| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Mebendazole perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Mebendazole_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ACTG1 | actin gamma 1 | 0.154542 |
| AREG | amphiregulin | 0.144382 |
| PTMA | prothymosin, alpha | 0.107251 |
| TMSB10 | thymosin beta 10 | 0.0992407 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0848162 |
| MKI67 | marker of proliferation Ki-67 | 0.0679135 |
| CALR | calreticulin | 0.0653998 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | 0.0642224 |
| CCN2 | cellular communication network factor 2 | 0.0621018 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0592554 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0592205 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0565809 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0548858 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0534805 |
| RPS3 | ribosomal protein S3 | 0.0490944 |
| RPL7A | ribosomal protein L7a | 0.0483705 |
| RPL23 | ribosomal protein L23 | 0.047128 |
| RPL37A | ribosomal protein L37a | 0.047022 |
| RPL35A | ribosomal protein L35a | 0.0458971 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0437542 |
| RRM2 | ribonucleotide reductase M2 | 0.0435996 |
| RPL19 | ribosomal protein L19 | 0.0427785 |
| RPS27A | ribosomal protein S27a | 0.040527 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0396224 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0377694 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0372286 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0365967 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0364452 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0352393 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0346004 |
| RPL9 | ribosomal protein L9 | 0.0345362 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0339151 |
| RPL38 | ribosomal protein L38 | 0.033589 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.033238 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0326256 |
| RPL13A | ribosomal protein L13a | 0.0322701 |
| RPS29 | ribosomal protein S29 | 0.0319488 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0318846 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.030771 |
| RPL4 | ribosomal protein L4 | 0.0306584 |
| ANKRD12 | ankyrin repeat domain 12 | 0.030015 |
| RPL26 | ribosomal protein L26 | 0.0299603 |
| RPL3 | ribosomal protein L3 | 0.0296593 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0294242 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0291806 |
| ASPH | aspartate beta-hydroxylase | 0.0283064 |
| EZR | ezrin | 0.0280619 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0278632 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.0275468 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0275131 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0272718 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0269115 |
| PRDX1 | peroxiredoxin 1 | 0.0265741 |
| PDCD5 | programmed cell death 5 | 0.0262737 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0262119 |
| FLNA | filamin A, alpha | 0.0256798 |
| RPL37 | ribosomal protein L37 | 0.0256071 |
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | 0.0252127 |
| CACYBP | calcyclin binding protein | 0.0249219 |
| CAVIN1 | caveolae associated protein 1 | 0.0245554 |
| MAGEA4 | melanoma antigen family A4 | 0.0245342 |
| FUS | FUS RNA binding protein | 0.0242758 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.024132 |
| RPS19 | ribosomal protein S19 | 0.0239258 |
| SPAG5 | sperm associated antigen 5 | 0.0235109 |
| RPS17 | ribosomal protein S17 | 0.0233583 |
| THRAP3 | thyroid hormone receptor associated protein 3 | 0.0230221 |
| YBX1 | Y box binding protein 1 | 0.0223504 |
| HNRNPUL2 | heterogeneous nuclear ribonucleoprotein U-like 2 | 0.0220323 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | 0.0220225 |
| DDX23 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 | 0.0220171 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0213383 |
| DRAP1 | DR1-associated protein 1 (negative cofactor 2 alpha) | 0.0210772 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | 0.0210467 |
| YBX3 | Y box binding protein 3 | 0.020695 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0205633 |
| MAPRE1 | microtubule-associated protein, RP/EB family, member 1 | 0.0205567 |
| MTCL1 | microtubule crosslinking factor 1 | 0.0203247 |
| STIP1 | stress-induced phosphoprotein 1 | 0.0202603 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0201066 |
| RPS23 | ribosomal protein S23 | 0.0200851 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0199566 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.019844 |
| CEP250 | centrosomal protein 250kDa | 0.0198353 |
| CHD4 | chromodomain helicase DNA binding protein 4 | 0.0197686 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0197556 |
| CMIP | c-Maf inducing protein | 0.0197015 |
| BRD8 | bromodomain containing 8 | 0.0194756 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0194364 |
| HLA-B | major histocompatibility complex, class I, B | 0.0194207 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.019367 |
| RPS7 | ribosomal protein S7 | 0.0192839 |
| RPL31 | ribosomal protein L31 | 0.0191546 |
| ZC3H13 | zinc finger CCCH-type containing 13 | 0.0189609 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0188548 |
| RPLP1 | ribosomal protein, large, P1 | 0.0186077 |
| DENND5A | DENN/MADD domain containing 5A | 0.0185804 |
| SF3A1 | splicing factor 3a, subunit 1, 120kDa | 0.0184348 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0182445 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0181156 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.165181 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.15623 |
| MMP12 | matrix metallopeptidase 12 | -0.115887 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.108341 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.10337 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.100029 |
| NLGN1 | neuroligin 1 | -0.0949907 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0931612 |
| USP34 | ubiquitin specific peptidase 34 | -0.0914393 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0826 |
| PFN1 | profilin 1 | -0.0802311 |
| VIM | vimentin | -0.0772302 |
| VMP1 | vacuole membrane protein 1 | -0.0766305 |
| TENM3 | teneurin transmembrane protein 3 | -0.0734961 |
| DST | dystonin | -0.0646892 |
| JMJD1C | jumonji domain containing 1C | -0.0633346 |
| XPO1 | exportin 1 | -0.0630177 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0612219 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0606614 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0595899 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0569273 |
| NF1 | neurofibromin 1 | -0.0541146 |
| TMEM123 | transmembrane protein 123 | -0.0536963 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.053632 |
| TUBA1B | tubulin, alpha 1b | -0.0529641 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0522569 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0517031 |
| PCBP2 | poly(rC) binding protein 2 | -0.0511613 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.05115 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0509645 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0508515 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0491789 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0488988 |
| ZNF292 | zinc finger protein 292 | -0.0479123 |
| RPLP0 | ribosomal protein, large, P0 | -0.0464554 |
| IL6ST | interleukin 6 signal transducer | -0.0458703 |
| HMGA1 | high mobility group AT-hook 1 | -0.0457695 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0453915 |
| CXADR | coxsackie virus and adenovirus receptor | -0.045084 |
| TPI1 | triosephosphate isomerase 1 | -0.0448545 |
| MGAT4C | MGAT4 family, member C | -0.0431052 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0423808 |
| MED13L | mediator complex subunit 13-like | -0.0422159 |
| YAP1 | Yes-associated protein 1 | -0.0419757 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0414092 |
| ZNF207 | zinc finger protein 207 | -0.0413893 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0411334 |
| TXNRD1 | thioredoxin reductase 1 | -0.0406424 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0396103 |
| EPHA6 | EPH receptor A6 | -0.0395806 |
| RTN3 | reticulon 3 | -0.0393542 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0388967 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0387389 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.038597 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0381283 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0376595 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0371512 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0370366 |
| CDK6 | cyclin-dependent kinase 6 | -0.0368584 |
| RAD51B | RAD51 paralog B | -0.036656 |
| SYT1 | synaptotagmin I | -0.0366287 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0364786 |
| ERBIN | erbb2 interacting protein | -0.0364137 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0362157 |
| DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | -0.0356969 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0352905 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0347565 |
| PCNP | PEST proteolytic signal containing nuclear protein | -0.0346867 |
| H1-0 | H1.0 linker histone | -0.0344736 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0343792 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0342511 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0341545 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | -0.0339851 |
| SETD5 | SET domain containing 5 | -0.0337342 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0334501 |
| NEK7 | NIMA-related kinase 7 | -0.0334359 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0332785 |
| KLHL24 | kelch-like family member 24 | -0.0325934 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0320242 |
| DTNA | dystrobrevin, alpha | -0.0320156 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0315512 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.031542 |
| NEBL | nebulette | -0.0313035 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0312457 |
| NKTR | natural killer cell triggering receptor | -0.0312084 |
| ELP4 | elongator acetyltransferase complex subunit 4 | -0.0303475 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0301253 |
| TFG | TRK-fused gene | -0.0298812 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0293343 |
| USP14 | ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) | -0.0293119 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0291974 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.02907 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0289887 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0288027 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.028636 |
| CCND1 | cyclin D1 | -0.0286214 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0284608 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | -0.0284019 |
| SKIL | SKI-like proto-oncogene | -0.0283862 |
| AFF4 | AF4/FMR2 family, member 4 | -0.028379 |
