| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Mebendazole perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Mebendazole_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.0965256 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0939887 |
| SMAD3 | SMAD family member 3 | 0.0934432 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0807628 |
| CALR | calreticulin | 0.0775746 |
| DST | dystonin | 0.0741218 |
| SDC4 | syndecan 4 | 0.0707657 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.067964 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0617158 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0616022 |
| PADI1 | peptidyl arginine deiminase, type I | 0.0580147 |
| TNNC1 | troponin C type 1 (slow) | 0.0572773 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0534958 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0521164 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0508278 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0500543 |
| MLPH | melanophilin | 0.0478207 |
| TXNIP | thioredoxin interacting protein | 0.0476244 |
| DIAPH1 | diaphanous-related formin 1 | 0.0475128 |
| MYO5B | myosin VB | 0.0474401 |
| APP | amyloid beta (A4) precursor protein | 0.0468779 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0466736 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0457612 |
| TMSB4X | thymosin beta 4, X-linked | 0.0453626 |
| SFTPA2 | surfactant protein A2 | 0.0452841 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0448481 |
| ANXA2 | annexin A2 | 0.0439092 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0427095 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0419952 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.041612 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0410539 |
| NCKAP5 | NCK-associated protein 5 | 0.0405172 |
| ZC3H13 | zinc finger CCCH-type containing 13 | 0.0394896 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0380966 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0377637 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0376028 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0374557 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0368991 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0364252 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0350201 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0342544 |
| CYTH1 | cytohesin 1 | 0.0342173 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0336269 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0332262 |
| CDK5RAP3 | CDK5 regulatory subunit associated protein 3 | 0.0330309 |
| SH3PXD2A | SH3 and PX domains 2A | 0.0329833 |
| BICRAL | BICRA like chromatin remodeling complex associated protein | 0.0328614 |
| AHNAK | AHNAK nucleoprotein | 0.0327995 |
| VEGFA | vascular endothelial growth factor A | 0.0324569 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0318658 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0317869 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0317374 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.031225 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0309041 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0308121 |
| ACTG1 | actin gamma 1 | 0.0307122 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0307101 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0304018 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | 0.0300885 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0294193 |
| TSPYL2 | TSPY-like 2 | 0.0292429 |
| ASPH | aspartate beta-hydroxylase | 0.029154 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0291149 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0290122 |
| COPG1 | coatomer protein complex, subunit gamma 1 | 0.0287957 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0285202 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0284316 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.028383 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0279041 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0278474 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0277852 |
| ADM | adrenomedullin | 0.0275371 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0275277 |
| PHF3 | PHD finger protein 3 | 0.027497 |
| CTSB | cathepsin B | 0.0272612 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0271342 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0269921 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0267153 |
| RPN1 | ribophorin I | 0.0264864 |
| NDRG1 | N-myc downstream regulated 1 | 0.0264001 |
| ATXN1 | ataxin 1 | 0.0262999 |
| LMO7 | LIM domain 7 | 0.0262616 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.02614 |
| HYOU1 | hypoxia up-regulated 1 | 0.0258102 |
| HPCAL1 | hippocalcin-like 1 | 0.0255379 |
| LASP1 | LIM and SH3 protein 1 | 0.0253481 |
| HLA-C | major histocompatibility complex, class I, C | 0.0253304 |
| ZNF841 | zinc finger protein 841 | 0.0250394 |
| RPL7A | ribosomal protein L7a | 0.0249529 |
| RAPGEF1 | Rap guanine nucleotide exchange factor (GEF) 1 | 0.0245103 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0244724 |
| OARD1 | O-acyl-ADP-ribose deacylase 1 | 0.0244418 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | 0.0244076 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0243634 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0242406 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0240283 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.0239218 |
| ERP44 | endoplasmic reticulum protein 44 | 0.023903 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0236953 |
| NEK6 | NIMA-related kinase 6 | 0.0236069 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.150152 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.131723 |
| EGR1 | early growth response 1 | -0.104302 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0981567 |
| MACC1 | metastasis associated in colon cancer 1 | -0.086521 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0852566 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0816515 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.076639 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0754464 |
| LYZ | lysozyme | -0.0741295 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0740911 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0719783 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0699961 |
| SPATA13 | spermatogenesis associated 13 | -0.0691954 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0674454 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -0.0654435 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0616306 |
| EZR | ezrin | -0.0612089 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0605425 |
| RIGI | RNA sensor RIG-I | -0.0593201 |
| PTMA | prothymosin, alpha | -0.0566402 |
| VMP1 | vacuole membrane protein 1 | -0.0561227 |
| PLSCR1 | phospholipid scramblase 1 | -0.056031 |
| ERBIN | erbb2 interacting protein | -0.0547346 |
| SERINC5 | serine incorporator 5 | -0.0541467 |
| EPHB2 | EPH receptor B2 | -0.0539388 |
| MX2 | MX dynamin-like GTPase 2 | -0.0534422 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0532879 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0532837 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0512715 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0503205 |
| TRIM2 | tripartite motif containing 2 | -0.0503056 |
| XAF1 | XIAP associated factor 1 | -0.0481687 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0474635 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0462531 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0461321 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0454291 |
| ITGA6 | integrin, alpha 6 | -0.0450283 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0437241 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0436925 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0435965 |
| JUN | jun proto-oncogene | -0.0429555 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0428613 |
| SLC38A1 | solute carrier family 38, member 1 | -0.042803 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0422702 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0419209 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0415741 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0413886 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0405574 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0403316 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0402199 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0399884 |
| MYO1E | myosin IE | -0.0392899 |
| B2M | beta-2-microglobulin | -0.039044 |
| MEIS2 | Meis homeobox 2 | -0.0387597 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0382387 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0375965 |
| CMPK1 | cytidine monophosphate (UMP-CMP) kinase 1, cytosolic | -0.0373265 |
| H1-0 | H1.0 linker histone | -0.0368995 |
| FTL | ferritin, light polypeptide | -0.0366884 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0366026 |
| MT2A | metallothionein 2A | -0.0364027 |
| WDR45B | WD repeat domain 45B | -0.0356358 |
| TMC5 | transmembrane channel-like 5 | -0.035268 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0350006 |
| FOXP1 | forkhead box P1 | -0.0349162 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0345205 |
| DSTN | destrin (actin depolymerizing factor) | -0.0344841 |
| TMEM62 | transmembrane protein 62 | -0.033854 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.032946 |
| AREG | amphiregulin | -0.0327386 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0321334 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.032025 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0319735 |
| ZNF609 | zinc finger protein 609 | -0.0311174 |
| GRK3 | G protein-coupled receptor kinase 3 | -0.0308208 |
| NPSR1 | neuropeptide S receptor 1 | -0.0307608 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0306972 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0305341 |
| VIM | vimentin | -0.0304267 |
| KRT19 | keratin 19, type I | -0.0302965 |
| MUC13 | mucin 13, cell surface associated | -0.0298954 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0295493 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0295081 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0293362 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.029021 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0288415 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0288289 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0286457 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0286317 |
| HLA-E | major histocompatibility complex, class I, E | -0.0285471 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0284797 |
| RPS24 | ribosomal protein S24 | -0.0283333 |
| INTS6 | integrator complex subunit 6 | -0.028196 |
| RPL34 | ribosomal protein L34 | -0.0281705 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0279598 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0278963 |
| ETV6 | ets variant 6 | -0.027564 |
| SQSTM1 | sequestosome 1 | -0.0270956 |
| PER2 | period circadian clock 2 | -0.026633 |
