT2 angiopoietin 2
APLN apelin
ATF3 activating transcription factor 3
AUTS2 autism susceptibility candidate 2
CCHCR1 coiled-coil alpha-helical rod protein 1
CD46 CD46 molecule, complement regulatory protein
CFH complement factor H
CFI complement factor I
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3
COL1A1 collagen, type I, alpha 1
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial
FA2H fatty acid 2-hydroxylase
FBN1 fibrillin 1
GRK4 G protein-coupled receptor kinase 4
GSTP1 glutathione S-transferase pi 1
HPGDS hematopoietic prostaglandin D synthase
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
IGF1R insulin-like growth factor 1 receptor
LPL lipoprotein lipase
MIPEP mitochondrial intermediate peptidase
MMP1 matrix metallopeptidase 1
MMP2 matrix metallopeptidase 2
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
MPO myeloperoxidase
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NOS3 nitric oxide synthase 3 (endothelial cell)
NR3C2 nuclear receptor subfamily 3, group C, member 2
PEX1 peroxisomal biogenesis factor 1
PGF placental growth factor
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTHLH parathyroid hormone-like hormone
REN renin
RENBP renin binding protein
SELENBP1 selenium binding protein 1
SHBG sex hormone-binding globulin
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
TIMP1 TIMP metallopeptidase inhibitor 1
TNF tumor necrosis factor
TRIM8 tripartite motif containing 8
VPS51 vacuolar protein sorting 51 homolog (S. cerevisiae)
ZMPSTE24 zinc metallopeptidase STE24